Estimation of Levels of Salivary Pyridinoline Cross-Linked Carboxyterminal Telopeptide of Type I Collagen (ICTP) in Periodontally Healthy and Diseased Patients at Various Time Intervals Before and After Periodontal Therapy.

INTRODUCTION: The bacterial plaque in the tooth-supporting tissues is the main cause of inflammatory conditions called periodontal diseases. Thus, the aim of this study is to determine the levels of intercellular matrix protein (ICTP) in patients with gingivitis and periodontitis and those who are periodontally healthy, both before and after treatment at different times. MATERIALS AND METHODS: Thirty clinical parameters (bleeding on probing, probing pocket depth, and clinical attachment loss) were measured at baseline, one month, three months, and six months after the patients were divided into three groups of 60. RESULTS: There was a significant difference between the two groups at all time intervals; the difference at one month was 34.77 (p=0.000). At three months, the difference became 31.25 (p=0.000) which increased to 36.62 (p=0.000) at six months. CONCLUSION: When periodontal deterioration occurs, ICTP levels are higher, and when they are reduced, periodontal health is demonstrated.