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1.
Nature ; 555(7695): 197-203, 2018 03 08.
Artículo en Inglés | MEDLINE | ID: mdl-29466330

RESUMEN

Farming was first introduced to Europe in the mid-seventh millennium bc, and was associated with migrants from Anatolia who settled in the southeast before spreading throughout Europe. Here, to understand the dynamics of this process, we analysed genome-wide ancient DNA data from 225 individuals who lived in southeastern Europe and surrounding regions between 12000 and 500 bc. We document a west-east cline of ancestry in indigenous hunter-gatherers and, in eastern Europe, the early stages in the formation of Bronze Age steppe ancestry. We show that the first farmers of northern and western Europe dispersed through southeastern Europe with limited hunter-gatherer admixture, but that some early groups in the southeast mixed extensively with hunter-gatherers without the sex-biased admixture that prevailed later in the north and west. We also show that southeastern Europe continued to be a nexus between east and west after the arrival of farmers, with intermittent genetic contact with steppe populations occurring up to 2,000 years earlier than the migrations from the steppe that ultimately replaced much of the population of northern Europe.


Asunto(s)
Agricultores/historia , Genoma Humano/genética , Genómica , Migración Humana/historia , Agricultura/historia , Asia/etnología , ADN Antiguo , Europa (Continente) , Femenino , Genética de Población , Pradera , Historia Antigua , Humanos , Masculino , Distribución por Sexo
2.
Nat Commun ; 5: 5631, 2014 Dec 02.
Artículo en Inglés | MEDLINE | ID: mdl-25463651

RESUMEN

In 2012, a skeleton was excavated at the presumed site of the Grey Friars friary in Leicester, the last-known resting place of King Richard III. Archaeological, osteological and radiocarbon dating data were consistent with these being his remains. Here we report DNA analyses of both the skeletal remains and living relatives of Richard III. We find a perfect mitochondrial DNA match between the sequence obtained from the remains and one living relative, and a single-base substitution when compared with a second relative. Y-chromosome haplotypes from male-line relatives and the remains do not match, which could be attributed to a false-paternity event occurring in any of the intervening generations. DNA-predicted hair and eye colour are consistent with Richard's appearance in an early portrait. We calculate likelihood ratios for the non-genetic and genetic data separately, and combined, and conclude that the evidence for the remains being those of Richard III is overwhelming.


Asunto(s)
Cromosomas Humanos Y/genética , Dermatoglifia del ADN , ADN Mitocondrial/análisis , Genética Forense , Secuencia de Bases , Antropología Forense , Haplotipos , Humanos , Masculino , Datos de Secuencia Molecular , Paternidad
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