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Arch Dis Child Fetal Neonatal Ed ; 107(2): 121-125, 2022 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-33658282

RESUMEN

Antenatal corticosteroids undoubtedly save many lives and improve the quality of many others. However, the currently accepted dosage schedule has been in place since 1972, and recent studies have suggested that beneficial effects may be seen with less. Most but not all studies of long-term outcome show no adverse effects. The use of antenatal corticosteroids in women with COVID-19 raises important questions regarding potential risks and benefits. However, currently, most authorities recommend continuing according to published guidelines. With regard to postnatal corticosteroids, alternatives to systemic dexamethasone, the somewhat tainted standard of care, show promise in preventing bronchopulmonary dysplasia without adverse effects. Systemic hydrocortisone and inhaled corticosteroids are of note. The mixture of surfactant and corticosteroids deserves particular attention in the coming years.


Asunto(s)
Corticoesteroides/uso terapéutico , COVID-19/epidemiología , Recien Nacido Prematuro , Efectos Tardíos de la Exposición Prenatal/epidemiología , Corticoesteroides/administración & dosificación , Corticoesteroides/efectos adversos , Displasia Broncopulmonar/tratamiento farmacológico , Relación Dosis-Respuesta a Droga , Esquema de Medicación , Femenino , Edad Gestacional , Humanos , Recién Nacido , Embarazo , Complicaciones Infecciosas del Embarazo/tratamiento farmacológico , Nacimiento Prematuro/prevención & control , Surfactantes Pulmonares/uso terapéutico , SARS-CoV-2 , Tratamiento Farmacológico de COVID-19
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