Electricity Theft Detection in Smart Grids Using a Hybrid BiGRU-BiLSTM Model with Feature Engineering-Based Preprocessing.

In this paper, a defused decision boundary which renders misclassification issues due to the presence of cross-pairs is investigated. Cross-pairs retain cumulative attributes of both classes and misguide the classifier due to the defused data samples' nature. To tackle the problem of the defused data, a Tomek Links technique targets the cross-pair majority class and is removed, which results in an affine-segregated decision boundary. In order to cope with a Theft Case scenario, theft data is ascertained and synthesized randomly by using six theft data variants. Theft data variants are benign class appertaining data samples which are modified and manipulated to synthesize malicious samples. Furthermore, a K-means minority oversampling technique is used to tackle the class imbalance issue. In addition, to enhance the detection of the classifier, abstract features are engineered using a stochastic feature engineering mechanism. Moreover, to carry out affine training of the model, balanced data are inputted in order to mitigate class imbalance issues. An integrated hybrid model consisting of Bi-Directional Gated Recurrent Units and Bi-Directional Long-Term Short-Term Memory classifies the consumers, efficiently. Afterwards, robustness performance of the model is verified using an attack vector which is subjected to intervene in the model's efficiency and integrity. However, the proposed model performs efficiently on such unseen attack vectors.

Real time anatomical landmarks and abnormalities detection in gastrointestinal tract.

Gastrointestinal (GI) endoscopy is an active research field due to the lethal cancer diseases in the GI tract. Cancer treatments result better if diagnosed early and it increases the survival chances. There is a high miss rate in the detection of the abnormalities in the GI tract during endoscopy or colonoscopy due to the lack of attentiveness, tiring procedures, or the lack of required training. The procedure of the detection can be automated to the reduction of the risks by identifying and flagging the suspicious frames. A suspicious frame may have some of the abnormality or the information about anatomical landmark in the frame. The frame then can be analysed for the anatomical landmarks and the abnormalities for the detection of disease. In this research, a real-time endoscopic abnormalities detection system is presented that detects the abnormalities and the landmarks. The proposed system is based on a combination of handcrafted and deep features. Deep features are extracted from lightweight MobileNet convolutional neural network (CNN) architecture. There are some of the classes with a small inter-class difference and a higher intra-class differences, for such classes the same detection threshold is unable to distinguish. The threshold of such classes is learned from the training data using genetic algorithm. The system is evaluated on various benchmark datasets and resulted in an accuracy of 0.99 with the F1-score of 0.91 and Matthews correlation coefficient (MCC) of 0.91 on Kvasir datasets and F1-score of 0.93 on the dataset of DowPK. The system detects abnormalities in real-time with the detection speed of 41 frames per second.

Variants of Chaotic Grey Wolf Heuristic for Robust Identification of Control Autoregressive Model.

In this article, a chaotic computing paradigm is investigated for the parameter estimation of the autoregressive exogenous (ARX) model by exploiting the optimization knacks of an improved chaotic grey wolf optimizer (ICGWO). The identification problem is formulated by defining a mean square error-based fitness function between true and estimated responses of the ARX system. The decision parameters of the ARX model are calculated by ICGWO for various populations, generations, and noise levels. The comparative performance analyses with standard counterparts indicate the worth of the ICGWO for ARX model identification, while the statistical analyses endorse the efficacy of the proposed chaotic scheme in terms of accuracy, robustness, and reliability.

A comprehensive analysis of classification methods in gastrointestinal endoscopy imaging.

Gastrointestinal (GI) endoscopy has been an active field of research motivated by the large number of highly lethal GI cancers. Early GI cancer precursors are often missed during the endoscopic surveillance. The high missed rate of such abnormalities during endoscopy is thus a critical bottleneck. Lack of attentiveness due to tiring procedures, and requirement of training are few contributing factors. An automatic GI disease classification system can help reduce such risks by flagging suspicious frames and lesions. GI endoscopy consists of several multi-organ surveillance, therefore, there is need to develop methods that can generalize to various endoscopic findings. In this realm, we present a comprehensive analysis of the Medico GI challenges: Medical Multimedia Task at MediaEval 2017, Medico Multimedia Task at MediaEval 2018, and BioMedia ACM MM Grand Challenge 2019. These challenges are initiative to set-up a benchmark for different computer vision methods applied to the multi-class endoscopic images and promote to build new approaches that could reliably be used in clinics. We report the performance of 21 participating teams over a period of three consecutive years and provide a detailed analysis of the methods used by the participants, highlighting the challenges and shortcomings of the current approaches and dissect their credibility for the use in clinical settings. Our analysis revealed that the participants achieved an improvement on maximum Mathew correlation coefficient (MCC) from 82.68% in 2017 to 93.98% in 2018 and 95.20% in 2019 challenges, and a significant increase in computational speed over consecutive years.

In silico Screening for Identification of Novel Anti-malarial Inhibitors by Molecular Docking, Pharmacophore Modeling and Virtual Screening.

OBJECTIVE: Drug resistance from affordable drugs has increased the number of deaths from malaria globally. This problem has raised the requirement to design new drugs against multidrug-resistant Plasmodium falciparum parasite. METHODS: In the current project, we have focused on four important proteins of Plasmodium falciparum and used them as receptors against a dataset of four anti-malarial drugs. In silico analysis of these receptors and ligand dataset was carried out using Autodock 4.2. A pharmacophore model was also established using Ligandscout. RESULTS: Analysis of docking experiments showed that all ligands bind efficiently to four proteins of Plasmodium falciparum. We have used ligand-based pharmacophore modeling and developed a pharmacophore model that has three hydrophobic regions, two aromatic rings, one hydrogen acceptor and one hydrogen donor. Using this pharmacophore model, we have screened a library of 50,000 compounds. The compounds that shared features of our pharmacophore model and exhibited interactions with the four proteins of our receptors dataset are short-listed. CONCLUSION: As there is a need of more anti-malarial drugs, therefore, this research will be helpful in identifying novel anti-malarial drugs that exhibited bindings with four important proteins of Plasmodium falciparum. The hits obtained in this study can be considered as useful leads in anti-malarial drug discovery.