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1.

SLC25A39 links mitochondrial GSH sensing with iron metabolism.

Chen, Xiong; Gan, Boyi.

Mol Cell ; 84(4): 616-618, 2024 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-38364779

2.

Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers.

Mao, Chao; Lei, Guang; Horbath, Amber; Wang, Min; Lu, Zhengze; Yan, Yuelong; Liu, Xiaoguang; Kondiparthi, Lavanya; Chen, Xiong; Cheng, Jun; Li, Qidong; Xu, Zhihao; Zhuang, Li; Fang, Bingliang; Marszalek, Joseph R; Poyurovsky, Masha V; Olszewski, Kellen; Gan, Boyi.

Mol Cell ; 84(10): 1964-1979.e6, 2024 May 16.

Artículo en Inglés | MEDLINE | ID: mdl-38759628

3.

The pyrimidinosome: Orchestrating pyrimidine biosynthesis and ferroptosis defense.

Gan, Boyi.

Mol Cell ; 83(16): 2837-2839, 2023 08 17.

Artículo en Inglés | MEDLINE | ID: mdl-37595553

4.

USP7 substrates identified by proteomics analysis reveal the specificity of USP7.

Nie, Litong; Wang, Chao; Liu, Xiaoguang; Teng, Hongqi; Li, Siting; Huang, Min; Feng, Xu; Pei, Guangsheng; Hang, Qinglei; Zhao, Zhongming; Gan, Boyi; Ma, Li; Chen, Junjie.

Genes Dev ; 36(17-18): 1016-1030, 2022 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-36302555

5.

A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia.

Shen, Xi; Wang, Rui; Kim, Moon Jong; Hu, Qianghua; Hsu, Chih-Chao; Yao, Jun; Klages-Mundt, Naeh; Tian, Yanyan; Lynn, Erica; Brewer, Thomas F; Zhang, Yilei; Arun, Banu; Gan, Boyi; Andreeff, Michael; Takeda, Shunichi; Chen, Junjie; Park, Jae-Il; Shi, Xiaobing; Chang, Christopher J; Jung, Sung Yun; Qin, Jun; Li, Lei.

Mol Cell ; 80(6): 1013-1024.e6, 2020 12 17.

Artículo en Inglés | MEDLINE | ID: mdl-33338401

6.

Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer.

Hu, Jian; Hwang, Soyoon Sarah; Liesa, Marc; Gan, Boyi; Sahin, Ergun; Jaskelioff, Mariela; Ding, Zhihu; Ying, Haoqiang; Boutin, Adam T; Zhang, Hailei; Johnson, Shawn; Ivanova, Elena; Kost-Alimova, Maria; Protopopov, Alexei; Wang, Yaoqi Alan; Shirihai, Orian S; Chin, Lynda; DePinho, Ronald A.

Cell ; 148(4): 651-63, 2012 Feb 17.

Artículo en Inglés | MEDLINE | ID: mdl-22341440

7.

Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases.

Ding, Zhihu; Wu, Chang-Jiun; Jaskelioff, Mariela; Ivanova, Elena; Kost-Alimova, Maria; Protopopov, Alexei; Chu, Gerald C; Wang, Guocan; Lu, Xin; Labrot, Emma S; Hu, Jian; Wang, Wei; Xiao, Yonghong; Zhang, Hailei; Zhang, Jianhua; Zhang, Jingfang; Gan, Boyi; Perry, Samuel R; Jiang, Shan; Li, Liren; Horner, James W; Wang, Y Alan; Chin, Lynda; DePinho, Ronald A.

Cell ; 148(5): 896-907, 2012 Mar 02.

Artículo en Inglés | MEDLINE | ID: mdl-22341455

8.

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.

Ying, Haoqiang; Kimmelman, Alec C; Lyssiotis, Costas A; Hua, Sujun; Chu, Gerald C; Fletcher-Sananikone, Eliot; Locasale, Jason W; Son, Jaekyoung; Zhang, Hailei; Coloff, Jonathan L; Yan, Haiyan; Wang, Wei; Chen, Shujuan; Viale, Andrea; Zheng, Hongwu; Paik, Ji-hye; Lim, Carol; Guimaraes, Alexander R; Martin, Eric S; Chang, Jeffery; Hezel, Aram F; Perry, Samuel R; Hu, Jian; Gan, Boyi; Xiao, Yonghong; Asara, John M; Weissleder, Ralph; Wang, Y Alan; Chin, Lynda; Cantley, Lewis C; DePinho, Ronald A.

Cell ; 149(3): 656-70, 2012 Apr 27.

Artículo en Inglés | MEDLINE | ID: mdl-22541435

9.

DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer.

Mao, Chao; Liu, Xiaoguang; Zhang, Yilei; Lei, Guang; Yan, Yuelong; Lee, Hyemin; Koppula, Pranavi; Wu, Shiqi; Zhuang, Li; Fang, Bingliang; Poyurovsky, Masha V; Olszewski, Kellen; Gan, Boyi.

Nature ; 593(7860): 586-590, 2021 05.

Artículo en Inglés | MEDLINE | ID: mdl-33981038

10.

A ferroptosis defense mechanism mediated by glycerol-3-phosphate dehydrogenase 2 in mitochondria.

Wu, Shiqi; Mao, Chao; Kondiparthi, Lavanya; Poyurovsky, Masha V; Olszewski, Kellen; Gan, Boyi.

Proc Natl Acad Sci U S A ; 119(26): e2121987119, 2022 06 28.

Artículo en Inglés | MEDLINE | ID: mdl-35749365

11.

Reply to: DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition.

Mao, Chao; Liu, Xiaoguang; Yan, Yuelong; Olszewski, Kellen; Gan, Boyi.

Nature ; 619(7968): E19-E23, 2023 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-37407682

12.

mTORC1 and ferroptosis: Regulatory mechanisms and therapeutic potential.

Lei, Guang; Zhuang, Li; Gan, Boyi.

Bioessays ; 43(8): e2100093, 2021 08.

Artículo en Inglés | MEDLINE | ID: mdl-34121197

13.

Spatial control of AMPK signaling at subcellular compartments.

Chauhan, Anoop Singh; Zhuang, Li; Gan, Boyi.

Crit Rev Biochem Mol Biol ; 55(1): 17-32, 2020 02.

Artículo en Inglés | MEDLINE | ID: mdl-32069425

14.

Author Correction: DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer.

Mao, Chao; Liu, Xiaoguang; Zhang, Yilei; Lei, Guang; Yan, Yuelong; Lee, Hyemin; Koppula, Pranavi; Wu, Shiqi; Zhuang, Li; Fang, Bingliang; Poyurovsky, Masha V; Olszewski, Kellen; Gan, Boyi.

Nature ; 596(7873): E13, 2021 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-34341547

15.

Targeting cancer stem cells with a pan-BCL-2 inhibitor in preclinical and clinical settings in patients with gastroesophageal carcinoma.

Song, Shumei; Chen, Qiongrong; Li, Yuan; Lei, Guang; Scott, Ailing; Huo, Longfei; Li, Cordelia Y; Estrella, Jeannelyn Santiano; Correa, Arlene; Pizzi, Melissa Pool; Ma, Lang; Jin, Jiankang; Liu, Bin; Wang, Ying; Xiao, Lianchun; Hofstetter, Wayne L; Lee, Jeffrey H; Weston, Brian; Bhutani, Manoop; Shanbhag, Namita; Johnson, Randy L; Gan, Boyi; Wei, Shaozhong; Ajani, Jaffer A.

Gut ; 70(12): 2238-2248, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-33487592

16.

Dodging death.

Yan, Yuelong; Gan, Boyi.

Nat Chem Biol ; 2024 May 08.

Artículo en Inglés | MEDLINE | ID: mdl-38720106

17.

Survival factor NFIL3 restricts FOXO-induced gene expression in cancer.

Keniry, Megan; Pires, Maira M; Mense, Sarah; Lefebvre, Celine; Gan, Boyi; Justiano, Karen; Lau, Ying-Ka Ingar; Hopkins, Ben; Hodakoski, Cindy; Koujak, Susan; Toole, Joseph; Fenton, Franklyn; Calahan, Ashley; Califano, Andrea; DePinho, Ronald A; Maurer, Matt; Parsons, Ramon.

Genes Dev ; 27(8): 916-27, 2013 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-23630076

18.

STIM2 interacts with AMPK and regulates calcium-induced AMPK activation.

Chauhan, Anoop Singh; Liu, Xiaoguang; Jing, Ji; Lee, Hyemin; Yadav, Raj Kumar; Liu, Jindou; Zhou, Yubin; Gan, Boyi.

FASEB J ; 33(2): 2957-2970, 2019 02.

Artículo en Inglés | MEDLINE | ID: mdl-30335546

19.

BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response.

Dai, Fangyan; Lee, Hyemin; Zhang, Yilei; Zhuang, Li; Yao, Hui; Xi, Yuanxin; Xiao, Zhen-Dong; You, M James; Li, Wei; Su, Xiaoping; Gan, Boyi.

Proc Natl Acad Sci U S A ; 114(12): 3192-3197, 2017 03 21.

Artículo en Inglés | MEDLINE | ID: mdl-28275095

20.

FoxO transcription factors in cancer metabolism.

Yadav, Raj Kumar; Chauhan, Anoop Singh; Zhuang, Li; Gan, Boyi.

Semin Cancer Biol ; 50: 65-76, 2018 06.

Artículo en Inglés | MEDLINE | ID: mdl-29309929

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