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1.
p53 missense mutant G242A subverts natural killer cells in sheltering mouse breast cancer cells against immune rejection.
Exp Cell Res
; 417(1): 113210, 2022 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35597298
2.
Rubusoside-assisted solubilization of poorly soluble C6-Ceramide for a pilot pharmacokinetic study.
Prostaglandins Other Lipid Mediat
; 146: 106402, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31841664
3.
Gefitinib versus vinorelbine plus cisplatin as adjuvant treatment for stage II-IIIA (N1-N2) EGFR-mutant NSCLC (ADJUVANT/CTONG1104): a randomised, open-label, phase 3 study.
Lancet Oncol
; 19(1): 139-148, 2018 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29174310
4.
Graviola (Annona muricata) Exerts Anti-Proliferative, Anti-Clonogenic and Pro-Apoptotic Effects in Human Non-Melanoma Skin Cancer UW-BCC1 and A431 Cells In Vitro: Involvement of Hedgehog Signaling.
Int J Mol Sci
; 19(6)2018 Jun 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-29914183
5.
Highly and moderately aggressive mouse ovarian cancer cell lines exhibit differential gene expression.
Tumour Biol
; 37(8): 11147-11162, 2016 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26935058
6.
Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells.
Biochim Biophys Acta
; 1841(11): 1571-80, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25195822
7.
Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling.
Org Biomol Chem
; 12(28): 5295-303, 2014 Jul 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-24927150
8.
3-Ketone-4,6-diene ceramide analogs exclusively induce apoptosis in chemo-resistant cancer cells.
Bioorg Med Chem
; 22(4): 1412-20, 2014 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24457089
9.
Ceramide glycosylation by glucosylceramide synthase selectively maintains the properties of breast cancer stem cells.
J Biol Chem
; 287(44): 37195-205, 2012 Oct 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-22936806
10.
Assessment of Antitumor and Antiproliferative Efficacy and Detection of Protein-Protein Interactions in Cancer Cells from 3D Tumor Spheroids.
Curr Protoc
; 2(10): e569, 2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-36286844
11.
Real-World Survival Outcomes Based on EGFR Mutation Status in Chinese Patients With Lung Adenocarcinoma After Complete Resection: Results From the ICAN Study.
JTO Clin Res Rep
; 3(1): 100257, 2022 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-34977823
12.
Efficacy and safety of esophagectomy via left thoracic approach versus via right thoracic approach for middle and lower thoracic esophageal cancer: a multicenter randomized clinical trial (NST1501).
Ann Transl Med
; 10(16): 904, 2022 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-36111056
13.
Mutant p53 exhibits trivial effects on mitochondrial functions which can be reactivated by ellipticine in lymphoma cells.
Apoptosis
; 16(3): 301-10, 2011 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-21107702
14.
Gefitinib Versus Vinorelbine Plus Cisplatin as Adjuvant Treatment for Stage II-IIIA (N1-N2) EGFR-Mutant NSCLC: Final Overall Survival Analysis of CTONG1104 Phase III Trial.
J Clin Oncol
; 39(7): 713-722, 2021 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33332190
15.
Genomic signatures define three subtypes of EGFR-mutant stage II-III non-small-cell lung cancer with distinct adjuvant therapy outcomes.
Nat Commun
; 12(1): 6450, 2021 11 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34750392
16.
Direct quantitative determination of ceramide glycosylation in vivo: a new approach to evaluate cellular enzyme activity of glucosylceramide synthase.
J Lipid Res
; 51(4): 866-74, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19826105
17.
Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and beta-catenin signaling.
Mol Cancer
; 9: 145, 2010 Jun 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-20540746
18.
Gb3-cSrc complex in glycosphingolipid-enriched microdomains contributes to the expression of p53 mutant protein and cancer drug resistance via ß-catenin-activated RNA methylation.
FASEB Bioadv
; 2(11): 653-667, 2020 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-33205006
19.
Ceramide-Rubusoside Nanomicelles, a Potential Therapeutic Approach to Target Cancers Carrying p53 Missense Mutations.
Mol Cancer Ther
; 19(2): 564-574, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31645443
20.
Quality of life with adjuvant gefitinib versus vinorelbine plus cisplatin in patients with completely resected stage II-IIIA (N1-N2) EGFR-mutant non-small-cell lung cancer: Results from the ADJUVANT (CTONG1104) study.
Lung Cancer
; 150: 164-171, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33186858