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1.

IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease.

Højen, Jesper Falkesgaard; Kristensen, Marie Louise Vindvad; McKee, Amy S; Wade, Megan Taylor; Azam, Tania; Lunding, Lars P; de Graaf, Dennis M; Swartzwelter, Benjamin J; Wegmann, Michael; Tolstrup, Martin; Beckman, Karsten; Fujita, Mayumi; Fischer, Stephan; Dinarello, Charles A.

Nat Immunol ; 20(9): 1138-1149, 2019 09.

Artículo en Inglés | MEDLINE | ID: mdl-31427775

2.

LAMP3 deficiency affects surfactant homeostasis in mice.

Lunding, Lars P; Krause, Daniel; Stichtenoth, Guido; Stamme, Cordula; Lauterbach, Niklas; Hegermann, Jan; Ochs, Matthias; Schuster, Björn; Sedlacek, Radislav; Saftig, Paul; Schwudke, Dominik; Wegmann, Michael; Damme, Markus.

PLoS Genet ; 17(6): e1009619, 2021 06.

Artículo en Inglés | MEDLINE | ID: mdl-34161347

3.

Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice.

Wenzel, Jan; Hansen, Cathrin E; Bettoni, Carla; Vogt, Miriam A; Lembrich, Beate; Natsagdorj, Rentsenkhand; Huber, Gianna; Brands, Josefine; Schmidt, Kjestine; Assmann, Julian C; Stölting, Ines; Saar, Kathrin; Sedlacik, Jan; Fiehler, Jens; Ludewig, Peter; Wegmann, Michael; Feller, Nina; Richter, Marius; Müller-Fielitz, Helge; Walther, Thomas; König, Gabriele M; Kostenis, Evi; Raasch, Walter; Hübner, Norbert; Gass, Peter; Offermanns, Stefan; de Wit, Cor; Wagner, Carsten A; Schwaninger, Markus.

Proc Natl Acad Sci U S A ; 117(3): 1753-1761, 2020 01 21.

Artículo en Inglés | MEDLINE | ID: mdl-31896584

4.

IL-37 regulates allergic inflammation by counterbalancing pro-inflammatory IL-1 and IL-33.

Schröder, Alexandra; Lunding, Lars P; Zissler, Ulrich M; Vock, Christina; Webering, Sina; Ehlers, Johanna C; Orinska, Zane; Chaker, Adam; Schmidt-Weber, Carsten B; Lang, Niklas J; Schiller, Herbert B; Mall, Marcus A; Fehrenbach, Heinz; Dinarello, Charles A; Wegmann, Michael.

Allergy ; 77(3): 856-869, 2022 03.

Artículo en Inglés | MEDLINE | ID: mdl-34460953

5.

COL4A3 is degraded in allergic asthma and degradation predicts response to anti-IgE therapy.

Weckmann, Markus; Bahmer, Thomas; Sand, Jannie Marie; Rank Rønnow, Sarah; Pech, Martin; Vermeulen, Cornelis; Faiz, Alen; Leeming, Diana Julie; Karsdal, Morten Asser; Lunding, Lars; Oliver, Brian George G; Wegmann, Michael; Ulrich-Merzenich, Gudrun; Juergens, Uwe R; Duhn, Jannis; Laumonnier, Yves; Danov, Olga; Sewald, Katherina; Zissler, Ulrich; Jonker, Marnix; König, Inke; Hansen, Gesine; von Mutius, Erika; Fuchs, Oliver; Dittrich, Anna-Maria; Schaub, Bianca; Happle, Christine; Rabe, Klaus F; van de Berge, Maarten; Burgess, Janette Kay; Kopp, Matthias Volkmar.

Eur Respir J ; 58(6)2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34326188

6.

A prenatally disrupted airway epithelium orchestrates the fetal origin of asthma in mice.

Zazara, Dimitra E; Wegmann, Michael; Giannou, Anastasios D; Hierweger, Alexandra Maximiliane; Alawi, Malik; Thiele, Kristin; Huber, Samuel; Pincus, Maike; Muntau, Ania C; Solano, Maria Emilia; Arck, Petra C.

J Allergy Clin Immunol ; 145(6): 1641-1654, 2020 06.

Artículo en Inglés | MEDLINE | ID: mdl-32305348

7.

The IL-17 receptor IL-17RE mediates polyIC-induced exacerbation of experimental allergic asthma.

Vella, Giovanna; Lunding, Lars; Ritzmann, Felix; Honecker, Anja; Herr, Christian; Wegmann, Michael; Bals, Robert; Beisswenger, Christoph.

Respir Res ; 21(1): 176, 2020 Jul 08.

Artículo en Inglés | MEDLINE | ID: mdl-32641167

8.

The alpha-melanocyte-stimulating hormone acts as a local immune homeostasis factor in experimental allergic asthma.

Webering, Sina; Lunding, Lars Peter; Vock, Christina; Schröder, Alexandra; Gaede, Karoline I; Herzmann, Christian; Fehrenbach, Heinz; Wegmann, Michael.

Clin Exp Allergy ; 49(7): 1026-1039, 2019 07.

Artículo en Inglés | MEDLINE | ID: mdl-30980429

9.

Trained immunity in allergic asthma.

Wegmann, Michael.

J Allergy Clin Immunol ; 151(6): 1471-1473, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-36868321

10.

Tumstatin fragment selectively inhibits neutrophil infiltration in experimental asthma exacerbation.

Nissen, Gyde; Hollaender, Henrike; Tang, Francesca S M; Wegmann, Michael; Lunding, Lars; Vock, Christina; Bachmann, Anna; Lemmel, Solveig; Bartels, Rainer; Oliver, Brian G; Burgess, Janette K; Becker, Tim; Kopp, Matthias V; Weckmann, Markus.

Clin Exp Allergy ; 48(11): 1483-1493, 2018 11.

Artículo en Inglés | MEDLINE | ID: mdl-30028047

11.

Airway remodeling in asthma: what really matters.

Fehrenbach, Heinz; Wagner, Christina; Wegmann, Michael.

Cell Tissue Res ; 367(3): 551-569, 2017 03.

Artículo en Inglés | MEDLINE | ID: mdl-28190087

12.

The NLRP3 inflammasome inhibitor, OLT1177^® , ameliorates experimental allergic asthma in mice.

Lunding, Lars P; Skouras, Damaris B; Vock, Christina; Dinarello, Charles A; Wegmann, Michael.

Allergy ; 77(3): 1035-1038, 2022 03.

Artículo en Inglés | MEDLINE | ID: mdl-34716997

13.

Poly(inosinic-cytidylic) acid-triggered exacerbation of experimental asthma depends on IL-17A produced by NK cells.

Lunding, Lars P; Webering, Sina; Vock, Christina; Behrends, Jochen; Wagner, Christina; Hölscher, Christoph; Fehrenbach, Heinz; Wegmann, Michael.

J Immunol ; 194(12): 5615-25, 2015 Jun 15.

Artículo en Inglés | MEDLINE | ID: mdl-25972482

14.

Il-17A contributes to maintenance of pulmonary homeostasis in a murine model of cigarette smoke-induced emphysema.

Voss, Meike; Wolf, Lisa; Kamyschnikow, Andreas; Wonnenberg, Bodo; Honecker, Anja; Herr, Christian; Lepper, Philipp M; Wegmann, Michael; Menger, Michael D; Bals, Robert; Beisswenger, Christoph.

Am J Physiol Lung Cell Mol Physiol ; 309(2): L188-95, 2015 Jul 15.

Artículo en Inglés | MEDLINE | ID: mdl-26024895

15.

Parallel detection of multiple biomarkers in a point-of-care-competent device for the prediction of exacerbations in chronic inflammatory lung disease.

Röckendorf, Niels; Ramaker, Katrin; Gaede, Karoline; Tappertzhofen, Kristof; Lunding, Lars; Wegmann, Michael; Horbert, Peter; Weber, Karina; Frey, Andreas.

Sci Rep ; 14(1): 12830, 2024 06 04.

Artículo en Inglés | MEDLINE | ID: mdl-38834656

16.

The Dual Role of the Airway Epithelium in Asthma: Active Barrier and Regulator of Inflammation.

Frey, Andreas; Lunding, Lars P; Wegmann, Michael.

Cells ; 12(18)2023 Sep 05.

Artículo en Inglés | MEDLINE | ID: mdl-37759430

17.

Long-term bortezomib treatment reduces allergen-specific IgE but fails to ameliorate chronic asthma in mice.

Wegmann, Michael; Lunding, Lars; Orinska, Zane; Wong, David M; Manz, Rudolf A; Fehrenbach, Heinz.

Int Arch Allergy Immunol ; 158(1): 43-53, 2012.

Artículo en Inglés | MEDLINE | ID: mdl-22212634

18.

IL-17 Cytokines and Chronic Lung Diseases.

Ritzmann, Felix; Lunding, Lars Peter; Bals, Robert; Wegmann, Michael; Beisswenger, Christoph.

Cells ; 11(14)2022 07 06.

Artículo en Inglés | MEDLINE | ID: mdl-35883573

19.

A serological biomarker of type I collagen degradation is related to a more severe, high neutrophilic, obese asthma subtype.

Rønnow, Sarah Rank; Sand, Jannie Marie Bülow; Staunstrup, Line Mærsk; Bahmer, Thomas; Wegmann, Michael; Lunding, Lars; Burgess, Janette; Rabe, Klaus; Sorensen, Grith Lykke; Fuchs, Oliver; Mutius, Erika V; Hansen, Gesine; Kopp, Matthias Volkmar; Karsdal, Morten; Leeming, Diana Julie; Weckmann, Markus.

Asthma Res Pract ; 8(1): 2, 2022 Apr 13.

Artículo en Inglés | MEDLINE | ID: mdl-35418159

20.

Targeting eosinophil biology in asthma therapy.