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1.
Int J Eat Disord ; 54(3): 409-421, 2021 03.
Artículo en Inglés | MEDLINE | ID: mdl-33191499

RESUMEN

OBJECTIVE: This study examined factors related to hospital length of stay (LOS), reported referral on discharge, and hospital readmission, for children and adolescents (C&A) admitted to public hospitals for anorexia nervosa (AN), in a large health jurisdiction in Australia. METHOD: Sociodemographic, illness, treatment, and hospital factors associated with LOS, reported referral to post-hospital treatment, and readmission within 28 days were analyzed for C&A with AN admitted to all New South Wales public hospitals in 2017, using median, multinomial logit and logit models. The sample comprised 289 admissions by 200 C&A aged 9-18 years with a primary or secondary diagnosis of AN. RESULTS: AN as a primary diagnosis and the presence of some physical and mental co-occurring conditions (e.g., malnutrition and obsessive-compulsive disorders) conferred a longer LOS. The majority of admissions were recorded being referred to primary care physicians (59.86%) and relatively small numbers to outpatient mental health services (5.54%) or outpatient eating disorder services (8.30%), with age, area socioeconomic status, and illness factors related to referral type. Male, low socioeconomic status, the presence of some co-occurring illnesses (e.g., adjustment disorder and viral infection), and rural or remote locations increased the likelihood of readmission. DISCUSSION: The findings have implications for service design, in particular the pathway to care from hospital into community for AN. Targeted interventions should consider recognizing and treating physical co-occurring illnesses at presentation to the health system, ensuring appropriate referral to community services, and providing services in socioeconomically disadvantaged and rural or remote areas.


Asunto(s)
Anorexia Nerviosa , Readmisión del Paciente , Adolescente , Anorexia Nerviosa/epidemiología , Anorexia Nerviosa/terapia , Niño , Humanos , Tiempo de Internación , Masculino , Alta del Paciente , Derivación y Consulta
2.
Eur Eat Disord Rev ; 26(1): 29-37, 2018 01.
Artículo en Inglés | MEDLINE | ID: mdl-29034536

RESUMEN

This longitudinal study explored family functioning and relationship quality for adolescents with severe anorexia nervosa (AN). An important outcome given healthy family functioning supports effective adolescent development. Fifty-four female adolescents and their parents, treated with family-based treatment after inpatient admission, and 49 non-clinical age-matched adolescents and their parents were compared at assessment and 6 months after session 20. At baseline, AN group mothers and fathers reported poorer family function. AN adolescents were notably similar to controls, reporting poorer function in only one domain. There were no changes for adolescents, an improvement for mothers in the AN group, but an increase in perceived impairment for fathers in both groups, with AN fathers more affected. The similarity in adolescent reports and the increase for fathers over time may indicate that normal adolescent family processes occur even in the midst of serious illness. There is a need to provide intervention to ameliorate the impact of treatment on parents. Copyright © 2017 John Wiley & Sons, Ltd and Eating Disorders Association.


Asunto(s)
Anorexia Nerviosa/terapia , Terapia Familiar , Familia/psicología , Relaciones Padres-Hijo , Adolescente , Anorexia Nerviosa/psicología , Estudios de Casos y Controles , Niño , Femenino , Humanos , Estudios Longitudinales , Masculino , Índice de Severidad de la Enfermedad , Adulto Joven
3.
Int J Eat Disord ; 50(4): 433-436, 2017 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-28393398

RESUMEN

OBJECTIVE: Examine relationships between parental mealtime strategies used in the family meal session of family-based treatment (FBT) and adolescent outcomes at EOT (session 20). METHOD: Eighteen families with an adolescent receiving FBT-AN participated. Parental strategies during videoed family meals were assessed using a family mealtime coding system. Change scores were calculated for both adolescent %EBW and EDE scores. RESULTS: Increased use of parental direct and non-direct eating prompts during the family meal was associated with greater adolescent weight gain at EOT. Use of parental mealtime strategies was not associated with any significant change in adolescent eating psychopathology at EOT. DISCUSSION: Parental verbal eating prompts during the family meal may be effective in promoting short-term weight gain. During the family meal session, parents should be encouraged to maintain a direct focus on their adolescent child's eating behaviour which may assist their child with food consumption and potential weight gain. Further research examining food-based interactions among parents and their adolescent child with AN is needed. © 2016 Wiley Periodicals, Inc.(Int J Eat Disord 2017; 50:433-436).


Asunto(s)
Anorexia Nerviosa/terapia , Terapia Familiar/métodos , Comidas , Relaciones Padres-Hijo , Padres/psicología , Adolescente , Anorexia Nerviosa/psicología , Ingestión de Alimentos/psicología , Femenino , Humanos , Masculino , Resultado del Tratamiento , Aumento de Peso
4.
Int J Eat Disord ; 49(11): 1023-1026, 2016 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-27270494

RESUMEN

OBJECTIVE: Anorexia nervosa (AN) is a severe psychiatric illness with little evidence supporting treatment in adults. Among adolescents with AN, family-based treatment (FBT) is considered first-line outpatient approach, with a growing evidence base. However, research on FBT has stemmed from specialist services in research/public health settings. This study investigated the effectiveness of FBT in a case series of adolescent AN treated in a private practice setting. METHOD: Thirty-four adolescents with full or partial AN, diagnosed according to DSM-IV criteria, participated, and were assessed at pretreatment and post-treatment. Assessments included change in % expected body weight, mood, and eating pathology. RESULTS: Significant weight gain was observed from pretreatment to post-treatment. 45.9% of the sample demonstrated full weight restoration and a further 43.2% achieved partial weight-based remission. Missing data precluded an examination of change in mood and ED psychopathology. DISCUSSION: Effective dissemination across different service types is important to the wider availability of evidence-based treatments. These weight restoration data lend preliminary support to the implementation of FBT in real world treatment settings. © 2016 Wiley Periodicals, Inc. (Int J Eat Disord 2016; 49:1023-1026).


Asunto(s)
Anorexia Nerviosa/terapia , Terapia Familiar , Aumento de Peso , Adolescente , Anorexia Nerviosa/fisiopatología , Peso Corporal , Manual Diagnóstico y Estadístico de los Trastornos Mentales , Femenino , Humanos , Masculino , Pacientes Ambulatorios , Práctica Privada , Inducción de Remisión , Proyectos de Investigación
5.
Int J Eat Disord ; 48(7): 919-22, 2015 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-26488111

RESUMEN

OBJECTIVE: To Identify whether early weight gain in family-based treatment (FBT) predicted greater weight and remission at end of FBT and 12-month follow-up. METHOD: Eighty-two adolescents, with anorexia nervosa, participated in a randomized control trial comparing brief hospitalization for medical stabilization and hospitalization for weight restoration to 90% expected body weight (EBW) (1:1), followed by 20 sessions of FBT. Sixty-nine completed trial protocol. Receiver operating characteristic analyses were conducted investigating whether early weight-gain in FBT predicted outcomes at end of FBT and 12-month follow-up. Participants were analyzed according to their original randomization and as a combined set. Binary logistic regression was used to control for randomization arm effect in combined set analysis. RESULTS: Weight gain greater than 1.8 kg at FBT Session 4 predicted greater %EBW (99.18 SD = 6.93 vs. 92.79 SD = 7.74, p < .05) and remission at end of FBT (46% vs. 11%, p < .05) and at 12-month follow-up (64% vs. 36%, p = .05). Binary logistic regression confirmed weight gain greater than 1.8 kg predicted remission (p < .05) while treatment arm randomization did not add significantly to the model. DISCUSSION: Early weight gain has potential to distinguish likely responders in FBT from those who may need more intensive intervention to achieve remission offering the potential to improve outcomes.


Asunto(s)
Anorexia Nerviosa/terapia , Terapia Familiar/métodos , Adolescente , Peso Corporal , Femenino , Estudios de Seguimiento , Humanos , Modelos Logísticos , Masculino , Curva ROC , Inducción de Remisión , Resultado del Tratamiento , Aumento de Peso
6.
Int J Eat Disord ; 48(1): 72-80, 2015 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-24965701

RESUMEN

OBJECTIVE: To examine the range and frequency of parental mealtime strategies used during the family meal session of Family-Based Treatment (FBT) for adolescent anorexia nervosa, and to explore the relationships between parental mealtime strategies, mealtime emotional tone and parental 'success' at encouraging adolescent food consumption. METHOD: Participants were 21 families with a child aged between 12 and 18 years receiving FBT for adolescent anorexia nervosa. Video recordings of the family meal session (FBT session two) were coded using the Family Mealtime Coding System adapted in this study for use with adolescents (FMCS-A) to identify frequency of parental strategies, emotional tone of the meal (measured by adolescent positive and negative vocalisations) and frequency of prompted mouthfuls consumed by the adolescent (measured by the number of mouthfuls consumed by the adolescent immediately following parental interactions). RESULTS: A range of parental mealtime strategies were in use. Those used repeatedly included direct eating prompts, non-direct eating prompts, physical prompts, and providing information or food-related choices. Several parental mealtime strategies (direct and non-direct eating prompts) were found to be consistently associated with the tone of adolescents' vocalisations and the number of mouthfuls consumed in response to a parental prompt. DISCUSSION: Despite associations with negativity from the adolescent, the use of food-related prompts (both verbal and physical) seems to be associated with increased eating. This indicates the potentially important role of parental control of eating. Following replication, these findings might provide a focus for therapists when supporting and coaching parents during the family meal session.


Asunto(s)
Conducta del Adolescente/psicología , Anorexia Nerviosa/psicología , Ingestión de Alimentos/psicología , Comidas , Relaciones Padres-Hijo , Responsabilidad Parental , Adolescente , Niño , Femenino , Humanos , Masculino , Grabación en Video
7.
Eur Eat Disord Rev ; 23(1): 77-85, 2015 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-25469661

RESUMEN

OBJECTIVE: The family meal is an integral component of Maudsley family-based treatment for anorexia nervosa. The aim of this study was to determine whether there are different types of family meal, as suggested in the treatment manual, and whether within session processes differ according to meal type. METHOD: Thirty video-recorded family meal sessions from a randomised controlled trial were transcribed and analysed using thematic analysis. RESULTS: Analyses revealed two types of family meal. In the first, the patient ate one mouthful more than they were willing to eat. This meal type was characterised by processes that were consistent with the Maudsley model. In the second, the patient ate what was asked of them with little to no difficulty. Therapist and family avoidance differentiated this meal type from the first. DISCUSSION: The current findings, along with the existing theory, suggest that avoidance may have reduced the therapeutic impact of the meal for many families. Strategies to challenge therapist and family avoidance are suggested. Copyright © 2014 John Wiley & Sons, Ltd and Eating Disorders Association.


Asunto(s)
Atención Ambulatoria , Anorexia Nerviosa/terapia , Terapia Familiar , Psicoterapia/métodos , Anorexia Nerviosa/psicología , Ingestión de Alimentos , Trastornos de Alimentación y de la Ingestión de Alimentos/psicología , Trastornos de Alimentación y de la Ingestión de Alimentos/terapia , Femenino , Personal de Salud , Humanos , Masculino , Investigación Cualitativa , Ensayos Clínicos Controlados Aleatorios como Asunto , Resultado del Tratamiento
8.
Int J Eat Disord ; 45(4): 609-14, 2012 May.
Artículo en Inglés | MEDLINE | ID: mdl-22270977

RESUMEN

OBJECTIVE: Family-based treatment for anorexia nervosa (FBT) has demonstrated efficacy in the treatment of adolescents with anorexia nervosa (AN) in a number of randomized control trials (RCT). The aim of the current research was to determine whether adherence to the key components of the model as outlined in the treatment manual predict weight gain or dropout. METHOD: The 59 participants were under 19 years and had AN for less than 3 years. Five core treatment objectives and working alliance were measured across 20 sessions of FBT. RESULTS: The core objectives of parents taking control, being united, not criticizing the patient and externalizing the illness predicted greater weight gain. Sibling support did not predict weight gain. The relationship between therapeutic alliance and weight gain was positive for mothers but negative for fathers. Dropout was predicted by low control and poor maternal-therapeutic alliance. DISCUSSION: The results of this study lend further support for the efficacy of the FBT, demonstrating that the principles guiding clinical practice are those which lead to weight gain. The finding that parental control is the central predictor of change can also support the development of augmentations to the model.


Asunto(s)
Anorexia Nerviosa/terapia , Terapia Familiar/métodos , Aumento de Peso , Adolescente , Anorexia Nerviosa/psicología , Femenino , Humanos , Masculino , Resultado del Tratamiento
9.
Nurs Times ; 108(8): 20-1, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-22458081

RESUMEN

Rates of sexually transmitted infections among young people aged 16-24 years have soared in recent years. Opportunistic screening for chlamydia and other STIs identifies asymptomatic infection but encouraging this group to take up screening remains a major challenge. National guidance recommends structured one-to-one discussions with young people to achieve behavioural change. Although opportunities for this are rare, the sexual health outreach team in Nottingham has developed an interactive educational module for use with groups of young people and combined it with sexual health screening, with initial positive results.


Asunto(s)
Educación en Salud/organización & administración , Tamizaje Masivo/organización & administración , Educación Sexual/organización & administración , Enfermedades de Transmisión Sexual/enfermería , Enfermedades de Transmisión Sexual/prevención & control , Adolescente , Enfermería Basada en la Evidencia , Femenino , Humanos , Masculino , Evaluación de Programas y Proyectos de Salud , Reino Unido , Adulto Joven
10.
J Med Radiat Sci ; 69(4): 448-455, 2022 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-35762562

RESUMEN

INTRODUCTION: Head and neck cancer (HNC) patients are at risk of weight change, due to inadequate nutrition intake or dehydration, when receiving radiotherapy (RT). This study aimed to develop methodology to measure water content changes on magnetic resonance imaging (MRI) scans of the head and neck region over the course of RT. METHODS: Retrospective datasets of 54 patients were analysed. Eligible patients had been treated for HNC with cisplatin chemoradiation (CRT) or RT alone and underwent a minimum of 2 MRI scans from weeks 0, 3 and 6 of their treatment. Anatomical regions consisting of ≥90% water, on T2-weighted DIXON MRI sequences, were contoured. Water volume changes of all patients were evaluated, within an anatomically standardised external volume, by comparing the absolute water fraction volume (cc) (VEx90WF) and relative water fraction volume (%) (RelVEx90WF) at weeks 0 and 6 of RT. RESULTS: There was a statistically significant difference between the RelVEx90WF at weeks 0 and 6 (P = 0.005). However, no statistically significant difference was identified between weeks 0 and 6 VEx90WF (P = 0.064). There were no statistically significant differences identified between patients who received CRT versus RT alone. CONCLUSION: This study developed a novel method for measuring changes in water fraction volumes over time, using T2-weighted DIXON MRIs. The methodology created in this study requires further validation through phantom imaging, with known fat and water values.


Asunto(s)
Deshidratación , Neoplasias de Cabeza y Cuello , Humanos , Estudios Retrospectivos , Neoplasias de Cabeza y Cuello/diagnóstico por imagen , Neoplasias de Cabeza y Cuello/radioterapia , Imagen por Resonancia Magnética/métodos , Agua
11.
J Diabetes Complications ; 36(5): 108188, 2022 05.
Artículo en Inglés | MEDLINE | ID: mdl-35382966

RESUMEN

BACKGROUND: Liraglutide is an effective treatment for the management of type 2 diabetes mellitus (T2DM). In addition to glycemic control and potential cardioprotective effects, recent studies suggest a possible role for liraglutide in the inhibition of platelet reactivity, further attenuating atherothrombotic risk in patients with T2DM. We evaluated the in-vivo antiplatelet effect of liraglutide in T2DM patients without macrovascular disease or concurrent anti-platelet therapy. METHODS: A double-blind, placebo-controlled pilot study of 16 T2DM patients, 51-69 y/o, (mean age 60.4 y/o, 63.0% male) randomised to receive liraglutide (1.8 mg/day) or placebo (saline) for 6 months was conducted. Platelet aggregation studies at baseline and after initiation of the study intervention: days 1, 7, and 14 and months 1, 3 and 6 were performed. RESULTS: Liraglutide (n = 7) and placebo (n = 9) treated patients demonstrated normal platelet aggregation responses although transient and significant attenuation in maximum slope of platelet aggregation in response to collagen (p ≤ 0.05), arachidonic acid (p ≤ 0.05) and ADP (p ≤ 0.02) was observed in liraglutide compared to placebo treated patients in the first week. CONCLUSIONS: In this pilot study of patients with T2DM liraglutide treatment was associated with a significant, early and transient decrease in maximum slope of platelet aggregation. The clinical significance of this effect is currently unknown and may warrant further investigation. CLINICAL TRIAL REGISTRATION NUMBER: UTN 1111-1181-9567.


Asunto(s)
Diabetes Mellitus Tipo 2 , Liraglutida , Diabetes Mellitus Tipo 2/inducido químicamente , Diabetes Mellitus Tipo 2/complicaciones , Diabetes Mellitus Tipo 2/tratamiento farmacológico , Método Doble Ciego , Femenino , Humanos , Hipoglucemiantes/farmacología , Hipoglucemiantes/uso terapéutico , Liraglutida/farmacología , Liraglutida/uso terapéutico , Masculino , Persona de Mediana Edad , Proyectos Piloto
12.
J Eat Disord ; 10(1): 121, 2022 Aug 18.
Artículo en Inglés | MEDLINE | ID: mdl-35978344

RESUMEN

INTRODUCTION: The prevalence of eating disorders is high in people with higher weight. However, despite this, eating disorders experienced by people with higher weight have been consistently under-recognised and under-treated, and there is little to guide clinicians in the management of eating disorders in this population. AIM: The aim of this guideline is to synthesise the current best practice approaches to the management of eating disorders in people with higher weight and make evidence-based clinical practice recommendations. METHODS: The National Eating Disorders Collaboration Steering Committee auspiced a Development Group for a Clinical Practice Guideline for the treatment of eating disorders for people with higher weight. The Development Group followed the 'Guidelines for Guidelines' process outlined by the National Health and Medical Research Council and aim to meet their Standards to be: 1. relevant and useful for decision making; 2. transparent; 3. overseen by a guideline development group; 4. identifying and managing conflicts of interest; 5. focused on health and related outcomes; 6. evidence informed; 7. making actionable recommendations; 8. up-to-date; and, 9. accessible. The development group included people with clinical and/or academic expertise and/or lived experience. The guideline has undergone extensive peer review and consultation over an 18-month period involving reviews by key stakeholders, including experts and organisations with clinical academic and/or lived experience. RECOMMENDATIONS: Twenty-one clinical recommendations are made and graded according to the National Health and Medical Research Council evidence levels. Strong recommendations were supported for psychological treatment as a first-line treatment approach adults (with bulimia nervosa or binge-eating disorder), adolescents and children. Clinical considerations such as weight stigma, interprofessional collaborative practice and cultural considerations are also discussed. CONCLUSIONS: This guideline will fill an important gap in the need to better understand and care for people experiencing eating disorders who also have higher weight. This guideline acknowledges deficits in knowledge and consequently the reliance on consensus and lower levels of evidence for many recommendations, and the need for research particularly evaluating weight-neutral and other more recent approaches in this field.


The objective of this project was to develop recommendations and clinical considerations to guide clinicians in the management of people experiencing eating disorders who also have higher weight. A Guideline Development Group was formed containing members with academic and/or clinical expertise and people with a lived experience of eating disorder. The guideline was not only informed by reviews of the scientific literature but also clinical expertise and lived expertise. This guideline has undergone extensive review and consultation over an 18-month period involving reviews by key stakeholders, including experts and organisations with clinical, academic and/or lived expertise. The guideline outlines a set of recommendations for clinical practice including the strong recommendation for psychological treatment to be offered as the first treatment for an eating disorder in people who are of higher weight. Considerations in clinical practice including weight stigma, care by professionals from disparate disciplines, and cultural considerations are also discussed. The Guideline Development Group acknowledges a lack of available research evidence specific to people experiencing an eating disorder who are also of higher weight and consequently some recommendations relied on consensus of group members taking into account the expert reviews. The Group also identified areas where additional research is necessary such as research evaluating weigh-neutral and other more recent approached in the field.

13.
Radiother Oncol ; 161: 29-34, 2021 08.
Artículo en Inglés | MEDLINE | ID: mdl-34052341

RESUMEN

BACKGROUND AND PURPOSE: We present the first implementation of Adaptive 4D cone beam CT (4DCBCT) that adapts the image hardware (gantry rotation speed and kV projections) in response to the patient's real-time respiratory signal. Adaptive 4DCBCT was applied on lung cancer patients to reduce the scan time and imaging dose in the ADaptive CT Acquisition for Personalised Thoracic imaging (ADAPT) trial. MATERIALS AND METHODS: The ADAPT technology measures the patient's real-time respiratory signal and uses mathematical optimisation and external circuitry attached to the linear accelerator to modulate the gantry rotation speed and kV projection rate to reduce scan times and imaging dose. For each patient, ADAPT scans were acquired on two treatment fractions and reconstructed with a motion compensated reconstruction algorithm and compared to the current state-of-the-art four-minute 4DCBCT acquisition (conventional 4DCBCT). We report on the scan time, imaging dose and image quality for the first four adaptive 4DCBCT patients. RESULTS: The ADAPT imaging dose was reduced by 85% and scan times were 73 ± 12 s representing a 70% reduction compared to the 240 s conventional 4DCBCT scan. The contrast-to-noise ratio was improved from 9.2 ± 3.9 with conventional 4DCBCT to 11.7 ± 4.1 with ADAPT. DISCUSSION: The ADAPT trial represents the first time that gantry rotation speed and projection acquisition have been adapted and optimised in real-time in response to changes in the patient's breathing. ADAPT demonstrates substantially reduced scan times and imaging dose for clinical 4DCBCT imaging that could enable more efficient and optimised lung cancer radiotherapy.


Asunto(s)
Tomografía Computarizada Cuatridimensional , Neoplasias Pulmonares , Algoritmos , Tomografía Computarizada de Haz Cónico , Humanos , Neoplasias Pulmonares/diagnóstico por imagen , Neoplasias Pulmonares/radioterapia , Aceleradores de Partículas , Fantasmas de Imagen , Respiración
14.
Phys Med Biol ; 66(7)2021 03 23.
Artículo en Inglés | MEDLINE | ID: mdl-33662943

RESUMEN

Conventional 4DCBCT captures 1320 projections across 4 min. Adaptive 4DCBCT has been developed to reduce imaging dose and scan time. This study investigated reconstruction algorithms that best complement adaptive 4DCBCT acquisition for reducing imaging dose and scan time whilst maintaining or improving image quality compared to conventional 4DCBCT acquisition using real patient data from the first 10 adaptive 4DCBCT patients. Adaptive 4DCBCT was implemented in the ADaptive CT Acquisition for Personalized Thoracic imaging clinical trial. Adaptive 4DCBCT modulates gantry rotation speed and kV acquisition rate in response to the patient's real-time respiratory signal, ensuring even angular spacing between projections at each respiratory phase. We examined the first 10 lung cancer radiotherapy patients that received adaptive 4DCBCT. Fast, 200-projection scans over 60-80 s, and slower, 600-projection scans over ∼240 s, were obtained after routine patient treatment and compared against conventional 4DCBCT acquisition. Adaptive 4DCBCT acquisitions were reconstructed using Feldkamp-Davis-Kress (FDK), McKinnon-Bates (MKB), Motion Compensated FDK (MCFDK) and Motion Compensated MKB (MCMKB) algorithms. Reconstructions were assessed via, Structural SIMilarity (SSIM), Signal-to-Noise-Ratio (SNR), Contrast-to-Noise-Ratio (CNR), Tissue Interface Sharpness of Diaphragm (TIS-D) and Tumor (TIS-T). The 200- and 600-projection adaptive 4DCBCT acquisition corresponded to 85% and 55% reduction in imaging dose, shorter and similar scan times of approximately 90 s and 236 s respectively, compared to conventional 4DCBCT acquisition. 200- and 600-projection adaptive 4DCBCT reconstructions achieved more than 0.900 SSIM relative to conventional 4DCBCT acquisition. Compared to conventional 4DCBCT acquisition, 200-projection adaptive 4DCBCT reconstructions achieved higher SNR, CNR, TIS-T, TIS-D with motion compensated algorithms, MCFDK (208%, 159%, 174%, 247%) and MCMKB (214%, 173%, 266%, 245%) respectively. The 200-projection adaptive 4DCBCT MCFDK- and MCMKB-reconstruction results show image quality improvements are possible even with 85% fewer projections acquired. We established acquisition-reconstruction protocols that provide substantial reductions in imaging time and dose whilst improving image quality.


Asunto(s)
Tomografía Computarizada de Haz Cónico , Tomografía Computarizada Cuatridimensional , Algoritmos , Humanos , Movimiento (Física) , Fantasmas de Imagen , Relación Señal-Ruido
15.
Artículo en Inglés | MEDLINE | ID: mdl-32566767

RESUMEN

Radiotherapy software messages (sometimes called alerts, pop-up windows, alarms, or error messages) to the user appear continuously on computer screens. These software messages sometimes require decisions to be made as to the next appropriate action. However, mainly these messages are for information only. Dealing with software messages is a well-recognized problem in healthcare and has contributed to catastrophic events both outside and within radiotherapy. The purpose of this work is to highlight the prevalence and raise awareness within the radiotherapy community of such software messages related to external beam radiation therapy procedures at the linear accelerator. Radiation Therapists (RTTs) were asked to record the type and frequency of software message over 50 fractions and for 50 different patients. The data was collected at 6 institutions in the Netherlands using linear accelerators from Elekta, Ltd. and Varian Medical Systems, Inc. Results show that linear accelerator software messages (including record and verify) occur at a rate of about 8.9 messages per patient fraction. This number of software messages is potentially impacting on patient safety as these messages range in level of importance. The impact and potential reduction of these software messages should be the focus of future research and improved implementation.

16.
J Eat Disord ; 8(1): 58, 2020 Nov 02.
Artículo en Inglés | MEDLINE | ID: mdl-33292542

RESUMEN

INTRODUCTION: The Australia & New Zealand Academy for Eating Disorders (ANZAED) recently developed general principles and clinical practice standards recommended for mental health clinicians and dietitians providing treatment for people with eating disorders. Separate mental health practice and training standards were then devised as a foundation for strengthening the workforce and providing guidance to professional training programs and service providers on the minimal standards required for practice in the eating disorder field. RECOMMENDATIONS: The present recommendations for mental health professionals providing eating disorder treatment describe the following practice and training standards: eating disorder treatment foundations (including co-ordination of services, establishing a positive therapeutic alliance, professional responsibility and knowledge of levels of care), assessment, diagnosis, intervention (including evidence-based intervention, managing psychiatric risk and managing co-morbid mental health problems), and monitoring and evaluation. CONCLUSIONS: Further work is required to disseminate these standards to clinicians providing services across Australia to people with eating disorders, and to support adherence in the clinic room where they can translate to improved outcomes for clients. Pathways to supporting adherence include expert supervision of practice, incorporation in training and supervised practice in university settings, and support with checklists that can be used by consumers and referring professionals.

17.
Artículo en Inglés | MEDLINE | ID: mdl-32181375

RESUMEN

Fifteen years of reported incidents were reviewed to provide insight into the effectiveness of an Incident Learning System (ISL). The actual error rate over the 15 years was 1.3 reported errors per 1000 treatment attendances. Incidents were reviewed using a regression model. The average number of incidents per year and the number of incidents per thousand attendances declined over time. Two seven-year periods were considered for analysis and the average for the first period (2005-2011) was 6 reported incidents per 1000 attendances compared to 2 incidents for the later period (2012-2018), p < 0.05. SAC 1 and SAC 2 errors have reduced over time and the reduction could be attributed to the quality assurance aspect of IGRT where the incident is identified prior to treatment delivery rather than after, reducing the severity of any potential incidents. The reasoning behind overall reduction in incident reporting over time is unclear but may be associated to quality and technology initiatives, issues with the ISL itself or a change in the staff reporting culture.

18.
Artículo en Inglés | MEDLINE | ID: mdl-33251344

RESUMEN

INTRODUCTION: While there is evidence to show the positive effects of automation, the impact on radiation oncology professionals has been poorly considered. This study examined radiation oncology professionals' perceptions of automation in radiotherapy planning. METHOD: An online survey link was sent to the chief radiation therapists (RT) of all Australian radiotherapy centres to be forwarded to RTs, medical physicists (MP) and radiation oncologists (RO) within their institution. The survey was open from May-July 2019. RESULTS: Participants were 204 RTs, 84 MPs and 37 ROs (response rates ∼10% of the overall radiation oncology workforce). Respondents felt automation resulted in improvement in consistency in planning (90%), productivity (88%), quality of planning (57%), and staff focus on patient care (49%). When asked about perceived impact of automation, the responses were; will change the primary tasks of certain jobs (66%), will allow staff to do the remaining components of their job more effectively (51%), will eliminate jobs (20%), and will not have an impact on jobs (6%). 27% of respondents believe automation will reduce job satisfaction. 71% of respondents strongly agree/agree that automation will cause a loss of skills, while only 25% strongly agree/agree that the training and education tools in their department are sufficient. CONCLUSION: Although the effect of automation is perceived positively, there are some concerns on loss of skillsets and the lack of training to maintain this. These results highlight the need for continued education to ensure that skills and knowledge are not lost with automation.

19.
J Eat Disord ; 8(1): 63, 2020 Nov 10.
Artículo en Inglés | MEDLINE | ID: mdl-33292546

RESUMEN

INTRODUCTION: Eating disorders are complex to manage, and there is limited guidance around the depth and breadth of knowledge, skills and experience required by treatment providers. The Australia & New Zealand Academy for Eating Disorders (ANZAED) convened an expert group of eating disorder researchers and clinicians to define the clinical practice and training standards recommended for mental health professionals and dietitians providing treatment for individuals with an eating disorder. General principles and clinical practice standards were first developed, after which separate mental health professional and dietitian standards were drafted and collated by the appropriate members of the expert group. The subsequent review process included four stages of consultation and document revision: (1) expert reviewers; (2) a face-to-face consultation workshop attended by approximately 100 health professionals working within the sector; (3) an extensive open access online consultation process; and (4) consultation with key professional and consumer/carer stakeholder organisations. RECOMMENDATIONS: The resulting paper outlines and describes the following eight eating disorder treatment principles: (1) early intervention is essential; (2) co-ordination of services is fundamental to all service models; (3) services must be evidence-based; (4) involvement of significant others in service provision is highly desirable; (5) a personalised treatment approach is required for all patients; (6) education and/or psychoeducation is included in all interventions; (7) multidisciplinary care is required and (8) a skilled workforce is necessary. Seven general clinical practice standards are also discussed, including: (1) diagnosis and assessment; (2) the multidisciplinary care team; (3) a positive therapeutic alliance; (4) knowledge of evidence-based treatment; (5) knowledge of levels of care; (6) relapse prevention; and (7) professional responsibility. CONCLUSIONS: These principles and standards provide guidance to professional training programs and service providers on the development of knowledge required as a foundation on which to build competent practice in the eating disorder field. Implementing these standards aims to bring treatment closer to best practice, and consequently improve treatment outcomes, reduce financial cost to patients and services and improve patient quality of life.

20.
Clin Child Psychol Psychiatry ; 24(1): 129-143, 2019 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-30080102

RESUMEN

Maudsley Family-Based Treatment (FBT) is currently the best supported treatment for adolescents with anorexia nervosa (AN); however, little is known about whether it achieves its stated aim in the final phases of promoting the patient's return to an expected developmental trajectory. This study aimed to explore the perspectives of young people and their parents regarding the developmental impact of AN, and the role of FBT in addressing developmental challenges. Young people ( N = 12) who ceased FBT a minimum 1 year prior, and their parents ( N = 12), completed face-to-face semi-structured interviews, and data were analysed using a narrative inquiry method. All the participants described AN as highly disruptive to adolescent development, with phase one of FBT accentuating this experience. In phases two and three, FBT helped facilitate adolescent development in three key ways: Supporting return to adolescent pursuits, facilitating autonomy and providing freedom to develop post-FBT. This study offers preliminary insights into the variety of developmental challenges and needs experienced by families, as well as approaches clinicians can take to supporting development in phases two and three of FBT.


Asunto(s)
Desarrollo del Adolescente , Anorexia Nerviosa/psicología , Anorexia Nerviosa/terapia , Terapia Familiar/métodos , Padres/psicología , Adolescente , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Narrativas Personales como Asunto , Investigación Cualitativa , Adulto Joven
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