An uncommon cause of retropharyngeal abscess in adults: Cervical pyogenic spondylodiscitis.

INTRODUCTION AND IMPORTANCE: Retropharyngeal abscess (RPA) represents a rare and life-threatening condition, particularly uncommon in the adult population. The simultaneous occurrence of RPA, and cervical spondylodiscitis is an exceedingly infrequent situation. CASE PRESENTATION: we reported the case of a 67-year-old male who presented to our department with complaints of sore throat, restricted neck range of motion, as well as numbness and weakness in the right arm persisting for two weeks. Cervical computed tomography identified a retropharyngeal abscess measuring 15 cm in height around C3 to D3. Subsequent cervical magnetic resonance imaging disclosed revealed infectious spondylodiscitis at C5-C6-C7 and partially collected epiduritis from C5 to C7. The abscess was promptly drained by the transoral way. Following the procedures, the patient was discharged with a cervical collar and a prescribed course of antibiotics. CLINICAL DISCUSSION: Cervical retropharyngeal abscesses complicating spondylodiscitis is very rare. The clinical symptoms are variable and nonspecific. Given the potentially life-threatening nature of this condition, its management represents a real challenge. CONCLUSION: The management of such complex cases necessitates a multidisciplinary approach involving otolaryngologists, neurosurgeons, and infectious disease specialists to mitigate the risk of complications and prevent any potential delays in treatment.

[Role of ALAT level in preventing post-transfusional hepatitis. Prospective study of 1,180 blood donors in Tunisia]. / Intérêt du dosage de l'ALAT dans la prévention des hépatites post transfusionnelles. Etude prospective à propos de 1180 donneurs de sang du sahel tunisien.

In Tunisia, regular serological tests for prevention of blood transmitted hepatitis consist in the research of HBS antigen and HCV antibodies. Our purpose in this study is to estimate the prevalence of hypertransaminasemia in blood-donors and to determinate to what extent it could prevent blood-transmitted hepatitis. Therefore we have assessed ALAT sera level in 1180 blood-donors. It rate is considered elevated if higher than twofold the normal rate (> N = 40 Ul/l). Donors with high ALAT level were summoned three months later after their blood gift to undergo clinical examination and a new serological test, researching seroconversion of HBS Ag and HCV antibodies. With regarding to estimation of residuel HCV infection risk, we were based on M.P Busch's data. Hpertransaminasemia was modified in 134 individuals (11.5%). Only 67 had replied to our summons. Alcoholism was involved in one case. Smoking was found in most of male donors. We had discovered neither weight excess nor drug or medicines consumption which could explain increasing ALAT. New serological list had revealed seroconversion for HCV antibodies in ELISA but with undeterminated profile in Immunoblot (anti NS5 solely). PCR was not carried out. Residual infection risk being considered, use of hypertransaminasemia detection in blood donors should prevent nearly 1.67 blood transmitted hepatitis per million transfusions units. However if we consider shortage in blood derivates in Tunisia, such a decision should be comprehensively weighted numerous blood donors will be moved aside.