1.
J Org Chem
; 88(21): 15060-15066, 2023 Nov 03.
Artículo
en Inglés
| MEDLINE
| ID: mdl-37847050
RESUMEN
Manipulating carbon-centered radicals to add to electron-deficient systems is a well-precedented process. By coupling the Fe(II)-mediated Fenton reaction with the Fe(III)-mediated single-electron oxidation of anisolic compounds, we demonstrate how electron-rich carbon-centered radicals can react with electron-rich arenes through a radical-polar cascade pathway. This bioinspired approach produces diarylmethane derivatives from simple unfunctionalized precursors.