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PLoS One ; 14(3): e0212944, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-30830919

RESUMEN

Connections between interindividual differences and people's behavior has been widely researched in various contexts, often by using top-down group comparisons to explain interindividual differences. In contrast, in this study, we apply a bottom-up approach in which we identify meaningful clusters in people's concerns about various areas of life (e.g., their own health, their financial situation, the environment). We apply a novel method, Dirichlet clustering, to large-scale longitudinal data from the German Socioeconomic Panel Study (SOEP) to investigate whether concerns of people living in Germany evaluated in 2010 (t0) cluster participants into robust and separable groups, and whether these groups vary regarding their party identification in 2017 (t0 + 7). Clustering results suggest a range of different groups with specific concern patterns. Some of these notably specific patterns of concerns indicate links to party identification. In particular, some patterns show an increased identification with smaller parties as the 'Bündnis 90/Die Grünen' ('Greens'), the left wing party 'Die Linke' ('The Left') or the right-wing party 'Alternative für Deutschland' ('Alternative for Germany', AfD). Considering that we identify as many as 37 clusters in total, among them at least six with clearly different party identification, it can also be concluded that the complexity of political concerns may be larger than has been assumed before.


Asunto(s)
Análisis por Conglomerados , Modelos Psicológicos , Política , Adulto , Anciano , Femenino , Alemania , Humanos , Estudios Longitudinales , Masculino , Persona de Mediana Edad
3.
Invest Ophthalmol Vis Sci ; 54(8): 5578-83, 2013 Aug 15.
Artículo en Inglés | MEDLINE | ID: mdl-23847319

RESUMEN

PURPOSE: To visualize the precorneal tear film with ultrahigh-resolution spectral domain optical coherence tomography, enabling quantification of tear film thickness in healthy subjects. METHODS: A custom-built spectral domain optical coherence tomography system comprising a broadband titanium:sapphire laser operating at 800 nm and a high-speed charge coupled device (CCD) camera with a read-out rate of 47 kHz was used for measurement of precorneal tear film thickness. The system provides a theoretical axial resolution of 1.2 µm in tissue. The signal-to-noise ratio close to the zero delay was measured with 94 dB. A total of 26 healthy subjects were included in this study. Measurement was started immediately after blinking and averaged over a period of 1 second. In a subset of eight healthy subjects, the reproducibility of the approach was studied by measuring the tear film thickness every 10 minutes over 1 hour. RESULTS: The average central tear film thickness of the measured population was 4.79 ± 0.88 µm. Reproducibility was very high, with an intraclass correlation coefficient of 0.97. A breakup of the tear film was observed in one subject after 14 seconds. CONCLUSIONS: Our data indicate that the human precorneal tear film can be measured with excellent reproducibility using ultrahigh-resolution optical coherence tomography. This technique may be a valuable tool in the management of dry eye syndrome.


Asunto(s)
Córnea/metabolismo , Aumento de la Imagen , Lágrimas/química , Tomografía de Coherencia Óptica/métodos , Adulto , Parpadeo , Córnea/patología , Síndromes de Ojo Seco/diagnóstico , Síndromes de Ojo Seco/metabolismo , Síndromes de Ojo Seco/fisiopatología , Femenino , Humanos , Masculino , Valores de Referencia , Reproducibilidad de los Resultados , Adulto Joven
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