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1.

Excess of circulating apo-transferrin enhances dietary iron absorption.

Tsyplenkova, Sofiya; Charlebois, Edouard; Fillebeen, Carine; Pantopoulos, Kostas.

Blood ; 2024 Mar 25.

Artículo en Inglés | MEDLINE | ID: mdl-38527216

2.

Liver sinusoidal endothelial cells induce BMP6 expression in response to non-transferrin-bound iron.

Charlebois, Edouard; Fillebeen, Carine; Presley, John; Cagnone, Gael; Lisi, Véronique; Lavallée, Vincent-Philippe; Joyal, Jean-Sébastien; Pantopoulos, Kostas.

Blood ; 141(3): 271-284, 2023 01 19.

Artículo en Inglés | MEDLINE | ID: mdl-36351237

3.

The amino acid sensor GCN2 controls red blood cell clearance and iron metabolism through regulation of liver macrophages.

Toboz, Phoenix; Amiri, Mehdi; Tabatabaei, Negar; Dufour, Catherine R; Kim, Seung Hyeon; Fillebeen, Carine; Ayemoba, Charles E; Khoutorsky, Arkady; Nairz, Manfred; Shao, Lijian; Pajcini, Kostandin V; Kim, Ki-Wook; Giguère, Vincent; Oliveira, Regiana L; Constante, Marco; Santos, Manuela M; Morales, Carlos R; Pantopoulos, Kostas; Sonenberg, Nahum; Pinho, Sandra; Tahmasebi, Soroush.

Proc Natl Acad Sci U S A ; 119(35): e2121251119, 2022 08 30.

Artículo en Inglés | MEDLINE | ID: mdl-35994670

4.

Oral iron supplementation: new formulations, old questions.

Pantopoulos, Kostas.

Haematologica ; 2024 Apr 11.

Artículo en Inglés | MEDLINE | ID: mdl-38618666

5.

The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization.

Sun, Juan; Li, Jie; Pantopoulos, Kostas; Liu, Yuqin; He, Yixuan; Kang, Weiming; Ye, Xin.

Cancer Cell Int ; 24(1): 77, 2024 Feb 18.

Artículo en Inglés | MEDLINE | ID: mdl-38369484

6.

Perturbations in lipid metabolism and gut microbiota composition precede cardiac dysfunction in a mouse model of thalassemia.

Liu, Ying; Fillebeen, Carine; Forest, Anik; Botta, Amy; Varin, Thibault V; Marette, André; Burelle, Yan; Des Rosiers, Christine; Pantopoulos, Kostas; Sweeney, Gary.

FASEB J ; 37(12): e23257, 2023 12.

Artículo en Inglés | MEDLINE | ID: mdl-37902616

7.

Iron Deficiency in Anemic Children Surviving Critical Illness: Post Hoc Analysis of a Single-Center Prospective Cohort in Canada, 2019-2022.

Du Pont-Thibodeau, Geneviève; Li, Shu Yin Han; Ducharme-Crevier, Laurence; Jutras, Camille; Pantopoulos, Kostas; Farrell, Catherine; Roumeliotis, Nadia; Harrington, Karen; Thibault, Céline; Roy, Noémi; Shah, Akshay; Lacroix, Jacques; Stanworth, Simon J.

Pediatr Crit Care Med ; 25(4): 344-353, 2024 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-38358779

8.

A Water-Soluble Chitosan Derivative for the Release of Bioactive Deferoxamine.

Michailidou, Georgia; Li, Yupeng; Zamboulis, Alexandra; Karlioti, Georgia; Meimaroglou, Despoina; Pantopoulos, Kostas; Bikiaris, Dimitrios N.

Int J Mol Sci ; 25(2)2024 Jan 11.

Artículo en Inglés | MEDLINE | ID: mdl-38255991

9.

Phosphorus Overload Promotes Hepatic Lipolysis by Suppressing GSK3ß-Dependent Phosphorylation of PPARα at Ser84 and Thr265 in a Freshwater Teleost.

Xu, Yi-Chuang; Pantopoulos, Kostas; Zheng, Hua; Zito, Ester; Zhao, Tao; Tan, Xiao-Ying; Wei, Xiao-Lei; Song, Yu-Feng; Luo, Zhi.

Environ Sci Technol ; 57(6): 2351-2361, 2023 02 14.

Artículo en Inglés | MEDLINE | ID: mdl-36728683

10.

Iron increases lipid deposition via oxidative stress-mediated mitochondrial dysfunction and the HIF1α-PPARÎ³ pathway.

Song, Chang-Chun; Pantopoulos, Kostas; Chen, Guang-Hui; Zhong, Chong-Chao; Zhao, Tao; Zhang, Dian-Guang; Luo, Zhi.

Cell Mol Life Sci ; 79(7): 394, 2022 Jul 04.

Artículo en Inglés | MEDLINE | ID: mdl-35786773

11.

Genetic Iron Overload Hampers Development of Cutaneous Leishmaniasis in Mice.

Charlebois, Edouard; Li, Yupeng; Wagner, Victoria; Pantopoulos, Kostas; Olivier, Martin.

Int J Mol Sci ; 24(2)2023 Jan 14.

Artículo en Inglés | MEDLINE | ID: mdl-36675185

12.

Cardiac Hamp mRNA Is Predominantly Expressed in the Right Atrium and Does Not Respond to Iron.

Bigorra Mir, Maria; Charlebois, Edouard; Tsyplenkova, Sofiya; Fillebeen, Carine; Pantopoulos, Kostas.

Int J Mol Sci ; 24(6)2023 Mar 08.

Artículo en Inglés | MEDLINE | ID: mdl-36982241

13.

Discovery-Based Proteomics Identify Skeletal Muscle Mitochondrial Alterations as an Early Metabolic Defect in a Mouse Model of ß-Thalassemia.

Reboucas, Patricia; Fillebeen, Carine; Botta, Amy; Cleverdon, Riley; Steele, Alexandra P; Richard, Vincent; Zahedi, René P; Borchers, Christoph H; Burelle, Yan; Hawke, Thomas J; Pantopoulos, Kostas; Sweeney, Gary.

Int J Mol Sci ; 24(5)2023 Feb 23.

Artículo en Inglés | MEDLINE | ID: mdl-36901833

14.

Human IRP1 Translocates to the Nucleus in a Cell-Specific and Iron-Dependent Manner.

Gu, Wen; Fillebeen, Carine; Pantopoulos, Kostas.

Int J Mol Sci ; 23(18)2022 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-36142654

15.

Transferrin receptor 1 controls systemic iron homeostasis by fine-tuning hepcidin expression to hepatocellular iron load.

Fillebeen, Carine; Charlebois, Edouard; Wagner, John; Katsarou, Angeliki; Mui, Jeannie; Vali, Hojatollah; Garcia-Santos, Daniel; Ponka, Prem; Presley, John; Pantopoulos, Kostas.

Blood ; 133(4): 344-355, 2019 01 24.

Artículo en Inglés | MEDLINE | ID: mdl-30538134

16.

Macrophage checkpoint for iron absorption.

Pantopoulos, Kostas.

Blood ; 141(23): 2791-2793, 2023 06 08.

Artículo en Inglés | MEDLINE | ID: mdl-37289479

17.

Hepcidin-mediated hypoferremic response to acute inflammation requires a threshold of Bmp6/Hjv/Smad signaling.

Fillebeen, Carine; Wilkinson, Nicole; Charlebois, Edouard; Katsarou, Angeliki; Wagner, John; Pantopoulos, Kostas.

Blood ; 132(17): 1829-1841, 2018 10 25.

Artículo en Inglés | MEDLINE | ID: mdl-30213871

18.

Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a ß-thalassemia mouse model.

Garcia-Santos, Daniel; Hamdi, Amel; Saxova, Zuzana; Fillebeen, Carine; Pantopoulos, Kostas; Horvathova, Monika; Ponka, Prem.

Blood ; 131(2): 236-246, 2018 01 11.

Artículo en Inglés | MEDLINE | ID: mdl-29180398

19.

Regulatory Connections between Iron and Glucose Metabolism.

Fillebeen, Carine; Lam, Nhat Hung; Chow, Samantha; Botta, Amy; Sweeney, Gary; Pantopoulos, Kostas.

Int J Mol Sci ; 21(20)2020 Oct 21.

Artículo en Inglés | MEDLINE | ID: mdl-33096618

20.

Iron, FRDA, and intermediary metabolism.

Pantopoulos, Kostas.

Blood ; 137(15): 1994-1995, 2021 04 15.

Artículo en Inglés | MEDLINE | ID: mdl-33856446

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Excess of circulating apo-transferrin enhances dietary iron absorption.

Liver sinusoidal endothelial cells induce BMP6 expression in response to non-transferrin-bound iron.

The amino acid sensor GCN2 controls red blood cell clearance and iron metabolism through regulation of liver macrophages.

Oral iron supplementation: new formulations, old questions.

The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization.

Perturbations in lipid metabolism and gut microbiota composition precede cardiac dysfunction in a mouse model of thalassemia.

Iron Deficiency in Anemic Children Surviving Critical Illness: Post Hoc Analysis of a Single-Center Prospective Cohort in Canada, 2019-2022.

A Water-Soluble Chitosan Derivative for the Release of Bioactive Deferoxamine.

Phosphorus Overload Promotes Hepatic Lipolysis by Suppressing GSK3ß-Dependent Phosphorylation of PPARα at Ser84 and Thr265 in a Freshwater Teleost.

Iron increases lipid deposition via oxidative stress-mediated mitochondrial dysfunction and the HIF1α-PPARÎ³ pathway.

Genetic Iron Overload Hampers Development of Cutaneous Leishmaniasis in Mice.

Cardiac Hamp mRNA Is Predominantly Expressed in the Right Atrium and Does Not Respond to Iron.

Discovery-Based Proteomics Identify Skeletal Muscle Mitochondrial Alterations as an Early Metabolic Defect in a Mouse Model of ß-Thalassemia.

Human IRP1 Translocates to the Nucleus in a Cell-Specific and Iron-Dependent Manner.

Transferrin receptor 1 controls systemic iron homeostasis by fine-tuning hepcidin expression to hepatocellular iron load.

Macrophage checkpoint for iron absorption.

Hepcidin-mediated hypoferremic response to acute inflammation requires a threshold of Bmp6/Hjv/Smad signaling.

Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a ß-thalassemia mouse model.

Regulatory Connections between Iron and Glucose Metabolism.

Iron, FRDA, and intermediary metabolism.