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1.

EDC3 phosphorylation regulates growth and invasion through controlling P-body formation and dynamics.

Bearss, Jeremiah J; Padi, Sathish Kr; Singh, Neha; Cardo-Vila, Marina; Song, Jin H; Mouneimne, Ghassan; Fernandes, Nikita; Li, Yang; Harter, Matthew R; Gard, Jaime Mc; Cress, Anne E; Peti, Wolfgang; Nelson, Andrew Dl; Buchan, J Ross; Kraft, Andrew S; Okumura, Koichi.

EMBO Rep ; 22(4): e50835, 2021 04 07.

Artículo en Inglés | MEDLINE | ID: mdl-33586867

2.

OER-073: A multicenter phase 2 study evaluating the role of pazopanib in angiosarcoma.

Thiebaud, Julio Alvarenga; Ravi, Vinod; Litwin, Samuel; Schuetze, Scott M; Movva, Sujana; Agulnik, Mark; Kraft, Andrew S; Tetzlaff, Eric D; Somaiah, Neeta; von Mehren, Margaret.

Cancer ; 128(19): 3516-3522, 2022 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-35942596

3.

Phosphorylation of DEPDC5, a component of the GATOR1 complex, releases inhibition of mTORC1 and promotes tumor growth.

Padi, Sathish K R; Singh, Neha; Bearss, Jeremiah J; Olive, Virginie; Song, Jin H; Cardó-Vila, Marina; Kraft, Andrew S; Okumura, Koichi.

Proc Natl Acad Sci U S A ; 116(41): 20505-20510, 2019 10 08.

Artículo en Inglés | MEDLINE | ID: mdl-31548394

4.

Synthesis of 2-Oxoquinoline Derivatives as Dual Pim and mTORC Protein Kinase Inhibitors.

Gnawali, Giri R; Okumura, Koichi; Perez, Karolina; Gallagher, Rosa; Wulfkuhle, Julia; Petricoin, Emanuel F; Padi, Sathish Kumar Reddy; Bearss, Jeremiah; He, Zhiyong; Wang, Wei; Kraft, Andrew S.

Med Chem Res ; 31(7): 1154-1175, 2022 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-36389181

5.

A randomized, open-label, phase 2, multicenter trial of gemcitabine with pazopanib or gemcitabine with docetaxel in patients with advanced soft-tissue sarcoma.

Somaiah, Neeta; Van Tine, Brian Andrew; Wahlquist, Amy E; Milhem, Mohammed M; Hill, Elizabeth G; Garrett-Mayer, Elizabeth; Armeson, Kent E; Schuetze, Scott M; Meyer, Christian F; Reuben, Daniel Y; Elias, Anthony D; Read, William L; Chawla, Sant P; Kraft, Andrew S.

Cancer ; 127(6): 894-904, 2021 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-33231866

6.

SMACing down relapsed T-ALL.

Sawyer, Eric M; Kraft, Andrew S.

Blood ; 143(21): 2116-2117, 2024 May 23.

Artículo en Inglés | MEDLINE | ID: mdl-38780917

7.

"Root"ing for successful T-ALL treatment.

Padi, Sathish K R; Kraft, Andrew S.

Blood ; 137(18): 2422-2423, 2021 05 06.

Artículo en Inglés | MEDLINE | ID: mdl-33956068

8.

Metabolic dysfunction consistent with premature aging results from deletion of Pim kinases.

Din, Shabana; Konstandin, Mathias H; Johnson, Bevan; Emathinger, Jacqueline; Völkers, Mirko; Toko, Haruhiro; Collins, Brett; Ormachea, Lucy; Samse, Kaitlen; Kubli, Dieter A; De La Torre, Andrea; Kraft, Andrew S; Gustafsson, Asa B; Kelly, Daniel P; Sussman, Mark A.

Circ Res ; 115(3): 376-87, 2014 Jul 18.

Artículo en Inglés | MEDLINE | ID: mdl-24916111

9.

Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells.

An, Ningfei; Lin, Ying-Wei; Mahajan, Sandeep; Kellner, Joshua N; Wang, Yong; Li, Zihai; Kraft, Andrew S; Kang, Yubin.

Stem Cells ; 31(6): 1202-12, 2013 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-23495171

10.

The Pim protein kinases regulate energy metabolism and cell growth.

Beharry, Zanna; Mahajan, Sandeep; Zemskova, Marina; Lin, Ying-Wei; Tholanikunnel, Baby G; Xia, Zuping; Smith, Charles D; Kraft, Andrew S.

Proc Natl Acad Sci U S A ; 108(2): 528-33, 2011 Jan 11.

Artículo en Inglés | MEDLINE | ID: mdl-21187426

11.

Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial.

Schwartz, Gary K; Tap, William D; Qin, Li-Xuan; Livingston, Michael B; Undevia, Samir D; Chmielowski, Bartosz; Agulnik, Mark; Schuetze, Scott M; Reed, Damon R; Okuno, Scott H; Ludwig, Joseph A; Keedy, Vicki; Rietschel, Petra; Kraft, Andrew S; Adkins, Douglas; Van Tine, Brian A; Brockstein, Bruce; Yim, Vincent; Bitas, Christiana; Abdullah, Abdul; Antonescu, Cristina R; Condy, Mercedes; Dickson, Mark A; Vasudeva, Shyamprasad Deraje; Ho, Alan L; Doyle, L Austin; Chen, Helen X; Maki, Robert G.

Lancet Oncol ; 14(4): 371-82, 2013 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-23477833

12.

Multiple phosphorylation sites are important for RUNX1 activity in early hematopoiesis and T-cell differentiation.

Yoshimi, Mayumi; Goyama, Susumu; Kawazu, Masahito; Nakagawa, Masahiro; Ichikawa, Motoshi; Imai, Yoichi; Kumano, Keiki; Asai, Takashi; Mulloy, James C; Kraft, Andrew S; Takahashi, Tsuyoshi; Shirafuji, Naoki; Kurokawa, Mineo.

Eur J Immunol ; 42(4): 1044-50, 2012 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-22531928

13.

A phase II trial of dasatinib in patients with metastatic castration-resistant prostate cancer treated previously with chemotherapy.

Twardowski, Przemyslaw W; Beumer, Jan H; Chen, C S; Kraft, Andrew S; Chatta, Gurkamal S; Mitsuhashi, Masato; Ye, Wei; Christner, Susan M; Lilly, Michael B.

Anticancer Drugs ; 24(7): 743-53, 2013 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-23652277

14.

An XBP1s-PIM-2 positive feedback loop controls IL-15-mediated survival of natural killer cells.

Ma, Shoubao; Han, Jingjing; Li, Zhenlong; Xiao, Sai; Zhang, Jianying; Yan, Jiazhuo; Tang, Tingting; Barr, Tasha; Kraft, Andrew S; Caligiuri, Michael A; Yu, Jianhua.

Sci Immunol ; 8(81): eabn7993, 2023 03 17.

Artículo en Inglés | MEDLINE | ID: mdl-36897958

15.

PIM1 phosphorylates ABI2 to enhance actin dynamics and promote tumor invasion.

Jensen, Corbin C; Clements, Amber N; Liou, Hope; Ball, Lauren E; Bethard, Jennifer R; Langlais, Paul R; Toth, Rachel K; Chauhan, Shailender S; Casillas, Andrea L; Daulat, Sohail R; Kraft, Andrew S; Cress, Anne E; Miranti, Cindy K; Mouneimne, Ghassan; Rogers, Greg C; Warfel, Noel A.

J Cell Biol ; 222(6)2023 06 05.

Artículo en Inglés | MEDLINE | ID: mdl-37042842

16.

A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma.

Lin, Ying-Wei; Beharry, Zanna M; Hill, Elizabeth G; Song, Jin H; Wang, Wenxue; Xia, Zuping; Zhang, Zhenhua; Aplan, Peter D; Aster, Jon C; Smith, Charles D; Kraft, Andrew S.

Blood ; 115(4): 824-33, 2010 Jan 28.

Artículo en Inglés | MEDLINE | ID: mdl-19965690

17.

Regulation of Skp2 levels by the Pim-1 protein kinase.

Cen, Bo; Mahajan, Sandeep; Zemskova, Marina; Beharry, Zanna; Lin, Ying-Wei; Cramer, Scott D; Lilly, Michael B; Kraft, Andrew S.

J Biol Chem ; 285(38): 29128-37, 2010 Sep 17.

Artículo en Inglés | MEDLINE | ID: mdl-20663873

18.

Sustained response to pembrolizumab in recurrent perivascular epithelioid cell tumor with elevated expression of programmed death ligand: a case report.

McBride, Ali; Garcia, Andrew J; Sanders, Lauren J; Yiu, Kelly; Cranmer, Lee D; Kuo, Phillip H; Kay, Matthew; Kraft, Andrew S.

J Med Case Rep ; 15(1): 400, 2021 Jul 24.

Artículo en Inglés | MEDLINE | ID: mdl-34301321

19.

The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer.

Singh, Neha; Ramnarine, Varune R; Song, Jin H; Pandey, Ritu; Padi, Sathish K R; Nouri, Mannan; Olive, Virginie; Kobelev, Maxim; Okumura, Koichi; McCarthy, David; Hanna, Michelle M; Mukherjee, Piali; Sun, Belinda; Lee, Benjamin R; Parker, J Brandon; Chakravarti, Debabrata; Warfel, Noel A; Zhou, Muhan; Bearss, Jeremiah J; Gibb, Ewan A; Alshalalfa, Mohammed; Karnes, R Jefferey; Small, Eric J; Aggarwal, Rahul; Feng, Felix; Wang, Yuzhuo; Buttyan, Ralph; Zoubeidi, Amina; Rubin, Mark; Gleave, Martin; Slack, Frank J; Davicioni, Elai; Beltran, Himisha; Collins, Colin; Kraft, Andrew S.

Nat Commun ; 12(1): 7349, 2021 12 21.

Artículo en Inglés | MEDLINE | ID: mdl-34934057

20.

PIM Kinase Inhibitors Block the Growth of Primary T-cell Acute Lymphoblastic Leukemia: Resistance Pathways Identified by Network Modeling Analysis.

Lim, James T; Singh, Neha; Leuvano, Libia A; Calvert, Valerie S; Petricoin, Emanuel F; Teachey, David T; Lock, Richard B; Padi, Megha; Kraft, Andrew S; Padi, Sathish K R.

Mol Cancer Ther ; 19(9): 1809-1821, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32753387

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