Búsqueda | Portal de Búsqueda de la BVS

1.

TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue.

Zhao, Peng; Wong, Kai In; Sun, Xiaoli; Reilly, Shannon M; Uhm, Maeran; Liao, Zhongji; Skorobogatko, Yuliya; Saltiel, Alan R.

Cell ; 172(4): 731-743.e12, 2018 02 08.

Artículo en Inglés | MEDLINE | ID: mdl-29425491

2.

A futile approach to fighting obesity?

Reilly, Shannon M; Saltiel, Alan R.

Cell ; 163(3): 539-40, 2015 Oct 22.

Artículo en Inglés | MEDLINE | ID: mdl-26496598

3.

Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes.

Keinan, Omer; Valentine, Joseph M; Xiao, Haopeng; Mahata, Sushil K; Reilly, Shannon M; Abu-Odeh, Mohammad; Deluca, Julia H; Dadpey, Benyamin; Cho, Leslie; Pan, Austin; Yu, Ruth T; Dai, Yang; Liddle, Christopher; Downes, Michael; Evans, Ronald M; Lusis, Aldons J; Laakso, Markku; Chouchani, Edward T; Rydén, Mikael; Saltiel, Alan R.

Nature ; 599(7884): 296-301, 2021 11.

Artículo en Inglés | MEDLINE | ID: mdl-34707293

4.

YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity.

Wang, Lirui; Mazagova, Magdalena; Pan, Chuyue; Yang, Song; Brandl, Katharina; Liu, Jun; Reilly, Shannon M; Wang, Yanhan; Miao, Zhaorui; Loomba, Rohit; Lu, Na; Guo, Qinglong; Liu, Jihua; Yu, Ruth T; Downes, Michael; Evans, Ronald M; Brenner, David A; Saltiel, Alan R; Beutler, Bruce; Schnabl, Bernd.

Proc Natl Acad Sci U S A ; 116(30): 15184-15193, 2019 07 23.

Artículo en Inglés | MEDLINE | ID: mdl-31289229

5.

Countering inflammatory signals in obesity.

Reilly, Shannon M; Saltiel, Alan R.

Nat Immunol ; 15(5): 410-1, 2014 May.

Artículo en Inglés | MEDLINE | ID: mdl-24747704

6.

RalA controls glucose homeostasis by regulating glucose uptake in brown fat.

Skorobogatko, Yuliya; Dragan, Morgan; Cordon, Claudia; Reilly, Shannon M; Hung, Chao-Wei; Xia, Wenmin; Zhao, Peng; Wallace, Martina; Lackey, Denise E; Chen, Xiao-Wei; Osborn, Olivia; Bogner-Strauss, Juliane G; Theodorescu, Dan; Metallo, Christian M; Olefsky, Jerrold M; Saltiel, Alan R.

Proc Natl Acad Sci U S A ; 115(30): 7819-7824, 2018 07 24.

Artículo en Inglés | MEDLINE | ID: mdl-29915037

7.

Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKÎµ and Reveal Mechanisms for Selective Inhibition.

Beyett, Tyler S; Gan, Xinmin; Reilly, Shannon M; Chang, Louise; Gomez, Andrew V; Saltiel, Alan R; Showalter, Hollis D; Tesmer, John J G.

Mol Pharmacol ; 94(4): 1210-1219, 2018 10.

Artículo en Inglés | MEDLINE | ID: mdl-30082428

8.

Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKÎµ for the treatment of obesity.

Beyett, Tyler S; Gan, Xinmin; Reilly, Shannon M; Gomez, Andrew V; Chang, Louise; Tesmer, John J G; Saltiel, Alan R; Showalter, Hollis D.

Bioorg Med Chem ; 26(20): 5443-5461, 2018 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-30270002

9.

Adipsin and Adipocyte-derived C3aR1 Regulate Thermogenic Fat in a Sex-dependent Fashion.

Ma, Lunkun; Gilani, Ankit; Rubio-Navarro, Alfonso; Cortada, Eric; Li, Ang; Reilly, Shannon M; Tang, Liling; Lo, James C.

JCI Insight ; 2024 May 07.

Artículo en Inglés | MEDLINE | ID: mdl-38713526

10.

Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation.

Xia, Wenmin; Veeragandham, Preethi; Cao, Yu; Xu, Yayun; Rhyne, Torrey E; Qian, Jiaxin; Hung, Chao-Wei; Zhao, Peng; Jones, Ying; Gao, Hui; Liddle, Christopher; Yu, Ruth T; Downes, Michael; Evans, Ronald M; Rydén, Mikael; Wabitsch, Martin; Wang, Zichen; Hakozaki, Hiroyuki; Schöneberg, Johannes; Reilly, Shannon M; Huang, Jianfeng; Saltiel, Alan R.

Nat Metab ; 6(2): 273-289, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-38286821

11.

Culture and Differentiation of Primary Preadipocytes from Mouse Subcutaneous White Adipose Tissue.

DeLuca, Julia H; Reilly, Shannon M.

Methods Mol Biol ; 2662: 11-24, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37076667

12.

Measuring the Rate of Lipolysis in Ex vivo Murine Adipose Tissue and Primary Preadipocytes Differentiated In Vitro.

Bridge-Comer, Pania E; Reilly, Shannon M.

J Vis Exp ; (193)2023 03 17.

Artículo en Inglés | MEDLINE | ID: mdl-37010285

13.

Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling.

Luan, Danny; Dadpey, Benyamin; Zaid, Jessica; Bridge-Comer, Pania E; DeLuca, Julia H; Xia, Wenmin; Castle, Joshua; Reilly, Shannon M.

Diabetes ; 72(3): 367-374, 2023 03 01.

Artículo en Inglés | MEDLINE | ID: mdl-36449000

14.

Role of peroxisome proliferator-activated receptor {delta}/{beta} in hepatic metabolic regulation.

Liu, Sihao; Hatano, Ben; Zhao, Minghui; Yen, Chen-Chung; Kang, Kihwa; Reilly, Shannon M; Gangl, Matthew R; Gorgun, Cem; Balschi, James A; Ntambi, James M; Lee, Chih-Hao.

J Biol Chem ; 286(2): 1237-47, 2011 Jan 14.

Artículo en Inglés | MEDLINE | ID: mdl-21059653

15.

Xanthine oxidase inhibitor urate-lowering therapy titration to target decreases serum free fatty acids in gout and suppresses lipolysis by adipocytes.

Guma, Monica; Dadpey, Benyamin; Coras, Roxana; Mikuls, Ted R; Hamilton, Bartlett; Quehenberger, Oswald; Thorisdottir, Hilda; Bittleman, David; Lauro, Kimberly; Reilly, Shannon M; Liu-Bryan, Ru; Terkeltaub, Robert.

Arthritis Res Ther ; 24(1): 175, 2022 07 25.

Artículo en Inglés | MEDLINE | ID: mdl-35879786

16.

FGF21 is required for the metabolic benefits of IKKÎµ/TBK1 inhibition.

Reilly, Shannon M; Abu-Odeh, Mohammad; Ameka, Magdalene; DeLuca, Julia H; Naber, Meghan C; Dadpey, Benyamin; Ebadat, Nima; Gomez, Andrew V; Peng, Xiaoling; Poirier, BreAnne; Walk, Elyse; Potthoff, Matthew J; Saltiel, Alan R.

J Clin Invest ; 131(10)2021 05 17.

Artículo en Inglés | MEDLINE | ID: mdl-33822771

17.

Chop/Ddit3 depletion in ß cells alleviates ER stress and corrects hepatic steatosis in mice.

Yong, Jing; Parekh, Vishal S; Reilly, Shannon M; Nayak, Jonamani; Chen, Zhouji; Lebeaupin, Cynthia; Jang, Insook; Zhang, Jiangwei; Prakash, Thazha P; Sun, Hong; Murray, Sue; Guo, Shuling; Ayala, Julio E; Satin, Leslie S; Saltiel, Alan R; Kaufman, Randal J.

Sci Transl Med ; 13(604)2021 07 28.

Artículo en Inglés | MEDLINE | ID: mdl-34321322

18.

FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes.

Abu-Odeh, Mohammad; Zhang, Yuan; Reilly, Shannon M; Ebadat, Nima; Keinan, Omer; Valentine, Joseph M; Hafezi-Bakhtiari, Maziar; Ashayer, Hadeel; Mamoun, Lana; Zhou, Xin; Zhang, Jin; Yu, Ruth T; Dai, Yang; Liddle, Christopher; Downes, Michael; Evans, Ronald M; Kliewer, Steven A; Mangelsdorf, David J; Saltiel, Alan R.

Cell Rep ; 35(13): 109331, 2021 06 29.

Artículo en Inglés | MEDLINE | ID: mdl-34192547

19.

TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation.

Huh, Jin Young; Reilly, Shannon M; Abu-Odeh, Mohammad; Murphy, Anne N; Mahata, Sushil K; Zhang, Jinyu; Cho, Yoori; Seo, Jong Bae; Hung, Chao-Wei; Green, Courtney R; Metallo, Christian M; Saltiel, Alan R.

Cell Metab ; 32(6): 1012-1027.e7, 2020 12 01.

Artículo en Inglés | MEDLINE | ID: mdl-33152322

20.

Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3.

Reilly, Shannon M; Hung, Chao-Wei; Ahmadian, Maryam; Zhao, Peng; Keinan, Omer; Gomez, Andrew V; DeLuca, Julia H; Dadpey, Benyamin; Lu, Donald; Zaid, Jessica; Poirier, BreAnne; Peng, Xiaoling; Yu, Ruth T; Downes, Michael; Liddle, Christopher; Evans, Ronald M; Murphy, Anne N; Saltiel, Alan R.

Nat Metab ; 2(7): 620-634, 2020 07.

Artículo en Inglés | MEDLINE | ID: mdl-32694788

Portal de Búsqueda de la BVS

Información y Conocimiento para la Salud

Configurar filtros

Su selección (0)

Formato de exportación:

Exportar: