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1.
BMC Bioinformatics ; 24(1): 372, 2023 Oct 02.
Artículo en Inglés | MEDLINE | ID: mdl-37784049

RESUMEN

The rising risk of diabetes, particularly in emerging countries, highlights the importance of early detection. Manual prediction can be a challenging task, leading to the need for automatic approaches. The major challenge with biomedical datasets is data scarcity. Biomedical data is often difficult to obtain in large quantities, which can limit the ability to train deep learning models effectively. Biomedical data can be noisy and inconsistent, which can make it difficult to train accurate models. To overcome the above-mentioned challenges, this work presents a new framework for data modeling that is based on correlation measures between features and can be used to process data effectively for predicting diabetes. The standard, publicly available Pima Indians Medical Diabetes (PIMA) dataset is utilized to verify the effectiveness of the proposed techniques. Experiments using the PIMA dataset showed that the proposed data modeling method improved the accuracy of machine learning models by an average of 9%, with deep convolutional neural network models achieving an accuracy of 96.13%. Overall, this study demonstrates the effectiveness of the proposed strategy in the early and reliable prediction of diabetes.


Asunto(s)
Aprendizaje Profundo , Diabetes Mellitus , Humanos , Yoduro de Potasio , Redes Neurales de la Computación , Aprendizaje Automático , Diabetes Mellitus/diagnóstico
2.
Sensors (Basel) ; 22(15)2022 Jul 24.
Artículo en Inglés | MEDLINE | ID: mdl-35898023

RESUMEN

Acute lymphoblastic leukemia (ALL) is a deadly cancer characterized by aberrant accumulation of immature lymphocytes in the blood or bone marrow. Effective treatment of ALL is strongly associated with the early diagnosis of the disease. Current practice for initial ALL diagnosis is performed through manual evaluation of stained blood smear microscopy images, which is a time-consuming and error-prone process. Deep learning-based human-centric biomedical diagnosis has recently emerged as a powerful tool for assisting physicians in making medical decisions. Therefore, numerous computer-aided diagnostic systems have been developed to autonomously identify ALL in blood images. In this study, a new Bayesian-based optimized convolutional neural network (CNN) is introduced for the detection of ALL in microscopic smear images. To promote classification performance, the architecture of the proposed CNN and its hyperparameters are customized to input data through the Bayesian optimization approach. The Bayesian optimization technique adopts an informed iterative procedure to search the hyperparameter space for the optimal set of network hyperparameters that minimizes an objective error function. The proposed CNN is trained and validated using a hybrid dataset which is formed by integrating two public ALL datasets. Data augmentation has been adopted to further supplement the hybrid image set to boost classification performance. The Bayesian search-derived optimal CNN model recorded an improved performance of image-based ALL classification on test set. The findings of this study reveal the superiority of the proposed Bayesian-optimized CNN over other optimized deep learning ALL classification models.


Asunto(s)
Redes Neurales de la Computación , Leucemia-Linfoma Linfoblástico de Células Precursoras , Teorema de Bayes , Humanos , Microscopía , Leucemia-Linfoma Linfoblástico de Células Precursoras/diagnóstico
3.
Sensors (Basel) ; 22(13)2022 Jun 30.
Artículo en Inglés | MEDLINE | ID: mdl-35808433

RESUMEN

One of the most promising research areas in the healthcare industry and the scientific community is focusing on the AI-based applications for real medical challenges such as the building of computer-aided diagnosis (CAD) systems for breast cancer. Transfer learning is one of the recent emerging AI-based techniques that allow rapid learning progress and improve medical imaging diagnosis performance. Although deep learning classification for breast cancer has been widely covered, certain obstacles still remain to investigate the independency among the extracted high-level deep features. This work tackles two challenges that still exist when designing effective CAD systems for breast lesion classification from mammograms. The first challenge is to enrich the input information of the deep learning models by generating pseudo-colored images instead of only using the input original grayscale images. To achieve this goal two different image preprocessing techniques are parallel used: contrast-limited adaptive histogram equalization (CLAHE) and Pixel-wise intensity adjustment. The original image is preserved in the first channel, while the other two channels receive the processed images, respectively. The generated three-channel pseudo-colored images are fed directly into the input layer of the backbone CNNs to generate more powerful high-level deep features. The second challenge is to overcome the multicollinearity problem that occurs among the high correlated deep features generated from deep learning models. A new hybrid processing technique based on Logistic Regression (LR) as well as Principal Components Analysis (PCA) is presented and called LR-PCA. Such a process helps to select the significant principal components (PCs) to further use them for the classification purpose. The proposed CAD system has been examined using two different public benchmark datasets which are INbreast and mini-MAIS. The proposed CAD system could achieve the highest performance accuracies of 98.60% and 98.80% using INbreast and mini-MAIS datasets, respectively. Such a CAD system seems to be useful and reliable for breast cancer diagnosis.


Asunto(s)
Neoplasias de la Mama , Redes Neurales de la Computación , Neoplasias de la Mama/diagnóstico por imagen , Femenino , Humanos , Modelos Logísticos , Aprendizaje Automático , Mamografía/métodos
4.
Sci Rep ; 14(1): 16879, 2024 07 23.
Artículo en Inglés | MEDLINE | ID: mdl-39043755

RESUMEN

This research endeavors to prognosticate gender by harnessing the potential of skull computed tomography (CT) images, given the seminal role of gender identification in the realm of identification. The study encompasses a corpus of CT images of cranial structures derived from 218 male and 203 female subjects, constituting a total cohort of 421 individuals within the age bracket of 25 to 65 years. Employing deep learning, a prominent subset of machine learning algorithms, the study deploys convolutional neural network (CNN) models to excavate profound attributes inherent in the skull CT images. In pursuit of the research objective, the focal methodology involves the exclusive application of deep learning algorithms to image datasets, culminating in an accuracy rate of 96.4%. The gender estimation process exhibits a precision of 96.1% for male individuals and 96.8% for female individuals. The precision performance varies across different selections of feature numbers, namely 100, 300, and 500, alongside 1000 features without feature selection. The respective precision rates for these selections are recorded as 95.0%, 95.5%, 96.2%, and 96.4%. It is notable that gender estimation via visual radiography mitigates the discrepancy in measurements between experts, concurrently yielding an expedited estimation rate. Predicated on the empirical findings of this investigation, it is inferred that the efficacy of the CNN model, the configurational intricacies of the classifier, and the judicious selection of features collectively constitute pivotal determinants in shaping the performance attributes of the proposed methodology.


Asunto(s)
Antropología Forense , Caracteres Sexuales , Cráneo , Tomografía Computarizada por Rayos X , Cráneo/diagnóstico por imagen , Tomografía Computarizada por Rayos X/normas , Antropología Forense/métodos , Aprendizaje Profundo , Humanos , Masculino , Femenino , Reproducibilidad de los Resultados , Adulto , Persona de Mediana Edad , Anciano , Redes Neurales de la Computación
5.
Comput Biol Med ; 180: 108984, 2024 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-39128177

RESUMEN

The identification of tumors through gene analysis in microarray data is a pivotal area of research in artificial intelligence and bioinformatics. This task is challenging due to the large number of genes relative to the limited number of observations, making feature selection a critical step. This paper introduces a novel wrapper feature selection method that leverages a hybrid optimization algorithm combining a genetic operator with a Sinh Cosh Optimizer (SCHO), termed SCHO-GO. The SCHO-GO algorithm is designed to avoid local optima, streamline the search process, and select the most relevant features without compromising classifier performance. Traditional methods often falter with extensive search spaces, necessitating hybrid approaches. Our method aims to reduce the dimensionality and improve the classification accuracy, which is essential in pattern recognition and data analysis. The SCHO-GO algorithm, integrated with a support vector machine (SVM) classifier, significantly enhances cancer classification accuracy. We evaluated the performance of SCHO-GO using the CEC'2022 benchmark function and compared it with seven well-known metaheuristic algorithms. Statistical analyses indicate that SCHO-GO consistently outperforms these algorithms. Experimental tests on eight microarray gene expression datasets, particularly the Gene Expression Cancer RNA-Seq dataset, demonstrate an impressive accuracy of 99.01% with the SCHO-GO-SVM model, highlighting its robustness and precision in handling complex datasets. Furthermore, the SCHO-GO algorithm excels in feature selection and solving mathematical benchmark problems, presenting a promising approach for tumor identification and classification in microarray data analysis.


Asunto(s)
Neoplasias , Máquina de Vectores de Soporte , Humanos , Neoplasias/genética , Algoritmos , Biología Computacional/métodos , Perfilación de la Expresión Génica/métodos
6.
PLoS One ; 19(8): e0309459, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39196913

RESUMEN

The reliable operation of electrical power transmission systems is crucial for ensuring consumer's stable and uninterrupted electricity supply. Faults in electrical power transmission systems can lead to significant disruptions, economic losses, and potential safety hazards. A protective approach is essential for transmission lines to guard against faults caused by natural disturbances, short circuits, and open circuit issues. This study employs an advanced artificial neural network methodology for fault detection and classification, specifically distinguishing between single-phase fault and fault between all three phases and three-phase symmetrical fault. For fault data creation and analysis, we utilized a collection of line currents and voltages for different fault conditions, modelled in the MATLAB environment. Different fault scenarios with varied parameters are simulated to assess the applied method's detection ability. We analyzed the signal data time series analysis based on phase line current and phase line voltage. We employed SMOTE-based data oversampling to balance the dataset. Subsequently, we developed four advanced machine-learning models and one deep-learning model using signal data from line currents and voltage faults. We have proposed an optimized novel glassbox Explainable Boosting (EB) approach for fault detection. The proposed EB method incorporates the strengths of boosting and interpretable tree models. Simulation results affirm the high-efficiency scores of 99% in detecting and categorizing faults on transmission lines compared to traditional fault detection state-of-the-art methods. We conducted hyperparameter optimization and k-fold validations to enhance fault detection performance and validate our approach. We evaluated the computational complexity of fault detection models and augmented it with eXplainable Artificial Intelligence (XAI) analysis to illuminate the decision-making process of the proposed model for fault detection. Our proposed research presents a scalable and adaptable method for advancing smart grid technology, paving the way for more secure and efficient electrical power transmission systems.


Asunto(s)
Suministros de Energía Eléctrica , Redes Neurales de la Computación , Aprendizaje Automático , Electricidad , Algoritmos , Falla de Equipo
7.
Heliyon ; 10(7): e28967, 2024 Apr 15.
Artículo en Inglés | MEDLINE | ID: mdl-38601589

RESUMEN

Plant diseases annually cause damage and loss of much of the crop, if not its complete destruction, and this constitutes a significant challenge for farm owners, governments, and consumers alike. Therefore, identifying and classifying diseases at an early stage is very important in order to sustain local and global food security. In this research, we designed a new method to identify plant diseases by combining transfer learning and Gravitational Search Algorithm (GSA). Two state-of-the-art pretrained models have been adopted for extracting features in this study, which are MobileNetV2 and ResNe50V2. Multilayer feature extraction is applied in this study to ensure representations of plant leaves from different levels of abstraction for precise classification. These features are then concatenated and passed to GSA for optimizing them. Finally, optimized features are passed to Multinomial Logistic Regression (MLR) for final classification. This integration is essential for categorizing 18 different types of infected and healthy leaf samples. The performance of our approach is strengthened by a comparative analysis that incorporates features optimized by the Genetic Algorithm (GA). Additionally, the MLR algorithm is contrasted with K-Nearest Neighbors (KNN). The empirical findings indicate that our model, which has been refined using GSA, achieves very high levels of precision. Specifically, the average precision for MLR is 99.2%, while for KNN it is 98.6%. The resulting results significantly exceed those achieved with GA-optimized features, thereby highlighting the superiority of our suggested strategy. One important result of our study is that we were able to decrease the number of features by more than 50%. This reduction greatly reduces the processing requirements without sacrificing the quality of the diagnosis. This work presents a robust and efficient approach to the early detection of plant diseases. The work demonstrates the utilization of sophisticated computational methods in agriculture, enabling the development of novel data-driven strategies for plant health management, therefore enhancing worldwide food security.

8.
Front Med (Lausanne) ; 11: 1310137, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38357646

RESUMEN

Quality of life is greatly affected by chronic wounds. It requires more intensive care than acute wounds. Schedule follow-up appointments with their doctor to track healing. Good wound treatment promotes healing and fewer problems. Wound care requires precise and reliable wound measurement to optimize patient treatment and outcomes according to evidence-based best practices. Images are used to objectively assess wound state by quantifying key healing parameters. Nevertheless, the robust segmentation of wound images is complex because of the high diversity of wound types and imaging conditions. This study proposes and evaluates a novel hybrid model developed for wound segmentation in medical images. The model combines advanced deep learning techniques with traditional image processing methods to improve the accuracy and reliability of wound segmentation. The main objective is to overcome the limitations of existing segmentation methods (UNet) by leveraging the combined advantages of both paradigms. In our investigation, we introduced a hybrid model architecture, wherein a ResNet34 is utilized as the encoder, and a UNet is employed as the decoder. The combination of ResNet34's deep representation learning and UNet's efficient feature extraction yields notable benefits. The architectural design successfully integrated high-level and low-level features, enabling the generation of segmentation maps with high precision and accuracy. Following the implementation of our model to the actual data, we were able to determine the following values for the Intersection over Union (IOU), Dice score, and accuracy: 0.973, 0.986, and 0.9736, respectively. According to the achieved results, the proposed method is more precise and accurate than the current state-of-the-art.

9.
Comput Biol Med ; 182: 109175, 2024 Sep 24.
Artículo en Inglés | MEDLINE | ID: mdl-39321584

RESUMEN

Bladder cancer (BC) diagnosis presents a critical challenge in biomedical research, necessitating accurate tumor classification from diverse datasets for effective treatment planning. This paper introduces a novel wrapper feature selection (FS) method that leverages a hybrid optimization algorithm combining Orthogonal Learning (OL) with a rime optimization algorithm (RIME), termed mRIME. The mRIME algorithm is designed to avoid local optima, streamline the search process, and select the most relevant features without compromising classifier performance. It also introduces mRIME-SVM, a novel hybrid model integrating modified mRIME for FS with Support Vector Machine (SVM) for classification. The mRIME algorithm is employed as an FS method and is also utilized to fine-tune the hyperparameters of it the It SVM, enhancing the overall classification accuracy. Specifically, mRIME navigates complex search spaces to optimize FS without compromising classifier performance. Evaluated on eight diverse BC datasets, mRIME-SVM outperforms popular metaheuristic algorithms, ensuring precise and reliable diagnostic outcomes. Moreover, the proposed mRIME was employed for tackling global optimization problems. It has been thoroughly assessed using the IEEE Congress on Evolutionary Computation 2022 (CEC'2022) test suite. Comparative analyzes with Gray wolf optimization (GWO), Whale optimization algorithm (WOA), Harris hawks optimization (HHO), Golden Jackal Optimization (GJO), Hunger Game optimization algorithm (HGS), Sinh Cosh Optimizer (SCHO), and the original RIME highlight mRIME's competitiveness and efficacy across diverse optimization tasks. Leveraging mRIME's success, mRIME-SVM achieves high classification accuracy on nine BC datasets, surpassing existing models. Results underscore mRIME's competitiveness and applicability across diverse optimization tasks, extending its utility to enhance BC classification. This study contributes to advancing BC diagnostics with a robust computational framework, promising broader applications in bioinformatics and AI-driven medical research.

10.
Sci Rep ; 14(1): 16593, 2024 07 18.
Artículo en Inglés | MEDLINE | ID: mdl-39025965

RESUMEN

The aim of this study was to test the morphometric features affecting 20-m sprint performance in children at the first level of primary education using machine learning (ML) algorithms. In this study, 130 male and 152 female volunteers aged between 6 and 11 years were included. After obtaining demographic information of the participants, skinfold thickness, diameter and circumference measurements, and 20-m sprint performance were determined. The study conducted three distinct experiments to determine the optimal ML technique for predicting outcomes. Initially, the entire feature space was utilized for training the ML models to establish a baseline performance. In the second experiment, only significant features identified through correlation analysis were used for training and testing the models, enhancing the focus on relevant predictors. Lastly, Principal Component Analysis (PCA) was employed to reduce the feature space, aiming to streamline model complexity while retaining data variance. These experiments collectively aimed to evaluate different feature selection and dimensionality reduction techniques, providing insights into the most effective strategies for optimizing predictive performance in the given context. The correlation-based selected features (Age, Height, waist circumference, hip circumference, leg length, thigh length, foot length) has produced a minimum Mean Squared Error (MSE) value of 0.012 for predicting the sprint performance in children. The effective utilization of correlation analysis in the selection of relevant features for our regression model suggests that the features selected exhibit robust linear associations with the target variable and can be relied upon as predictors.


Asunto(s)
Rendimiento Atlético , Aprendizaje Automático , Carrera , Humanos , Masculino , Femenino , Niño , Carrera/fisiología , Rendimiento Atlético/fisiología , Análisis de Componente Principal , Algoritmos
11.
Comput Biol Med ; 181: 109080, 2024 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-39213707

RESUMEN

Bladder Cancer (BC) is a common disease that comes with a high risk of morbidity, death, and expense. Primary risk factors for BC include exposure to carcinogens in the workplace or the environment, particularly tobacco. There are several difficulties, such as the requirement for a qualified expert in BC classification. The Parrot Optimizer (PO), is an optimization method inspired by key behaviors observed in trained Pyrrhura Molinae parrots, but the PO algorithm becomes stuck in sub-regions, has less accuracy, and a high error rate. So, an Improved variant of the PO (IPO) algorithm was developed using a combination of two strategies: (1) Mirror Reflection Learning (MRL) and (2) Bernoulli Maps (BMs). Both strategies improve optimization performance by avoiding local optimums and striking a compromise between convergence speed and solution diversity. The performance of the proposed IPO is evaluated against eight other competitor algorithms in terms of statistical convergence and other metrics according to Friedman's test and Bonferroni-Dunn test on the IEEE Congress on Evolutionary Computation conducted in 2022 (CEC 2022) test suite functions and nine BC datasets from official repositories. The IPO algorithm ranked number one in best fitness and is more optimal than the other eight MH algorithms for CEC 2022 functions. The proposed IPO algorithm was integrated with the Support Vector Machine (SVM) classifier termed (IPO-SVM) approach for bladder cancer classification purposes. Nine BC datasets were then used to confirm the effectiveness of the proposed IPO algorithm. The experiments show that the IPO-SVM approach outperforms eight recently proposed MH algorithms. Using the nine BC datasets, IPO-SVM achieved an Accuracy (ACC) of 84.11%, Sensitivity (SE) of 98.10%, Precision (PPV) of 95.59%, Specificity (SP) of 95.98%, and F-score (F1) of 94.15%. This demonstrates how the proposed IPO approach can help to classify BCs effectively. The open-source codes are available at https://www.mathworks.com/matlabcentral/fileexchange/169846-an-efficient-improved-parrot-optimizer.


Asunto(s)
Algoritmos , Neoplasias de la Vejiga Urinaria , Neoplasias de la Vejiga Urinaria/clasificación , Humanos
12.
Math Biosci Eng ; 21(4): 5712-5734, 2024 Apr 24.
Artículo en Inglés | MEDLINE | ID: mdl-38872555

RESUMEN

This research introduces a novel dual-pathway convolutional neural network (DP-CNN) architecture tailored for robust performance in Log-Mel spectrogram image analysis derived from raw multichannel electromyography signals. The primary objective is to assess the effectiveness of the proposed DP-CNN architecture across three datasets (NinaPro DB1, DB2, and DB3), encompassing both able-bodied and amputee subjects. Performance metrics, including accuracy, precision, recall, and F1-score, are employed for comprehensive evaluation. The DP-CNN demonstrates notable mean accuracies of 94.93 ± 1.71% and 94.00 ± 3.65% on NinaPro DB1 and DB2 for healthy subjects, respectively. Additionally, it achieves a robust mean classification accuracy of 85.36 ± 0.82% on amputee subjects in DB3, affirming its efficacy. Comparative analysis with previous methodologies on the same datasets reveals substantial improvements of 28.33%, 26.92%, and 39.09% over the baseline for DB1, DB2, and DB3, respectively. The DP-CNN's superior performance extends to comparisons with transfer learning models for image classification, reaffirming its efficacy. Across diverse datasets involving both able-bodied and amputee subjects, the DP-CNN exhibits enhanced capabilities, holding promise for advancing myoelectric control.


Asunto(s)
Algoritmos , Amputados , Electromiografía , Gestos , Redes Neurales de la Computación , Procesamiento de Señales Asistido por Computador , Extremidad Superior , Humanos , Electromiografía/métodos , Extremidad Superior/fisiología , Masculino , Adulto , Femenino , Adulto Joven , Persona de Mediana Edad , Reproducibilidad de los Resultados
13.
Comput Biol Med ; 164: 107237, 2023 09.
Artículo en Inglés | MEDLINE | ID: mdl-37467535

RESUMEN

Medical datasets are primarily made up of numerous pointless and redundant elements in a collection of patient records. None of these characteristics are necessary for a medical decision-making process. Conversely, a large amount of data leads to increased dimensionality and decreased classifier performance in terms of machine learning. Numerous approaches have recently been put out to address this issue, and the results indicate that feature selection can be a successful remedy. To meet the various needs of input patterns, medical diagnostic tasks typically involve learning a suitable categorization model. The k-Nearest Neighbors algorithm (kNN) classifier's classification performance is typically decreased by the input variables' abundance of irrelevant features. To simplify the kNN classifier, essential attributes of the input variables have been searched using the feature selection approach. This paper presents the Coati Optimization Algorithm (DCOA) in a dynamic form as a feature selection technique where each iteration of the optimization process involves the introduction of a different feature. We enhance the exploration and exploitation capability of DCOA by employing dynamic opposing candidate solutions. The most impressive feature of DCOA is that it does not require any preparatory parameter fine-tuning to the most popular metaheuristic algorithms. The CEC'22 test suite and nine medical datasets with various dimension sizes were used to evaluate the performance of the original COA and the proposed dynamic version. The statistical results were validated using the Bonferroni-Dunn test and Kendall's W test and showed the superiority of DCOA over seven well-known metaheuristic algorithms with an overall accuracy of 89.7%, a feature selection of 24%, a sensitivity of 93.35% a specificity of 96.81%, and a precision of 93.90%.


Asunto(s)
Procyonidae , Humanos , Animales , Algoritmos , Aprendizaje Automático
14.
Diagnostics (Basel) ; 13(9)2023 May 03.
Artículo en Inglés | MEDLINE | ID: mdl-37175012

RESUMEN

It is crucial to accurately categorize cancers using microarray data. Researchers have employed a variety of computational intelligence approaches to analyze gene expression data. It is believed that the most difficult part of the problem of cancer diagnosis is determining which genes are informative. Therefore, selecting genes to study as a starting point for cancer classification is common practice. We offer a novel approach that combines the Runge Kutta optimizer (RUN) with a support vector machine (SVM) as the classifier to select the significant genes in the detection of cancer tissues. As a means of dealing with the high dimensionality that characterizes microarray datasets, the preprocessing stage of the ReliefF method is implemented. The proposed RUN-SVM approach is tested on binary-class microarray datasets (Breast2 and Prostate) and multi-class microarray datasets in order to assess its efficacy (i.e., Brain Tumor1, Brain Tumor2, Breast3, and Lung Cancer). Based on the experimental results obtained from analyzing six different cancer gene expression datasets, the proposed RUN-SVM approach was found to statistically beat the other competing algorithms due to its innovative search technique.

15.
Comput Biol Med ; 160: 106966, 2023 06.
Artículo en Inglés | MEDLINE | ID: mdl-37141655

RESUMEN

One of the worst diseases is a brain tumor, which is defined by abnormal development of synapses in the brain. Early detection of brain tumors is essential for improving prognosis, and classifying tumors is a vital step in the disease's treatment. Different classification strategies using deep learning have been presented for the diagnosis of brain tumors. However, several challenges exist, such as the need for a competent specialist in classifying brain cancers by deep learning models and the problem of building the most precise deep learning model for categorizing brain tumors. We propose an evolved and highly efficient model based on deep learning and improved metaheuristic algorithms to address these challenges. Specifically, we develop an optimized residual learning architecture for classifying multiple brain tumors and propose an improved variant of the Hunger Games Search algorithm (I-HGS) based on combining two enhancing strategies: Local Escaping Operator (LEO) and Brownian motion. These two strategies balance solution diversity and convergence speed, boosting the optimization performance and staying away from the local optima. First, we have evaluated the I-HGS algorithm on the IEEE Congress on Evolutionary Computation held in 2020 (CEC'2020) test functions, demonstrating that I-HGS outperformed the basic HGS and other popular algorithms regarding statistical convergence, and various measures. The suggested model is then applied to the optimization of the hyperparameters of the Residual Network 50 (ResNet50) model (I-HGS-ResNet50) for brain cancer identification, proving its overall efficacy. We utilize several publicly available, gold-standard datasets of brain MRI images. The proposed I-HGS-ResNet50 model is compared with other existing studies as well as with other deep learning architectures, including Visual Geometry Group 16-layer (VGG16), MobileNet, and Densely Connected Convolutional Network 201 (DenseNet201). The experiments demonstrated that the proposed I-HGS-ResNet50 model surpasses the previous studies and other well-known deep learning models. I-HGS-ResNet50 acquired an accuracy of 99.89%, 99.72%, and 99.88% for the three datasets. These results efficiently prove the potential of the proposed I-HGS-ResNet50 model for accurate brain tumor classification.


Asunto(s)
Neoplasias Encefálicas , Aprendizaje Profundo , Humanos , Algoritmos , Encéfalo/diagnóstico por imagen , Neoplasias Encefálicas/diagnóstico por imagen
16.
Comput Biol Med ; 165: 107389, 2023 10.
Artículo en Inglés | MEDLINE | ID: mdl-37678138

RESUMEN

This paper introduces a new bio-inspired optimization algorithm named the Liver Cancer Algorithm (LCA), which mimics the liver tumor growth and takeover process. It uses an evolutionary search approach that simulates the behavior of liver tumors when taking over the liver organ. The tumor's ability to replicate and spread to other organs inspires the algorithm. LCA algorithm is developed using genetic operators and a Random Opposition-Based Learning (ROBL) strategy to efficiently balance local and global searches and explore the search space. The algorithm's efficiency is tested on the IEEE Congress of Evolutionary Computation in 2020 (CEC'2020) benchmark functions and compared to seven widely used metaheuristic algorithms, including Genetic Algorithm (GA), particle swarm optimization (PSO), Differential Evolution (DE), Adaptive Guided Differential Evolution Algorithm (AGDE), Improved Multi-Operator Differential Evolution (IMODE), Harris Hawks Optimization (HHO), Runge-Kutta Optimization Algorithm (RUN), weIghted meaN oF vectOrs (INFO), and Coronavirus Herd Immunity Optimizer (CHIO). The statistical results of the convergence curve, boxplot, parameter space, and qualitative metrics show that the LCA algorithm performs competitively compared to well-known algorithms. Moreover, the versatility of the LCA algorithm extends beyond mathematical benchmark problems. It was also successfully applied to tackle the feature selection problem and optimize the support vector machine for various biomedical data classifications, resulting in the creation of the LCA-SVM model. The LCA-SVM model was evaluated in a total of twelve datasets, among which the MonoAmine Oxidase (MAO) dataset stood out, showing the highest performance compared to the other datasets. In particular, the LCA-SVM model achieved an impressive accuracy of 98.704% on the MAO dataset. This outstanding result demonstrates the efficacy and potential of the LCA-SVM approach in handling complex datasets and producing highly accurate predictions. The experimental results indicate that the LCA algorithm surpasses other methods to solve mathematical benchmark problems and feature selection.


Asunto(s)
Neoplasias Hepáticas , Humanos , Algoritmos , Benchmarking , Monoaminooxidasa
17.
Artículo en Inglés | MEDLINE | ID: mdl-38055360

RESUMEN

The Internet of Things (IoT) is capable of controlling the healthcare monitoring system for remote-based patients. Epilepsy, a chronic brain syndrome characterized by recurrent, unpredictable attacks, affects individuals of all ages. IoT-based seizure monitoring can greatly enhance seizure patients' quality of life. IoT device acquires patient data and transmits it to a computer program so that doctors can examine it. Currently, doctors invest significant manual effort in inspecting Electroencephalograph (EEG) signals to identify seizure activity. However, EEG-based seizure detection algorithms face challenges in real-world scenarios due to non-stationary EEG data and variable seizure patterns among patients and recording sessions. Therefore, a sophisticated computer-based approach is necessary to analyze complex EEG records. In this work, the authors proposed a hybrid approach by combining traditional convolution neural (CN) and recurrent neural networks (RNN) along with an attention mechanism for the automatic recognition of epileptic seizures through EEG signal analysis. This attention mechanism focuses on significant subsets of EEG data for class recognition, resulting in improved model performance. The proposed methods are evaluated using a publicly available UCI epileptic seizure recognition dataset, which consists of five classes: four normal conditions and one abnormal seizure condition. Experimental results demonstrate that the suggested approach achieves an overall accuracy of 97.05% for the five-class EEG recognition data, with an accuracy of 99.52% for binary classification distinguishing seizure cases from normal instances. Furthermore, the proposed intelligent seizure recognition model is compatible with an IoMT (Internet of Medical Things) cloud-based smart healthcare framework.

18.
Diagnostics (Basel) ; 13(23)2023 Nov 21.
Artículo en Inglés | MEDLINE | ID: mdl-38066735

RESUMEN

BACKGROUND: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex and debilitating illness with a significant global prevalence, affecting over 65 million individuals. It affects various systems, including the immune, neurological, gastrointestinal, and circulatory systems. Studies have shown abnormalities in immune cell types, increased inflammatory cytokines, and brain abnormalities. Further research is needed to identify consistent biomarkers and develop targeted therapies. This study uses explainable artificial intelligence and machine learning techniques to identify discriminative metabolites for ME/CFS. MATERIAL AND METHODS: The model investigates a metabolomics dataset of CFS patients and healthy controls, including 26 healthy controls and 26 ME/CFS patients aged 22-72. The dataset encapsulated 768 metabolites into nine metabolic super-pathways: amino acids, carbohydrates, cofactors, vitamins, energy, lipids, nucleotides, peptides, and xenobiotics. Random forest methods together with other classifiers were applied to the data to classify individuals as ME/CFS patients and healthy individuals. The classification learning algorithms' performance in the validation step was evaluated using a variety of methods, including the traditional hold-out validation method, as well as the more modern cross-validation and bootstrap methods. Explainable artificial intelligence approaches were applied to clinically explain the optimum model's prediction decisions. RESULTS: The metabolomics of C-glycosyltryptophan, oleoylcholine, cortisone, and 3-hydroxydecanoate were determined to be crucial for ME/CFS diagnosis. The random forest model outperformed the other classifiers in ME/CFS prediction using the 1000-iteration bootstrapping method, achieving 98% accuracy, precision, recall, F1 score, 0.01 Brier score, and 99% AUC. According to the obtained results, the bootstrap validation approach demonstrated the highest classification outcomes. CONCLUSION: The proposed model accurately classifies ME/CFS patients based on the selected biomarker candidate metabolites. It offers a clear interpretation of risk estimation for ME/CFS, aiding physicians in comprehending the significance of key metabolomic features within the model.

19.
Life (Basel) ; 13(6)2023 May 29.
Artículo en Inglés | MEDLINE | ID: mdl-37374060

RESUMEN

The domestication of animals and the cultivation of crops have been essential to human development throughout history, with the agricultural sector playing a pivotal role. Insufficient nutrition often leads to plant diseases, such as those affecting rice crops, resulting in yield losses of 20-40% of total production. These losses carry significant global economic consequences. Timely disease diagnosis is critical for implementing effective treatments and mitigating financial losses. However, despite technological advancements, rice disease diagnosis primarily depends on manual methods. In this study, we present a novel self-attention network (SANET) based on the ResNet50 architecture, incorporating a kernel attention mechanism for accurate AI-assisted rice disease classification. We employ attention modules to extract contextual dependencies within images, focusing on essential features for disease identification. Using a publicly available rice disease dataset comprising four classes (three disease types and healthy leaves), we conducted cross-validated classification experiments to evaluate our proposed model. The results reveal that the attention-based mechanism effectively guides the convolutional neural network (CNN) in learning valuable features, resulting in accurate image classification and reduced performance variation compared to state-of-the-art methods. Our SANET model achieved a test set accuracy of 98.71%, surpassing that of current leading models. These findings highlight the potential for widespread AI adoption in agricultural disease diagnosis and management, ultimately enhancing efficiency and effectiveness within the sector.

20.
Healthcare (Basel) ; 10(8)2022 Aug 22.
Artículo en Inglés | MEDLINE | ID: mdl-36011249

RESUMEN

Home healthcare agencies (HHCAs) provide clinical care and rehabilitation services to patients in their own homes. The organization's rules regulate several connected practitioners, doctors, and licensed skilled nurses. Frequently, it monitors a physician or licensed nurse for the facilities and keeps track of the health histories of all clients. HHCAs' quality of care is evaluated using Medicare's star ratings for in-home healthcare agencies. The advent of technology has extensively evolved our living style. Online businesses' ratings and reviews are the best representatives of organizations' trust, services, quality, and ethics. Using data mining techniques to analyze HHCAs' data can help to develop an effective framework for evaluating the finest home healthcare facilities. As a result, we developed an automated predictive framework for obtaining knowledge from patients' feedback using a combination of statistical and machine learning techniques. HHCAs' data contain twelve performance characteristics that we are the first to analyze and depict. After adequate pattern recognition, we applied binary and multi-class approaches on similar data with variations in the target class. Four prominent machine learning models were considered: SVM, Decision Tree, Random Forest, and Deep Neural Networks. In the binary class, the Deep Neural Network model presented promising performance with an accuracy of 97.37%. However, in the case of multiple class, the random forest model showed a significant outcome with an accuracy of 91.87%. Additionally, variable significance is derived from investigating each attribute's importance in predictive model building. The implications of this study can support various stakeholders, including public agencies, quality measurement, healthcare inspectors, and HHCAs, to boost their performance. Thus, the proposed framework is not only useful for putting valuable insights into action, but it can also help with decision-making.

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