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1.
Arq Bras Endocrinol Metabol ; 57(8): 612-6, 2013 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-24343629

RESUMEN

OBJECTIVE: To determine the frequency of colon cancer, primary hyperparathyroidism, thyroid tumor, and skin cancer in all acromegalic patients in follow-up at the Clinics Hospital - Botucatu Medical School, from 2005 to 2011. SUBJECTS AND METHODS: These patients were evaluated retrospectively for colon cancer, primary hyperparathyroidism, dermatological, and thyroid tumors. RESULTS: Of 29 patients included at the beginning of the study, two were excluded. Among 19 patients submitted to colonoscopy, one presented colon adenocarcinoma (5%). Thyroid nodules were present in 63% of patients, and papilliferous carcinoma was confirmed in two patients (7,7%). Four patients were confirmed as having primary hyperparathyroidism (15%). The most common dermatologic lesions were thickened skin (100%), acrochordons (64%), epidermal cysts (50%), and pseudo-acanthosis nigricans (50%). Only one patient presented basal cell carcinoma. CONCLUSION: Although a small number of acromegalic patients was studied, our findings confirm the high frequency of thyroid neoplasias and primary hyperparathyroidism in this group of patients.


Asunto(s)
Acromegalia/complicaciones , Adenocarcinoma/epidemiología , Neoplasias del Colon/epidemiología , Hiperparatiroidismo Primario/epidemiología , Neoplasias Cutáneas/epidemiología , Nódulo Tiroideo/epidemiología , Acantosis Nigricans/diagnóstico , Acromegalia/sangre , Adenocarcinoma/diagnóstico , Adulto , Anciano , Neoplasias del Colon/diagnóstico , Femenino , Humanos , Hiperparatiroidismo Primario/diagnóstico , Factor I del Crecimiento Similar a la Insulina/análisis , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Neoplasias Cutáneas/diagnóstico , Nódulo Tiroideo/diagnóstico
2.
Arq. bras. endocrinol. metab ; Arq. bras. endocrinol. metab;57(8): 612-616, Nov. 2013. tab
Artículo en Inglés | LILACS | ID: lil-696900

RESUMEN

OBJECTIVE: To determine the frequency of colon cancer, primary hyperparathyroidism, thyroid tumor, and skin cancer in all acromegalic patients in follow-up at the Clinics Hospital - Botucatu Medical School, from 2005 to 2011. SUBJECTS AND METHODS: These patients were evaluated retrospectively for colon cancer, primary hyperparathyroidism, dermatological, and thyroid tumors. RESULTS: Of 29 patients included at the beginning of the study, two were excluded. Among 19 patients submitted to colonoscopy, one presented colon adenocarcinoma (5%). Thyroid nodules were present in 63% of patients, and papilliferous carcinoma was confirmed in two patients (7,7%). Four patients were confirmed as having primary hyperparathyroidism (15%). The most common dermatologic lesions were thickened skin (100%), acrochordons (64%), epidermal cysts (50%), and pseudo-acanthosis nigricans (50%). Only one patient presented basal cell carcinoma. CONCLUSION: Although a small number of acromegalic patients was studied, our findings confirm the high frequency of thyroid neoplasias and primary hyperparathyroidism in this group of patients.


OBJETIVO: Determinar a frequência de câncer de cólon, hiperparatireoidismo primário, tumores de tireoide e pele em todos os acromegálicos em seguimento no Hospital de Clínicas da Faculdade de Medicina de Botucatu de 2005 a 2011. SUJEITOS E MÉTODOS: Esses pacientes foram avaliados retrospectivamente quanto a presença de câncer de cólon, hiperparatiroidismo primário, tumores da tiroide e pele. RESULTADOS: Dos 29 pacientes incluídos no início do estudo, dois foram excluídos. Dentre os 19 pacientes submetidos à colonoscopia, um apresentou adenocarcinoma de cólon (5%). Nódulos de tireoide estiveram presentes em 65% dos pacientes e carcinoma papilífero, em dois deles (7,7%). Quatro pacientes apresentaram hiperparatireoidismo primário (15%). A maioria das lesões de pele foram: espessamento (100%), acrochordons (64%), cistos epidérmicos (50%), pseudoacantose nigricans (50%) e apenas um paciente apresentou carcinoma basocelular. CONCLUSÃO: O tamanho da amostra é pequeno, mas nossos achados confirmam a alta frequência da neoplasia da tireoide e hiperparatireroidismo neste grupo de pacientes.


Asunto(s)
Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Acromegalia/complicaciones , Adenocarcinoma/epidemiología , Neoplasias del Colon/epidemiología , Hiperparatiroidismo Primario/epidemiología , Neoplasias Cutáneas/epidemiología , Nódulo Tiroideo/epidemiología , Acantosis Nigricans/diagnóstico , Acromegalia/sangre , Adenocarcinoma/diagnóstico , Neoplasias del Colon/diagnóstico , Hiperparatiroidismo Primario/diagnóstico , Factor I del Crecimiento Similar a la Insulina/análisis , Estudios Retrospectivos , Neoplasias Cutáneas/diagnóstico , Nódulo Tiroideo/diagnóstico
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