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1.
Nervenarzt ; 95(4): 342-352, 2024 Apr.
Artículo en Alemán | MEDLINE | ID: mdl-38277047

RESUMEN

The number of tracheotomized patients with dysphagia and their need for treatment are continuously increasing in clinical and community settings. The revised version of the directive on home care and community-based intensive care of the Federal Joint Committee (G-BA) requires that tracheotomized patients are regularly evaluated with the aim of identifying and promoting the therapeutic potential after hospital discharge. Dysphagia treatment plays a crucial role as without improvement of severe dysphagia there is practically no possibility for decannulation. Tracheotomized patients with dysphagia are treated by speech and language therapists (SLT); however, the contents of tracheostomy management (TM) are not obligatory in the speech and language therapeutic training curricula, so that there is a need for further education and treatment standards must be secured. Therefore, the German Interdisciplinary Society for Dysphagia (DGD) in cooperation with the participating German medical and therapeutic societies developed a postgraduate curriculum for TM. This should serve as the basis for contents in TM and qualification of therapists within the framework of the delegation of medical services. The goals of the TM curriculum are the definition of theoretical and practical contents of TM, the qualification to perform TM according to current standards of care and quality assurance. The curriculum defines two qualification levels (user and trainer), entry requirements, curricular contents, examination and qualification criteria as well as transitional regulations for SLTs already experienced in TM.


Asunto(s)
Trastornos de Deglución , Servicios de Atención de Salud a Domicilio , Humanos , Trastornos de Deglución/diagnóstico , Trastornos de Deglución/cirugía , Traqueostomía , Curriculum , Terapia del Lenguaje , Logopedia
2.
HNO ; 72(6): 393-404, 2024 Jun.
Artículo en Alemán | MEDLINE | ID: mdl-38578463

RESUMEN

The number of tracheotomized patients with dysphagia and their need for treatment are continuously increasing in clinical and community settings. The revised version of the directive on home care and community-based intensive care of the Federal Joint Committee (G-BA) requires that tracheotomized patients are regularly evaluated with the aim of identifying and promoting the therapeutic potential after hospital discharge. Dysphagia treatment plays a crucial role as without improvement of severe dysphagia there is practically no possibility for decannulation. Tracheotomized patients with dysphagia are treated by speech and language therapists (SLT); however, the contents of tracheostomy management (TM) are not obligatory in the speech and language therapeutic training curricula, so that there is a need for further education and treatment standards must be secured. Therefore, the German Interdisciplinary Society for Dysphagia (DGD) in cooperation with the participating German medical and therapeutic societies developed a postgraduate curriculum for TM. This should serve as the basis for contents in TM and qualification of therapists within the framework of the delegation of medical services. The goals of the TM curriculum are the definition of theoretical and practical contents of TM, the qualification to perform TM according to current standards of care and quality assurance. The curriculum defines two qualification levels (user and trainer), entry requirements, curricular contents, examination and qualification criteria as well as transitional regulations for SLTs already experienced in TM.


Asunto(s)
Curriculum , Trastornos de Deglución , Traqueostomía , Trastornos de Deglución/rehabilitación , Trastornos de Deglución/terapia , Trastornos de Deglución/etiología , Trastornos de Deglución/diagnóstico , Humanos , Alemania , Traqueostomía/educación , Traqueostomía/normas , Logopedia/normas , Logopedia/métodos , Patología del Habla y Lenguaje/educación , Patología del Habla y Lenguaje/normas , Guías de Práctica Clínica como Asunto
3.
Pneumologie ; 76(12): 855-907, 2022 Dec.
Artículo en Alemán | MEDLINE | ID: mdl-36479679

RESUMEN

The German Society of Pneumology initiated 2021 the AWMF S1 guideline Long COVID/Post-COVID. In a broad interdisciplinary approach, this S1 guideline was designed based on the current state of knowledge.The clinical recommendations describe current Long COVID/Post-COVID symptoms, diagnostic approaches, and therapies.In addition to the general and consensus introduction, a subject-specific approach was taken to summarize the current state of knowledge.The guideline has an explicit practical claim and will be developed and adapted by the author team based on the current increase in knowledge.


Asunto(s)
COVID-19 , Síndrome Post Agudo de COVID-19 , Humanos
4.
Nature ; 528(7581): 237-40, 2015 Dec 10.
Artículo en Inglés | MEDLINE | ID: mdl-26659183

RESUMEN

The dwarf planet (1) Ceres, the largest object in the main asteroid belt with a mean diameter of about 950 kilometres, is located at a mean distance from the Sun of about 2.8 astronomical units (one astronomical unit is the Earth-Sun distance). Thermal evolution models suggest that it is a differentiated body with potential geological activity. Unlike on the icy satellites of Jupiter and Saturn, where tidal forces are responsible for spewing briny water into space, no tidal forces are acting on Ceres. In the absence of such forces, most objects in the main asteroid belt are expected to be geologically inert. The recent discovery of water vapour absorption near Ceres and previous detection of bound water and OH near and on Ceres (refs 5-7) have raised interest in the possible presence of surface ice. Here we report the presence of localized bright areas on Ceres from an orbiting imager. These unusual areas are consistent with hydrated magnesium sulfates mixed with dark background material, although other compositions are possible. Of particular interest is a bright pit on the floor of crater Occator that exhibits probable sublimation of water ice, producing haze clouds inside the crater that appear and disappear with a diurnal rhythm. Slow-moving condensed-ice or dust particles may explain this haze. We conclude that Ceres must have accreted material from beyond the 'snow line', which is the distance from the Sun at which water molecules condense.

5.
BMC Neurol ; 17(1): 53, 2017 Mar 20.
Artículo en Inglés | MEDLINE | ID: mdl-28320357

RESUMEN

BACKGROUND: Colonization or infection with multi-drug resistant (MDR) bacteria is considered detrimental to the outcome of neurological and neurosurgical early rehabilitation patients. METHODS: In a German multi-center study, 754 neurological early rehabilitation patients were enrolled and and reviewed in respect to MDR status, length of stay (LOS) and the following outcome variables: Barthel Index (BI), Early Rehabilitation Index (ERI), Glasgow Outcome Score Extended (GOSE), Coma Remission Scale (CRS), Functional Ambulation Categories (FAC). RESULTS: The mean age of the study population was 68.0 ± 14.8 years. Upon admission, the following prevalence for MDRs was observed: MRSA (methicillin resistant staphylococcus aureus) 7.0% (53/754), ESBL- (extended spectrum beta-lactamase) producing bacteria strains 12.6% (95/754), VRE (vancomycin resistant enterococci) 2.8% (21/754). Patients colonized or infected with MDR bacteria (MDR+) were significantly more frequently diagnosed with a critical illness polyneuropathy - CIP - than non-colonized (MDR-) patients: 29.0% vs. 14.8%. In addition, they were more frequently mechanically ventilated (MDR+: 55/138, 39.9%; MDR- 137/616, 22.2%). MDR+ patients were referred to rehabilitation earlier, had a longer LOS in early rehabilitation, lower BI on admission and at discharge, lower ERI on admission and lower CRS at discharge than MDR- patients. There was a highly significant correlation of the BI upon admission with the BI at discharge (rs = 0.492, p < 0.001). GOSE at discharge differed significantly between both groups (χ 2-test, p < 0.01). Perhaps of greatest importance, mortality among MDR+ was higher in comparison to MDR- (18.1% vs. 7.6%). CONCLUSIONS: The outcome of neurological early rehabilitation patients colonized or infected with MDR bacteria including MRSA or ESBL producing strains is significantly poorer than by non-colonized patients. There is some evidence that the poor outcome could be related to the higher morbidity and lower functional status upon admission.


Asunto(s)
Infecciones Bacterianas/rehabilitación , Farmacorresistencia Bacteriana Múltiple , Intervención Médica Temprana/métodos , Hospitalización/estadística & datos numéricos , Enfermedades del Sistema Nervioso/rehabilitación , Rehabilitación Neurológica/métodos , Evaluación de Resultado en la Atención de Salud , Anciano , Anciano de 80 o más Años , Infecciones Bacterianas/epidemiología , Comorbilidad , Femenino , Alemania/epidemiología , Humanos , Masculino , Persona de Mediana Edad , Enfermedades del Sistema Nervioso/epidemiología
6.
Geophys Res Lett ; 44(13): 6570-6578, 2017 07 16.
Artículo en Inglés | MEDLINE | ID: mdl-28989206

RESUMEN

Prior to the arrival of the Dawn spacecraft at Ceres, the dwarf planet was anticipated to be ice-rich. Searches for morphological features related to ice have been ongoing during Dawn's mission at Ceres. Here we report the identification of pitted terrains associated with fresh Cerean impact craters. The Cerean pitted terrains exhibit strong morphological similarities to pitted materials previously identified on Mars (where ice is implicated in pit development) and Vesta (where the presence of ice is debated). We employ numerical models to investigate the formation of pitted materials on Ceres and discuss the relative importance of water ice and other volatiles in pit development there. We conclude that water ice likely plays an important role in pit development on Ceres. Similar pitted terrains may be common in the asteroid belt and may be of interest to future missions motivated by both astrobiology and in situ resource utilization.

7.
Rehabilitation (Stuttg) ; 56(5): 328-336, 2017 Oct.
Artículo en Alemán | MEDLINE | ID: mdl-28476068

RESUMEN

In Germany, medical-occupational rehabilitation represents an essential link between rehabilitation programs focusing either on medical or occupational rehabilitation. Its main objective is return to work. The current study presents the vocational integration 5 years after medical-occupational rehabilitation and determines possible prognostic factors for long-term occupational integration. To evaluate the effectiveness of medical-occupational rehabilitation, a 5-year-follow-up interview was conducted with participants (n=105) of the multicenter study on medical-occupational rehabilitation (MEmbeR). As a main result, 76% of the participants were still employed 5 years after medical-occupational rehabilitation and the return to work rate was 57%. Prognostic factors for long-term occupational integration could not be identified. However, a low degree of disability, an unrestricted capacity for teamwork as well as an unrestricted ability to judge might be beneficial factors for a successful reintegration. The high amount of participants who returned to work 5 years after medical-occupational rehabilitation, supports the concept of medical-occupational rehabilitation. However, more studies are needed to identify further factors influencing the outcome.


Asunto(s)
Enfermedades Profesionales/rehabilitación , Rehabilitación Vocacional , Resultado del Tratamiento , Adolescente , Adulto , Evaluación de la Discapacidad , Femenino , Estudios de Seguimiento , Alemania , Humanos , Comunicación Interdisciplinaria , Colaboración Intersectorial , Masculino , Persona de Mediana Edad , Pronóstico , Reinserción al Trabajo/estadística & datos numéricos , Adulto Joven
8.
Nervenarzt ; 88(6): 652-674, 2017 Jun.
Artículo en Alemán | MEDLINE | ID: mdl-28484823

RESUMEN

Prolonged weaning of patients with neurological or neurosurgery disorders is associated with specific characteristics, which are taken into account by the German Society for Neurorehabilitation (DGNR) in its own guideline. The current S2k guideline of the German Society for Pneumology and Respiratory Medicine is referred to explicitly with regard to definitions (e.g., weaning and weaning failure), weaning categories, pathophysiology of weaning failure, and general weaning strategies. In early neurological and neurosurgery rehabilitation, patients with central of respiratory regulation disturbances (e.g., cerebral stem lesions), swallowing disturbances (neurogenic dysphagia), neuromuscular problems (e.g., critical illness polyneuropathy, Guillain-Barre syndrome, paraplegia, Myasthenia gravis) and/or cognitive disturbances (e.g., disturbed consciousness and vigilance disorders, severe communication disorders), whose care during the weaning of ventilation requires, in addition to intensive medical competence, neurological or neurosurgical and neurorehabilitation expertise. In Germany, this competence is present in centers of early neurological and neurosurgery rehabilitation, as a hospital treatment. The guideline is based on a systematic search of guideline databases and MEDLINE. Consensus was established by means of a nominal group process and Delphi procedure moderated by the Association of the Scientific Medical Societies in Germany (AWMF). In the present guideline of the DGNR, the special structural and substantive characteristics of early neurological and neurosurgery rehabilitation and existing studies on weaning in early rehabilitation facilities are examined.Addressees of the guideline are neurologists, neurosurgeons, anesthesiologists, palliative physicians, speech therapists, intensive care staff, ergotherapists, physiotherapists, and neuropsychologists. In addition, this guideline is intended to provide information to specialists for physical medicine and rehabilitation (PMR), pneumologists, internists, respiratory therapists, the German Medical Service of Health Insurance Funds (MDK) and the German Association of Health Insurance Funds (MDS). The main goal of this guideline is to convey the current knowledge on the subject of "Prolonged weaning in early neurological and neurosurgery rehabilitation".


Asunto(s)
Enfermedades del Sistema Nervioso/rehabilitación , Rehabilitación Neurológica/normas , Procedimientos Neuroquirúrgicos/rehabilitación , Procedimientos Neuroquirúrgicos/normas , Guías de Práctica Clínica como Asunto , Insuficiencia Respiratoria/prevención & control , Desconexión del Ventilador/normas , Alemania/epidemiología , Humanos , Enfermedades del Sistema Nervioso/cirugía , Desconexión del Ventilador/métodos
9.
Nervenarzt ; 87(10): 1057-1061, 2016 Oct.
Artículo en Alemán | MEDLINE | ID: mdl-27531207

RESUMEN

BACKGROUND: Arm paralysis after a stroke is a major cause of impairment. OBJECTIVE: Presentation of therapeutic options and the efficacy in arm rehabilitation after stroke. MATERIAL AND METHODS: Based on a systematic critical appraisal of randomized controlled trials (RCT) the therapeutic procedures for arm paralysis after stroke in the context of their effectiveness are introduced, including robotic therapy, mirror therapy, constraint-induced movement therapy (CIMT), arm basis training, arm ability training, neuromuscular electrical stimulation, bilateral and task-specific training, mental training and transcranial stimulation techniques, such as repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS). RESULTS AND DISCUSSION: Several therapeutic procedures with proven efficacy are currently available for arm rehabilitation after stroke. Their differential indications are presented and associated with conclusions for clinical practice.


Asunto(s)
Trastornos del Movimiento/rehabilitación , Modalidades de Fisioterapia , Robótica/métodos , Rehabilitación de Accidente Cerebrovascular/métodos , Brazo , Medicina Basada en la Evidencia , Humanos , Trastornos del Movimiento/diagnóstico , Evaluación de Resultado en la Atención de Salud/métodos , Recuperación de la Función , Resultado del Tratamiento
10.
Nervenarzt ; 87(6): 634-44, 2016 Jun.
Artículo en Alemán | MEDLINE | ID: mdl-27090897

RESUMEN

BACKGROUND: In Germany, neurological-neurosurgical early rehabilitation is well established in the treatment of severe neurological diseases. To develop quality standards, knowledge of the current rehabilitation course is required. PATIENTS AND METHODS: A retrospective analysis was performed on the course of rehabilitation from patients in an early neurological/neurosurgical rehabilitation program in 16 centers from 10 German states. The odds for a good or poor outcome were investigated using a multivariate logistic regression model. RESULTS: Seven hundred and fifty-four patients were included in the study. The average age of the patients was 68 ± 15 years. Of the patients studied, 26 % were on mechanical ventilation commencing their neurological rehabilitation. The average duration of stay was 56 ± 51 days. Weaning rate from mechanical ventilation was 65 % and the rate of weaning from tracheal cannula was 54 %. Mean improvement in the Barthel Index of 17 points, significant reduction of dysphagia (from 62 to 30 %) and depended walking (from 99 to 82 %), and the achievement of phase C (the next stage of rehabilitation) in 38 % can still be counted as signs of successful rehabilitation. During their course of stay, near 10 % of the patients died. Of these, 67 % received solely palliative care. In the multivariate logistic models, the absence of the factor "necessity for mechanical ventilation on admission" (odds ratio 0.61; 95 % confidence interval (CI): 0.42 … 0.89) increased the chance for good outcome and the presence of this factor the risk of dying with an odds ratio of 8.07 (95 % CI: 4.54-14.34). DISCUSSION: In spite of the severity of neurological deficits, significant functional progress has been made. These results could be interpret as positive proof of the efficacy of neurological/neurosurgical early rehabilitation programs.


Asunto(s)
Enfermedades del Sistema Nervioso/rehabilitación , Rehabilitación Neurológica/métodos , Procedimientos Neuroquirúrgicos/rehabilitación , Anciano , Anciano de 80 o más Años , Evaluación de la Discapacidad , Femenino , Alemania , Humanos , Tiempo de Internación/estadística & datos numéricos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Enfermedades del Sistema Nervioso/mortalidad , Procedimientos Neuroquirúrgicos/mortalidad , Estudios Retrospectivos , Resultado del Tratamiento , Desconexión del Ventilador
11.
Rehabilitation (Stuttg) ; 53(2): 87-93, 2014 Apr.
Artículo en Alemán | MEDLINE | ID: mdl-24254520

RESUMEN

INTRODUCTION: MEmbeR is a prospective multi-center study on medical-occupational rehabilitation in Germany. METHODS: 196 neurological, psychiatric, orthopaedic, and internal medicine patients from 21 rehabilitation centres all across Germany have been enrolled and followed-up for 2 years after discharge. Primary outcome parameter was defined as return to work. Further, the SF-12 and a Mini-ICF-Rating have been used. RESULTS: Mean age was 34.1 (9.9) years, length of stay 150.0 (223.5) days. Prior to occupational rehabilitation, 69.9% were unable to work, 2 years after discharge only 5.6%. Rate of participants seeking a job was reduced from 19.7% to 3.1%. In summary, 78.1% returned to work. Employed participants were younger (32.8 [9.7] vs. 38.5 [9.4] years, p=0.001) and less disabled (Degree of Disablement [GdB]: 20.0 [31.2] vs. 36.1 [33.7], p<0.05). CONCLUSION: The multicenter cohort study MEmbeR provides further knowledge about the outcome of medical-occupational rehabilitation in Germany.


Asunto(s)
Personas con Discapacidad/rehabilitación , Personas con Discapacidad/estadística & datos numéricos , Tiempo de Internación/estadística & datos numéricos , Terapia Ocupacional/estadística & datos numéricos , Centros de Rehabilitación/estadística & datos numéricos , Reinserción al Trabajo/estadística & datos numéricos , Desempleo/estadística & datos numéricos , Adolescente , Adulto , Femenino , Alemania/epidemiología , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Rehabilitación Vocacional , Resultado del Tratamiento , Revisión de Utilización de Recursos , Adulto Joven
12.
Skeletal Radiol ; 41(1): 61-6, 2012 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-21331512

RESUMEN

OBJECTIVE: To retrospectively evaluate neurogenic heterotopic ossification in an early neurological rehabilitation population (phases B and C) with respect to epidemiology and morphology on conventional radiographs. MATERIALS AND METHODS: Over a 4-year period, 1,463 patients treated at a clinic for early neurological rehabilitation were evaluated for clinical symptoms of neurogenic heterotopic ossification. In case of clinical suspicion, plain radiographs of the expected sites were obtained. If heterotopic ossification was detected, the initial and subsequent radiographs were retrospectively analyzed for sites, size, and morphology. Immature lesions were categorized as small (<10 mm) or large (10-100 mm). RESULTS: The prevalence rate of neurogenic heterotopic ossification was 2.05%. The condition was most common in young male adults. The hip was the most common site accounting for more than half of the cases. Two or more ossifications were seen in 56.7% of the affected patients with approximately two-thirds showing bilateral symmetric involvement of corresponding joint regions. The size of ossifications strongly varied interindividually. Small immature lesions demonstrated less progression in size than large lesions during maturation (P < 0.05). CONCLUSION: Standard radiographs, as a fast and inexpensive technique, allow the expected size progression of heterotopic ossifications during maturation to be estimated, which is relevant in terms of therapeutic decisions, patient mobilization, and neurological rehabilitation.


Asunto(s)
Enfermedades del Sistema Nervioso/diagnóstico por imagen , Enfermedades del Sistema Nervioso/epidemiología , Osificación Heterotópica/diagnóstico por imagen , Osificación Heterotópica/epidemiología , Adolescente , Adulto , Anciano , Causalidad , Comorbilidad , Femenino , Alemania/epidemiología , Humanos , Masculino , Persona de Mediana Edad , Enfermedades del Sistema Nervioso/rehabilitación , Osificación Heterotópica/rehabilitación , Prevalencia , Radiografía , Medición de Riesgo , Factores de Riesgo , Resultado del Tratamiento
13.
Nervenarzt ; 83(10): 1300-7, 2012 Oct.
Artículo en Alemán | MEDLINE | ID: mdl-22814635

RESUMEN

BACKGROUND: A significant proportion of patients with long-term mechanical ventilation (MV) and difficult or prolonged weaning suffer from primary or secondary neurological conditions and concomitant functional disorders, in addition to respiratory problems. Therefore, these patients are treated in neurological weaning departments. MATERIAL AND METHODS: Using a questionnaire members of the German Working Group for early neurorehabilitation were interviewed with respect to the structure of weaning facilities, weaning strategies, patient characteristics and treatment outcome of patients admitted for weaning in 2009. RESULTS: In the year 2009 a total of 1,486 patients were admitted to 7 participating neurological weaning units. The primary diagnosis was a neurological condition in 97.5% of the patients. In 62.9% of the patients the neurological condition was considered to be primarily responsible for the MV, 22.8% demonstrated pulmonary factors and for 3.0% a cardiac condition was determined to be decisive. In 5.0% of the patients it was not possible to ascertain a single cause or factor. Weaning was successful in 69.8% of all cases, 64.9% (965 patients) were released from the facility without MV, 274 patients (18.4%) were released with MV, 61.3% of these (168 patients) were referred to other rehabilitation facilities or into the care of the family physician and 38.7% (106 patients) were transferred to other hospitals due to special medical problems. The total mortality rate was 16.6% (247 patients deceased). CONCLUSIONS: In this first comprehensive evaluation of German neurological weaning centers for patients with long-term MV, structures and treatment outcomes were compared with recent results from the literature.


Asunto(s)
Enfermedades del Sistema Nervioso/epidemiología , Enfermedades del Sistema Nervioso/rehabilitación , Trastornos Respiratorios/epidemiología , Trastornos Respiratorios/rehabilitación , Desconexión del Ventilador/estadística & datos numéricos , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Preescolar , Enfermedad Crónica , Comorbilidad , Femenino , Alemania , Humanos , Masculino , Persona de Mediana Edad , Prevalencia , Medición de Riesgo , Encuestas y Cuestionarios , Resultado del Tratamiento , Adulto Joven
14.
Neuroimage Clin ; 35: 103093, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35772193

RESUMEN

Sensorimotor representations of swallowing in pre- and postcentral gyri of both cerebral hemispheres are interconnected by callosal tracts. We were interested in (1) the callosal location of fibers interconnecting the precentral gyri (with the primary motor cortex; M1) and the postcentral gyri (with the primary somatosensory cortex; S1) relevant for swallowing, and (2) the importance of their integrity given the challenges of swallowing compliance after recovery of dysphagia following stroke. We investigated 17 patients who had almost recovered from dysphagia in the chronic stage following stroke and age-matched and gender-matched healthy controls. We assessed their swallowing compliance, investigating swallowing of a predefined bolus in one swallowing movement in response to a 'go' signal when in a lying position. A somatotopic representation of swallowing was mapped for the pre- and postcentral gyrus, and callosal tract location between these regions was compared to results for healthy participants. We applied multi-directional diffusion-weighted imaging of the brain in patients and matched controls to calculate fractional anisotropy (FA) as a tract integrity marker for M1/S1 callosal fibers. Firstly, interconnecting callosal tract maps were well spatially separated for M1 and S1, but were overlapped for somatotopic differentiation within M1 and S1 in healthy participants' data (HCP: head/face representation; in house dataset: fMRI-swallowing representation in healthy volunteers). Secondly, the FA for both callosal tracts, connecting M1 and S1 swallowing representations, were decreased for patients when compared to healthy volunteers. Thirdly, integrity of callosal fibers interconnecting S1 swallowing representation sites was associated with effective swallowing compliance. We conclude that somatosensory interaction between hemispheres is important for effective swallowing in the case of a demanding task undertaken by stroke survivors with good swallowing outcome from dysphagia.


Asunto(s)
Trastornos de Deglución , Accidente Cerebrovascular , Sustancia Blanca , Deglución/fisiología , Trastornos de Deglución/diagnóstico por imagen , Trastornos de Deglución/etiología , Imagen de Difusión Tensora/métodos , Humanos , Accidente Cerebrovascular/complicaciones , Accidente Cerebrovascular/diagnóstico por imagen , Sustancia Blanca/diagnóstico por imagen
15.
Acta Neurol Scand ; 119(2): 81-7, 2009 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-18638038

RESUMEN

BACKGROUND: Different workers have reported racial disparities in the distribution of risk factors for stroke and stroke subtype (ischemic vs hemorrhagic). No transcultural transnational studies have been conducted to confirm and relate these disparities to one another. Our objective was to identify differences in the distribution of risk factors for stroke and stroke subtypes among urban-dwelling stroke patients in Nigeria, a developing country, and Germany, an industrialized country. METHODS: Consecutive stroke patients in Ibadan (100) and Berlin (103) were studied. Their hospital records were screened to identify documented vascular risk factors and stroke subtype. RESULTS: The stroke patients in Ibadan were younger than those in Berlin (t = 4.940, P = 0.000). Hypertension was significantly more common in Ibadan while cigarette smoking, dyslipidemia, atherosclerosis, and cardiac factors were significantly more frequent in Berlin. Cerebral infarction was more common in Berlin (80%) than in Ibadan (63%). CONCLUSION: The risk factors associated with cerebral infarction were more frequent in Berlin. We suspect that racial disparity in risk factors for stroke may account for the difference in proportions of stroke subtype in black and white populations. Larger prospective community-based multinational multiracial studies are required to confirm these disparities and identify possible underlying genetic, dietary, and socio-economic factors.


Asunto(s)
Población Negra , Accidente Cerebrovascular/etnología , Población Blanca , Adulto , Anciano , Anciano de 80 o más Años , Aterosclerosis/epidemiología , Aterosclerosis/etnología , Berlin/epidemiología , Berlin/etnología , Infarto Cerebral/epidemiología , Infarto Cerebral/etnología , Demografía , Dislipidemias/epidemiología , Dislipidemias/etnología , Femenino , Humanos , Hipertensión/epidemiología , Hipertensión/etnología , Masculino , Persona de Mediana Edad , Nigeria/epidemiología , Nigeria/etnología , Proyectos Piloto , Estudios Retrospectivos , Factores de Riesgo , Fumar/epidemiología , Fumar/etnología , Accidente Cerebrovascular/epidemiología , Accidente Cerebrovascular/etiología
16.
J Geophys Res Planets ; 124(12): 3329-3343, 2019 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-32355585

RESUMEN

Landslides are among the most widespread geologic features on Ceres. Using data from Dawn's Framing Camera, landslides were previously classified based upon geomorphologic characteristics into one of three archetypal categories, Type 1(T1), Type 2 (T2), and Type 3 (T3). Due to their geologic context, variation in age, and physical characteristics, most landslides on Ceres are, however, intermediate in their morphology and physical properties between the archetypes of each landslide class. Here we describe the varied morphology of individual intermediate landslides, identify geologic controls that contribute to this variation, and provide first-order quantification of the physical properties of the continuum of Ceres's surface flows. These intermediate flows appear in varied settings and show a range of characteristics, including those found at contacts between craters, those having multiple trunks or lobes; showing characteristics of both T2 and T3 landslides; material slumping on crater rims; very small, ejecta-like flows; and those appearing inside of catenae. We suggest that while their morphologies can vary, the distribution and mechanical properties of intermediate landslides do not differ significantly from that of archetypal landslides, confirming a link between landslides and subsurface ice. We also find that most intermediate landslides are similar to Type 2 landslides and formed by shallow failure. Clusters of these features suggest ice enhancement near Juling, Kupalo and Urvara craters. Since the majority of Ceres's landslides fall in the intermediate landslide category, placing their attributes in context contributes to a better understanding of Ceres's shallow subsurface and the nature of ground ice.

17.
Eur J Neurol ; 15(6): 627-33, 2008 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-18474078

RESUMEN

BACKGROUND AND PURPOSE: National Institutes of Health Stroke Scale (NIHSS) is long and complex. Our objective was to design a valid, reliable, simple, and time-saving stroke severity scale. METHODS: About 103 and 100 consecutive stroke patients in Berlin (Germany) and Ibadan (Nigeria), respectively were evaluated using the measures listed below. The Stroke Levity Scale (SLS) was calculated as maximum power (0-5) in the dexterous hand + maximum power in the weaker lower limb + mobility score-1 (if aphasia present). RESULTS: It took less than 2 min to administer the SLS in contrast to 8 min for the NIHSS. The SLS showed significant correlation to the NIHSS (rho = -0.79, P < 0.0001), the modified Rankin Scale (rho = -0.79, P < 0.0001), and the health-related quality of life (QOL) in stroke patient's questionnaire (rho = 0.78, P < 0.0001). It had Cronbach's alpha of 0.75 (Ibadan) and 0.71 (Berlin). The kappa-value for test-retest reliability was 0.77 with P < 0.0001. CONCLUSIONS: The SLS is a concise, valid, and reliable stroke impairment scale that can be used routinely to monitor outcome in stroke patients. Because it is brief and simple to apply, non-neurologists can be taught to administer it in addition to QOL and disability scales for stroke survivors without significantly increasing the respondent burden.


Asunto(s)
Índice de Severidad de la Enfermedad , Accidente Cerebrovascular/fisiopatología , Anciano , Femenino , Humanos , Masculino , Calidad de Vida , Reproducibilidad de los Resultados
19.
BMC Res Notes ; 9: 356, 2016 Jul 21.
Artículo en Inglés | MEDLINE | ID: mdl-27440117

RESUMEN

BACKGROUND: Evaluation of functional status is difficult in neurological and neurosurgical early rehabilitation patients. The Early Rehabilitation Index (ERI) was introduced in Germany over 20 years ago, but since then validation studies are lacking. The ERI (range -325 to 0 points) includes highly relevant items including the necessity of intermittent mechanical ventilation or tracheostomy. METHODS: The present paper analyzed data from a German multi-center study, enrolling 754 neurological early rehabilitation patients. Together with ERI, Barthel Index (BI), Glasgow Coma Scale (GCS), Glasgow Outcome Score Extended, Coma Remission Scale (CRS), Functional Ambulation Categories and length of stay were obtained. RESULTS: ERI showed significant improvements from admission to discharge (p < 0.001). In addition, there were significant correlations of the ERI upon admission and at discharge with BI, CRS and GCS. CONCLUSIONS: Evaluation of our study data suggest that the ERI may be used as a valid assessment instrument for neurological and neurosurgical early rehabilitation patients.


Asunto(s)
Lesiones Encefálicas/rehabilitación , Escala de Coma de Glasgow/estadística & datos numéricos , Hemorragias Intracraneales/rehabilitación , Traumatismos de los Nervios Periféricos/rehabilitación , Proyectos de Investigación , Actividades Cotidianas , Anciano , Anciano de 80 o más Años , Lesiones Encefálicas/patología , Lesiones Encefálicas/terapia , Femenino , Alemania , Humanos , Hemorragias Intracraneales/patología , Hemorragias Intracraneales/terapia , Tiempo de Internación , Masculino , Persona de Mediana Edad , Traumatismos de los Nervios Periféricos/patología , Traumatismos de los Nervios Periféricos/terapia , Estudios Prospectivos , Investigación en Rehabilitación , Accidente Cerebrovascular/patología , Accidente Cerebrovascular/terapia , Índices de Gravedad del Trauma , Resultado del Tratamiento
20.
Science ; 353(6303)2016 09 02.
Artículo en Inglés | MEDLINE | ID: mdl-27701087

RESUMEN

Volcanic edifices are abundant on rocky bodies of the inner solar system. In the cold outer solar system, volcanism can occur on solid bodies with a water-ice shell, but derived cryovolcanic constructs have proved elusive. We report the discovery, using Dawn Framing Camera images, of a landform on dwarf planet Ceres that we argue represents a viscous cryovolcanic dome. Parent material of the cryomagma is a mixture of secondary minerals, including salts and water ice. Absolute model ages from impact craters reveal that extrusion of the dome has occurred recently. Ceres' evolution must have been able to sustain recent interior activity and associated surface expressions. We propose salts with low eutectic temperatures and thermal conductivities as key drivers for Ceres' long-term internal evolution.

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