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1.

BloodChIP Xtra: an expanded database of comparative genome-wide transcription factor binding and gene-expression profiles in healthy human stem/progenitor subsets and leukemic cells.

Thoms, Julie A I; Koch, Forrest C; Raei, Alireza; Subramanian, Shruthi; Wong, Jason W H; Vafaee, Fatemeh; Pimanda, John E.

Nucleic Acids Res ; 52(D1): D1131-D1137, 2024 Jan 05.

Artículo en Inglés | MEDLINE | ID: mdl-37870453

2.

Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy.

Liu, Yao-Chung; Kwon, Junsu; Fabiani, Emiliano; Xiao, Zhijian; Liu, Yanjing V; Follo, Matilde Y; Liu, Jinqin; Huang, Huijun; Gao, Chong; Liu, Jun; Falconi, Giulia; Valentini, Lia; Gurnari, Carmelo; Finelli, Carlo; Cocco, Lucio; Liu, Jin-Hwang; Jones, Adrianna I; Yang, Junyu; Yang, Henry; Thoms, Julie A I; Unnikrishnan, Ashwin; Pimanda, John E; Pan, Rongqing; Bassal, Mahmoud A; Voso, Maria T; Tenen, Daniel G; Chai, Li.

N Engl J Med ; 386(21): 1998-2010, 2022 05 26.

Artículo en Inglés | MEDLINE | ID: mdl-35613022

3.

Genome-wide transcription factor-binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs.

Subramanian, Shruthi; Thoms, Julie A I; Huang, Yizhou; Cornejo-Páramo, Paola; Koch, Forrest C; Jacquelin, Sebastien; Shen, Sylvie; Song, Emma; Joshi, Swapna; Brownlee, Chris; Woll, Petter S; Chacon-Fajardo, Diego; Beck, Dominik; Curtis, David J; Yehson, Kenneth; Antonenas, Vicki; O'Brien, Tracey; Trickett, Annette; Powell, Jason A; Lewis, Ian D; Pitson, Stuart M; Gandhi, Maher K; Lane, Steven W; Vafaee, Fatemeh; Wong, Emily S; Göttgens, Berthold; Alinejad-Rokny, Hamid; Wong, Jason W H; Pimanda, John E.

Blood ; 142(17): 1448-1462, 2023 10 26.

Artículo en Inglés | MEDLINE | ID: mdl-37595278

4.

Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy.

Schnegg-Kaufmann, Annatina S; Thoms, Julie A I; Bhuyan, Golam Sarower; Hampton, Henry R; Vaughan, Lachlin; Rutherford, Kayleigh; Kakadia, Purvi M; Lee, Hui Mei; Johansson, Emma M V; Failes, Timothy W; Arndt, Greg M; Koval, Jason; Lindeman, Robert; Warburton, Pauline; Rodriguez-Meira, Alba; Mead, Adam J; Unnikrishnan, Ashwin; Davidson, Sarah; Polizzotto, Mark N; Hertzberg, Mark; Papaemmanuil, Elli; Bohlander, Stefan K; Faridani, Omid R; Jolly, Christopher J; Zanini, Fabio; Pimanda, John E.

Blood ; 141(11): 1316-1321, 2023 03 16.

Artículo en Inglés | MEDLINE | ID: mdl-36493342

5.

p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion.

Kapeni, Chrysa; Nitsche, Leslie; Kilpatrick, Alastair M; Wilson, Nicola K; Xia, Kankan; Mirshekar-Syahkal, Bahar; Chandrakanthan, Vashe; Malouf, Camille; Pimanda, John E; Göttgens, Berthold; Kirschner, Kristina; Tomlinson, Simon R; Ottersbach, Katrin.

Blood ; 140(5): 464-477, 2022 08 04.

Artículo en Inglés | MEDLINE | ID: mdl-35653588

6.

Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a.

Shields, Benjamin J; Jackson, Jacob T; Metcalf, Donald; Shi, Wei; Huang, Qiutong; Garnham, Alexandra L; Glaser, Stefan P; Beck, Dominik; Pimanda, John E; Bogue, Clifford W; Smyth, Gordon K; Alexander, Warren S; McCormack, Matthew P.

Genes Dev ; 30(1): 78-91, 2016 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-26728554

7.

Analysing high-throughput sequencing data in Python with HTSeq 2.0.

Putri, Givanna H; Anders, Simon; Pyl, Paul Theodor; Pimanda, John E; Zanini, Fabio.

Bioinformatics ; 38(10): 2943-2945, 2022 05 13.

Artículo en Inglés | MEDLINE | ID: mdl-35561197

8.

Disruption of a GATA2-TAL1-ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells.

Thoms, Julie A I; Truong, Peter; Subramanian, Shruthi; Knezevic, Kathy; Harvey, Gregory; Huang, Yizhou; Seneviratne, Janith A; Carter, Daniel R; Joshi, Swapna; Skhinas, Joanna; Chacon, Diego; Shah, Anushi; de Jong, Ineke; Beck, Dominik; Göttgens, Berthold; Larsson, Jonas; Wong, Jason W H; Zanini, Fabio; Pimanda, John E.

Blood ; 138(16): 1441-1455, 2021 10 21.

Artículo en Inglés | MEDLINE | ID: mdl-34075404

9.

Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys.

Lee, Quintin; Padula, Matthew P; Pinello, Natalia; Williams, Simon H; O'Rourke, Matthew B; Fumagalli, Marcilio Jorge; Orkin, Joseph D; Song, Renhua; Shaban, Babak; Brenner, Ori; Pimanda, John E; Weninger, Wolfgang; Souza, William Marciel de; Melin, Amanda D; Wong, Justin J-L; Crim, Marcus J; Monette, Sébastien; Roediger, Ben; Jolly, Christopher J.

PLoS Pathog ; 16(1): e1008262, 2020 01.

Artículo en Inglés | MEDLINE | ID: mdl-31971979

10.

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1.

Carmichael, Catherine L; Wang, Jueqiong; Nguyen, Thao; Kolawole, Oluseyi; Benyoucef, Aissa; De Mazière, Charlotte; Milne, Anna R; Samuel, Sona; Gillinder, Kevin; Hediyeh-Zadeh, Soroor; Vo, Anh N Q; Huang, Yizhou; Knezevic, Kathy; McInnes, William R L; Shields, Benjamin J; Mitchell, Helen; Ritchie, Matthew E; Lammens, Tim; Lintermans, Beatrice; Van Vlierberghe, Pieter; Wong, Nicholas C; Haigh, Katharina; Thoms, Julie A I; Toulmin, Emma; Curtis, David J; Oxley, Ethan P; Dickins, Ross A; Beck, Dominik; Perkins, Andrew; McCormack, Matthew P; Davis, Melissa J; Berx, Geert; Zuber, Johannes; Pimanda, John E; Kile, Benjamin T; Goossens, Steven; Haigh, Jody J.

Blood ; 136(8): 957-973, 2020 08 20.

Artículo en Inglés | MEDLINE | ID: mdl-32369597

11.

Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes.

Perera, Dilmi; Poulos, Rebecca C; Shah, Anushi; Beck, Dominik; Pimanda, John E; Wong, Jason W H.

Nature ; 532(7598): 259-63, 2016 Apr 14.

Artículo en Inglés | MEDLINE | ID: mdl-27075100

12.

A novel role for Lyl1 in primitive erythropoiesis.

Chiu, Sung K; Saw, Jesslyn; Huang, Yizhou; Sonderegger, Stefan E; Wong, Nicholas C; Powell, David R; Beck, Dominic; Pimanda, John E; Tremblay, Cedric S; Curtis, David J.

Development ; 145(19)2018 10 11.

Artículo en Inglés | MEDLINE | ID: mdl-30185409

13.

Label-Free Isolation and Single Cell Biophysical Phenotyping Analysis of Primary Cardiomyocytes Using Inertial Microfluidics.

Tavassoli, Hossein; Rorimpandey, Prunella; Kang, Young Chan; Carnell, Michael; Brownlee, Chris; Pimanda, John E; Chan, Peggy P Y; Chandrakanthan, Vashe.

Small ; 17(8): e2006176, 2021 02.

Artículo en Inglés | MEDLINE | ID: mdl-33369875

14.

Shared roles for Scl and Lyl1 in murine platelet production and function.

Chiu, Sung K; Orive, Stephanie L; Moon, Mitchell J; Saw, Jesslyn; Ellis, Sarah; Kile, Benjamin T; Huang, Yizhou; Chacon, Diego; Pimanda, John E; Beck, Dominik; Hamilton, Justin R; Tremblay, Cedric S; Curtis, David J.

Blood ; 134(10): 826-835, 2019 09 05.

Artículo en Inglés | MEDLINE | ID: mdl-31300405

15.

DDX41: the poster child for familial MDS/AML grows up.

Truong, Peter; Pimanda, John E.

Blood ; 141(5): 447-449, 2023 02 02.

Artículo en Inglés | MEDLINE | ID: mdl-36729548

16.

Srsf2^P95H initiates myeloid bias and myelodysplastic/myeloproliferative syndrome from hemopoietic stem cells.

Smeets, Monique F; Tan, Shuh Ying; Xu, Jane Jialu; Anande, Govardhan; Unnikrishnan, Ashwin; Chalk, Alistair M; Taylor, Scott R; Pimanda, John E; Wall, Meaghan; Purton, Louise E; Walkley, Carl R.

Blood ; 132(6): 608-621, 2018 08 09.

Artículo en Inglés | MEDLINE | ID: mdl-29903888

17.

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation.

Jacquelin, Sebastien; Straube, Jasmin; Cooper, Leanne; Vu, Therese; Song, Axia; Bywater, Megan; Baxter, Eva; Heidecker, Matthew; Wackrow, Brad; Porter, Amy; Ling, Victoria; Green, Joanne; Austin, Rebecca; Kazakoff, Stephen; Waddell, Nicola; Hesson, Luke B; Pimanda, John E; Stegelmann, Frank; Bullinger, Lars; Döhner, Konstanze; Rampal, Raajit K; Heckl, Dirk; Hill, Geoffrey R; Lane, Steven W.

Blood ; 132(26): 2707-2721, 2018 12 27.

Artículo en Inglés | MEDLINE | ID: mdl-30366920

18.

DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts.

Richards, Laura A; Kumari, Ashu; Knezevic, Kathy; Thoms, Julie Ai; von Jonquieres, Georg; Napier, Christine E; Ali, Zara; O'Brien, Rosemary; Marks-Bluth, Jonathon; Maritz, Michelle F; Pickett, Hilda A; Morris, Jonathan; Pimanda, John E; MacKenzie, Karen L.

Haematologica ; 105(6): 1517-1526, 2020 06.

Artículo en Inglés | MEDLINE | ID: mdl-31413099

19.

Transcriptional networks in acute myeloid leukemia.

Thoms, Julie A I; Beck, Dominik; Pimanda, John E.

Genes Chromosomes Cancer ; 58(12): 859-874, 2019 12.

Artículo en Inglés | MEDLINE | ID: mdl-31369171

20.

PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells.

Chandrakanthan, Vashe; Yeola, Avani; Kwan, Jair C; Oliver, Rema A; Qiao, Qiao; Kang, Young Chan; Zarzour, Peter; Beck, Dominik; Boelen, Lies; Unnikrishnan, Ashwin; Villanueva, Jeanette E; Nunez, Andrea C; Knezevic, Kathy; Palu, Cintia; Nasrallah, Rabab; Carnell, Michael; Macmillan, Alex; Whan, Renee; Yu, Yan; Hardy, Philip; Grey, Shane T; Gladbach, Amadeus; Delerue, Fabien; Ittner, Lars; Mobbs, Ralph; Walkley, Carl R; Purton, Louise E; Ward, Robyn L; Wong, Jason W H; Hesson, Luke B; Walsh, William; Pimanda, John E.

Proc Natl Acad Sci U S A ; 113(16): E2306-15, 2016 Apr 19.

Artículo en Inglés | MEDLINE | ID: mdl-27044077

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