Corrigendum to "Desflurane Attenuates Ventilator-Induced Lung Injury in Rats with Acute Respiratory Distress Syndrome".

[This corrects the article DOI: 10.1155/2018/7507314.].

[Relationship of population quality and nitrogen fertilizer utilization characteristics of direct seeding rice under water-nitrogen interaction]. / æ°´æ°®äº’ä½œä¸‹ç›´æ’­ç¨»ç¾¤ä½“è´¨é‡ä¸Žæ°®ç´ åˆ©ç”¨ç‰¹å¾çš„å ³ç³».

Understanding population quality and nitrogen utilization characteristics of direct seeding rice under water-nitrogen interaction could provide theoretical and practical basis for high yield and ample production of direct seeding rice. Hybrid rice F You 498 was used as the material. Three irrigation methods were set in this study: flooding irrigation (W1), dry-wet alternate irrigation (W2) and drying irrigation (W3), with different ratio of base fertilizer: tiller fertilizer: panicle fertilizer at 5:3:2 (N1), 3:3:4 (N2), 3:1:6 (N3), respectively. No nitrogen application (N0) was set as the control. We investigated the effects of water-nitrogen interaction on population quality and nitrogen utilization characteristics of direct seeding rice, with the aim to clarify the relationship between population quality construction, nitrogen utilization characteristics and yield of direct seeding rice. The results showed that irrigation and N rate significantly interacted to affect dry matter accumulation, rice harvest index, heading high-efficiency leaf (the upper three leaves) dry weight, light transmittance rate at maturity stage, total nitrogen accumulation (TNA), apparent nitrogen use efficiency (ANE), nitrogen partial factor productivity (NPFP), nitrogen physiology efficiency, and rice yield. Taking population quality, yield and N fertilizer utilization characteristics into consideration, suitable panicle N-fertilizer under each irrigation mode was 20%-40% (N1-N2). Panicle N-fertilizer reached 60% (N3) and W3 treatment would significantly reduce population quality, yield, nitrogen agronomy efficiency (NAE), NPFP of direct seeding rice. Yield and nitrogen utilization characteristics of direct seeding rice were significantly correlated with effective panicles, dry matter accumulation at maturity stage, other leaf (except the upper three leaves) dry weight reduction, total leaf dry weight reduction, and middle part and basel part light-receiving rate under water-nitrogen interaction. The dry-wet alternative (W2) treatment could increase the rate of production til-lers, dry matter accumulation, rice harvest index, TNA, NAE and rice yield. W2 combined with N2 could improve population quality of direct seeding rice and realized the coordination and unification of high yield and efficient utilization of nitrogen, which is the best combination in this experiment.

Endothelial progenitor cells attenuate the lung ischemia/reperfusion injury following lung transplantation via the endothelial nitric oxide synthase pathway.

OBJECTIVE: Endothelial progenitor cells (EPCs) can improve endothelial integrity. This study aimed to examine the effects and the mechanism of EPCs on lung ischemia-reperfusion injury (LIRI). METHODS: Wistar rats were randomized into the sham or the left lung transplantation group. The recipients were randomized and treated with vehicle as the LIRI group, with EPC as the EPC group, or with N5-(1-iminoethyl)-l-ornithine-pretreated EPC as the EPC/L group (n = 8 per group). The ratios of arterial oxygen partial pressure to fractional inspiratory oxygen were measured. The lung wet-to-dry weight ratios, protein levels, and injury, as well as the levels of plasma cytokines, were examined. The levels of endothelin (ET)-1, endothelial nitric oxide synthase (eNOS), phosphorylated eNOS, inducible NOS, phosphorylated myosin light chain, nuclear factor-κBp65, Bax, Bcl-2, cleaved caspase-3, and myeloperoxidase in the graft lungs were detected. RESULTS: Compared with the LIRI group, EPC treatment significantly increased the ratios of arterial oxygen partial pressure to fractional inspiratory oxygen and decreased the lung wet-to-dry weight ratios and protein levels in the grafts, accompanied by increasing eNOS expression and phosphorylation, but decreasing endothelin-1, inducible NOS, phosphorylated nuclear factor-kBp65, phosphorylated myosin light chain expression, and myeloperoxidase activity. EPCs reduced lung tissue damage and apoptosis associated with decreased levels of Bax and cleaved caspase-3 expression, but increased Bcl-2 expression. EPC treatment significantly reduced the levels of serum proinflammatory factors, but elevated levels of interleukin-10. In contrast, the protective effect of EPCs were mitigated and abrogated by N5-(1-iminoethyl)-l-ornithine pretreatment. CONCLUSIONS: Data indicated that EPC ameliorated LIRI by increasing eNOS expression.

Desflurane Attenuates Ventilator-Induced Lung Injury in Rats with Acute Respiratory Distress Syndrome.

Ventilator-induced lung injury aggravates the existing lung injury. This study investigated the effect of desflurane on VILI in a rat model of acute respiratory distress syndrome. Forty-eight rats were randomized into a sham (S) group, control (C) group, lipopolysaccharide/ventilation (LV) group, lipopolysaccharide/ventilation/desflurane (LVD) group, or lipopolysaccharide/low ventilation with and without desflurane (LLV and LLVD) groups. Rats in the S group received anesthesia only. Rats in the LV and LVD groups received lipopolysaccharide and were ventilated with a high tidal volume. Rats in LLV and LLVD groups were treated as the LV and LVD groups and ventilated with a low tidal volume. PaO2/FiO2, lung wet-to-dry weight ratios, concentrations of inflammatory factors in serum and BALF, histopathologic analysis of lung tissue, and levels of nuclear factor- (NF-) κB protein in lung tissue were investigated. PaO2/FiO2 was significantly increased by desflurane. Total cell count, macrophages, and neutrophils in BALF and proinflammatory factors in BALF and serum were significantly decreased by desflurane, while IL-10 was increased. The histopathological changes and levels of NF-κB protein in lung tissue were decreased by desflurane. The results indicated that desflurane ameliorated VILI in a rat model of acute respiratory distress syndrome.