Material properties and bioactivity of a resin infiltrant functionalized with polyhedral oligomeric silsesquioxanes.

OBJECTIVES: To investigate the effect of methacrylate polyhedral oligomeric silsesquioxanes (POSS-8) on various material properties and mineral precipitation potential of a resin infiltrant. METHODS: A TEGDMA-based resin infiltrant was mixed with 0.5, 1, 3, 5 or 10 wt% POSS-8 or left unchanged (control). Degree of conversion (DC), water sorption (WS), viscosity, elastic modulus (E-modulus), flexural strength (FS), Knoop microhardness (KHN) and softening ratio (SR) were assessed. Growth of calcium phosphate (Ca/P) precipitates infiltrant-treated bovine enamel and dentin specimens immersed in artificial saliva or artificial dentinal fluid, respectively, for 28 days was analyzed by scanning electron microscopy and energy-dispersive X-ray spectroscopy. For viscosity assessment, pure TEGDMA filled with 0-10 wt% POSS-8 was used. Statistical analyses were performed using ANOVA and Tukey's post-hoc tests (p < 0.05). RESULTS: POSS-8 did not change the flexural strength, water sorption and softening ratio. The apparent degree of conversion was increased at lower concentrations only while E-modulus remained constant in almost all groups. The particles led to a slight decrease of KHN at concentrations below 3%. The effect on viscosity is comparable to the reinforcement effect. Ca/P precipitates formed on dentin specimens treated with POSS-8-filled infiltrant after 4 weeks of immersion, but were not detected on the control infiltrant. The mineral precipitation on enamel was not improved by POSS-8. SIGNIFICANCE: POSS-8 particles did not worsen the material properties of the resin infiltrant, while the Ca/P precipitation on dentin was stimulated.

Rh immune globulin after genetic amniocentesis: impact on pregnancy outcome.

Although Rh immune globulin is commonly given to Rh-negative women undergoing genetic amniocentesis, there is little documentation of the necessity, efficacy, or safety of this policy. In this study, reproductive outcomes in 147 women each receiving 150 micrograms of Rh immune globulin after genetic amniocentesis were compared with those of an equal number of Rh-positive amniocentesis control women. No significant differences were found in the incidence of midtrimester pregnancy loss, mean gestational age at delivery, mean birth weight, or frequency of preterm deliveries (P greater than 0.05 for all parameters). While two antepartum stillbirths occurred in the study group and none in the control population, causes unrelated to Rh immune globulin administration were apparent for both fetal deaths (one multiple congenital anomaly syndrome, one abruptio placentae at 38 weeks). Of the 103 Rh-negative women giving birth to Rh-positive infants, none were overtly sensitized at the time of delivery. It is concluded that second trimester Rh immune globulin administration does not increase the risk of pregnancy loss.

ECT in the treatment of the catatonic syndrome.

OBJECTIVE: To determine the efficacy of ECT in the treatment of the catatonic syndrome and to identify predictors of good response. METHOD: 28 cases of catatonia in 22 patients admitted to a psychiatry or medical psychiatry inpatient unit between January 1989 and June 1992 were retrospectively evaluated. Cases were included if they met criteria for catatonia as described by Kahlbaum, i.e., 4 or more signs including immobility, mutism, withdrawal, staring, rigidity, posturing/gimacing, negativism, waxy flexibility, echo phenomena, stereotypy, and verbigeration. Primary diagnoses were: Major Depressive Disorder (8), Bipolar Affective Disorder (5), schizophrenia (5), schizoaffective disorder (2) and organic mental disorder (2). Mean age was 54.5 years; sex ratio was 15 females to 7 males. Patients received a mean of 12.0 treatments with mean seizure duration 50.9 s (by EEG) per treatment. RESULTS: By Kahlbaum criteria, resolution of the catatonic syndrome occurred in 26 out of 28 cases (93%). The mean number of signs present per patient prior to ECT was 5.6 versus 0.93 following ECT (p = 0.00001). Overall, ECT brought about resolution of 83.5% of all symptoms with 98% resolution of primary symptoms and 74% resolution of secondary symptoms. CONCLUSIONS: ECT is an effective treatment of the catatonic syndrome. ECT is effective in the resolution of both cardinal (primary) and secondary signs of catatonia. In this study, there is not a statistically significant difference in the effectiveness of the resolution of catatonic symptoms in persons with affective disorder versus schizophrenia.

A small area analysis of psychiatric hospitalizations to general hospitals. Effects of community mental health centers.

Population-based psychiatric admission rates vary across geographic areas, but reasons for this variation are unknown. Insofar as Community Mental Health Centers (CMHCs) provide outpatient services that may deter the need for hospitalization, the presence and structural characteristics of CMHCs may have an impact on a population's psychiatric admission rates. This study uses small area analysis to examine how general hospital psychiatric admission rates are associated with CMHC characteristics. Based on a survey of all CMHCs in Iowa and corresponding small area variation data, it was found that population admission rates were higher in areas closer to the CMHC and lower in outlying catchment areas, adjusting for age, sex, and urban/rural differences in populations. There was little evidence that differences in staffing and service variables influenced admission rates, although greater CMHC staff coverage by social workers and psychiatric residents was associated with lower admission rates. The results suggest that CMHCs do not lower an area's hospitalization rate, and in fact, the presence of CMHCs may promote a "supplier-induced demand" phenomenon of higher admissions.

A survey of utilization of psychiatrists in community mental health centers in Iowa.

Community mental health centers in Iowa were surveyed by mail in 1993 to obtain quantitative data on the utilization of psychiatrists at the centers. Responses from all 37 centers indicated that they employed a total of 34 full-time-equivalent (FTE) psychiatrists, representing about 18 percent of the psychiatrist-hours available in the state. The mean number of psychiatrist-hours per week per center was 36.9. New patients waited a mean of 30 days for an initial assessment by a psychiatrist. Seventy-three percent of the centers indicated they could use additional psychiatrist-hours.

A survey of county boards' views of funding for mental retardation versus funding for mental illness.

The state of Iowa mandates services for persons with mental retardation but not for those with mental illness, resulting in widely divergent spending for the two populations. Members of 98 of the 99 county boards of supervisors were interviewed to determine differences in attitudes about services and funding priorities. Respondents were more willing to provide supportive services to persons with mental retardation and acute treatment to persons with mental illness. Only 16 percent believed that persons with chronic mental illness should be a first priority for mental health funds. Respondents tended to disagree not about whether services should be funded but about who should fund them. Three-fourths believed that the state should fund such services.

County funding of mental health services in a rural state.

Relationships between funding for mental illness in Iowa counties and county wealth, political activism, need for public services, rural culture, and policy makers' attitudes were examined. Counties with fewer people, lower proportions of persons with college education, higher proportions of rural and elderly residents, higher rates of poverty, and a higher proportion of income from farms spent less money on mental health services. Regression analysis indicated that the size of the county population and the proportion of persons receiving Medicaid funds explained 96 percent of the variation between county budgets.

Relationship between service effectiveness and satisfaction among persons receiving Medicaid mental health services.

Relationships between service satisfaction, life satisfaction, and self-reported mental health status were examined for Iowa Medicaid mental health service recipients. Of the 16,579 persons who received services in 1993, a mail-out survey was sent to 2,520 persons and returned by 815 (32.3 percent). Persons with schizophrenia reported greater service satisfaction and life satisfaction than persons with other diagnoses, and their ratings of their mental health were higher. A relationship between service satisfaction and current life satisfaction was observed for persons with schizophrenia, affective disorder and adjustment disorder, but not for persons with anxiety disorder.

Acceptability of telepsychiatry to a rural population.

Sixty-seven residents of a rural Midwestern state were surveyed by telephone to determine which factors influence their willingness to receive mental health services through live, two-way audio and video transmission. Two-thirds of the survey respondents were willing to participate in telepsychiatry. Many expressed reluctance, however. They were concerned about maintaining confidentiality, and they perceived telepsychiatry as impersonal. Medicare enrollees and older survey respondents were less willing than younger respondents to endorse the use of telemedicine.

Implementation of Medicaid Managed Mental Health Care in Iowa: problems and solutions.

Under the terms of a 1915(b) waiver, Iowa implemented a statewide carve-out program in 1995 for the management of mental health services for Medicaid recipients by contracting with a private for-profit corporation. In this commentary, the strategy used to develop the Medicaid managed care contract in Iowa is briefly summarized. Problems that were encountered in program implementation and regulatory attempts to address those issues are described. Suggestions for other states regarding the development, implementation, and oversight of contracts for managed care so that they might be able to deliver comprehensive mental health care services with acceptable standards of care quality are offered. By including appropriate contract specifications, providing mechanisms for oversight, and enforcing standards of care in Medicaid managed care contracts, many problems that occurred in Iowa may have been minimized or avoided. This experience can provide a valuable lesson for similar program initiatives in other states.

Quality assessment in a Medicaid managed mental health care plan: an Iowa case study.

Clinical quality was assessed in a statewide Medicaid managed mental health care program. Because of the limited quantity and scope of the available clinical data, the quality of clinical care could not be adequately assessed. The implications of this finding for the evaluation and oversight of quality in public sector managed care plans is discussed.

A survey of burnout among mental health center directors in a rural state.

The executive directors of all Iowa community mental health centers were surveyed in order to determine the relationship between work environment and job burnout. Organizational characteristics related to "rurality," i.e., location in a rural county, fewer employees, smaller budgets, and more time spent in direct clinical care, were not associated with burnout among directors in this rural state. Implications of the effect of service reorganization on burnout in human service providers in regard to rural health policy, work force issues, and directions for future research are discussed.

Telepsychiatry in the heartland: if we build it, will they come?

The quality of care provided by telemedicine and its acceptability to persons who live in rural areas is largely undetermined. In this study, service satisfaction and functional status in persons using telemedicine was compared to those receiving face-to-face services at two rural sites over a 2-year study period. Similar ratings of satisfaction and clinical status were observed in twelve patients who received services under both modalities. Although there are many obstacles to successful program implementation, telepsychiatry appears to offer an acceptable and adequate alternative mode of service delivery to persons who live in rural areas.

Self-report of improvement following hospitalization for electroconvulsive therapy: relationship to functional status and service use.

From the perspective of the consumer, improvement is important in the assessment of treatment outcome. In order to gain a better understanding of health related factors that are meaningful to service recipients, patients who had been hospitalized for electroconvulsive therapy were surveyed following discharge to the community. Self-reported improvement was related to frequency of social contact and being able to engage in useful work. It was also related to a global-assessment-of-functioning score at the time of discharge from the hospital. The receipt of aftercare was not related to the degree of self-reported improvement in this study.

Clinical significance of persistent amniotic fluid leakage after genetic amniocentesis.

Chronic amniotic fluid leakage is a rare complication of genetic amniocentesis. Pregnancy outcomes in two such patients are presented and six previous cases reviewed. Although chorioamnionitis has not been reported, potentially serious complications may occur including an increased risk for pre-term delivery and fetal skeletal deformity. While conservative management of post-amniocentesis amniotic fluid leakage is advocated, patients should be advised of these risks.