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1.

A gain-of-function mutation in DHT synthesis in castration-resistant prostate cancer.

Chang, Kai-Hsiung; Li, Rui; Kuri, Barbara; Lotan, Yair; Roehrborn, Claus G; Liu, Jiayan; Vessella, Robert; Nelson, Peter S; Kapur, Payal; Guo, Xiaofeng; Mirzaei, Hamid; Auchus, Richard J; Sharifi, Nima.

Cell ; 154(5): 1074-1084, 2013 Aug 29.

Artículo en Inglés | MEDLINE | ID: mdl-23993097

2.

H3K9 methylation drives resistance to androgen receptor-antagonist therapy in prostate cancer.

Baratchian, Mehdi; Tiwari, Ritika; Khalighi, Sirvan; Chakravarthy, Ankur; Yuan, Wei; Berk, Michael; Li, Jianneng; Guerinot, Amy; de Bono, Johann; Makarov, Vladimir; Chan, Timothy A; Silverman, Robert H; Stark, George R; Varadan, Vinay; De Carvalho, Daniel D; Chakraborty, Abhishek A; Sharifi, Nima.

Proc Natl Acad Sci U S A ; 119(21): e2114324119, 2022 05 24.

Artículo en Inglés | MEDLINE | ID: mdl-35584120

3.

3ßHSD activity saturates at physiological substrate concentrations in intact cells.

McManus, Jeffrey M; Chung, Yoon-Mi; Sharifi, Nima.

Prostate ; 83(13): 1306-1309, 2023 09.

Artículo en Inglés | MEDLINE | ID: mdl-37321973

4.

HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma.

Zein, Joe; Gaston, Benjamin; Bazeley, Peter; DeBoer, Mark D; Igo, Robert P; Bleecker, Eugene R; Meyers, Deborah; Comhair, Suzy; Marozkina, Nadzeya V; Cotton, Calvin; Patel, Mona; Alyamani, Mohammad; Xu, Weiling; Busse, William W; Calhoun, William J; Ortega, Victor; Hawkins, Gregory A; Castro, Mario; Chung, Kian Fan; Fahy, John V; Fitzpatrick, Anne M; Israel, Elliot; Jarjour, Nizar N; Levy, Bruce; Mauger, David T; Moore, Wendy C; Noel, Patricia; Peters, Stephen P; Teague, W Gerald; Wenzel, Sally E; Erzurum, Serpil C; Sharifi, Nima.

Proc Natl Acad Sci U S A ; 117(4): 2187-2193, 2020 01 28.

Artículo en Inglés | MEDLINE | ID: mdl-31932420

5.

Sex Hormones and Prostate Cancer.

Auchus, Richard J; Sharifi, Nima.

Annu Rev Med ; 71: 33-45, 2020 01 27.

Artículo en Inglés | MEDLINE | ID: mdl-31613683

6.

5α-Reductase Inhibitors Are Associated with Reduced Risk of SARS-CoV-2 Infection: A Matched-Pair, Registry-Based Analysis.

Lyon, Madison; Li, Jianbo; Cullen, Jennifer; Milinovich, Alex; Kattan, Michael; Jehi, Lara; Sharifi, Nima; Klein, Eric A.

J Urol ; 207(1): 183-189, 2022 01.

Artículo en Inglés | MEDLINE | ID: mdl-34433301

7.

Association of HSD3B1 Genotype and Clinical Outcomes in Postmenopausal Estrogen-Receptor-Positive Breast Cancer.

Flanagan, Meghan R; Doody, David R; Voutsinas, Jenna; Wu, Qian; Banda, Kalyan; Sharifi, Nima; Li, Christopher I; Gadi, Vijayakrishna K.

Ann Surg Oncol ; 29(11): 7194-7201, 2022 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-35776258

8.

Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy.

Li, Zhenfei; Alyamani, Mohammad; Li, Jianneng; Rogacki, Kevin; Abazeed, Mohamed; Upadhyay, Sunil K; Balk, Steven P; Taplin, Mary-Ellen; Auchus, Richard J; Sharifi, Nima.

Nature ; 533(7604): 547-51, 2016 05 26.

Artículo en Inglés | MEDLINE | ID: mdl-27225130

9.

Benefits of Airway Androgen Receptor Expression in Human Asthma.

Zein, Joe G; McManus, Jeffrey M; Sharifi, Nima; Erzurum, Serpil C; Marozkina, Nadzeya; Lahm, Timothy; Giddings, Olivia; Davis, Michael D; DeBoer, Mark D; Comhair, Suzy A; Bazeley, Peter; Kim, Hyun Jo; Busse, William; Calhoun, William; Castro, Mario; Chung, Kian Fan; Fahy, John V; Israel, Elliot; Jarjour, Nizar N; Levy, Bruce D; Mauger, David T; Moore, Wendy C; Ortega, Victor E; Peters, Michael; Bleecker, Eugene R; Meyers, Deborah A; Zhao, Yi; Wenzel, Sally E; Gaston, Benjamin.

Am J Respir Crit Care Med ; 204(3): 285-293, 2021 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-33779531

10.

Uptake of high-density lipoprotein by scavenger receptor class B type 1 is associated with prostate cancer proliferation and tumor progression in mice.

Traughber, C Alicia; Opoku, Emmanuel; Brubaker, Gregory; Major, Jennifer; Lu, Hanxu; Lorkowski, Shuhui Wang; Neumann, Chase; Hardaway, Aimalie; Chung, Yoon-Mi; Gulshan, Kailash; Sharifi, Nima; Brown, J Mark; Smith, Jonathan D.

J Biol Chem ; 295(24): 8252-8261, 2020 06 12.

Artículo en Inglés | MEDLINE | ID: mdl-32358065

11.

Targeting backdoor androgen synthesis through AKR1C3 inhibition: A presurgical hormonal ablative neoadjuvant trial in high-risk localized prostate cancer.

Graham, Laura S; True, Lawrence D; Gulati, Roman; Schade, George R; Wright, Jonathan; Grivas, Petros; Yezefski, Todd; Nega, Katie; Alexander, Katerina; Hou, Wen-Min; Yu, Evan Y; Montgomery, Bruce; Mostaghel, Elahe A; Matsumoto, Alvin A; Marck, Brett; Sharifi, Nima; Ellis, William J; Reder, Nicholas P; Lin, Daniel W; Nelson, Peter S; Schweizer, Michael T.

Prostate ; 81(7): 418-426, 2021 05.

Artículo en Inglés | MEDLINE | ID: mdl-33755225

12.

Androgen Deprivation Therapy in Men with Prostate Cancer Does Not Affect Risk of Infection with SARS-CoV-2.

Klein, Eric A; Li, Jianbo; Milinovich, Alex; Schold, Jesse D; Sharifi, Nima; Kattan, Michael W; Jehi, Lara.

J Urol ; 205(2): 441-443, 2021 02.

Artículo en Inglés | MEDLINE | ID: mdl-32897764

13.

Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer.

Li, Zhenfei; Bishop, Andrew C; Alyamani, Mohammad; Garcia, Jorge A; Dreicer, Robert; Bunch, Dustin; Liu, Jiayan; Upadhyay, Sunil K; Auchus, Richard J; Sharifi, Nima.

Nature ; 523(7560): 347-51, 2015 Jul 16.

Artículo en Inglés | MEDLINE | ID: mdl-26030522

14.

New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis.

Hou, Yuan; Zhao, Junfei; Martin, William; Kallianpur, Asha; Chung, Mina K; Jehi, Lara; Sharifi, Nima; Erzurum, Serpil; Eng, Charis; Cheng, Feixiong.

BMC Med ; 18(1): 216, 2020 07 15.

Artículo en Inglés | MEDLINE | ID: mdl-32664879

15.

Loss of dihydrotestosterone-inactivation activity promotes prostate cancer castration resistance detectable by functional imaging.

Zhu, Ziqi; Chung, Yoon-Mi; Sergeeva, Olga; Kepe, Vladimir; Berk, Michael; Li, Jianneng; Ko, Hyun-Kyung; Li, Zhenfei; Petro, Marianne; DiFilippo, Frank P; Lee, Zhenghong; Sharifi, Nima.

J Biol Chem ; 293(46): 17829-17837, 2018 11 16.

Artículo en Inglés | MEDLINE | ID: mdl-30262668

16.

A PK/PD study of Delta-4 abiraterone metabolite in metastatic castration-resistant prostate cancer patients.

Blanchet, Benoit; Carton, Edith; Alyamani, Mohammad; Golmard, Lisa; Huillard, Olivier; Thomas-Scheomann, Audrey; Vidal, Michel; Goldwasser, François; Sharifi, Nima; Alexandre, Jérôme.

Pharmacol Res ; 136: 56-61, 2018 10.

Artículo en Inglés | MEDLINE | ID: mdl-30142421

17.

Reply by Authors.

Lyon, Madison; Li, Jianbo; Cullen, Jennifer; Milinovich, Alex; Kattan, Michael; Jehi, Lara; Sharifi, Nima; Klein, Eric A.

J Urol ; 207(1): 189, 2022 01.

Artículo en Inglés | MEDLINE | ID: mdl-34587771

18.

ASO Author Reflections: Inheritance of Adrenal Permissive HSD3B1 Genotype Negatively Impacts Outcomes in Hormone Receptor-Positive Postmenopausal Breast Cancer.

Flanagan, Meghan R; Sharifi, Nima; Gadi, Vijayakrishna K.

Ann Surg Oncol ; 29(11): 7202-7203, 2022 10.

Artículo en Inglés | MEDLINE | ID: mdl-35819571

19.

ASO Visual Abstract: Association of HSD3B1 Genotype and Clinical Outcomes in Postmenopausal Estrogen Receptor-Positive Breast Cancer.

Flanagan, Meghan R; Doody, David R; Voutsinas, Jenna; Wu, Qian; Banda, Kalyan; Sharifi, Nima; Li, Christopher I; Gadi, Vijayakrishna K.

Ann Surg Oncol ; 29(11): 7204-7205, 2022 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-35980550

20.

HSD3B1 and resistance to androgen-deprivation therapy in prostate cancer: a retrospective, multicohort study.

Hearn, Jason W D; AbuAli, Ghada; Reichard, Chad A; Reddy, Chandana A; Magi-Galluzzi, Cristina; Chang, Kai-Hsiung; Carlson, Rachel; Rangel, Laureano; Reagan, Kevin; Davis, Brian J; Karnes, R Jeffrey; Kohli, Manish; Tindall, Donald; Klein, Eric A; Sharifi, Nima.

Lancet Oncol ; 17(10): 1435-1444, 2016 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-27575027

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