RESUMEN
Following a seventeen weeks study including 110 patients with open-angle glaucoma, 81,8% of the patients treated by timolol, administered twice a day, had a satisfactory control of their intraocular pressure, against only 41,8% of those patients treated by pilocarpine, administered four times a day. The side effects liable to timolol are clinically reduced, in a osit with pilocarpine which is followed by a series of well-known subjective and objective signs often causing discomfort to the patients.
Asunto(s)
Glaucoma/tratamiento farmacológico , Pilocarpina/uso terapéutico , Propanolaminas/uso terapéutico , Timolol/uso terapéutico , Anciano , Enfermedad Crónica , Ensayos Clínicos como Asunto , Humanos , Persona de Mediana EdadRESUMEN
A randomized double-blind trial was conducted in 143 out-patients with allergic conjunctivitis (281 eyes). Active sodium cromoglycate collyre was compared with placebo in parallel groups over a four-week period. Highly significant advantage for active drug was demonstrated for subjective and objective symptoms as well as for overall assessment by patients and physicians. Results were compared with international data concerning this well-known anti-allergic compound.