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Otol Neurotol ; 32(6): 1025-30, 2011 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-21725270

RESUMEN

OBJECTIVES: To determine if an accurate prognosis can be made in patients with Herpes zoster oticus (HZO), facial nerve outcomes were assessed at 1-year after onset and compared with symptoms and signs at presentation. STUDY DESIGN: Individual retrospective cohort study of 101 records in a case series (level of evidence: Level 2b). METHODS: Symptoms, signs, audiology, and treatment records were analyzed to determine their association with facial nerve outcome at 1 year. RESULTS: Mean improvement at 1 year for the 101 patients was 3 House-Brackmann (HB) grade units. Initially, severity ranged from HB III to HB VI. Mean recovery was significantly greater for those patients who were initially more affected, although at 1 year, they had still not recovered to the same grade as those initially less affected. Having both incomplete eye closure and a dry eye was associated with less recovery at 1 year. The use of prednisone combined with an antiviral agent, and begun at or after Day 5 of the illness, was related to a better facial nerve outcome. No other symptom, sign, or audiologic feature was of prognostic value. CONCLUSION: All patients with HZO improved facial function to some degree, with the mean gain at 1 year after onset being 3 HB grade units. Improvement was less for patients who initially had both incomplete eye closure and dry eye. The group who received a combination of an antiviral medication with steroids given after 5 days had the best facial nerve outcome.


Asunto(s)
Nervio Facial/fisiopatología , Parálisis Facial/fisiopatología , Herpes Zóster Ótico/diagnóstico , Aciclovir/uso terapéutico , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Antivirales/uso terapéutico , Audiometría de Tonos Puros , Niño , Quimioterapia Combinada , Parálisis Facial/tratamiento farmacológico , Femenino , Glucocorticoides/uso terapéutico , Herpes Zóster Ótico/tratamiento farmacológico , Herpes Zóster Ótico/fisiopatología , Humanos , Masculino , Persona de Mediana Edad , Prednisona/uso terapéutico , Pronóstico , Recuperación de la Función/fisiología , Estudios Retrospectivos , Resultado del Tratamiento
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