Topological transformability and reprogrammability of multistable mechanical metamaterials.

Concepts from quantum topological states of matter have been extensively utilized in the past decade to create mechanical metamaterials with topologically protected features, such as one-way edge states and topologically polarized elasticity. Maxwell lattices represent a class of topological mechanical metamaterials that exhibit distinct robust mechanical properties at edges/interfaces when they are topologically polarized. Realizing topological phase transitions in these materials would enable on-and-off switching of these edge states, opening opportunities to program mechanical response and wave propagation. However, such transitions are extremely challenging to experimentally control in Maxwell topological metamaterials due to mechanical and geometric constraints. Here we create a Maxwell lattice with bistable units to implement synchronized transitions between topological states and demonstrate dramatically different stiffnesses as the lattice transforms between topological phases both theoretically and experimentally. By combining multistability with topological phase transitions, this metamaterial not only exhibits topologically protected mechanical properties that swiftly and reversibly change, but also offers a rich design space for innovating mechanical computing architectures and reprogrammable neuromorphic metamaterials. Moreover, we design and fabricate a topological Maxwell lattice using multimaterial 3D printing and demonstrate the potential for miniaturization via additive manufacturing. These design principles are applicable to transformable topological metamaterials for a variety of tasks such as switchable energy absorption, impact mitigation, wave tailoring, neuromorphic metamaterials, and controlled morphing systems.

Helical Structures Mimicking Chiral Seedpod Opening and Tendril Coiling.

Helical structures are ubiquitous in natural and engineered systems across multiple length scales. Examples include DNA molecules, plants' tendrils, sea snails' shells, and spiral nanoribbons. Although this symmetry-breaking shape has shown excellent performance in elastic springs or propulsion generation in a low-Reynolds-number environment, a general principle to produce a helical structure with programmable geometry regardless of length scales is still in demand. In recent years, inspired by the chiral opening of Bauhinia variegata's seedpod and the coiling of plant's tendril, researchers have made significant breakthroughs in synthesizing state-of-the-art 3D helical structures through creating intrinsic curvatures in 2D rod-like or ribbon-like precursors. The intrinsic curvature results from the differential response to a variety of external stimuli of functional materials, such as hydrogels, liquid crystal elastomers, and shape memory polymers. In this review, we give a brief overview of the shape transformation mechanisms of these two plant's structures and then review recent progress in the fabrication of biomimetic helical structures that are categorized by the stimuli-responsive materials involved. By providing this survey on important recent advances along with our perspectives, we hope to solicit new inspirations and insights on the development and fabrication of helical structures, as well as the future development of interdisciplinary research at the interface of physics, engineering, and biology.

Exposure to ZnO nanoparticles induced blood-milk barrier dysfunction by disrupting tight junctions and cell injury.

Zinc oxide nanoparticles (ZnO-NPs) are one of the most widely used nanomaterials with excellent chemical and biological properties. However, their widespread application has led to increased risk to the natural environment and public health. A growing number of studies have shown that ZnO-NPs deposited in target organs interact with internal barriers to trigger injurious responses. The underlying mechanism of ZnO-NPs on the blood-milk barrier dysfunction remains to be understood. Our results revealed that excessive accumulation of ZnO-NPs induced histopathological injuries in the mammary gland, leading to the distribution of ZnO-NPs in the milk of lactating mice. A prominent diffusion of blood-milk barrier permeability marker, albumin-fluorescein isothiocyanate conjugate (FITC-albumin) was observed at cell-cell junction after ZnO-NPs exposure. Meanwhile, ZnO-NPs weakened the blood-milk barrier function by altering the expression of tight junction proteins. The excessive accumulation of ZnO-NPs also induced inflammatory response by activating the NF-κB and MAPK signaling pathways, leading to the dysfunctional blood-milk barrier. Furthermore, we found that ZnO-NPs led to increased iron accumulation and lipid oxidation, thus increasing oxidative injury and ferroptosis in mammary glands. These results indicated that ZnO-NPs weaken the integrity of the blood-milk barrier by directly affecting tight junctions and cellular injury in different ways.

Gaussian-preserved, non-volatile shape morphing in three-dimensional microstructures for dual-functional electronic devices.

Motile plant structures such as Mimosa pudica leaves, Impatiens glandulifera seedpods, and Dionaea muscipula leaves exhibit fast nastic movements in a few seconds or less. This motion is stimuli-independent mechanical movement following theorema egregium rules. Artificial analogs of tropistic motion in plants are exemplified by shape-morphing systems, which are characterized by high functional robustness and resilience for creating 3D structures. However, all shape-morphing systems developed so far rely exclusively on continuous external stimuli and result in slow response. Here, we report a Gaussian-preserved shape-morphing system to realize ultrafast shape morphing and non-volatile reconfiguration. Relying on the Gaussian-preserved rules, the transformation can be triggered by mechanical or thermal stimuli within a microsecond. Moreover, as localized energy minima are encountered during shape morphing, non-volatile configuration is preserved by geometrically enhanced rigidity. Using this system, we demonstrate a suite of electronic devices that are reconfigurable, and therefore, expand functional diversification.

Dynamically Tunable Friction via Subsurface Stiffness Modulation.

Currently soft robots primarily rely on pneumatics and geometrical asymmetry to achieve locomotion, which limits their working range, versatility, and other untethered functionalities. In this paper, we introduce a novel approach to achieve locomotion for soft robots through dynamically tunable friction to address these challenges, which is achieved by subsurface stiffness modulation (SSM) of a stimuli-responsive component within composite structures. To demonstrate this, we design and fabricate an elastomeric pad made of polydimethylsiloxane (PDMS), which is embedded with a spiral channel filled with a low melting point alloy (LMPA). Once the LMPA strip is melted upon Joule heating, the compliance of the composite structure increases and the friction between the composite surface and the opposing surface increases. A series of experiments and finite element analysis (FEA) have been performed to characterize the frictional behavior of these composite pads and elucidate the underlying physics dominating the tunable friction. We also demonstrate that when these composite structures are properly integrated into soft crawling robots inspired by inchworms and earthworms, the differences in friction of the two ends of these robots through SSM can potentially be used to generate translational locomotion for untethered crawling robots.

Controllable Shape Changing and Tristability of Bilayer Composite.

The programmable shape transition of a two-dimensional sheet to a three-dimensional (3D) structure in response to a variety of external stimuli has recently attracted increasing attention. Among the various shape changing materials, shape memory polymers (SMPs) can fix their temporary shape and/or their length and recover under proper thermal treatment. In this work, we create a bilayer composite by bonding one layer of elastomer with one layer of stretched SMPs, which can undergo a series of shape transitions via the storage and release of internal stresses. The programed shapes are achieved by adjusting the orientation and elongation of the SMPs. Meanwhile, the 3D structures exhibit tristability and can transit between hemihelical, left-handed helical, and right-handed helical shapes. Both theoretical analysis and finite element simulations were conducted to understand the mechanism of shape transformation and used to predict the deformed configuration by adjusting preprogramming parameters. Our work provides a new strategy and design space for fabricating smart reconfigurable structures and paves way for the design and development of bioinspired four-dimensional active matter for a broad range of applications in intelligent materials.