RESUMEN
Aspirin solution applied locally to the oral cavity produces an analgesic effect on pain induced by electrical stimuli and by knife prick. Spontaneous pain is also relieved. The effect is of a local nature and can be terminated by rinsing the mouth with water, indicating that there is only a loose bond between aspirin and the mucosa. The local nature is also demonstrated by the lack of analgesia in areas of the tongue where exposure to aspirin solution is prevented by separation with a rubber-dam.
Asunto(s)
Analgesia , Aspirina/farmacología , Lengua/efectos de los fármacos , Administración Oral , Adolescente , Adulto , Anciano , Aspirina/administración & dosificación , Evaluación de Medicamentos , Estimulación Eléctrica/efectos adversos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Dolor/etiología , Distribución Aleatoria , Soluciones , Factores de Tiempo , Lengua/fisiología , Lengua/fisiopatologíaRESUMEN
Otoadmittance measurements and air- and bone-conduction thresholds were obtained for 20 subjects who underwent type I tympanoplasty. Component tympanometry, particularly with a high-frequency probe tone, demonstrated that homograft tympanic membrane transplants exhibited more normal function than did temporalis fascia grafts. Audiometric results revealed greater hearing improvement by the homograft transplant group.