[Effectivity of intermittent RMP/EMB treatment in patients with chronic pulmonary tuberculosis (author's transl)]. / Effektivität von intermittierender RMP- und EMB-Behandlung bei Patienten mit chronischer Lungentuberkulose (Chronikerstudie)

59 patients with far advanced chronic pulmonary tuberculosis were treated, after a three months daily period of RMP/EMB and a third drug, with RMP 1.2 g and EMB 50 mg/kg twice weekly for the following 9 months and there after with EMB 50 mg/kg twice weekly for another 12 months. Sputumconversion was achieved in all patients within four months. Except for one bacteriological relapse during the 10th month of therapy all patients were TB-negative up to the end of at least four years (4-6 1/2 years) after onset of treatment. In nearly 78% of the patients the treatment was fully accepted and well tolerated during the first year. 8 patients had systemic reactions due to RMP between the 7th and 12th month. Only in 5 patients RMP had to be substituted by another drug. The regimen has proved to be highly effective, well acceptable and tolerable. It could be administered fully supervised.

[Effectivity of intermittent treatment in patients with sputum-positive silico-tuberculosis (author's transl)]. / Effektivität der intermittierenden Behandlung bei Patienten mit BK-positiver Siliko-Tuberkulose)

89 patients with sputum-positive silico-tuberculosis got a fully supervised administered antituberculous treatment with intermittent regimens during the years 1969-1974. 65 of the patients had a history of former antituberculous treatment. In only 5 patients the treatment was unsuccessful. Four of the relapses were observed between the 6th and 11th month of treatment. One patient had a relapse 56 months after the onset of chemotherapy. The results indicate that only the quality of the anti-TB treatment is of importance for the course of the tuberculous component in silico-tuberculosis. The results are comparable with those of uncomplicated TB of the lungs.

[Effect of pethidine administration on transcutaneous oxygen pressure in the fetus and pulmonary adaptation post natum]. / Auswirkung der Pethidinapplikation auf den transkutanen Sauerstoffdruck des Fetus und die pulmonale Adaptation post natum.

After application of Pethidine to the mother for the purpose of obstetric analgesia we couldn't find any changes in the fetal tcPO2-behaviour. As well 95 term infants with and without previous Pethidine-application to the mother showed no disturbance of cardio-pulmonary adaptation in hyperoxia-test.