In vitro and in vivo models for monkeypox.

The emergence and rapid spread outside of monkeypox virus (MPXV) to non-endemic areas has led to another global health emergency in the midst of the COVID-19 pandemic. The scientific community has sought to rapidly develop in vitro and in vivo models that could be applied in research with MPXV. In vitro models include two-dimensional (2D) cultures of immortalized cell lines or primary cells and three-dimensional (3D) cultures. In vitro models are considered cost-effective and can be done in highly controlled conditions; however, they do not always resemble physiological conditions. In this way, several in vivo models are being characterized to meet the growing demand for new studies related to MPXV. In this review, we summarize the main MPXV models that have already been developed and discuss how they can contribute to advance the understanding of its pathogenesis, replication, and transmission, as well as identifying antivirals to treat infected patients.

Global overview of pharmacist and community pharmacy actions to address COVID-19: A scoping review.

Introduction: Pharmacists and community pharmacies play an important role in managing, identifying and preventing the spread of the COVID-19 outbreak. Objectives: To characterize the global panorama of action by pharmacists and community pharmacies in facing the COVID-19 pandemic. Methods: The scoping review was based on the search for scientific articles in the databases: PubMed; Scopus; ScienceDirect and Web of Science. The search was carried out on August 31, 2021. The selection process was divided into 3 phases: i) title analysis; ii) analysis of study abstracts; iii) analysis of the full texts of the studies selected in the previous step. Studies were independently selected by two investigators and discrepancies resolved by consensus during focus group discussions led by a third reviewer. Results: The final search yielded 36 articles for the review. The main strategies for coping with COVID-19 were grouped into 4 categories defined by consensus between the authors: (1) services for providing care to the patient; (2) product management; (3) infection prevention and control practices in community pharmacy; (4) preparation, sources of information used and training offered/received. Through these, the aim was to involve technical managerial, technical assistance and pedagogical technical actions adopted, as well as structure and process indicators that allowed the continuity of the offer of services. Conclusion: During the pandemic, pharmacists and community pharmacies have been providing essential health services to communities. The results of this review may help to identify the changes adopted to face the COVID-19 pandemic and may contribute to improving the quality of practices in these establishments during the pandemic and after it, in similar situations.

Attributable mortality due to nosocomial sepsis in Brazilian hospitals: a case-control study.

BACKGROUND: Nosocomial sepsis is a major healthcare issue, but there are few data on estimates of its attributable mortality. We aimed to estimate attributable mortality fraction (AF) due to nosocomial sepsis. METHODS: Matched 1:1 case-control study in 37 hospitals in Brazil. Hospitalized patients in participating hospitals were included. Cases were hospital non-survivors and controls were hospital survivors, which were matched by admission type and date of discharge. Exposure was defined as occurrence of nosocomial sepsis, defined as antibiotic prescription plus presence of organ dysfunction attributed to sepsis without an alternative reason for organ failure; alternative definitions were explored. Main outcome measurement was nosocomial sepsis-attributable fractions, estimated using inversed-weight probabilities methods using generalized mixed model considering time-dependency of sepsis occurrence. RESULTS: 3588 patients from 37 hospitals were included. Mean age was 63 years and 48.8% were female at birth. 470 sepsis episodes occurred in 388 patients (311 in cases and 77 in control group), with pneumonia being the most common source of infection (44.3%). Average AF for sepsis mortality was 0.076 (95% CI 0.068-0.084) for medical admissions; 0.043 (95% CI 0.032-0.055) for elective surgical admissions; and 0.036 (95% CI 0.017-0.055) for emergency surgeries. In a time-dependent analysis, AF for sepsis rose linearly for medical admissions, reaching close to 0.12 on day 28; AF plateaued earlier for other admission types (0.04 for elective surgery and 0.07 for urgent surgery). Alternative sepsis definitions yield different estimates. CONCLUSION: The impact of nosocomial sepsis on outcome is more pronounced in medical admissions and tends to increase over time. The results, however, are sensitive to sepsis definitions.

Complex systems design based on actual system functioning: Coping with variability in a national water ambulances service.

BACKGROUND: In Brazil, the Mobile Emergency Medical Service (SAMU) is a model of mobile assistance and care for emergencies standardized throughout the country. The water ambulance service within the SAMU operates in riverside and coastal areas, and faces challenges and peculiarities that increase the complexity of providing a high-quality and safe emergency care service. OBJECTIVE: To develop organizational design guidelines aiming to improve resilient performance of complex systems, with an application to riverine and coastal mobile emergency care in Brazil. METHODS: Data collection followed an ethnographic approach. Fieldwork was carried in a participatory way, based on worksite technical description, semi-structured interviews with managers and emergency care teams' professionals, and work observation whenever possible. Five regional SAMU coordinations were visited. Data coding employed content analysis and grouped data excerpts according to concepts of capacity and demand. Interfaces were identified between demand and capacity elements and adaptations led by system agents, orienting the proposal of guidelines for organizational design as solutions to face the verified gaps. RESULTS: Design guidelines produced spanned composition and training of both intervention teams and dispatch central teams, uniforms and personal protective equipment (PPE), decentralized water bases, means of communication, intervention protocols, biosafety and inter-sector actions. CONCLUSION: The approach enabled framing and assessment of specific design elements according to resilience engineering concepts, which in turn showed paths for improving the service and reconciling work-as-imagined and actual system functioning.

On the brink of disruption: Applying Resilience Engineering to anticipate system performance under crisis.

As COVID-19 spread across Brazil, it quickly reached remote regions including Amazon's ultra-peripheral locations where patient transportation through rivers is added to the list of obstacles to overcome. This article analyses the pandemic's effects in the access of riverine communities to the prehospital emergency healthcare system in the Brazilian Upper Amazon River region. To do so, we present two studies that by using a Resilience Engineering approach aimed to predict the functioning of the Brazilian Mobile Emergency Medical Service (SAMU) for riverside and coastal areas during the COVID-19 pandemic, based on the normal system functioning. Study I, carried out before the pandemic, applied ethnographic methods for data collection and the Functional Resonance Analysis Method - FRAM for data analysis in order to develop a model of the mobile emergency care in the region during typical conditions of operation. Study II then estimated how changes in variability dynamics would alter system functioning during the pandemic, arriving at three trends that could lead the service to collapse. Finally, the accuracy of predictions is discussed after the pandemic first peaked in the region. Findings reveal that relatively small changes in variability dynamics can deliver strong implications to operating care and safety of expeditions aboard water ambulances. Also, important elements that add to the resilient capabilities of the system are extra-organizational, and thus during the pandemic safety became jeopardized as informal support networks grew fragile. Using FRAM for modelling regular operation enabled prospective scenario analysis that accurately predicted disruptions in providing emergency care to riverine population.

[Aging, facing strategies of the aged and the consequences for family]. / Envelhecimento, estratégias de enfrentamento do idoso e repercussões na família.

This qualitative study seeks the understanding of the perception of the elderly, users of Basic Health Unit of São Paulo, on aging, coping strategies and impact on family. Interviews with three elderly people, from 71 to 90 years-old, were held from September 2007 to July'2008. Participants responded to questions under the Geriatric Depression Scale, Ecomapa, Genogram and Calgary model. From the Bardin analysis, we could determine three categories - the moment of realizing the life cycle; suffering the consequences of this time; facing the aging and old age. We believe in the continuity of studies that search for strategies with older people and their families in an attempt to improve life quality and family dynamics by the inclusion of entertainment, according to the possibilities offered to their communities.

Psychosocial aspects and the impact of oral health on quality of life of Brazilian adults. / Aspectos psicossociais e percepção de impacto da saúde bucal na qualidade de vida em adultos do Sul do Brasil.

INTRODUCTION: This research aimed to investigate the association between psychosocial aspects and the impact of oral health on quality of life among adults. METHOD: This population-based cross-sectional study was conducted with 1,100 adults aged 20 years or older from a medium-sized city in Rio Grande do Sul, Southern Brazil. The outcome was Oral Health Impact Profile (OHIP-14) in three categories: better (OHIP=0: 50% of lower scores), moderate (OHIP 1-12.6: 25% of intermediate scores), and worse (OHIP≥12.7: 25% of higher scores). The exposures included measurements of social support, resilience, sense of coherence, spirituality, quality of life, and stress. We calculated crude and adjusted odds ratios and their respective 95% confidence intervals using ordinal logistic regression. RESULTS: After adjustment for demographic, socioeconomic, and behavioral variables, individuals with low social support, low sense of coherence, low quality of life, and high level of stress were, respectively, 2.16, 2.90, 2.94, and 1.50 times more likely to report a worse impact of oral health on quality of life than those with favorable characteristics. CONCLUSIONS: The findings suggest that psychosocial aspects can influence the perceived impact of oral health on quality of life. Health policies, programs, and services must recognize the mutual relationship between oral health indicators and psychosocial aspects among adults.

INTRODUÇÃO: A pesquisa objetivou investigar a associação entre os aspectos psicossociais e o impacto das condições bucais sobre a qualidade de vida de adultos, escopo ainda pouco explorado em pesquisas nacionais. MÉTODO: Um estudo transversal de base populacional foi realizado com 1.100 adultos de 20 anos de idade ou mais, em uma cidade de médio porte do Rio Grande do Sul. O desfecho foi avaliado por meio do Oral Health Impact Profile (OHIP-14) enquanto as exposições incluíram medidas de apoio social, resiliência, senso de coerência, espiritualidade, qualidade de vida e estresse. Foram calculadas as razões de chances brutas e ajustadas, bem como seus intervalos de confiança de 95% utilizando-se regressão logística ordinal. RESULTADOS: Após o ajuste para variáveis demográficas, socioeconômicas e comportamentais, indivíduos com baixo apoio social, baixo senso de coerência, baixa qualidade de vida e alto nível de estresse possuíam respectivamente 2,16; 2,90; 2,94; 1,50 vezes mais chance de relatar um pior impacto da condição na qualidade de vida quando comparados aos indivíduos com estas características favoráveis. CONCLUSÕES: Os achados sugerem que os aspectos psicossociais podem influenciar a avaliação que as pessoas fazem do impacto da condição bucal sobre a qualidade de vida. É importante que políticas, programas e serviços de saúde reconheçam a relação mútua entre os indicadores de saúde bucal e os aspectos psicossociais de adultos.

Occasional finding of neurological disorders during children hearing loss evaluation using the ABR.

One of the most important applications of the Brainstem evoked response audiometry (ABR) is in the evaluation of hearing loss in children. Today the ABR is also indicated in the screening of cochleo-vestibular syndromes to detect retrocochlear lesions, to monitor patients in a coma (brain death), in monitoring the brainstem during skull base surgery, etc. Among the many BERA qualities, is its capacity to evaluate the neurophysiologic integrity of the auditory brainstem pathway. In doing so, sometimes while evaluating hearing function in children we are faced with ABR waves that suggest the presence of retrocochlear lesions (trace asymmetry, increased interpeak intervals), many times confirmed through image studies. These cases are seen as occasional findings of neurologic disorders during children hearing loss evaluation. In this study we report 2 cases of neurologic disorders diagnosed with the use of the ABR to evaluate hearing loss in children.

Prevalence of urinary incontinence, impact on quality of life and associated factors in users of Primary Health Care Units in Governador Valadares / Prevalência de incontinência urinária, impacto na qualidade de vida e fatores associados em usuárias de Unidades de Atenção Primária à Saúde

Abstract Introduction: Urinary incontinence (UI) has a considerable negative impact on quality of life, resulting in psychosocial, emotional and health impairment, high costs to the health system and limited activities of daily living. Objective: To describe the proportion of women with UI and its impact on quality of life (QOL), and investigate the factors associated with this condition among users of Primary Health Care Units (PHCUs) in the municipality of Governador Valadares, Minas Gerais state (MG), Brazil. Methods: Cross-sectional study with female users of the municipal PHCUs. A questionnaire compiled by the researchers was used for data collection. Participants who reported urine leakage in any situation completed the International Consultation on Incontinence Questionnaire - Short Form (ICIQ-SF). Results: A total of 201 women took part in the study, 36.32% of whom had UI and obtained a score of 7, indicating a moderate impact on their QOL. Urinary incontinence was associated with age, income, body mass index and parity. Conclusion: The proportion of women with UI corroborates the prevalence described by the International Continence Society (ICS), moderately impacting quality of life and indicating normalization of the problem. Urinary incontinence was also correlated with age, income, BMI and number of pregnancies. This demonstrates the need for health education strategies at PHCUs to prevent and treat UI in this group, as well as intersectoral activities to improve the income of the population in order to control modifiable risk factors.

Resumo Introdução: A incontinência urinária (IU) causa considerável impacto negativo na qualidade de vida, ocasionando prejuízo psicossocial, emocional e higiênico, além de alto custo para o sistema de saúde e limitações nas atividades de vida diária. Objetivo: Descrever a proporção de mulheres com IU e o seu impacto na qualidade de vida, bem como investigar os fatores associados a essa condição de saúde entre usuárias de Unidades de Atenção Primária à Saúde (UAPS) do município de Governador Valadares, MG. Métodos: Estudo transversal realizado entre mulheres usuárias de UAPS do município. Um questionário elaborado pelas pesquisadoras foi utilizado para coleta de dados. As participantes que relataram queixa de perda urinária em qualquer situação responderam ao International Consultation on Incontinence Questionnaire - Short Form (ICIQ-SF). Resultados: Participaram do estudo 201 mulheres. A proporção de mulheres com incontinência urinária foi de 36,32% e entre essas o escore do ICIQ-SF teve mediana igual a 7 pontos, indicando impacto moderado na qualidade de vida. A incontinência urinária associou-se à idade, renda, índice de massa corporal e paridade. Conclusão: A proporção de mulheres com IU está de acordo com a prevalência descrita pela International Continence Society (ICS), impactando moderadamente na qualidade de vida, o que indica uma normalização do problema. Ademais, a IU esteve associada à idade, renda, IMC e número de gestações. Assim, estratégias de educação em saúde para esse grupo são necessárias, a fim de prevenir e tratar a IU nas UAPS, bem como ações intersetoriais para melhorar a renda da população, no sentido de controlar os fatores de risco que são modificáveis.

Cryo-TEM investigation of phase behaviour and aggregate structure in dilute dispersions of monoolein and oleic acid.

Cryo-transmission electron microscopy (cryo-TEM) was used to image the microstructure in dilute sonicated dispersions of monoolein and oleic acid. The aim of the study was to explore how different experimental parameters, such as sample composition, total lipid concentration, pH, and ageing affect the phase behaviour and aggregate structure. Our investigations show that a rich variety of lamellar and non-lamellar structures, including liposomes and particles of cubic and inverted hexagonal phase, may form depending on the experimental conditions. The results are analyzed and discussed in relation to existing phase diagrams and earlier investigations concerning phase- and structural behaviour in monoolein/oleic acid/water systems.

Aspectos psicossociais e percepção de impacto da saúde bucal na qualidade de vida em adultos do Sul do Brasil / Psychosocial aspects and the impact of oral health on quality of life of Brazilian adults

RESUMO: Introdução: A pesquisa objetivou investigar a associação entre os aspectos psicossociais e o impacto das condições bucais sobre a qualidade de vida de adultos, escopo ainda pouco explorado em pesquisas nacionais. Método: Um estudo transversal de base populacional foi realizado com 1.100 adultos de 20 anos de idade ou mais, em uma cidade de médio porte do Rio Grande do Sul. O desfecho foi avaliado por meio do Oral Health Impact Profile (OHIP-14) enquanto as exposições incluíram medidas de apoio social, resiliência, senso de coerência, espiritualidade, qualidade de vida e estresse. Foram calculadas as razões de chances brutas e ajustadas, bem como seus intervalos de confiança de 95% utilizando-se regressão logística ordinal. Resultados: Após o ajuste para variáveis demográficas, socioeconômicas e comportamentais, indivíduos com baixo apoio social, baixo senso de coerência, baixa qualidade de vida e alto nível de estresse possuíam respectivamente 2,16; 2,90; 2,94; 1,50 vezes mais chance de relatar um pior impacto da condição na qualidade de vida quando comparados aos indivíduos com estas características favoráveis. Conclusões: Os achados sugerem que os aspectos psicossociais podem influenciar a avaliação que as pessoas fazem do impacto da condição bucal sobre a qualidade de vida. É importante que políticas, programas e serviços de saúde reconheçam a relação mútua entre os indicadores de saúde bucal e os aspectos psicossociais de adultos.

ABSTRACT: Introduction: This research aimed to investigate the association between psychosocial aspects and the impact of oral health on quality of life among adults. Method: This population-based cross-sectional study was conducted with 1,100 adults aged 20 years or older from a medium-sized city in Rio Grande do Sul, Southern Brazil. The outcome was Oral Health Impact Profile (OHIP-14) in three categories: better (OHIP=0: 50% of lower scores), moderate (OHIP 1-12.6: 25% of intermediate scores), and worse (OHIP≥12.7: 25% of higher scores). The exposures included measurements of social support, resilience, sense of coherence, spirituality, quality of life, and stress. We calculated crude and adjusted odds ratios and their respective 95% confidence intervals using ordinal logistic regression. Results: After adjustment for demographic, socioeconomic, and behavioral variables, individuals with low social support, low sense of coherence, low quality of life, and high level of stress were, respectively, 2.16, 2.90, 2.94, and 1.50 times more likely to report a worse impact of oral health on quality of life than those with favorable characteristics. Conclusions: The findings suggest that psychosocial aspects can influence the perceived impact of oral health on quality of life. Health policies, programs, and services must recognize the mutual relationship between oral health indicators and psychosocial aspects among adults.

Percepção Discente sobre o Ambiente Educacional da Disciplina de Semiologia Médica / Student's Perception of the Educational Environment within the Medical Semiology Subject

Resumo: Introdução: A Faculdade de Medicina da Universidade Federal de Goiás (FM-UFG) iniciou um novo processo de mudança curricular em 2014. As disciplinas de Semiologia I e II passaram a adotar metodologias ativas de ensino para adequação às necessidades da reforma curricular. O objetivo deste artigo foi avaliar a percepção dos discentes do primeiro ano da FM-UFG sobre o ambiente educacional das disciplinas de Semiologia I e II. Método: Trata-se de um estudo descritivo, do tipo corte transversal, envolvendo 86 alunos. O instrumento de coleta de dados foi o questionário Dundee Ready Education Environment Measure (Dreem), versão em português. Os resultados foram considerados em três níveis: questões individuais, cinco dimensões e Dreem global. Calcularam-se a média, o desvio padrão e os respectivos intervalos de confiança de 95%. Obteve-se a confiabilidade interna do Dreem pelo cálculo do alfa de Cronbach, avaliou-se a distribuição dos dados da amostra pelo teste de Shapiro-Wilk e realizou-se a comparação entre os percentuais da média dos escores dos domínios e do DRREM global pela ANOVA, seguida do teste de Tukey. Resultados: A média do Dreem global foi de 134,83/200 ± 17,42, uma percepção mais positiva que negativa. As cinco dimensões tiveram os seguintes resultados: percepção da aprendizagem (32,74 / 48 ± 5,59 / uma visão mais positiva); percepção dos docentes (32,71 / 44 ± 6,23 / na direção certa); percepção dos resultados acadêmicos (20,22 / 32 ± 4,09 / sentimento positivo); percepção do ambiente geral (31,74 / 48 ± 5,69 / atitude positiva); percepção das relações sociais (17,42 / 28 ± 3,83 / não é tão ruim). Foram encontrados alguns pontos problemáticos em relação a fatos memorizáveis, metodologia de ensino prévio e cansaço para cursarem a disciplina. A dimensão com mais áreas fortes foi a percepção dos docentes. Houve significância estatística quando os percentuais da média dos escores dos domínios e do Dreem global foram comparados. Conclusão: O ambiente educacional das disciplinas de Semiologia I e II da Faculdade de Medicina da UFG criado pelas inovações metodológicas foi avaliado positivamente pelos discentes participantes, com destaque para o domínio percepção dos docentes.

Abstract: Introduction: In 2014, the Medical School of the Federal University of Goias (FM-UFG) started its curricular changing process. The disciplines of Semiology I and II started to use active teaching methodologies to fit the curricular reform needs. The objective of this article was to evaluate the FM-UFG students' perception of the Educational Environment in the disciplines of Semiology I and II. Method: This is a descriptive, cross-sectional study encompassing 86 students. The data collection tool was the Dundee Ready Education Environment Measure (DREEM) questionnaire, in its Portuguese version. Results were considered at three levels: individual questions, five domains and global DREEM. Mean values, standard deviation and respective 95% confidence intervals were calculated. The internal reliability of the DREEM was determined using Cronbach's alpha; the sample normality was determined using the Shapiro-Wilk test; and the comparison between the mean score percentages of the domains and of the global DREEM was performed by ANOVA ,followed by Tukey's test. Results: The global DREEM mean was 134.83 / 200 ± 17.42, a more positive than negative perception. The five domains showed the following results: Students' Perception of Learning - SPL (32.74 / 48 ± 5.59 / a more positive approach); Students' Perception of Teachers - SPT (32.71 / 44 ± 6.23 / going in the right direction); Students' Academic Self-Perception - SASP: (20.22 / 32 ± 4.09 / feeling more on the positive side); Students' Perception of the Atmosphere - SPA (31.74 / 48 ± 5.69 / a more positive attitude); Students' Social Self-Perception - SSSP: (17.42 / 28 ± 3.83 / not too bad). Some issues were found in relation to: memorizable facts; previous teaching methodology; and, fatigue to attend the discipline. The SPT was the domain with the largest number of strong areas. Statistical significance was found when comparing the mean score percentages of the domains and the global DREEM. Conclusion: Students positively evaluated the educational environment in the subjects Semiology I and II created by the new active teaching methodologies adopted by the institution, with the SPT domain being highlighted.

Eagle's Syndrome.

INTRODUCTION: Eagle's syndrome is characterized by cervicopharyngeal signs and symptoms associated with elongation of the styloid apophysis. This elongation may occur through ossification of the stylohyoid ligament, or through growth of the apophysis due to osteogenesis triggered by a factor such as trauma. Elongation of the styloid apophysis may give rise to intense facial pain, headache, dysphagia, otalgia, buzzing sensations, and trismus. Precise diagnosis of the syndrome is difficult, and it is generally confounded by other manifestations of cervicopharyngeal pain. OBJECTIVE: To describe a case of Eagle's syndrome. CASE REPORT: A 53-year-old man reported lateral pain in his neck that had been present for 30 years. Computed tomography (CT) of the neck showed elongation and ossification of the styloid processes of the temporal bone, which was compatible with Eagle's syndrome. Surgery was performed for bilateral resection of the stylohyoid ligament by using a transoral and endoscopic access route. The patient continued to present pain laterally in the neck, predominantly on his left side. CT was performed again, which showed elongation of the styloid processes. The patient then underwent lateral cervicotomy with resection of the stylohyoid process, which partially resolved his painful condition. Final Comments: Patients with Eagle's syndrome generally have a history of chronic pain. Appropriate knowledge of this disease is necessary for adequate treatment to be provided. The importance of diagnosing this uncommon and often unsuspected disease should be emphasized, given that correct clinical-surgical treatment is frequently delayed. The diagnosis of Eagle's syndrome is clinical and radiographic, and the definitive treatment in cases of difficult-to-control pain is surgical.

Interaction of dodecaborate cluster compounds on hydrophilic column materials in water.

The interaction of a series of dodecaborate cluster compounds B(12)X(12)(2-) and B(12)X(11)Y(2-) (X=H, Cl, Br, I and Y=SH, OH, NR(3)) with hydrophilic column materials (Superdex 200, Sepharose 4B, Sephadex G-50, Sephadex G-100, alumina, silica gel and anion exchange material) was studied. Almost all the dodecaborate cluster compounds were retained strongly on Superdex 200. The halogenated cluster compounds interacted with Sepharose 4B, Sephadex G-50, Sephadex G-100 and alumina; on alumina, also the non-halogenated clusters were retained. Silica gel showed the least interaction with all compounds. The thermodynamic parameters were investigated for a selection of compounds on Superdex 200 and Sephadex G-100. Values for ΔH° were found to be negative on both gels. As the change in entropy ΔS° was also negative, it compensated ΔH° to a large extent. The clusters interacted also strongly with anion exchange material in ion chromatography; the interaction decreased with increasing acetonitrile concentration, implying a large contribution from solvent effects.

Cuidados de enfermagem para a prevenção de lesão de pele por adesivos em feridas cirúrgicas / Nursing care in the prevention of adhesive-related skin injuries in surgical wounds / Cuidados de enfermería para la prevención de lesión de piel por adhesivos en heridas quirúrgicas

Pesquisa convergente-assistencial que objetivou descrever os cuidados de enfermagem prestados pelo enfermeiro para prevenção de lesão de pele por adesivo em feridas cirúrgicas e analisar a adequação desses cuidados ao Consenso Internacional de Avaliação, Prevenção de Tratamento de Lesão por Adesivo. Participaram do estudo 10 enfermeiros que atuavam em uma Unidade de Terapia Intensiva Pediátrica. Os dados foram coletados entre julho e outubro de 2014, por meio de entrevistas individuais, e submetidos à análise de conteúdo temático. As informações coletadas sobre os cuidados implementados pelos participantes na escolha, aplicação e remoção de adesivos médicos foram problematizados e ficou clara a aproximação das falas com as recomendações do documento. Os cuidados descritos relacionam-se à aplicação, remoção e seleção dos insumos, configurando-se como cuidados preventivos para lesão por adesivos em feridas cirúrgicas com impacto na qualidade da assistência de enfermagem. [AU]

Convergent Care Research aimed to describe the nursing care offered by nurses in the prevention of adhesive-related skin injury in surgical wounds and analyze the applicability of this care based on the International Consensus Statements for the Assessment, Prevention, and Treatment of Adhesive-Related Skin Injuries. Ten nurses who worked in the scene between July and October 2014, period in which the data collection occurred, participated in this research. The interviews were realized individually. Thematic content analysis was applied. The information collected about the care implemented by participants in the selection, application and removal of medical adhesives was problematized, showing a clear relation between the reports of participants and the recommendations of the Consensus. The described care is related to the application, removal and selection of inputs, and it is characterized as preventive care for adhesive-related skin injury in surgical wounds with impact on the quality of nursing care. [AU]

Investigación convergente-asistencial que tuvo el objetivo de describir los cuidados de enfermería prestados por el enfermero para la prevención de lesión de piel por adhesivo en heridas quirúrgicas y analizar la adecuación de estos cuidados al Consenso Internacional de Evaluación, Prevención de Tratamiento de Lesión por Adhesivo. Participaron del estudio 10 enfermeros que actuaban en una Unidad de Cuidados Intensivos Pediátrica. Los datos fueron recolectados entre julio y octubre de 2014, mediante entrevistas individuales y sometidos al análisis de contenido temático. Las informaciones recolectadas sobre los cuidados implementados por los participantes en la elección, aplicación y remoción de adhesivos médicos fueron problematizados y quedó clara la aproximación de los relatos con las recomendaciones del documento. Los cuidados descriptos se relacionan a la aplicación, remoción y selección de los insumos, y se configuran como cuidados preventivos para lesión por adhesivos en heridas quirúrgicas con impacto en la calidad de la asistencia de enfermería. [AU]

[Sexual function and quality of life of low-risk pregnant women]. / Função sexual e qualidade de vida em gestantes de baixo risco.

PURPOSE: To evaluate, in healthy women in the second trimester of pregnancy, a possible association between sexual function and quality of life, and between sexual function and sexual satisfaction. METHODS: This cross-sectional study involved 51 pregnant women managed at a low-risk antenatal care clinic. Sexual function was evaluated through the Sexual Quotient - Female Version (QS-F) questionnaire. Quality of life and sexual satisfaction were evaluated though the brief version of the World Health Organization Quality of Life questionnaire (WHOQOL-bref). Inclusion criteria were pregnancy between 15-26 weeks, maternal age 20 or more years, at least five years of schooling, in a relationship with a single partner for the last 6 months, having sexual intercourse with vaginal penetration in the last 15 days. We excluded women with a history of sexual violence, previous or current depression, habitual abortion or obstetric complications in the index pregnancy (premature rupture of membranes, preterm labor or hemorrhage). The χ² and Fisher exact tests were used for statistical analyses and p<0.05 was considered significant. RESULTS: Most of the participants (64.8%) obtained "regular to excellent" grades on the QS-F and 58.8% classified their quality of life as "good". As to sexual satisfaction, 35.3 and 15.7% declared that they were "satisfied" and "very satisfied" with their sexual life, respectively. The study detected significant associations between "bad to poor" QS-F grades with a "poor" quality of life (p=0.002), and with "regular to good" and "good to excellent" QS-F grades with "satisfaction" or "high" sexual satisfaction" (p<0.001). CONCLUSIONS: Sexual function is associated with quality of life and with sexual satisfaction in healthy women in the second trimester of pregnancy.

[Prevalence and features of falls of institutionalized elders]. / Prevalência e caraterísticas das quedas de idosos institucionalizados.

This retrospective study seeks to check the prevalence of falls in older people from a long-term care institution for elderly people, in São Paulo, to describe the fallers and the events. We analyzed 121 medical records and 87 fall reports, between August 2006 and August 2007. There were 114 falls suffered by 45 ancians, a prevalence of 37,2%. The majority of fallers are women, average age 83,75 years. We found recurrent falls, various diagnoses and polipharmacy. The majority occurred in own height, in their bedroom, producing mainly hematomas. There is a need of implementation of fall preventive guidelines, due to the importance of this issue and its repercussions to the functional status of the institutionalized elderly.

Comment to "The pharmacopeial evolution of Intralipid injectable emulsion in plastic containers: from a coarse to a fine emulsion".

The droplet size distribution of 50 batches of multi-chamber bags containing the parenteral nutrition emulsions Intralipid (Kabiven and Kabiven Peripheral) or Structolipid (StructoKabiven and StructoKabiven Peripheral), respectively, has been investigated. The results show that the non-compounded lipid emulsions analysed are in compliance with the United States Pharmacopeia (USP) chapter 729, Method II limit for the droplet size distribution, PFAT(5)<0.05%.