1.
Org Lett
; 26(15): 3097-3102, 2024 Apr 19.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38574397
RESUMEN
This study introduces a novel approach involving XB-mediated cross-coupling of α-trifluoromethylated alkyl bromides with coumarins and quinolinones under visible light irradiation. Both density functional theory (DFT) calculations and experimental studies converge to suggest that the noncovalent interaction between alkyl bromides and DMAP, intensified by the α-trifluoromethyl group, plays a pivotal role in facilitating this chemoselective reaction.