Qualitative and quantitative analysis of the CTX in relation to the period of intake of bisphosphonates: A systematic review.

The aim of this systematic review was to determinate the true value of C-terminal crosslinking telopeptide test (CTX) in patient who takes Bisphosphonate. A comprehensive search of studies published up to March 2020 and listed in the PubMed/MEDLINE and Cochrane Library databases, was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta- Analyses (PRISMA) guidelines. The search identified 99 publications; 6 studies were finally deemed eligible for inclusion according to the study criteria. These studies included a total 104 patients and was selected 101. The CTX value in the various study groups is less than 150 pg/ml. There is a difference between the age of the patient and the period of taking the drug. This systematic review indicates that the CTX test has diffent predictive value in determining the risk of osteonecrosis in patients taking bisphosphonate compared to previus standard.

Comparative analysis of the peri-implant tissue response of standard versus short implants in smoker, non-smoker and former smoker patients: a one-year retrospective study.

The aim of this clinical study is to evaluate, through some clinical and radiographic tests, the different biological responses of hard and soft tissues adjacent to the standard or to reduced-length implants in smokers, non-smokers and former smokers. This study was a comparative analysis of three groups of patients. Patients were eligible if they needed an implant in the posterior areas of the maxilla and mandible, both with a sufficient amount of bone, using implants that are standard or with small heights, and using small implants so that they could avoid any regenerative bone therapy aimed at increasing vertical size. The clinical and X-ray assessment was performed after 4/6 months (T1) and after one year (T2). The main results were recordings of clinical aspects such as presence of inflammation, color and gum appearance assessments, and X-ray assessment differentiating maxilla and mandible implants. Averages were conducted to estimate differences between study groups. One-hundred patients were included, with a total of 200 implants: 100 standard sized implants and 100 short implants. In the individual study groups, there is no difference between the types of implants, and we have favorable and unfavorable conditions. The reported data and the analyzed studies are insufficient to define the influence of smoking in the assessment of the long-term predictability of implants.

Association between obesity and periodontal disease in children.

AIM: The objective of this study was to analyse the relationship between obesity and periodontal disease in children. The null hypothesis is that obese and normal weight children show no different degree of periodontal status. MATERIALS AND METHODS: The sample for this case control study consisted of 20 males and 24 females with a mean age of 9.43±2.05 years old and mean body mass index standard deviation score (BMI-SDS) of 2.16±0.37 in the test group, and 33 males and 26 females with a mean age of 9.67±1.46 years old and BMI-SDS of 0.22±1.79 in the control group. The periodontal status was assessed using plaque accumulation, bleeding on probing (BOP) index, probing depth (PD) and clinical attachment level (CAL). RESULTS: The test group showed higher plaque deposits and BOP and the difference between the two groups was statistically significant (p< 0.05). No significant difference between the two groups was found regarding the loss of clinical attachment, though it was worse in obese children. Categorical variables described as frequency and percentage were compared using the Fisher's exact test or test chi square. Continuous variables were analysed using the Mann-Whitney test. CONCLUSION: The study showed an association between obesity and periodontal risk indicators in children that in the long term may lead to oral conditions. The oral health of overweight/obese subjects should be more carefully supervised and checked in order to prevent oral alterations.