Development and Validation of a Short Form of the Geriatric Anxiety Scale (GAS-12) among Italian Older Adults.

OBJECTIVES: We developed a new Italian short version of the Geriatric Anxiety Scale (GAS-12) and evaluated its psychometric properties. The GAS-12 specifically screens for anxiety symptoms in the Italian older adult population by identifying items that best discriminate anxiety in this population. METHODS: In Study 1, we administered the full-length Italian translation of the GAS to 517 older adults and used item response theory to identify the most discriminating items and to develop the short form used in Study 2. In Study 2, we evaluated the functioning of the new short form of the questionnaire in a new sample of 427 older adults using Confirmatory factor analysis. RESULTS: Analyses indicated 12 items that discriminated well between anxious and non-anxious participants and distributed along the latent continuum of each trait. The GAS-12 fits a three-factor structure. There was also evidence for convergent and divergent validity. CONCLUSIONS: The Italian GAS-12 appears to be a useful instrument for the quantitative screening of anxiety in Italian older adults. CLINICAL IMPLICATIONS: Anxiety imposes significant impairment thus making imperative the screening and assessment of anxiety symptoms. The GAS-12 is particularly indicated with limited time and many scales in a clinical assessment or research protocols.

Measuring Anxiety in Older Adults: Development, Diagnostic Accuracy, and Preliminary Validation of a Short-Form of the German Geriatric Anxiety Scale (GAS-G-SF).

Anxiety symptoms and anxiety disorders are highly prevalent among older adults, and are associated with considerable distress, functional impairment, and burden. Also, there is growing need for brief instruments to measure anxiety symptoms in primary care and geriatric medical settings. Therefore, the current study focuses on the development and psychometric evaluation of a short-form of the Geriatric Anxiety Scale (GAS-G), a well-established anxiety instrument for use with older adults. Study 1 draws on the original data from the GAS-G validation study (N = 242) to develop the short-form (GAS-G-SF) and determines whether the results replicate with the short-form. Study 2 extends the validation of the GAS-G-SF to a clinical sample (N = 156; 62 patients with heart disease, 94 patients with Parkinson's disease). Overall, the GAS-G-SF showed promising psychometric properties in terms of internal consistency and validity. Also, the GAS-G-SF showed good discriminatory power based on receiver operating characteristic curve analysis in both studies. These results support the utility of the GAS-G-SF as a brief assessment measure for anxiety.

SES-of-Origin and BMI in Youth: Comparing Germany and Minnesota.

Increasing obesity is a world-wide health concern. Its most commonly used indicator, body mass index (BMI), consistently shows considerable genetic and shared environmental variance throughout life, the latter particularly in youth. Several adult studies have observed less total and genetically influenced variance with higher attained SES. These studies offer clues about sources of the 'obesity epidemic' but analogous youth studies of SES-of-origin are needed. Genetic and environmental influences and moderating effects of SES may vary in countries with different health policies, lifestyles, and degrees/sources of social inequality, offering further clues to the sources of the obesity epidemic. We examined SES-of-origin moderation of BMI variance in the German TwinLife study's cohorts assessed around ages 5, 11, 17, and 23-24, and in the Minnesota Twin Family Study's (MTFS) 11- and 17-year-old birth cohorts assessed longitudinally around ages 11, 17, and 23-24, comparing male and female twins and their parents. Age for age, both sexes' means and variances were greater in MTFS than in TwinLife. We observed that SES generally moderated genetic influences, more strongly in females, similar to most adult studies of attained-SES moderation of BMI. We interpreted differences in our SES-of-origin observations in light of inevitably-missing covariance between SES-of-origin and BMI in the models, mother-father and parent-offspring BMI correlations, and parental attained-SES-BMI correlations. We suggest that one source of the present obesity epidemic is social change that amplifies expression of genes both constraining SES attainment and facilitating weight gain.

An investigation of the psychometric properties of the Geriatric Anxiety Scale (GAS) in an Italian sample of community-dwelling older adults.

BACKGROUND: The Italian older adult population is increasing and psychiatric problems, such as anxiety among older adults, represent major challenges for public welfare. A strong need exists for instruments specifically developed to assess anxiety among Italian older adults. The Geriatric Anxiety Scale (GAS) is a 30-item self-report questionnaire that evaluates anxiety among older adults and has demonstrated strong psychometric properties in several languages. OBJECTIVE: The present study aimed to validate an Italian version of the GAS (GAS-I) and to preliminarily investigate its psychometric properties. METHOD: The translation was performed using a five-stage procedure, following a forward-back process and paying attention to cultural issues. The GAS-I was administered to 231 community-dwelling older adults with other commonly-used questionnaires of anxiety, depression, and quality of life. RESULTS: Results confirmed good psychometric qualities of the questionnaire. Confirmatory factor analyses evidenced a unidimensional structure of the GAS-I, in accordance with other validated versions. Convergent and discriminant validity were highly satisfactory. The three-factor model also provided an acceptable fit to the data. Receiver operating characteristic curve analyses revealed good discriminatory power of the GAS-I. CONCLUSION: These findings demonstrate that the GAS-I is a reliable and valid self-report questionnaire to measure anxiety among Italian older adults.

Validation of a Chinese Version of the Geriatric Anxiety Scale Among Community-Dwelling Older Adults in Mainland China.

The Geriatric Anxiety Scale (GAS) was developed as an international screening instrument for anxiety in older adults. The aims of the present study were to translate the GAS into Chinese and to subsequently evaluate the preliminary psychometric properties of the Chinese version of the GAS (GAS-C) among community-dwelling Chinese older adults. The translation of the GAS into Chinese was developed through a translation and back translation process. A sample of 206 community-dwelling older adults (51.9 % men, Mean age = 70.70 years, SD = 8.15 years) completed the GAS-C, the Beck Anxiety Inventory (BAI), the Geriatric Depression Scale (GDS) and the Pittsburgh Sleep Quality Index (PSQI). A confirmatory factor analysis was conducted to examine the factor structure of the GAS-C. Internal consistency and convergent validity were used to evaluate the psychometric properties of the translated measure. The factor analyses were in support of a unidimensional factor model of the GAS-C in this Chinese sample, and the item-total correlations for all 25 items ranged from 0.40 to 0.83. The internal consistency for the GAS-C total score was excellent (α = 0.92). The GAS-C total score were significantly and strongly correlated with the BAI (r = 0.86), the GDS (r = 0.78) and the PSQI (r = 0.63), which indicated good convergent validity of the GAS-C. The GAS-C appears to be a reliable and valid screening instrument to assess anxiety symptoms among community-dwelling older adults in mainland China.

Genetic and Environmental Parent-Child Transmission of Value Orientations: An Extended Twin Family Study.

Despite cross-cultural universality of core human values, individuals differ substantially in value priorities, whereas family members show similar priorities to some degree. The latter has often been attributed to intrafamilial socialization. The analysis of self-ratings on eight core values from 399 twin pairs (ages 7-11) and their biological parents (388 mothers, 249 fathers; ages 26-65) allowed the disentanglement of environmental from genetic transmission accounting for family resemblance in value orientations. Results indicated that parent-child similarity is primarily due to shared genetic makeup. The primary source of variance in value priorities represented environmental influences that are not shared by family members. These findings do not provide evidence for parental influences beyond genetic influences contributing to intrafamilial similarity in value priorities.

What Drives the Development of Social Inequality Over the Life Course? The German TwinLife Study.

The German twin family study 'TwinLife' was designed to enhance our understanding of the development of social inequalities over the life course. The interdisciplinary project investigates mechanisms of social inequalities across the lifespan by taking into account psychological as well as social mechanisms, and their genetic origin as well as the interaction and covariation between these factors. Main characteristics of the study are: (1) a multidimensional perspective on social inequalities, (2) the assessment of developmental trajectories in childhood, adolescence, and young adulthood in a longitudinal design by using (3) a combination of a multi-cohort cross-sequential and an extended twin family design, while (4) capturing a large variation of behavioral and environmental factors in a representative sample of about 4,000 German twin families. In the present article, we first introduce the theoretical and empirical background of the TwinLife study, and second, describe the design, content, and implementation of TwinLife. Since the data will be made available as scientific use file, we also illustrate research possibilities provided by this project to the scientific community.

Relationships among depressive, passive-aggressive, sadistic and self-defeating personality disorder features with suicidal ideation and reasons for living among older adults.

OBJECTIVES: Suicide among older adults is a major public health problem in the USA. In our recent study, we examined relationships between the 10 standard DSM-5 personality disorders (PDs) and suicidal ideation, and found that the PD dimensions explained a majority (55%) of the variance in suicidal ideation. To extend this line of research, the purpose of the present follow-up study was to explore relationships between the four PDs that previously were included in prior versions of the DSM (depressive, passive-aggressive, sadistic, and self-defeating) with suicidal ideation and reasons for living. METHOD: Community-dwelling older adults (N = 109; age range = 60-95 years; 61% women; 88% European-American) completed anonymously the Coolidge Axis II Inventory, the Reasons for Living Inventory (RFL), and the Geriatric Suicide Ideation Scale (GSIS). RESULTS: Correlational analyses revealed that simple relationships between PD scales with GSIS subscales were generally stronger than with RFL subscales. Regarding GSIS subscales, all four PD scales had medium-to-large positive relationships, with the exception of sadistic PD traits, which was unrelated to the death ideation subscale. Multiple regression analyses showed that the amount of explained variance for the GSIS (48%) was higher than for the RFL (11%), and this finding was attributable to the high predictive power of depressive PD. CONCLUSION: These findings suggest that depressive PD features are strongly related to increased suicidal thinking and lowered resilience to suicide among older adults. Assessment of depressive PD features should also be especially included in the assessment of later-life suicidal risk.

Why children differ in motivation to learn: Insights from over 13,000 twins from 6 countries.

Little is known about why people differ in their levels of academic motivation. This study explored the etiology of individual differences in enjoyment and self-perceived ability for several school subjects in nearly 13,000 twins aged 9-16 from 6 countries. The results showed a striking consistency across ages, school subjects, and cultures. Contrary to common belief, enjoyment of learning and children's perceptions of their competence were no less heritable than cognitive ability. Genetic factors explained approximately 40% of the variance and all of the observed twins' similarity in academic motivation. Shared environmental factors, such as home or classroom, did not contribute to the twin's similarity in academic motivation. Environmental influences stemmed entirely from individual specific experiences.

Current twin studies in Germany: report on CoSMoS, SOEP, and ChronoS.

This article summarizes the status of three recent German twin studies: CoSMoS, SOEP, and ChronoS. The German twin study on Cognitive Ability, Self-Reported Motivation, and School Achievement (CoSMoS) is a three-wave longitudinal study of monozygotic and dizygotic twins reared together, and aims to investigate predictors of and influences on school performance. In the first wave of the data collection in 2005, 408 pairs of twins aged between 7 and 11 as well as their parents participated in CoSMoS. The SOEP twin study is an extended twin study, which has combined data from monozygotic and dizygotic twins reared together with additional data from full sibling pairs, mother-child, and grandparent-child dyads who participated in the German Socio-Economic Panel (GSOEP) study. The SOEP twin project comprises about 350 twin and 950 non-twin pairs aged between 17 and 70. Data were collected between 2009 and 2010, with a focus on personality traits, wellbeing, education, employment, income, living situation, life-satisfaction, and several attitudes. The aim of the Chronotype twin study (ChronoS) was to examine genetic and environmental influences on chronotype (morningness and eveningness), coping strategies, and several aspects of the previous SOEP twin project in a sample of 301 twin pairs aged between 19 and 76 years, recruited in 2010 and 2011. Part of the ChronoS twin sample also participated in the earlier SOEP twin study, representing a second wave of assessments. We briefly describe the design and contents of these three studies as well as selected recent findings.

Persian version of the Geriatric Anxiety Scale: translation and preliminary psychometric properties among Iranian older adults.

OBJECTIVE: The Geriatric Anxiety Scale (GAS) is a new self-report screening measure designed for older adults. Due to the burgeoning Iranian population of older adults and the need for validated, culturally-appropriate screening measures for anxiety in Iran, the purposes of the present study were to translate the GAS into Persian and to explore its preliminary psychometric properties. METHOD: Iranian older adults (N = 295; M age = 67.0 years) completed the GAS and the Iranian version of the Geriatric Depression Scale (GDS-15). RESULTS: Cronbach's alpha for the GAS total score and the GAS subscales were excellent (Total score α = .92; Cognitive α = .81; Somatic α = .84; Affective α = .80). As expected, each subscale was significantly positively correlated (all p's < .01) with the other subscales. The subscales share common variance ranging from 42% to 56%. The GAS total score and GAS subscale scores were significantly positively correlated with the GDS-15, with medium effect sizes (GAS Total r = .55; Cognitive r = .51; Somatic r = .50; Affective r = .48). Finally, exploratory and confirmatory factor analyses were conducted to investigate the factor structure of the Persian version of the GAS. Results support a one factor solution (general anxiety) for this Iranian sample. CONCLUSION: This study provides preliminary psychometric support for the Persian version of the GAS as a screening measure for anxiety in Iranian older adults, with a one-dimensional factor structure.

The Fight against Infectious Diseases: The Essential Role of Higher-Order Thinking and Problem-Solving.

The development of a vaccine marks a breakthrough in the fight against infectious diseases. However, to eradicate highly infectious diseases globally, the immunization of large parts of the population is needed. Otherwise, diseases, such as polio, measles, or more recently COVID-19, will repeatedly flare-up, with devastating effects on individuals and, in the worst case, on significant shares of the world population. For example, polio has been almost eradicated over the past three decades through an unprecedented global effort, but complete immunization has not yet been achieved. In this article, we use polio as an example to show how the global effort of developing and administering a vaccine can be understood as solving a complex problem since it involves cultural, political, and geographical barriers that demand solutions in dynamically changing and highly versatile environments. Referring to the literature on problem-solving, higher-order thinking, and complex reasoning, we demonstrate how the ability to deal with real-world environments that are complex and dynamically changing, adapting initial solutions to new circumstances and collaborate efficiently with others, has been essential for this endeavor. We argue that problem-solving abilities form one basis for solving consequential world problems.

Do nightmares and generalized anxiety disorder in childhood and adolescence have a common genetic origin?

The present study investigated the prevalence and heritability of nightmares and their comorbidity with psychopathology in a sample (N = 1,318) of children, adolescents, and child and adolescent twins ranging in age from 4 to 17 years old. The prevalence of terrible nightmares was estimated to be 6.4%, which is similar to previous studies. There were marginal gender differences in this rate (7.7% for boys; 5.1% in girls), contrary to previous studies that purport higher rates for girls. There was little evidence for prevalence changes across age. Nightmares were highly heritable and attributed to an additive genetic influence (51%) and nonshared environmental effects (49%). There was little evidence for a shared genetic correlation for nightmares and generalized waking anxiety (Overanxious Disorder of Childhood). There was also a substantial and pervasive comorbid psychopathology for those parents who reported Strongly True on Item 59: My child has terrible nightmares on the 200-item parent-as-respondent, Coolidge Personality and Neuropsychological Inventory. Issues in estimating prevalence rates of nightmares were identified.

Does the heritability of cognitive abilities vary as a function of parental education? Evidence from a German twin sample.

A well-known hypothesis in the behavioral genetic literature predicts that the heritability of cognitive abilities is higher in the presence of higher socioeconomic contexts. However, studies suggest that the effect of socioeconomic status (SES) on the heritability of cognitive ability may not be universal, as it has mostly been demonstrated in the United States, but not in other Western nations. In the present study we tested whether the importance of genetic and environmental effects on cognitive abilities varies as a function of parental education in a German twin sample. Cognitive ability scores (general, verbal, and nonverbal) were obtained on 531 German twin pairs (192 monozygotic, 339 dizygotic, ranging from 7 to 14 years of age; Mage = 10.25, SD = 1.83). Data on parental education were available from mothers and fathers. Results for general cognitive ability and nonverbal ability indicated no significant gene x parental education interaction effect. For verbal ability, a significant nonshared environment (E) x parental education interaction was found in the direction of greater nonshared environmental influences on verbal abilities among children raised by more educated parents.