Birth after 12 hours of oocyte refrigeration.

OBJECTIVE: To assess cycle outcome after oocyte refrigeration. DESIGN: Case report. SETTING: Private IVF center. PATIENT(S): One couple in a donor oocyte program. INTERVENTION(S): Intracytoplasmic sperm injection and blastocyst culture after refrigeration of oocytes for 12 hours. MAIN OUTCOME MEASURE(S): Birth. RESULT(S): Fourteen two-pronuclei zygotes from 17 metaphase II refrigerated oocytes resulted in transfer of two blastocysts at day 5 and cryopreservation of six excess embryos at day 6. The patient delivered one healthy male baby after 38 weeks' gestation. CONCLUSION(S): The successful outcome of oocyte refrigeration indicates that this protocol could be useful in circumstances in which a delay in obtaining spermatozoa arises.