Enlightenment of re-entry airflow: The path of the airflow and the airborne pollutants transmission in buildings.

Viable aerosols in the airflow may increase the risk of occupants contracting diseases. Natural ventilation is common in buildings and is accompanied by re-entry airflow during the ventilation process. If the re-entry airflow contains toxic or infectious species, it may cause potential harm to residents. One of the Covid-19 outbreaks occurred in a public residential building at Luk Chuen House (LC-House) in Hong Kong. It is highly suspected that the outbreak of the disease is related to the re-entry airflow. The study attempts to explain and discuss possible causes of the outbreak. In order to understand the impact of airflow on the outbreak, a public residential building similar to LC-House was used in the study. Two measurements M - I and M - II with the same settings were conducted for a sampling unit in the corridor under low and strong wind conditions respectively. The sampling unit and the tracer gas carbon dioxide (CO2) were used to simulate the index unit and infectious contaminated airflow respectively. The CO2 concentrations of the unit and corridor were measured simultaneously. Two models of Traditional Single-zone model (TSZ-model) and New Dual-zone model (NDZ-model) were used in the analysis. By comparing the ACH values obtained from the two models, it is indicated that the re-entry airflow of the unit is related to the corridor wind speeds and this provides a reasonable explanation for the outbreak in LC-House, and believes that the results can help understand the recent frequent cluster outbreaks in other residential buildings.

[MRI findings and pathological features of occult breast cancer].

Objective: To investigate the magnetic resonance imaging (MRI) findings and clinicopathological features of primary lesions in patients with occult breast cancer (OBC). Methods: The imaging reports from the Breast Imaging Reporting and Data System in 2013 were retrospectively analyzed to investigate the morphology and the time signal intensity curve (TIC) of breast lesions in patients with OBC. The clinical and pathological characteristics of these patients were also included. Results: A total of 34 patients were enrolled. Among these patients, 24 patients underwent modified radical mastectomy and 18 of them had primary breast carcinoma in pathological sections. MRI detected 17 cases of primary lesions, including six masse lesions with a diameter of 0.6-1.2 cm (average 0.9 cm), and 11 non-mass lesions with four linear distributions, three segmental distributions, three focal distributions, and one regions distribution. Five patients had TIC typeⅠprimary lesions, ten had TIC type Ⅱ primary lesions, and two had TIC type Ⅲ primary lesions. Among all 34 cases, 23 of them had complete results of immunohistochemistry: 11 estrogen receptor (ER) positive lesions (47.8%), tenprogesterone receptor (PR) positive lesions (43.5%), seven human epidermal growth factor receptor 2 (HER-2) positive lesions (30.4%), and 20high expression(>14%) of Ki-67 (87.0%). The proportion of type luminal A was 4.3%, type luminal B was 43.5%, triple negative breast cancer (TNBC) was 30.4%, and HER-2 over expression accounted for 21.7%. Conclusions: The primary lesions of OBC usually manifested as small mass lesions, or focal, linear or segmental distribution of non-mass lesions. The positive rate of ER and PR was low, but the positive rate of HER-2 and the proliferation index of Ki-67 was high. Type luminal B is the most common molecular subtype.

Numerical investigation of wind-induced airflow and interunit dispersion characteristics in multistory residential buildings.

Compared with the buoyancy-dominated upward spread, the interunit dispersion of pollutants in wind-dominated conditions is expected to be more complex and multiple. The aim of this study is to investigate the wind-induced airflow and interunit pollutant dispersion in typical multistory residential buildings using computational fluid dynamics. The mathematical model used is the nonstandard k-ε model incorporated with a two-layer near-wall modification, which is validated against experiments of previous investigators. Using tracer gas technique, the reentry of exhaust air from each distinct unit to other units on the same building, under different practical conditions, is quantified, and then, the possible dispersion routes are revealed. The units on the floor immediately below the source on the windward side, and vertically above it on the leeward side, where the reentry ratios are up to 4.8% and 14.9%, respectively, should be included on the high-infection list. It is also found that the presence of balconies results in a more turbulent near-wall flow field, which in turn significantly changes the reentry characteristics. Comparison of the dispersion characteristics of the slab-like building and the more complicated building in cross (#) floorplan concludes that distinctive infectious control measures should be implemented in these two types of buildings.

Measures to prevent goggles from fogging during the treatment of Coronavirus Disease 2019.

During these challenging and unprecedented times for the global communities as they battle the COVID-19 pandemic, we found a simple and effective way to prevent the goggles fogging. We hope that it will help the healthcare professionals who are still troubled by the problem of fogging goggles.

The airborne transmission of infection between flats in high-rise residential buildings: Particle simulation.

Several case clusters occurred in high-rise residential buildings in Hong Kong in the 2003 SARS (the severe acute respiratory syndrome) epidemic, which motivated a series of engineering investigations into the possible airborne transport routes. It is suspected that, driven by buoyancy force, the polluted air that exits the window of the lower floor may re-enter the immediate upper floor through the window on the same side. This cascade effect has been quantified and reported in a previous paper, and it is found that, by tracer gas concentration analysis, the room in the adjacent upstairs may contain up to 7% of the air directly from the downstairs room. In this study, after validation against the experimental data from literatures, Eulerian and Lagrangian approaches are both adopted to numerically investigate the dispersion of expiratory aerosols between two vertically adjacent flats. It is found that the particle concentration in the upper floor is two to three orders of magnitude lower than in the source floor. 1.0 µm particles disperse like gaseous pollutants. For coarse particles larger than 20.0 µm, strong deposition on solid surfaces and gravitational settling effect greatly limit their upward transport.

The airborne transmission of infection between flats in high-rise residential buildings: Tracer gas simulation.

Airborne transmission of infectious respiratory diseases in indoor environments has drawn our attention for decades, and this issue is revitalized with the outbreak of severe acute respiratory syndrome (SARS). One of the concerns is that there may be multiple transmission routes across households in high-rise residential buildings, one of which is the natural ventilative airflow through open windows between flats, caused by buoyancy effects. Our early on-site measurement using tracer gases confirmed qualitatively and quantitatively that the re-entry of the exhaust-polluted air from the window of the lower floor into the adjacent upper floor is a fact. This study presents the modeling of this cascade effect using computational fluid dynamics (CFD) technique. It is found that the presence of the pollutants generated in the lower floor is generally lower in the immediate upper floor by two orders of magnitude, but the risk of infection calculated by the Wells-Riley equation is only around one order of magnitude lower. It is found that, with single-side open-window conditions, wind blowing perpendicularly to the building may either reinforce or suppress the upward transport, depending on the wind speed. High-speed winds can restrain the convective transfer of heat and mass between flats, functioning like an air curtain. Despite the complexities of the air flow involved, it is clear that this transmission route should be taken into account in infection control.

Modeling particle dispersion and deposition in indoor environments.

Particle dispersion and deposition in man-made enclosed environments are closely related to the well-being of occupants. The present study developed a three-dimensional drift-flux model for particle movements in turbulent indoor airflows, and combined it into Eulerian approaches. To account for the process of particle deposition at solid boundaries, a semi-empirical deposition model was adopted in which the size-dependent deposition characteristics were well resolved. After validation against the experimental data in a scaled isothermal chamber and in a full-scale non-isothermal environmental chamber, the drift-flux model was used to investigate the deposition rates and human exposures to particles from two different sources with three typical ventilation systems: mixing ventilation (MV), displacement ventilation (DV), and under-floor air distribution (UFAD). For particles originating from the supply air, a V-shaped curve of the deposition velocity variation as a function of particle size was observed. The minimum deposition appeared at 0.1- 0.5 µ m . For supermicron particles, the ventilation type and air exchange rate had an ignorable effect on the deposition rate. The movements of submicron particles were like tracer gases while the gravitational settling effect should be taken into account for particles larger than 2.5 µ m . The temporal increment of human exposure to a step-up particle release in the supply air was determined, among many factors, by the distance between the occupant and air outlet. The larger the particle size, the lower the human exposure. For particles released from an internal heat source, the concentration stratification of small particles (diameter < 10 µ m ) in the vertical direction appeared with DV and UFAD, and it was found the advantageous principle for gaseous pollutants that a relatively less-polluted occupied zone existed in DV and UFAD was also applicable to small particles.

[Effect of expanded lateral thoracic abdominal flap transferred with pedicle on repairing large area of hypertrophic scar after burn of the upper extremity].

Objective: To observe the effect of expanded lateral thoracic abdominal flap transferred with pedicle on repairing large area of hypertrophic scar after burn of the upper extremity. Methods: Twelve patients with large area of secondary hypertrophic scar 8 month to 3 years after healing of burn wound on the upper extremity were hospitalized in Zhengzhou First People's Hospital from October 2008 to October 2015, with scar area ranging from 11 cm×7 cm to 20 cm×10 cm. Five patients were with limited straightening and bending of elbow. The scars were reconstructed with ipsilateral expanded lateral thoracic abdominal flap or that combined with expanded upper extremity flap according to the area of scar. Lateral thoracic abdominal incision was located near the anterior axillary line, and upper extremity incision was located near scar edge. A capsule cavity was formed by blunt dissection in the superficial fascia layer. Expander with suitable capacity was implanted with the injection pot being built-in. Volume of water reaching 1 time to 3 times of the capacity of expander was injected for excessive expanding. The expanded lateral thoracic abdominal flap supplied by lateral thoracic cutaneous artery and expanded upper extremity flap were dissected after the completion of expanding. The expanded upper extremity flap was advanced locally to cover the surrounding secondary wound after resection of hypertrophic scar. The expanded lateral thoracic abdominal flap was transferred with pedicle to reconstruct scar, with pedicle being sutured in skin tube-like shape, and the flap donor site was sutured directly. Flap pedicle separation was carried out 3 weeks after surgery. Anti-scar treatment was carried out after healing of sutured area. Results: Totally 18 expanders were implanted, without complications such as infection, exposure of expander, and so on. The areas of expanded lateral thoracic abdominal flaps were from 11 cm×7 cm to 16 cm×11 cm. The combined application of expanded upper extremity flaps with area ranging from 8 cm×4 cm to 9 cm×6 cm was used in 6 patients. All the flaps survived with incision healed. The color, texture, and thickness of skin area repaired by flap were close to those of the normal skin of upper extremity after 6 months to 2 years' follow-up afer discharge. The limited straightening and bending of elbow in 5 patients were rectified. Obvious linear scar was observed in the sutured area of surgery in 3 patients, while light linear scar was observed in the sutured area of surgery in 9 patients. Conclusions: Expanded lateral thoracic abdominal flap has constant blood vessel and is easy to be dissected. It can achieve well reconstruction of appearance and function in repairing large area of hypertrophic scar after burn of the upper extremity.

Characteristics of air pollutant dispersion around a high-rise building.

A numerical wind tunnel model was proposed. The computed results of the pollutant diffusion around a typical Hong Kong high-rise building model (at a linear scale of 1:30), were found to show a similar trend to the outcomes of self-conducted experimental measurements that the pathways of pollutant migration for windward and leeward pollutant emission are different. For the case with windward pollutant emission at the 3rd floor within a re-entry, the pollutant migrated downwards due to the downwash created by the wind. In contrast, for the case with leeward pollution emission, dispersion is dominated by intense turbulent mixing in the near wake and characterized by the upward migration of the pollutant in the leeward re-entry. The simulated results of haze-fog (HF) studies confirm that the pathway of pollutant migration is dominated by wind-structure interaction and buoyancy effect only plays a minor role in the dispersion process.

Setting up the criteria and credit-awarding scheme for building interior material selection to achieve better indoor air quality.

Methods, standards, and regulations that are aimed to reduce indoor air pollution from building materials are critically reviewed. These are classified as content control and emission control. Methods and standards can be found in both of these two classes. In the regulation domain, only content control is enforced in some countries and some regions, and asbestos is the only building material that is banned for building use. The controlled pollutants include heavy metals, radon, formaldehyde, and volatile organic compounds (VOCs). Emission rate control based upon environment chamber testing is very much in the nature of voluntary product labeling and ranking, and this mainly targets formaldehyde and VOC emissions. It is suggested that radon emission from building materials should be subject to similar emission rate control. A comprehensive set criteria and credit-awarding scheme that encourages the use of low-emission building material is synthesized, and how this scheme can be practiced in building design is proposed and discussed.

Analysis of concentration fluctuations in gas dispersion around high-rise building for different incident wind directions.

This article presents experimental results that illustrate the unsteady characteristics of gas dispersion around a complex-shaped high-rise building for different incident wind directions. A series of wind tunnel experiments were conducted using a 1:30 scale model that represented the real structures under study. The objective of this paper is to study the behaviour of concentration fluctuations through transient analysis. Tracer gas was continuously released from a point source located at different positions, and a time series of fluctuating concentrations were recorded at a large number of points using fast flame ionization detectors. The experimental data were analysed to provide a comprehensive data set including variances and associated statistical quantities. Both the unsteady characteristics of the system and their potential practical impact are presented and discussed. Under crowd living conditions, the air pollutant exhausted from one household could probably re-enter into the neighbouring households, traveling with ambient airflow. Such pollutant dispersion process is defined as air cross-contamination in this study. The results indicate that the wind-induced cross-contamination around the studied type of high-rise building should not be overlooked, and the fluctuating concentrations should be paid attention to particularly during the evaluation of a potential contamination risk. This study can help deepen our understanding of the mechanisms of air cross-contamination, and will be useful for implementing optimization strategies to improve the built environments in metropolitan cities such as Hong Kong.

Local characteristics of cross-unit contamination around high-rise building due to wind effect: mean concentration and infection risk assessment.

In this present work, the characteristics of hazardous gas dispersion and possible cross-unit contamination around a complex-shaped high-rise residential building due to wind effect are thoroughly studied using physical modeling method. Experiments were performed in a boundary layer wind tunnel for a 1:30 scale model that represented a 10-story residential building in prototype. Tracer gas, simulating exhausted room air, was continuously released from different floor levels, and its concentrations on the adjacent envelope surfaces were measured using fast flame ionization detectors. The mean concentration fields were reported and analyzed under different configurations during the experiment to consider the effects on pollutant dispersion behavior due to changes in source position and approaching wind condition, with the main emphasis on the differences between open-window and closed-window conditions. In particular, the measured concentration fields were further examined from a practical point of view, with respect to hazard assessment. Understanding these hazardous plume dispersion features is useful for employing effective intervention strategies in modern residential building environment in case of hazardous substance release. The study on this physical process is not only helpful to reduce the hazardous effect of routine release of harmful pollutant near the building, but also useful for the purpose of prevention and control of accidental infectious diseases outbreak.

CFD Simulation of Spread Risks of Infectious Disease due to Interactive Wind and Ventilation Airflows via Window Openings in High-Rise Buildings.

One of the concerns is that there may exist multiple infectious disease transmission routes across households in high-rise residential buildings, one of which is the natural ventilative airflow through open windows between flats, caused by buoyancy effects. This study presents the modeling of this cascade effect using computational fluid dynamics (CFD) technique. It is found that the presence of the pollutants generated in the lower floor is generally lower in the immediate upper floor by two orders of magnitude, but the risk of infection calculated by the Wells-Riley equation is only around one order of magnitude lower. It is found that, with single-side open-window conditions, wind blowing perpendicularly to the building may either reinforce or suppress the upward transport, depending on the wind speed. High-speed winds can restrain the convective transfer of heat and mass between flats, functioning like an air curtain. Despite the complexities of the air flow involved, it is clear that this transmission route should be taken into account in infection control.

Effects of turbulent air on human thermal sensations in a warm isothermal environment.

Air movement can provide desirable cooling in "warm" conditions, but it can also cause discomfort. This study focuses on the effects of turbulent air movements on human thermal sensations through investigating the preferred air velocity within the temperature range of 26 degrees C and 30.5 degrees C at two relative humidity levels of 35% and 65%. Subjects in an environmental chamber were allowed to adjust air movement as they liked while answering a series of questions about their thermal comfort and draft sensation. The results show that operative temperature, turbulent intensity and relative humidity have significant effects on preferred velocities, and that there is a wide variation among subjects in their thermal comfort votes. Most subjects can achieve thermal comfort under the experimental conditions after adjusting the air velocity as they like, except at the relative high temperature of 30.5 degrees C. The results also indicate that turbulence may reduce draft risk in neutral-to-warm conditions. The annoying effect caused by the air pressure and its drying effect at higher velocities should not be ignored. A new model of Percentage Dissatisfied at Preferred Velocities (PDV) is presented to predict the percentage of feeling draft in warm isothermal conditions.