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1.

AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue.

Steculorum, Sophie M; Ruud, Johan; Karakasilioti, Ismene; Backes, Heiko; Engström Ruud, Linda; Timper, Katharina; Hess, Martin E; Tsaousidou, Eva; Mauer, Jan; Vogt, Merly C; Paeger, Lars; Bremser, Stephan; Klein, Andreas C; Morgan, Donald A; Frommolt, Peter; Brinkkötter, Paul T; Hammerschmidt, Philipp; Benzing, Thomas; Rahmouni, Kamal; Wunderlich, F Thomas; Kloppenburg, Peter; Brüning, Jens C.

Cell ; 165(1): 125-138, 2016 Mar 24.

Artículo en Inglés | MEDLINE | ID: mdl-27015310

2.

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin.

Mauer, Jan; Chaurasia, Bhagirath; Goldau, Julia; Vogt, Merly C; Ruud, Johan; Nguyen, Khoa D; Theurich, Sebastian; Hausen, A Christine; Schmitz, Joel; Brönneke, Hella S; Estevez, Emma; Allen, Tamara L; Mesaros, Andrea; Partridge, Linda; Febbraio, Mark A; Chawla, Ajay; Wunderlich, F Thomas; Brüning, Jens C.

Nat Immunol ; 15(5): 423-30, 2014 May.

Artículo en Inglés | MEDLINE | ID: mdl-24681566

3.

Knockout of STE20-type kinase TAOK3 does not attenuate diet-induced NAFLD development in mice.

Xia, Ying; Andersson, Emma; Caputo, Mara; Cansby, Emmelie; Sedda, Francesca; Font-Gironès, Ferran; Ruud, Johan; Kurhe, Yeshwant; Hallberg, Bengt; Marschall, Hanns-Ulrich; Asterholm, Ingrid Wernstedt; Romeo, Stefano; Blüher, Matthias; Mahlapuu, Margit.

Mol Med ; 29(1): 138, 2023 Oct 20.

Artículo en Inglés | MEDLINE | ID: mdl-37864157

4.

Metabolism: Light on leptin link to lipolysis.

Ruud, Johan; Brüning, Jens C.

Nature ; 527(7576): 43-4, 2015 Nov 05.

Artículo en Inglés | MEDLINE | ID: mdl-26536954

5.

Inflammation- and tumor-induced anorexia and weight loss require MyD88 in hematopoietic/myeloid cells but not in brain endothelial or neural cells.

Ruud, Johan; Wilhelms, Daniel Björk; Nilsson, Anna; Eskilsson, Anna; Tang, Yan-Juan; Ströhle, Peter; Caesar, Robert; Schwaninger, Markus; Wunderlich, Thomas; Bäckhed, Fredrik; Engblom, David; Blomqvist, Anders.

FASEB J ; 27(5): 1973-80, 2013 May.

Artículo en Inglés | MEDLINE | ID: mdl-23395911

6.

Activation of GFRAL⁺ neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor.

Engström Ruud, Linda; Font-Gironès, Ferran; Zajdel, Joanna; Kern, Lara; Teixidor-Deulofeu, Júlia; Mannerås-Holm, Louise; Carreras, Alba; Becattini, Barbara; Björefeldt, Andreas; Hanse, Eric; Fenselau, Henning; Solinas, Giovanni; Brüning, Jens C; Wunderlich, Thomas F; Bäckhed, Fredrik; Ruud, Johan.

Cell Rep ; 43(4): 113960, 2024 Apr 23.

Artículo en Inglés | MEDLINE | ID: mdl-38507407

7.

Cancer-induced anorexia in tumor-bearing mice is dependent on cyclooxygenase-1.

Ruud, Johan; Nilsson, Anna; Engström Ruud, Linda; Wang, Wenhua; Nilsberth, Camilla; Iresjö, Britt-Marie; Lundholm, Kent; Engblom, David; Blomqvist, Anders.

Brain Behav Immun ; 29: 124-135, 2013 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-23305935

8.

Interleukin-6 primarily produced by non-hematopoietic cells mediates the lipopolysaccharide-induced febrile response.

Hamzic, Namik; Tang, Yanjuan; Eskilsson, Anna; Kugelberg, Unn; Ruud, Johan; Jönsson, Jan-Ingvar; Blomqvist, Anders; Nilsberth, Camilla.

Brain Behav Immun ; 33: 123-30, 2013 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-23827828

9.

Reduction of body weight by increased loading is associated with activation of norepinephrine neurones in the medial nucleus of the solitary tract.

Zlatkovic, Jovana; Dalmau Gasull, Adrià; Hägg, Daniel; Font-Gironès, Ferran; Bellman, Jakob; Meister, Björn; Palsdottir, Vilborg; Ruud, Johan; Ohlsson, Claes; Dickson, Suzanne L; Anesten, Fredrik; Jansson, John-Olov.

J Neuroendocrinol ; 35(12): e13352, 2023 12.

Artículo en Inglés | MEDLINE | ID: mdl-37885347

10.

Inducible prostaglandin E2 synthesis interacts in a temporally supplementary sequence with constitutive prostaglandin-synthesizing enzymes in creating the hypothalamic-pituitary-adrenal axis response to immune challenge.

Elander, Louise; Engström, Linda; Ruud, Johan; Mackerlova, Ludmila; Jakobsson, Per-Johan; Engblom, David; Nilsberth, Camilla; Blomqvist, Anders.

J Neurosci ; 29(5): 1404-13, 2009 Feb 04.

Artículo en Inglés | MEDLINE | ID: mdl-19193887

11.

Deletion of the gene encoding MyD88 protects from anorexia in a mouse tumor model.

Ruud, Johan; Bäckhed, Fredrik; Engblom, David; Blomqvist, Anders.

Brain Behav Immun ; 24(4): 554-7, 2010 May.

Artículo en Inglés | MEDLINE | ID: mdl-20093176

12.

The Fat Mass and Obesity-Associated Protein (FTO) Regulates Locomotor Responses to Novelty via D2R Medium Spiny Neurons.

Ruud, Johan; Alber, Jens; Tokarska, Anna; Engström Ruud, Linda; Nolte, Hendrik; Biglari, Nasim; Lippert, Rachel; Lautenschlager, Änne; Cieslak, Przemyslaw E; Szumiec, Lukasz; Hess, Martin E; Brönneke, Hella S; Krüger, Marcus; Nissbrandt, Hans; Korotkova, Tatiana; Silberberg, Gilad; Rodriguez Parkitna, Jan; Brüning, Jens C.

Cell Rep ; 27(11): 3182-3198.e9, 2019 06 11.

Artículo en Inglés | MEDLINE | ID: mdl-31189104

13.

Identification of rat brainstem neuronal structures activated during cancer-induced anorexia.

Ruud, Johan; Blomqvist, Anders.

J Comp Neurol ; 504(3): 275-86, 2007 Sep 20.

Artículo en Inglés | MEDLINE | ID: mdl-17640050

14.

Anorexia-cachexia syndrome in hepatoma tumour-bearing rats requires the area postrema but not vagal afferents and is paralleled by increased MIC-1/GDF15.

Borner, Tito; Arnold, Myrtha; Ruud, Johan; Breit, Samuel N; Langhans, Wolfgang; Lutz, Thomas A; Blomqvist, Anders; Riediger, Thomas.

J Cachexia Sarcopenia Muscle ; 8(3): 417-427, 2017 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-28025863

15.

Neuroendocrinology: Electromagnetogenetic Control over Feeding and Glucose Metabolism.

Ruud, Johan; Brüning, Jens C.

Curr Biol ; 26(11): R470-3, 2016 06 06.

Artículo en Inglés | MEDLINE | ID: mdl-27269725

16.

Insulin-Dependent Activation of MCH Neurons Impairs Locomotor Activity and Insulin Sensitivity in Obesity.

Hausen, A Christine; Ruud, Johan; Jiang, Hong; Hess, Simon; Varbanov, Hristo; Kloppenburg, Peter; Brüning, Jens C.

Cell Rep ; 17(10): 2512-2521, 2016 12 06.

Artículo en Inglés | MEDLINE | ID: mdl-27926856

17.

Neuronal control of peripheral insulin sensitivity and glucose metabolism.

Ruud, Johan; Steculorum, Sophie M; Brüning, Jens C.

Nat Commun ; 8: 15259, 2017 05 04.

Artículo en Inglés | MEDLINE | ID: mdl-28469281

18.

Lipopolysaccharide-induced fever depends on prostaglandin E2 production specifically in brain endothelial cells.

Engström, Linda; Ruud, Johan; Eskilsson, Anna; Larsson, Anders; Mackerlova, Ludmila; Kugelberg, Unn; Qian, Hong; Vasilache, Ana Maria; Larsson, Peter; Engblom, David; Sigvardsson, Mikael; Jönsson, Jan-Ingvar; Blomqvist, Anders.

Endocrinology ; 153(10): 4849-61, 2012 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-22872578

19.

Cyclooxygenase-1 mediates the immediate corticosterone response to peripheral immune challenge induced by lipopolysaccharide.

Elander, Louise; Ruud, Johan; Korotkova, Marina; Jakobsson, Per-Johan; Blomqvist, Anders.

Neurosci Lett ; 470(1): 10-2, 2010 Feb 05.

Artículo en Inglés | MEDLINE | ID: mdl-20034541

20.

Long-term treatment with antidepressants, but not environmental stimulation, induces expression of NP2 mRNA in hippocampus and medial habenula.

Bjartmar, Lisa; Alkhori, Liza; Ruud, Johan; Mohammed, Abdul H; Marcusson, Jan; Hallbeck, Martin.

Brain Res ; 1328: 25-33, 2010 Apr 30.

Artículo en Inglés | MEDLINE | ID: mdl-20223226

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