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1.

Urinary peptidomics in a rodent model of diabetic nephropathy highlights epidermal growth factor as a biomarker for renal deterioration in patients with type 2 diabetes.

Betz, Boris B; Jenks, Sara J; Cronshaw, Andrew D; Lamont, Douglas J; Cairns, Carolynn; Manning, Jonathan R; Goddard, Jane; Webb, David J; Mullins, John J; Hughes, Jeremy; McLachlan, Stela; Strachan, Mark W J; Price, Jackie F; Conway, Bryan R.

Kidney Int ; 89(5): 1125-1135, 2016 May.

Artículo en Inglés | MEDLINE | ID: mdl-27083286

2.

Top-down lipidomics of low density lipoprotein reveal altered lipid profiles in advanced chronic kidney disease.

Reis, Ana; Rudnitskaya, Alisa; Chariyavilaskul, Pajaree; Dhaun, Neeraj; Melville, Vanessa; Goddard, Jane; Webb, David J; Pitt, Andrew R; Spickett, Corinne M.

J Lipid Res ; 56(2): 413-22, 2015 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-25424003

3.

Endothelin-A receptor antagonism modifies cardiovascular risk factors in CKD.

Dhaun, Neeraj; Melville, Vanessa; Blackwell, Scott; Talwar, Dinesh K; Johnston, Neil R; Goddard, Jane; Webb, David J.

J Am Soc Nephrol ; 24(1): 31-6, 2013 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-23243212

4.

Mechanisms for an effect of acetylcysteine on renal function after exposure to radio-graphic contrast material: study protocol.

Sandilands, Euan A; Cameron, Sharon; Paterson, Frances; Donaldson, Sam; Briody, Lesley; Crowe, Jane; Donnelly, Julie; Thompson, Adrian; Johnston, Neil R; Mackenzie, Ivor; Uren, Neal; Goddard, Jane; Webb, David J; Megson, Ian L; Bateman, Nicholas; Eddleston, Michael.

BMC Clin Pharmacol ; 12: 3, 2012 Feb 03.

Artículo en Inglés | MEDLINE | ID: mdl-22305183

5.

Acetylcysteine has No Mechanistic Effect in Patients at Risk of Contrast-Induced Nephropathy: A Failure of Academic Clinical Science.

Sandilands, Euan A; Rees, Jessica M B; Raja, Khuram; Dhaun, Neeraj; Morrison, Emma E; Hickson, Kirsty; Wraight, Jonathan; Gray, Tanya; Briody, Lesley; Cameron, Sharon; Thompson, Adrian P; Johnston, Neil R; Uren, Neal; Goddard, Jane; Treweeke, Andy; Rushworth, Gordon; Webb, David J; Bateman, D Nicholas; Norrie, John; Megson, Ian L; Eddleston, Michael.

Clin Pharmacol Ther ; 111(6): 1222-1238, 2022 06.

Artículo en Inglés | MEDLINE | ID: mdl-35098531

6.

Selective and mixed endothelin receptor antagonism in cardiovascular disease.

Dhaun, Neeraj; Pollock, David M; Goddard, Jane; Webb, David J.

Trends Pharmacol Sci ; 28(11): 573-9, 2007 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-17950470

7.

The pharmacokinetic profile of sitaxsentan, a selective endothelin receptor antagonist, in varying degrees of renal impairment.

Dhaun, Neeraj; Melville, Vanessa; Kramer, William; Stavros, Fiona; Coyne, Terrance; Swan, Suzanne; Goddard, Jane; Webb, David J.

Br J Clin Pharmacol ; 64(6): 733-7, 2007 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-17635499

8.

First-in-Man Demonstration of Direct Endothelin-Mediated Natriuresis and Diuresis.

Hunter, Robert W; Moorhouse, Rebecca; Farrah, Tariq E; MacIntyre, Iain M; Asai, Takae; Gallacher, Peter J; Kerr, Debbie; Melville, Vanessa; Czopek, Alicja; Morrison, Emma E; Ivy, Jess R; Dear, James W; Bailey, Matthew A; Goddard, Jane; Webb, David J; Dhaun, Neeraj.

Hypertension ; 70(1): 192-200, 2017 07.

Artículo en Inglés | MEDLINE | ID: mdl-28507171

9.

An endothelin antagonist for resistant hypertension.

Dhaun, Neeraj; Goddard, Jane; Webb, David J.

Lancet ; 375(9715): 635; author reply 636-7, 2010 Feb 20.

Artículo en Inglés | MEDLINE | ID: mdl-20171390

10.

Endothelin-A receptor antagonism reduces blood pressure and increases renal blood flow in hypertensive patients with chronic renal failure: a comparison of selective and combined endothelin receptor blockade.

Goddard, Jane; Johnston, Neil R; Hand, Malcolm F; Cumming, Allan D; Rabelink, Ton J; Rankin, Andrew J; Webb, David J.

Circulation ; 109(9): 1186-93, 2004 Mar 09.

Artículo en Inglés | MEDLINE | ID: mdl-14981006

11.

Plasma pro-endothelin-1 peptide concentrations rise in chronic kidney disease and following selective endothelin A receptor antagonism.

Dhaun, Neeraj; Yuzugulen, Jale; Kimmitt, Robert A; Wood, Elizabeth G; Chariyavilaskul, Pajaree; MacIntyre, Iain M; Goddard, Jane; Webb, David J; Corder, Roger.

J Am Heart Assoc ; 4(3): e001624, 2015 Mar 23.

Artículo en Inglés | MEDLINE | ID: mdl-25801761

12.

Diurnal variation in blood pressure and arterial stiffness in chronic kidney disease: the role of endothelin-1.

Dhaun, Neeraj; Moorhouse, Rebecca; MacIntyre, Iain M; Melville, Vanessa; Oosthuyzen, Wilna; Kimmitt, Robert A; Brown, Kayleigh E; Kennedy, Ewan D; Goddard, Jane; Webb, David J.

Hypertension ; 64(2): 296-304, 2014 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-24890823

13.

Prospective management of end-stage renal failure within a conservative care programme.

Dhaun, Neeraj; Mackenzie, Johanna; Goddard, Jane; Whitworth, Caroline.

BMJ Qual Improv Rep ; 2(1)2013.

Artículo en Inglés | MEDLINE | ID: mdl-26734158

14.

N-acetylcysteine for contrast nephropathy: more clinical science is required.

Eddleston, Michael; Goddard, Jane; Bateman, Nick.

Arch Intern Med ; 166(15): 1668-9; author reply 1669, 2006.

Artículo en Inglés | MEDLINE | ID: mdl-16908804

15.

What is the best method of proteinuria measurement in clinical trials of endothelin receptor antagonists?

Towler, Jonathan D; Dhaun, Neeraj; MacDougall, Margaret; Melville, Vanessa; Goddard, Jane; Webb, David J.

Life Sci ; 91(13-14): 733-8, 2012 Oct 15.

Artículo en Inglés | MEDLINE | ID: mdl-22406074

16.

Risk factors for metabolic syndrome independently predict arterial stiffness and endothelial dysfunction in patients with chronic kidney disease and minimal comorbidity.

Lilitkarntakul, Pajaree; Dhaun, Neeraj; Melville, Vanessa; Kerr, Debbie; Webb, David J; Goddard, Jane.

Diabetes Care ; 35(8): 1774-80, 2012 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-22648437

17.

Endothelin antagonism in patients with nondiabetic chronic kidney disease.

Dhaun, Neeraj; Goddard, Jane; Webb, David J.

Contrib Nephrol ; 172: 243-254, 2011.

Artículo en Inglés | MEDLINE | ID: mdl-21894004

18.

Selective endothelin-A receptor antagonism reduces proteinuria, blood pressure, and arterial stiffness in chronic proteinuric kidney disease.

Dhaun, Neeraj; MacIntyre, Iain M; Kerr, Debbie; Melville, Vanessa; Johnston, Neil R; Haughie, Scott; Goddard, Jane; Webb, David J.

Hypertension ; 57(4): 772-9, 2011 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-21357275

19.

Blood pressure and not uraemia is the major determinant of arterial stiffness and endothelial dysfunction in patients with chronic kidney disease and minimal co-morbidity.

Lilitkarntakul, Pajaree; Dhaun, Neeraj; Melville, Vanessa; Blackwell, Scott; Talwar, Dinesh K; Liebman, Barbara; Asai, Takae; Pollock, Jennifer; Goddard, Jane; Webb, David J.

Atherosclerosis ; 216(1): 217-25, 2011 May.

Artículo en Inglés | MEDLINE | ID: mdl-21376323

20.

Acute renal dysfunction following hip fracture.

Bennet, Simon J; Berry, Olivia M B; Goddard, Jane; Keating, John F.

Injury ; 41(4): 335-8, 2010 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-19729159

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