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1.
Eur J Clin Microbiol Infect Dis ; 43(7): 1469-1474, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-38735888

RESUMEN

Non-cholera Vibrio spp. includes ubiquitous organisms living in aquatic environments. Their occurrence is associated with global warming and meteorological disasters. In May 2023 the Romagna region, Italy, was affected by severe floods. In the following 15 weeks we observed 5 patients with invasive infections caused by V. vulnificus (3/5) and V. harveyi (2/5). All patients (median age 77 years) had medical comorbidities and shared exposure to seawater. Two patients needed surgery; 2 died. In conclusion, we observed an increased burden of Vibrio spp. invasive infections after May 2023 floods, affecting old patients with predisposing medical conditions.


Asunto(s)
Inundaciones , Vibriosis , Humanos , Italia/epidemiología , Anciano , Vibriosis/microbiología , Vibriosis/epidemiología , Masculino , Femenino , Anciano de 80 o más Años , Vibrio/aislamiento & purificación , Vibrio/genética , Estaciones del Año , Persona de Mediana Edad , Agua de Mar/microbiología , Desastres
2.
Eur Rev Med Pharmacol Sci ; 24(3): 1428-1434, 2020 02.
Artículo en Inglés | MEDLINE | ID: mdl-32096192

RESUMEN

OBJECTIVE: We propose a revised flow chart of spinal infection multidisciplinary management project (SIMP) aimed to standardize the diagnostic process and management of spinal tuberculosis (TB). MATERIALS AND METHODS: We reviewed data from all TB cases with osteoarticular involvement treated at a large tertiary teaching hospital in Bologna, Northern Italy, from January 2013 to December 2017. We cross-linked notified osteoarticular TB cases with SIMP database and we analysed clinical, diagnostic, and treatment data of all cases managed by SIMP. RESULTS: Osteoarticular TB accounted for the 7.8% (n=40) of all TB cases notified between 2013 and 2017 (N=513). Among the identified cases, 52% (n=21/40) had spine involvement: all were enrolled and evaluated by SIMP multidisciplinary group. Females accounted for 57% (12/21) of patients, the median age was 52 years (range 24-82). In the 67% (n=14/21) of cases, the major clinical symptom of spinal TB was back pain reported for a median of 4.5 months (range 1-12 months) before hospital admission. The interferon gamma release assay was positive in 75% (n=16/21) of patients. All patients performed MRI with gadolinium, which indicated spondylodiscitis in 90%. 18F-FDG-PET/CT revealed average maximum standardized uptake value (SUV max) of 12.54 (range 5.3-22) in 17/19 (89.5%). Bacteriological confirmation of TB was obtained in 86% of cases (n=18/21). One-third of patients (7/21) underwent surgery and 95% successfully completed the anti-TB treatment. CONCLUSIONS: Our data reveal that a multidisciplinary approach to spine tuberculosis facilitates early and accurate diagnosis and can improve medical and surgical management of this disease.


Asunto(s)
Manejo de la Enfermedad , Grupo de Atención al Paciente , Diseño de Software , Tuberculosis de la Columna Vertebral/diagnóstico por imagen , Tuberculosis de la Columna Vertebral/terapia , Adulto , Anciano , Anciano de 80 o más Años , Antituberculosos/uso terapéutico , Femenino , Humanos , Relaciones Interprofesionales , Masculino , Persona de Mediana Edad , Tuberculosis de la Columna Vertebral/sangre
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