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1.

Autologous HSCT with novel agent-based induction and consolidation followed by lenalidomide maintenance for untreated multiple myeloma.

Mori, Yasuo; Takizawa, Jun; Katsuoka, Yuna; Takezako, Naoki; Nagafuji, Koji; Handa, Hiroshi; Kuroda, Junya; Sunami, Kazutaka; Kamimura, Tomohiko; Ogawa, Ryosuke; Kikushige, Yoshikane; Harada, Mine; Akashi, Koichi; Miyamoto, Toshihiro.

Cancer Sci ; 2024 Mar 18.

Artículo en Inglés | MEDLINE | ID: mdl-38498976

2.

GPAM mediated lysophosphatidic acid synthesis regulates mitochondrial dynamics in acute myeloid leukemia.

Irifune, Hidetoshi; Kochi, Yu; Miyamoto, Toshihiro; Sakoda, Teppei; Kato, Koji; Kunisaki, Yuya; Akashi, Koichi; Kikushige, Yoshikane.

Cancer Sci ; 114(8): 3247-3258, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-37197765

3.

RHAMM marks proliferative subpopulation of human colorectal cancer stem cells.

Nakano, Michitaka; Taguchi, Ryosuke; Kikushige, Yoshikane; Isobe, Taichi; Miyawaki, Kohta; Mizuno, Shinichi; Tsuruta, Nobuhiro; Hanamura, Fumiyasu; Yamaguchi, Kyoko; Yamauchi, Takuji; Ariyama, Hiroshi; Kusaba, Hitoshi; Nakamura, Masafumi; Maeda, Takahiro; Kuo, Calvin J; Baba, Eishi; Akashi, Koichi.

Cancer Sci ; 114(7): 2895-2906, 2023 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-36945114

4.

[TIM-3 signaling hijacks the canonical Wnt/ß-catenin pathway to maintain cancer stemness in human acute myeloid leukemia].

Sakoda, Teppei; Kikushige, Yoshikane.

Rinsho Ketsueki ; 64(6): 547-552, 2023.

Artículo en Japonés | MEDLINE | ID: mdl-37407480

5.

A human SIRPA knock-in xenograft mouse model to study human hematopoietic and cancer stem cells.

Jinnouchi, Fumiaki; Yamauchi, Takuji; Yurino, Ayano; Nunomura, Takuya; Nakano, Michitaka; Iwamoto, Chika; Obara, Teppei; Miyawaki, Kohta; Kikushige, Yoshikane; Kato, Koji; Maeda, Takahiro; Miyamoto, Toshihiro; Baba, Eishi; Akashi, Koichi; Takenaka, Katsuto.

Blood ; 135(19): 1661-1672, 2020 05 07.

Artículo en Inglés | MEDLINE | ID: mdl-32206775

6.

Aromatase is a novel neosubstrate of cereblon responsible for immunomodulatory drug-induced thrombocytopenia.

Tochigi, Taro; Miyamoto, Toshihiro; Hatakeyama, Kiwamu; Sakoda, Teppei; Ishihara, Daisuke; Irifune, Hidetoshi; Shima, Takahiro; Kato, Koji; Maeda, Takahiro; Ito, Takumi; Handa, Hiroshi; Akashi, Koichi; Kikushige, Yoshikane.

Blood ; 135(24): 2146-2158, 2020 06 11.

Artículo en Inglés | MEDLINE | ID: mdl-32219443

7.

TIM-3 in normal and malignant hematopoiesis: Structure, function, and signaling pathways.

Kikushige, Yoshikane.

Cancer Sci ; 112(9): 3419-3426, 2021 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-34159709

8.

Tyrosine kinase inhibitors induce alternative spliced BCR-ABL^Ins35bp variant via inhibition of RNA polymerase II on genomic BCR-ABL.

Yuda, Junichiro; Odawara, Jun; Minami, Mariko; Muta, Tsuyoshi; Kohno, Kentaro; Tanimoto, Kazuki; Eto, Tetsuya; Shima, Takahiro; Kikushige, Yoshikane; Kato, Koji; Takenaka, Katsuto; Iwasaki, Hiromi; Minami, Yosuke; Ohkawa, Yasuyuki; Akashi, Koichi; Miyamoto, Toshihiro.

Cancer Sci ; 111(7): 2361-2373, 2020 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-32314454

9.

[Cytotoxic chemotherapy for AML in adults].

Miyamoto, Toshihiro; Kikushige, Yoshikane.

Rinsho Ketsueki ; 61(9): 1138-1149, 2020.

Artículo en Japonés | MEDLINE | ID: mdl-33162509

10.

Identification of unipotent megakaryocyte progenitors in human hematopoiesis.

Miyawaki, Kohta; Iwasaki, Hiromi; Jiromaru, Takashi; Kusumoto, Hirotake; Yurino, Ayano; Sugio, Takeshi; Uehara, Yasufumi; Odawara, Jun; Daitoku, Shinya; Kunisaki, Yuya; Mori, Yasuo; Arinobu, Yojiro; Tsuzuki, Hirofumi; Kikushige, Yoshikane; Iino, Tadafumi; Kato, Koji; Takenaka, Katsuto; Miyamoto, Toshihiro; Maeda, Takahiro; Akashi, Koichi.

Blood ; 129(25): 3332-3343, 2017 06 22.

Artículo en Inglés | MEDLINE | ID: mdl-28336526

11.

Human Herpes Virus-6-Associated Encephalitis/Myelitis Mimicking Calcineurin Inhibitor-Induced Pain Syndrome in Allogeneic Stem Cell Transplantation Recipients.

Yoshimoto, Goichi; Mori, Yasuo; Kato, Koji; Shima, Takahiro; Miyawaki, Kohta; Kikushige, Yoshikane; Kamezaki, Kenjiro; Numata, Akihiko; Maeda, Takahiro; Takenaka, Katsuto; Iwasaki, Hiromi; Teshima, Takanori; Akashi, Koichi; Miyamoto, Toshihiro.

Biol Blood Marrow Transplant ; 24(12): 2540-2548, 2018 12.

Artículo en Inglés | MEDLINE | ID: mdl-30026111

12.

Progress in the leukemic stem cell study and a novel therapeutic approach targeting leukemic stem cells.

Kikushige, Yoshikane; Miyamoto, Toshihiro; Akashi, Koichi.

Rinsho Ketsueki ; 58(10): 1838-1843, 2017.

Artículo en Japonés | MEDLINE | ID: mdl-28978822

13.

Frontline treatment of AML in adults.

Miyamoto, Toshihiro; Kikushige, Yoshikane; Yoshimoto, And Goichi.

Rinsho Ketsueki ; 58(10): 1884-1894, 2017.

Artículo en Japonés | MEDLINE | ID: mdl-28978829

14.

CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: redefinition of murine common myeloid progenitor.

Miyawaki, Kohta; Arinobu, Yojiro; Iwasaki, Hiromi; Kohno, Kentaro; Tsuzuki, Hirofumi; Iino, Tadafumi; Shima, Takahiro; Kikushige, Yoshikane; Takenaka, Katsuto; Miyamoto, Toshihiro; Akashi, Koichi.

Stem Cells ; 33(3): 976-87, 2015 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-25446279

15.

[A TIM-3/galectin-9 autocrine stimulatory loop drives self-renewal of human myeloid leukemia stem cells and leukemia progression].

Kikushige, Yoshikane.

Rinsho Ketsueki ; 57(4): 412-6, 2016 Apr.

Artículo en Japonés | MEDLINE | ID: mdl-27169443

16.

Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment.

Yamauchi, Takuji; Takenaka, Katsuto; Urata, Shingo; Shima, Takahiro; Kikushige, Yoshikane; Tokuyama, Takahito; Iwamoto, Chika; Nishihara, Mariko; Iwasaki, Hiromi; Miyamoto, Toshihiro; Honma, Nakayuki; Nakao, Miki; Matozaki, Takashi; Akashi, Koichi.

Blood ; 121(8): 1316-25, 2013 Feb 21.

Artículo en Inglés | MEDLINE | ID: mdl-23293079

17.

Quantitation of hematogones at the time of engraftment is a useful prognostic indicator in allogeneic hematopoietic stem cell transplantation.

Shima, Takahiro; Miyamoto, Toshihiro; Kikushige, Yoshikane; Mori, Yasuo; Kamezaki, Kenjiro; Takase, Ken; Henzan, Hideho; Numata, Akihiko; Ito, Yoshikiyo; Takenaka, Katsuto; Iwasaki, Hiromi; Kamimura, Tomohiko; Eto, Tetsuya; Nagafuji, Koji; Teshima, Takanori; Kato, Koji; Akashi, Koichi.

Blood ; 121(5): 840-8, 2013 Jan 31.

Artículo en Inglés | MEDLINE | ID: mdl-23233661

18.

Identification of TIM-3 as a Leukemic Stem Cell Surface Molecule in Primary Acute Myeloid Leukemia.

Kikushige, Yoshikane; Miyamoto, Toshihiro.

Oncology ; 89 Suppl 1: 28-32, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-26551150

19.

[Molecular targeted therapy for leukemic stem cells].

Kikushige, Yoshikane.

Nihon Rinsho ; 73(5): 811-5, 2015 May.

Artículo en Japonés | MEDLINE | ID: mdl-25985636

20.

Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis.

Kuriyama, Takuro; Takenaka, Katsuto; Kohno, Kentaro; Yamauchi, Takuji; Daitoku, Shinya; Yoshimoto, Goichi; Kikushige, Yoshikane; Kishimoto, Junji; Abe, Yasunobu; Harada, Naoki; Miyamoto, Toshihiro; Iwasaki, Hiromi; Teshima, Takanori; Akashi, Koichi.

Blood ; 120(19): 4058-67, 2012 Nov 08.

Artículo en Inglés | MEDLINE | ID: mdl-22990013

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Autologous HSCT with novel agent-based induction and consolidation followed by lenalidomide maintenance for untreated multiple myeloma.

GPAM mediated lysophosphatidic acid synthesis regulates mitochondrial dynamics in acute myeloid leukemia.

RHAMM marks proliferative subpopulation of human colorectal cancer stem cells.

[TIM-3 signaling hijacks the canonical Wnt/ß-catenin pathway to maintain cancer stemness in human acute myeloid leukemia].

A human SIRPA knock-in xenograft mouse model to study human hematopoietic and cancer stem cells.

Aromatase is a novel neosubstrate of cereblon responsible for immunomodulatory drug-induced thrombocytopenia.

TIM-3 in normal and malignant hematopoiesis: Structure, function, and signaling pathways.

Tyrosine kinase inhibitors induce alternative spliced BCR-ABL^Ins35bp variant via inhibition of RNA polymerase II on genomic BCR-ABL.

[Cytotoxic chemotherapy for AML in adults].

Identification of unipotent megakaryocyte progenitors in human hematopoiesis.

Human Herpes Virus-6-Associated Encephalitis/Myelitis Mimicking Calcineurin Inhibitor-Induced Pain Syndrome in Allogeneic Stem Cell Transplantation Recipients.

Progress in the leukemic stem cell study and a novel therapeutic approach targeting leukemic stem cells.

Frontline treatment of AML in adults.

CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: redefinition of murine common myeloid progenitor.

[A TIM-3/galectin-9 autocrine stimulatory loop drives self-renewal of human myeloid leukemia stem cells and leukemia progression].

Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment.

Quantitation of hematogones at the time of engraftment is a useful prognostic indicator in allogeneic hematopoietic stem cell transplantation.

Identification of TIM-3 as a Leukemic Stem Cell Surface Molecule in Primary Acute Myeloid Leukemia.

[Molecular targeted therapy for leukemic stem cells].

Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis.