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1.
Hong Kong Med J ; 30(4): 310-319, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-39138142

RESUMEN

Overactive bladder (OAB) is a common urological disease with a high prevalence in older adult populations. Antimuscarinic drugs have been the most common treatment for OAB for more than a decade, but their anticholinergic side-effects and potential impact on cognitive function among older patients are usually underestimated. This consensus aimed to provide practical recommendations concerning OAB management, with a particular emphasis on older patients. A joint consensus panel was formed by representatives of the Hong Kong Urological Association and the Hong Kong Geriatrics Society. Literature searches regarding OAB and its management were performed in PubMed and Ovid. Several working meetings were held to present and discuss available evidence, develop consensus statements, and vote for the statements. A modified Delphi method was used in this consensus process. To address questions regarding various aspects of OAB, 29 consensus statements were proposed covering the following areas: diagnosis, initial assessment, non-pharmacological treatments, considerations before administration of pharmacological treatments, various pharmacological treatments, combination therapy, and surgical treatment. Twenty-five consensus statements were accepted.


Asunto(s)
Geriatría , Antagonistas Muscarínicos , Vejiga Urinaria Hiperactiva , Humanos , Vejiga Urinaria Hiperactiva/terapia , Vejiga Urinaria Hiperactiva/tratamiento farmacológico , Vejiga Urinaria Hiperactiva/diagnóstico , Hong Kong , Antagonistas Muscarínicos/uso terapéutico , Anciano , Geriatría/normas , Consenso , Sociedades Médicas , Técnica Delphi , Urología/normas
2.
J Appl Microbiol ; 103(3): 507-15, 2007 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-17714383

RESUMEN

AIMS: Freshwater fish has been found to be the reservoir of Laribacter hongkongensis, a recently discovered bacterium associated with community-acquired gastroenteritis. However, little is known about the ecology of this bacterium in the aquatic environment. We carried out a surveillance study to investigate the presence of L. hongkongensis in water and freshwater fish from 10 drinking water reservoirs in Hong Kong. METHODS AND RESULTS: Using membrane filtration, L. hongkongensis was isolated from the waters of six reservoirs, with numbers ranging from 1 to 12 CFU l(-1). Higher recovery rates were observed in summer and during days of higher water and ambient temperatures. Of 27 freshwater fish collected from the reservoirs, L. hongkongensis was recovered from the intestines of two fish, a Goldfish and a Nile tilapia. Overall, 35 different pulsed-field gel electrophoresis patterns are found among the 59 isolates recovered from water and the two isolates from freshwater fish. CONCLUSIONS: The present report represents the first to demonstrate the presence of L. hongkongensis in natural water environments. SIGNIFICANCE AND IMPACT OF THE STUDY: Although it is unlikely that treated, drinking water is an important source of L. hongkongensis-associated gastroenteritis, one should be aware of the possibility of other contaminated water as a source of human infection.


Asunto(s)
Microbiología Ambiental , Peces/microbiología , Agua Dulce/microbiología , Neisseriaceae/aislamiento & purificación , Animales , Recuento de Colonia Microbiana , Infecciones Comunitarias Adquiridas/microbiología , Reservorios de Enfermedades/microbiología , Electroforesis en Gel de Campo Pulsado/métodos , Microbiología de Alimentos , Gastroenteritis/microbiología , Hong Kong , Humanos , Neisseriaceae/genética , Fenotipo , Filogenia , ARN Bacteriano/genética , ARN Ribosómico 16S/genética , Microbiología del Agua , Abastecimiento de Agua
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