1.
J Org Chem
; 2024 Jun 28.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38940722
RESUMEN
Herein, a photocatalytic umpolung strategy for reductive carboxylation of imines for the synthesis of α-amino acids was disclosed. Carbon dioxide radical anion (CO2â¢-) generated from formate is the key single electron reductant in the reactions. An unprecedentedly broad substrate scope of imines with excellent reaction yields was obtained with carbon dioxide (CO2) and formate salt as carbon sources.