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1.

Ceramide as an endothelial cell surface receptor and a lung-specific lipid vascular target for circulating ligands.

Staquicini, Daniela I; Cardó-Vila, Marina; Rotolo, Jimmy A; Staquicini, Fernanda I; Tang, Fenny H F; Smith, Tracey L; Ganju, Aditya; Schiavone, Carmine; Dogra, Prashant; Wang, Zhihui; Cristini, Vittorio; Giordano, Ricardo J; Ozawa, Michael G; Driessen, Wouter H P; Proneth, Bettina; Souza, Glauco R; Brinker, Lina M; Noureddine, Achraf; Snider, Ashley J; Canals, Daniel; Gelovani, Juri G; Petrache, Irina; Tuder, Rubin M; Obeid, Lina M; Hannun, Yusuf A; Kolesnick, Richard N; Brinker, C Jeffrey; Pasqualini, Renata; Arap, Wadih.

Proc Natl Acad Sci U S A ; 120(34): e2220269120, 2023 08 22.

Artículo en Inglés | MEDLINE | ID: mdl-37579172

2.

Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis.

Wang, Jue; Keshava, Shiva; Das, Kaushik; Kolesnick, Richard; Jiang, Xian-Cheng; Pendurthi, Usha R; Rao, L Vijaya Mohan.

Arterioscler Thromb Vasc Biol ; 43(1): 64-78, 2023 01.

Artículo en Inglés | MEDLINE | ID: mdl-36412194

3.

Acid Sphingomyelinase-Ceramide Induced Vascular Injury Determines Colorectal Cancer Stem Cell Fate.

Li, Christy; Klingler, Stefan; Bodo, Sahra; Cheng, Jin; Pan, Yan; Adileh, Mohammed; Martin, Maria Laura; Fuller, John; Feldman, Regina; Michel, Adam; Zhang, Zhigang; Fuks, Zvi; Kolesnick, Richard.

Cell Physiol Biochem ; 56(4): 436-448, 2022 Aug 31.

Artículo en Inglés | MEDLINE | ID: mdl-36037065

4.

Acid sphingomyelinase deactivation post-ischemia promotes brain angiogenesis and remodeling by small extracellular vesicles.

Mohamud Yusuf, Ayan; Hagemann, Nina; Zhang, Xiaoni; Zafar, Maria; Hussner, Tanja; Bromkamp, Carolin; Martiny, Carlotta; Tertel, Tobias; Börger, Verena; Schumacher, Fabian; Solari, Fiorella A; Hasenberg, Mike; Kleinschnitz, Christoph; Doeppner, Thorsten R; Kleuser, Burkhard; Sickmann, Albert; Gunzer, Matthias; Giebel, Bernd; Kolesnick, Richard; Gulbins, Erich; Hermann, Dirk M.

Basic Res Cardiol ; 117(1): 43, 2022 12.

Artículo en Inglés | MEDLINE | ID: mdl-36038749

5.

Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease.

Hanash, Alan M; Dudakov, Jarrod A; Hua, Guoqiang; O'Connor, Margaret H; Young, Lauren F; Singer, Natalie V; West, Mallory L; Jenq, Robert R; Holland, Amanda M; Kappel, Lucy W; Ghosh, Arnab; Tsai, Jennifer J; Rao, Uttam K; Yim, Nury L; Smith, Odette M; Velardi, Enrico; Hawryluk, Elena B; Murphy, George F; Liu, Chen; Fouser, Lynette A; Kolesnick, Richard; Blazar, Bruce R; van den Brink, Marcel R M.

Immunity ; 37(2): 339-50, 2012 Aug 24.

Artículo en Inglés | MEDLINE | ID: mdl-22921121

6.

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration.

Lindemans, Caroline A; Calafiore, Marco; Mertelsmann, Anna M; O'Connor, Margaret H; Dudakov, Jarrod A; Jenq, Robert R; Velardi, Enrico; Young, Lauren F; Smith, Odette M; Lawrence, Gillian; Ivanov, Juliet A; Fu, Ya-Yuan; Takashima, Shuichiro; Hua, Guoqiang; Martin, Maria L; O'Rourke, Kevin P; Lo, Yuan-Hung; Mokry, Michal; Romera-Hernandez, Monica; Cupedo, Tom; Dow, Lukas; Nieuwenhuis, Edward E; Shroyer, Noah F; Liu, Chen; Kolesnick, Richard; van den Brink, Marcel R M; Hanash, Alan M.

Nature ; 528(7583): 560-564, 2015 Dec 24.

Artículo en Inglés | MEDLINE | ID: mdl-26649819

7.

Acid-Sphingomyelinase Triggered Fluorescently Labeled Sphingomyelin Containing Liposomes in Tumor Diagnosis after Radiation-Induced Stress.

Heneweer, Carola; Peñate Medina, Tuula; Tower, Robert; Kalthoff, Holger; Kolesnick, Richard; Larson, Steven; Peñate Medina, Oula.

Int J Mol Sci ; 22(8)2021 Apr 08.

Artículo en Inglés | MEDLINE | ID: mdl-33917976

8.

Enhancement of Soft Tissue Sarcoma Response to Gemcitabine through Timed Administration of a Short-Acting Anti-Angiogenic Agent.

Cheng, Jin; Fuller, John; Feldman, Regina; Tap, William; Owa, Takashi; Fuks, Zvi; Kolesnick, Richard.

Cell Physiol Biochem ; 54(4): 707-718, 2020 Jul 29.

Artículo en Inglés | MEDLINE | ID: mdl-32722909

9.

Homozygous Smpd1 deficiency aggravates brain ischemia/ reperfusion injury by mechanisms involving polymorphonuclear neutrophils, whereas heterozygous Smpd1 deficiency protects against mild focal cerebral ischemia.

Hagemann, Nina; Mohamud Yusuf, Ayan; Martiny, Carlotta; Zhang, Xiaoni; Kleinschnitz, Christoph; Gunzer, Matthias; Kolesnick, Richard; Gulbins, Erich; Hermann, Dirk M.

Basic Res Cardiol ; 115(6): 64, 2020 10 14.

Artículo en Inglés | MEDLINE | ID: mdl-33057972

10.

Targeting acid sphingomyelinase reduces cardiac ceramide accumulation in the post-ischemic heart.

Klevstig, Martina; Ståhlman, Marcus; Lundqvist, Annika; Scharin Täng, Margareta; Fogelstrand, Per; Adiels, Martin; Andersson, Linda; Kolesnick, Richard; Jeppsson, Anders; Borén, Jan; Levin, Malin C.

J Mol Cell Cardiol ; 93: 69-72, 2016 04.

Artículo en Inglés | MEDLINE | ID: mdl-26930027

11.

Regulation of ceramide generation during macrophage apoptosis by ASMase and de novo synthesis.

Wang, Shih Wei; Hojabrpour, Payman; Zhang, Peng; Kolesnick, Richard N; Steinbrecher, Urs P; Gómez-Muñoz, Antonio; Duronio, Vincent.

Biochim Biophys Acta ; 1851(11): 1482-9, 2015 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-26253821

12.

Caenorhabditis elegans as a model to study sphingolipid signaling.

Deng, Xinzhu; Kolesnick, Richard.

Biol Chem ; 396(6-7): 767-73, 2015 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-25720116

13.

A CERTain role for ceramide in taxane-induced cell death.

Kolesnick, Richard; Altieri, Dario; Fuks, Zvi.

Cancer Cell ; 11(6): 473-5, 2007 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-17560328

14.

MicroRNA-10a enrichment in factor VIIa-released endothelial extracellular vesicles: potential mechanisms.

Das, Kaushik; Keshava, Shiva; Kolesnick, Richard; Pendurthi, Usha R; Rao, L Vijaya Mohan.

J Thromb Haemost ; 22(2): 441-454, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-37926194

15.

Diabetic retinopathy is a ceramidopathy reversible by anti-ceramide immunotherapy.

Dorweiler, Tim F; Singh, Arjun; Ganju, Aditya; Lydic, Todd A; Glazer, Louis C; Kolesnick, Richard N; Busik, Julia V.

Cell Metab ; 2024 May 03.

Artículo en Inglés | MEDLINE | ID: mdl-38718792

16.

Crypt base columnar stem cells in small intestines of mice are radioresistant.

Hua, Guoqiang; Thin, Tin Htwe; Feldman, Regina; Haimovitz-Friedman, Adriana; Clevers, Hans; Fuks, Zvi; Kolesnick, Richard.

Gastroenterology ; 143(5): 1266-1276, 2012 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-22841781

17.

Engaging the vascular component of the tumor response.

Fuks, Zvi; Kolesnick, Richard.

Cancer Cell ; 8(2): 89-91, 2005 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-16098459

18.

Using ASMase knockout mice to model human diseases.

Hua, Guoqiang; Kolesnick, Richard.

Handb Exp Pharmacol ; (216): 29-54, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-23563650

19.

Acid sphingomyelinase.

Henry, Brian; Ziobro, Regan; Becker, Katrin Anne; Kolesnick, Richard; Gulbins, Erich.

Handb Exp Pharmacol ; (215): 77-88, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-23579450

20.

Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation.

Deng, Xinzhu; Hofmann, E Randal; Villanueva, Alberto; Hobert, Oliver; Capodieci, Paola; Veach, Darren R; Yin, Xianglei; Campodonico, Luis; Glekas, Athanasios; Cordon-Cardo, Carlos; Clarkson, Bayard; Bornmann, William G; Fuks, Zvi; Hengartner, Michael O; Kolesnick, Richard.

Nat Genet ; 36(8): 906-12, 2004 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-15273685

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