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1.

Enhancer-promoter interactions are reconfigured through the formation of long-range multiway hubs as mouse ES cells exit pluripotency.

Lando, David; Ma, Xiaoyan; Cao, Yang; Jartseva, Aleksandra; Stevens, Tim J; Boucher, Wayne; Reynolds, Nicola; Montibus, Bertille; Hall, Dominic; Lackner, Andreas; Ragheb, Ramy; Leeb, Martin; Hendrich, Brian D; Laue, Ernest D.

Mol Cell ; 84(8): 1406-1421.e8, 2024 Apr 18.

Artículo en Inglés | MEDLINE | ID: mdl-38490199

2.

3D structures of individual mammalian genomes studied by single-cell Hi-C.

Stevens, Tim J; Lando, David; Basu, Srinjan; Atkinson, Liam P; Cao, Yang; Lee, Steven F; Leeb, Martin; Wohlfahrt, Kai J; Boucher, Wayne; O'Shaughnessy-Kirwan, Aoife; Cramard, Julie; Faure, Andre J; Ralser, Meryem; Blanco, Enrique; Morey, Lluis; Sansó, Miriam; Palayret, Matthieu G S; Lehner, Ben; Di Croce, Luciano; Wutz, Anton; Hendrich, Brian; Klenerman, Dave; Laue, Ernest D.

Nature ; 544(7648): 59-64, 2017 04 06.

Artículo en Inglés | MEDLINE | ID: mdl-28289288

3.

Quantification of DNA-associated proteins inside eukaryotic cells using single-molecule localization microscopy.

Etheridge, Thomas J; Boulineau, Rémi L; Herbert, Alex; Watson, Adam T; Daigaku, Yasukazu; Tucker, Jem; George, Sophie; Jönsson, Peter; Palayret, Matthieu; Lando, David; Laue, Ernest; Osborne, Mark A; Klenerman, David; Lee, Steven F; Carr, Antony M.

Nucleic Acids Res ; 42(19): e146, 2014 Oct 29.

Artículo en Inglés | MEDLINE | ID: mdl-25106872

4.

Radar observations of individual rain drops in the free atmosphere.

Schmidt, Jerome M; Flatau, Piotr J; Harasti, Paul R; Yates, Robert D; Littleton, Ricky; Pritchard, Michael S; Fischer, Jody M; Fischer, Erin J; Kohri, William J; Vetter, Jerome R; Richman, Scott; Baranowski, Dariusz B; Anderson, Mark J; Fletcher, Ed; Lando, David W.

Proc Natl Acad Sci U S A ; 109(24): 9293-8, 2012 Jun 12.

Artículo en Inglés | MEDLINE | ID: mdl-22652569

5.

A microfluidic device for the hydrodynamic immobilisation of living fission yeast cells for super-resolution imaging.

Bell, Laurence; Seshia, Ashwin; Lando, David; Laue, Ernest; Palayret, Matthieu; Lee, Steven F; Klenerman, David.

Sens Actuators B Chem ; 192: 36-41, 2014 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-25844024

6.

ALKBH1 is a histone H2A dioxygenase involved in neural differentiation.

Ougland, Rune; Lando, David; Jonson, Ida; Dahl, John A; Moen, Marivi Nabong; Nordstrand, Line M; Rognes, Torbjørn; Lee, Jeannie T; Klungland, Arne; Kouzarides, Tony; Larsen, Elisabeth.

Stem Cells ; 30(12): 2672-82, 2012 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-22961808

7.

Unraveling the kinetochore nanostructure in Schizosaccharomyces pombe using multi-color SMLM imaging.

Virant, David; Vojnovic, Ilijana; Winkelmeier, Jannik; Endesfelder, Marc; Turkowyd, Bartosz; Lando, David; Endesfelder, Ulrike.

J Cell Biol ; 222(4)2023 04 03.

Artículo en Inglés | MEDLINE | ID: mdl-36705602

8.

Calculation of 3D genome structures for comparison of chromosome conformation capture experiments with microscopy: An evaluation of single-cell Hi-C protocols.

Lando, David; Stevens, Tim J; Basu, Srinjan; Laue, Ernest D.

Nucleus ; 9(1): 190-201, 2018 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-29431585

9.

Combining fluorescence imaging with Hi-C to study 3D genome architecture of the same single cell.

Lando, David; Basu, Srinjan; Stevens, Tim J; Riddell, Andy; Wohlfahrt, Kai J; Cao, Yang; Boucher, Wayne; Leeb, Martin; Atkinson, Liam P; Lee, Steven F; Hendrich, Brian; Klenerman, Dave; Laue, Ernest D.

Nat Protoc ; 13(5): 1034-1061, 2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29674753

10.

FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells.

Basu, Srinjan; Needham, Lisa-Maria; Lando, David; Taylor, Edward J R; Wohlfahrt, Kai J; Shah, Devina; Boucher, Wayne; Tan, Yi Lei; Bates, Lawrence E; Tkachenko, Olga; Cramard, Julie; Lagerholm, B Christoffer; Eggeling, Christian; Hendrich, Brian; Klenerman, Dave; Lee, Steven F; Laue, Ernest D.

Nat Commun ; 9(1): 2520, 2018 06 28.

Artículo en Inglés | MEDLINE | ID: mdl-29955052

11.

Virtual-'light-sheet' single-molecule localisation microscopy enables quantitative optical sectioning for super-resolution imaging.

Palayret, Matthieu; Armes, Helen; Basu, Srinjan; Watson, Adam T; Herbert, Alex; Lando, David; Etheridge, Thomas J; Endesfelder, Ulrike; Heilemann, Mike; Laue, Ernest; Carr, Antony M; Klenerman, David; Lee, Steven F.

PLoS One ; 10(4): e0125438, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-25884495

12.

The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.

Lando, David; Balmer, Jenny; Laue, Ernest D; Kouzarides, Tony.

PLoS One ; 7(1): e29765, 2012.

Artículo en Inglés | MEDLINE | ID: mdl-22235339

13.

Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast.

Lando, David; Endesfelder, Ulrike; Berger, Harald; Subramanian, Lakxmi; Dunne, Paul D; McColl, James; Klenerman, David; Carr, Antony M; Sauer, Markus; Allshire, Robin C; Heilemann, Mike; Laue, Ernest D.

Open Biol ; 2(7): 120078, 2012 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-22870388

14.

Drug discovery in the HIF pathway: where do we go now?

Lando, David.

Drug Discov Today ; 9(18): 782-3, 2004 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-15364064

15.

Mammalian two-hybrid assay showing redox control of HIF-like factor.

Lando, David; Peet, Daniel J; Pongratz, Ingemar; Whitelaw, Murray L.

Methods Enzymol ; 353: 3-10, 2002.

Artículo en Inglés | MEDLINE | ID: mdl-12078504

16.

Oxygen-dependent asparagine hydroxylation.

Peet, Daniel J; Lando, David; Whelan, Dean A; Whitelaw, Murray L; Gorman, Jeffrey J.

Methods Enzymol ; 381: 467-87, 2004.

Artículo en Inglés | MEDLINE | ID: mdl-15063693

17.

Genome-wide studies of histone demethylation catalysed by the fission yeast homologues of mammalian LSD1.

Opel, Michael; Lando, David; Bonilla, Carolina; Trewick, Sarah C; Boukaba, Abdelhalim; Walfridsson, Julian; Cauwood, James; Werler, Petra J H; Carr, Antony M; Kouzarides, Tony; Murzina, Natalia V; Allshire, Robin C; Ekwall, Karl; Laue, Ernest D.

PLoS One ; 2(4): e386, 2007 Apr 18.

Artículo en Inglés | MEDLINE | ID: mdl-17440621

18.

Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation.

Lando, David; Gorman, Jeffrey J; Whitelaw, Murray L; Peet, Daniel J.

Eur J Biochem ; 270(5): 781-90, 2003 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-12603311

19.

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch.

Lando, David; Peet, Daniel J; Whelan, Dean A; Gorman, Jeffrey J; Whitelaw, Murray L.

Science ; 295(5556): 858-61, 2002 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-11823643

20.

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor.

Lando, David; Peet, Daniel J; Gorman, Jeffrey J; Whelan, Dean A; Whitelaw, Murray L; Bruick, Richard K.

Genes Dev ; 16(12): 1466-71, 2002 Jun 15.

Artículo en Inglés | MEDLINE | ID: mdl-12080085

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