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1.

SnapShot: Cancer Immunotherapy with Oncolytic Viruses.

Gujar, Shashi; Bell, John; Diallo, Jean-Simon.

Cell ; 176(5): 1240-1240.e1, 2019 02 21.

Artículo en Inglés | MEDLINE | ID: mdl-30794777

2.

Identification and characterization of calreticulin as a novel plasminogen receptor.

Bharadwaj, Alamelu G; Okura, Gillian C; Woods, John W; Allen, Erica A; Miller, Victoria A; Kempster, Emma; Hancock, Mark A; Gujar, Shashi; Slibinskas, Rimantas; Waisman, David M.

J Biol Chem ; 300(1): 105465, 2024 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-37979915

3.

Immune Checkpoint Blockade Augments Changes Within Oncolytic Virus-induced Cancer MHC-I Peptidome, Creating Novel Antitumor CD8 T Cell Reactivities.

Kim, Youra; Konda, Prathyusha; Murphy, J Patrick; Paulo, Joao A; Gygi, Steven P; Gujar, Shashi.

Mol Cell Proteomics ; 21(2): 100182, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-34922008

4.

Closely related reovirus lab strains induce opposite expression of RIG-I/IFN-dependent versus -independent host genes, via mechanisms of slow replication versus polymorphisms in dsRNA binding σ3 respectively.

Mohamed, Adil; Konda, Prathyusha; Eaton, Heather E; Gujar, Shashi; Smiley, James R; Shmulevitz, Maya.

PLoS Pathog ; 16(9): e1008803, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32956403

5.

Metabolite profiling reveals a connection between aldehyde dehydrogenase 1A3 and GABA metabolism in breast cancer metastasis.

Dahn, Margaret L; Walsh, Hayley R; Dean, Cheryl A; Giacomantonio, Michael A; Fernando, Wasundara; Murphy, J Patrick; Walker, Olivia L; Wasson, Marie-Claire D; Gujar, Shashi; Pinto, Devanand M; Marcato, Paola.

Metabolomics ; 18(1): 9, 2022 01 06.

Artículo en Inglés | MEDLINE | ID: mdl-34989902

6.

Single Amino Acid Differences between Closely Related Reovirus T3D Lab Strains Alter Oncolytic Potency In Vitro and In Vivo.

Mohamed, Adil; Clements, Derek R; Gujar, Shashi A; Lee, Patrick W; Smiley, James R; Shmulevitz, Maya.

J Virol ; 94(4)2020 01 31.

Artículo en Inglés | MEDLINE | ID: mdl-31748391

7.

Antitumor Benefits of Antiviral Immunity: An Underappreciated Aspect of Oncolytic Virotherapies.

Gujar, Shashi; Pol, Jonathan G; Kim, Youra; Lee, Patrick W; Kroemer, Guido.

Trends Immunol ; 39(3): 209-221, 2018 03.

Artículo en Inglés | MEDLINE | ID: mdl-29275092

8.

Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433.

Monro, Susan; Colón, Katsuya L; Yin, Huimin; Roque, John; Konda, Prathyusha; Gujar, Shashi; Thummel, Randolph P; Lilge, Lothar; Cameron, Colin G; McFarland, Sherri A.

Chem Rev ; 119(2): 797-828, 2019 01 23.

Artículo en Inglés | MEDLINE | ID: mdl-30295467

9.

Targeted Metabolic Reprogramming to Improve the Efficacy of Oncolytic Virus Therapy.

Kennedy, Barry E; Sadek, Maryanne; Gujar, Shashi A.

Mol Ther ; 28(6): 1417-1421, 2020 06 03.

Artículo en Inglés | MEDLINE | ID: mdl-32243836

10.

Quantitative Proteome Responses to Oncolytic Reovirus in GM-CSF- and M-CSF-Differentiated Bone Marrow-Derived Cells.

Giacomantonio, Michael A; Sterea, Andra M; Kim, Youra; Paulo, Joao A; Clements, Derek R; Kennedy, Barry E; Bydoun, Moamen J; Shi, Ge; Waisman, David M; Gygi, Steven P; Giacomantonio, Carman A; Murphy, J Patrick; Gujar, Shashi.

J Proteome Res ; 19(2): 708-718, 2020 02 07.

Artículo en Inglés | MEDLINE | ID: mdl-31884793

11.

Improving MHC-I Ligand Identifications from LC-MS/MS Data by Incorporating Allelic Peptide Motifs.

Konda, Prathyusha; Murphy, J Patrick; Gujar, Shashi.

Proteomics ; 19(5): e1800458, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30710433

12.

Therapy-Induced MHC I Ligands Shape Neo-Antitumor CD8 T Cell Responses during Oncolytic Virus-Based Cancer Immunotherapy.

Murphy, J Patrick; Kim, Youra; Clements, Derek R; Konda, Prathyusha; Schuster, Heiko; Kowalewski, Daniel J; Paulo, Joao A; Cohen, Alejandro M; Stevanovic, Stefan; Gygi, Steven P; Gujar, Shashi.

J Proteome Res ; 18(6): 2666-2675, 2019 06 07.

Artículo en Inglés | MEDLINE | ID: mdl-31095916

13.

TRPM2 channel-mediated regulation of autophagy maintains mitochondrial function and promotes gastric cancer cell survival via the JNK-signaling pathway.

Almasi, Shekoufeh; Kennedy, Barry E; El-Aghil, Mariam; Sterea, Andra M; Gujar, Shashi; Partida-Sánchez, Santiago; El Hiani, Yassine.

J Biol Chem ; 293(10): 3637-3650, 2018 03 09.

Artículo en Inglés | MEDLINE | ID: mdl-29343514

14.

Multiplexed Relative Quantitation with Isobaric Tagging Mass Spectrometry Reveals Class I Major Histocompatibility Complex Ligand Dynamics in Response to Doxorubicin.

Murphy, J Patrick; Yu, Qijia; Konda, Prathyusha; Paulo, Joao A; Jedrychowski, Mark P; Kowalewski, Daniel J; Schuster, Heiko; Kim, Youra; Clements, Derek; Jain, Aditya; Stevanovic, Stefan; Gygi, Steven P; Mancias, Joseph D; Gujar, Shashi.

Anal Chem ; 91(8): 5106-5115, 2019 04 16.

Artículo en Inglés | MEDLINE | ID: mdl-30779550

15.

TRPM2 Silencing Causes G2/M Arrest and Apoptosis in Lung Cancer Cells via Increasing Intracellular ROS and RNS Levels and Activating the JNK Pathway.

Almasi, Shekoufeh; Long, Clara Yu; Sterea, Andra; Clements, Derek Richard; Gujar, Shashi; El Hiani, Yassine.

Cell Physiol Biochem ; 52(4): 742-757, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-30933439

16.

Epigenetic Silencing of TAP1 in Aldefluor⁺ Breast Cancer Stem Cells Contributes to Their Enhanced Immune Evasion.

Sultan, Mohammad; Vidovic, Dejan; Paine, Arianne S; Huynh, Thomas T; Coyle, Krysta M; Thomas, Margaret L; Cruickshank, Brianne M; Dean, Cheryl A; Clements, Derek R; Kim, Youra; Lee, Kristen; Gujar, Shashi A; Weaver, Ian C G; Marcato, Paola.

Stem Cells ; 36(5): 641-654, 2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29341428

17.

RTN4 Knockdown Dysregulates the AKT Pathway, Destabilizes the Cytoskeleton, and Enhances Paclitaxel-Induced Cytotoxicity in Cancers.

Pathak, Gopal P; Shah, Rashmi; Kennedy, Barry E; Murphy, J Patrick; Clements, Derek; Konda, Prathyusha; Giacomantonio, Michael; Xu, Zhaolin; Schlaepfer, Isabel R; Gujar, Shashi.

Mol Ther ; 26(8): 2019-2033, 2018 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-30078441

18.

MHC-I Ligand Discovery Using Targeted Database Searches of Mass Spectrometry Data: Implications for T-Cell Immunotherapies.

Murphy, J Patrick; Konda, Prathyusha; Kowalewski, Daniel J; Schuster, Heiko; Clements, Derek; Kim, Youra; Cohen, Alejandro M; Sharif, Tanveer; Nielsen, Morten; Stevanovic, Stefan; Lee, Patrick W; Gujar, Shashi.

J Proteome Res ; 16(4): 1806-1816, 2017 04 07.

Artículo en Inglés | MEDLINE | ID: mdl-28244318

19.

Quantitative Temporal in Vivo Proteomics Deciphers the Transition of Virus-Driven Myeloid Cells into M2 Macrophages.

Clements, Derek R; Murphy, John Patrick; Sterea, Andra; Kennedy, Barry E; Kim, Youra; Helson, Erin; Almasi, Shekoufeh; Holay, Namit; Konda, Prathyusha; Paulo, Joao A; Sharif, Tanveer; Lee, Patrick W; Weekes, Michael P; Gygi, Steven P; Gujar, Shashi.

J Proteome Res ; 16(9): 3391-3406, 2017 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-28768414

20.

Hide-and-seek: the interplay between cancer stem cells and the immune system.

Sultan, Mohammad; Coyle, Krysta Mila; Vidovic, Dejan; Thomas, Margaret Lois; Gujar, Shashi; Marcato, Paola.

Carcinogenesis ; 38(2): 107-118, 2017 02 01.

Artículo en Inglés | MEDLINE | ID: mdl-27866156

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