RESUMEN
We present the case of a pregnant woman with arthritis in treatment with etanercept. After becoming pregnant she continued treatment with standard doses of this drug, 25 mg twice a week, without complications.
Asunto(s)
Artritis Juvenil/tratamiento farmacológico , Inmunoglobulina G/uso terapéutico , Complicaciones del Embarazo/tratamiento farmacológico , Receptores del Factor de Necrosis Tumoral/uso terapéutico , Etanercept , Femenino , Humanos , Inmunoglobulina G/administración & dosificación , Recién Nacido , Embarazo , Resultado del Embarazo , Receptores del Factor de Necrosis Tumoral/administración & dosificación , Factores de Tiempo , Resultado del TratamientoRESUMEN
Nosocomial infection is a serious problem of morbidity and mortality that, according to the 2003 national prevalence data affected 6,5-7% of all the patients admitted in Spanish hospitals. Our aim is to assess the prevalence of nosocomial infection in Navarre, from the aggregated data of each participant in the EPINE (Study of Prevalence of Nosocomial Infection in Spain) in 2005, and to analyse different features of the nosocomial infections to compare them with the global data for Spain. The prevalence of patients with nosocomial infection was 5,6% and the prevalence of patients with community infection was 13,2%. The prevalence of nosocomial infection, excluding those that acquired the nosocomial infection in a previous admission to the hospital, was 6,2%. The prevalence of community infection was 14,2%.
Asunto(s)
Infección Hospitalaria/epidemiología , Áreas de Influencia de Salud , Infección Hospitalaria/microbiología , Humanos , Incidencia , Persona de Mediana Edad , Prevalencia , España/epidemiologíaAsunto(s)
Antibacterianos/efectos adversos , Artralgia/inducido químicamente , Artritis/inducido químicamente , Levofloxacino , Ofloxacino/efectos adversos , Antibacterianos/uso terapéutico , Artritis Infecciosa/tratamiento farmacológico , Artritis Infecciosa/cirugía , Artroplastia de Reemplazo de Rodilla , Atorvastatina , Terapia Combinada , Desbridamiento , Diagnóstico Diferencial , Doxiciclina/uso terapéutico , Interacciones Farmacológicas , Femenino , Ácidos Heptanoicos/efectos adversos , Ácidos Heptanoicos/uso terapéutico , Humanos , Inhibidores de Hidroximetilglutaril-CoA Reductasas/efectos adversos , Inhibidores de Hidroximetilglutaril-CoA Reductasas/uso terapéutico , Hiperlipoproteinemia Tipo II/complicaciones , Hiperlipoproteinemia Tipo II/tratamiento farmacológico , Persona de Mediana Edad , Ofloxacino/uso terapéutico , Complicaciones Posoperatorias/inducido químicamente , Infecciones Relacionadas con Prótesis/tratamiento farmacológico , Infecciones Relacionadas con Prótesis/cirugía , Pirroles/efectos adversos , Pirroles/uso terapéutico , Recurrencia , Reoperación , Rifampin/efectos adversos , Rifampin/uso terapéutico , Tiroiditis Autoinmune/complicaciones , Tiroiditis Autoinmune/tratamiento farmacológico , Tiroxina/uso terapéutico , Combinación Trimetoprim y Sulfametoxazol/uso terapéuticoRESUMEN
OBJECTIVE: To assess the prevalence of carpal tunnel syndrome (CTS) in patients with fibromyalgia syndrome (FM). METHODS: A series of 206 consecutive patients with FM was evaluated for CTS in an unblinded, uncontrolled study. Sixty patients with dermatomal paresthesia in the fingers enervated by the median nerve were evaluated with electromyogram and nerve conduction velocity studies (EMG/NCV). RESULTS: Thirty-three patients showed EMG/NCV findings diagnostic for CTS (16% of the 206 cases, 55% of the 60 EMG studies). Only 2 of the 33 patients with CTS had been diagnosed before rheumatologic evaluation. We compared our results with those reported for women in the general population. The overall prevalence of CTS in women was higher (16 vs 10.2%), but not statistically different. However, in our series, there was a clear difference in the higher rate of undetected CTS in women with FM compared to that of the general population (14.1 vs 6.7%) (p < 0.01). CONCLUSION: (1) CTS is at least as common in patients with FM as in the general population, contrary to that reported in retrospective studies; (2) the rate of underdiagnosed CTS in women with FM is much higher than the rate reported in the general population; (3) NCV studies may be necessary to evaluate underdiagnosed CTS in patients with FM and dermatomal paresthesia in their hands.
Asunto(s)
Síndrome del Túnel Carpiano/complicaciones , Síndrome del Túnel Carpiano/epidemiología , Fibromialgia/complicaciones , Adolescente , Adulto , Anciano , Síndrome del Túnel Carpiano/diagnóstico , Electromiografía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Conducción Nerviosa , PrevalenciaRESUMEN
AIM: Cytomegalovirus colitis occurs in at least 5-10% of patients with AIDS. The most usual form of clinical presentation is that of a chronic picture of diarrhea, fever and abdominal pain in a patient with AIDS with a CD4 lymphocyte count lower than 100/mm3, although it can be the diagnostic index for AIDS up to in 25% of the cases. METHODS: Cytomegalovirus colitis in a patient with AIDS was diagnosed by endoscopy and colonic biopsy. The clinical was diagnosed by endoscopy and colonic biopsy. The clinical picture consisted of abdominal pain, without the findings of fever and diarrhea described in almost 80% and 100% respectively of the cases published in the literature. The barium enema carried out showed a stenotic appearance, like serviette ring, in the ascending colon, which suggested neoplasia of the colon. RESULTS: Induction therapy with ganciclovir was effective. However, the patient was readmitted one year later for chorioretinitis due to cytomegalovirus, without any evidence of gastro-intestinal involvement. CONCLUSIONS: Although unusual, cytomegalovirus colitis can be present with an abdominal clinical picture without diarrhea. Radiological and/or endoscopic pseudotumoral forms which this entity can adopt are often described. Endoscopy with digestive biopsy in essential for diagnosis. Therapy with ganciclovir can be effective although the reappearance of findings from cytomegalovirus can occur at another area, or as a gastrointestinal recurrence.