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1.
J Synchrotron Radiat ; 23(Pt 5): 1110-7, 2016 09 01.
Artículo en Inglés | MEDLINE | ID: mdl-27577764

RESUMEN

A compact high-speed X-ray atomic force microscope has been developed for in situ use in normal-incidence X-ray experiments on synchrotron beamlines, allowing for simultaneous characterization of samples in direct space with nanometric lateral resolution while employing nanofocused X-ray beams. In the present work the instrument is used to observe radiation damage effects produced by an intense X-ray nanobeam on a semiconducting organic thin film. The formation of micrometric holes induced by the beam occurring on a timescale of seconds is characterized.

2.
J Synchrotron Radiat ; 22(6): 1364-71, 2015 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-26524300

RESUMEN

A fast atomic force microscope (AFM) has been developed that can be installed as a sample holder for grazing-incidence X-ray experiments at solid/gas or solid/liquid interfaces. It allows a wide range of possible investigations, including soft and biological samples under physiological conditions (hydrated specimens). The structural information obtained using the X-rays is combined with the data gathered with the AFM (morphology and mechanical properties), providing a unique characterization of the specimen and its dynamics in situ during an experiment. In this work, lipid monolayers and bilayers in air or liquid environment have been investigated by means of AFM, both with imaging and force spectroscopy, and X-ray reflectivity. In addition, this combination allows the radiation damage induced by the beam on the sample to be studied, as has been observed on DOPC and DPPC supported lipid bilayers under physiological conditions.


Asunto(s)
Tecnología de Fibra Óptica/instrumentación , Membrana Dobles de Lípidos/química , Micromanipulación/instrumentación , Microscopía de Fuerza Atómica/instrumentación , Manejo de Especímenes/instrumentación , Difracción de Rayos X/instrumentación , Diseño de Equipo , Análisis de Falla de Equipo , Integración de Sistemas
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