A large outbreak of giardiasis in a municipality of the Bologna province, north-eastern Italy, November 2018 to April 2019.

Giardiasis, the disease caused by the flagellate Giardia duodenalis (syn. G.lamblia, G. intestinalis), is the most commonly reported among the five food- and waterborne parasitic diseases under mandatory surveillance in 24 EU countries. From November 2018 to April 2019, an outbreak of giardiasis occurred in a municipality of the Bologna province, in north-eastern Italy. Microscopy and immunochromatography identified cysts and antigens, respectively, of the parasite in stool samples of 228 individuals. Molecular typing of 136 stool samples revealed a vast predominance (95%) of G. duodenalis assemblage B. Investigations into potential sources indicated tap water as the most likely vehicle of infection, although cysts were not detected in water samples. Control measures mostly aimed at preventing secondary transmission by informing citizens about the outbreak, and by treatment of patients with anti-parasitic drugs. This is the first documented human outbreak of giardiasis in Italy; its investigation has highlighted the difficulties in the timely detection and management of this parasite, which is often overlooked as a cause of human gastroenteritis. The long and variable incubation time, absence of specific symptoms and a general lack of awareness about this pathogen contributed to delay in diagnosis.

Hospitalizations for pertussis in Italy, 1999-2009: analysis of the hospital discharge database.

Even if the incidence of pertussis has greatly decreased after the adoption of immunization, it still remains a relevant cause of death in infants in their first years of life. At national level, data are usually greatly underestimated. The objective of this study was to retrospectively review the national hospital discharge form database. The national database was retrospectively searched using the International Classification of Diseases, ninth revision, Clinical Modification system. In the period 1999-2009, 7,768 hospitalizations for pertussis (primary diagnosis) have been registered: 6,971 hospitalizations and 797 day hospital admissions. The annual mean was equal to 633.6 hospitalizations and 72.4 day hospital admissions. The majority of hospitalizations (57.4 %) involved subjects <1 year of age; the mean duration of stay was about 6 days. Conclusion These data, even if restricted to hospitalizations registered at national level, confirm the epidemiological impact of pertussis and its complications in a country with a consistently high vaccination coverage rate.