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1.

Katanin contributes to interspecies spindle length scaling in Xenopus.

Loughlin, Rose; Wilbur, Jeremy D; McNally, Francis J; Nédélec, François J; Heald, Rebecca.

Cell ; 147(6): 1397-407, 2011 Dec 09.

Artículo en Inglés | MEDLINE | ID: mdl-22153081

2.

Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia.

Varkaris, Andreas; Pazolli, Ermira; Gunaydin, Hakan; Wang, Qi; Pierce, Levi; Boezio, Alessandro A; Bulku, Artemisa; DiPietro, Lucian; Fridrich, Cary; Frost, Adam; Giordanetto, Fabrizio; Hamilton, Erika P; Harris, Katherine; Holliday, Michael; Hunter, Tamieka L; Iskandar, Amanda; Ji, Yongli; Larivée, Alexandre; LaRochelle, Jonathan R; Lescarbeau, André; Llambi, Fabien; Lormil, Brenda; Mader, Mary M; Mar, Brenton G; Martin, Iain; McLean, Thomas H; Michelsen, Klaus; Pechersky, Yakov; Puente-Poushnejad, Erika; Raynor, Kevin; Rogala, Dipali; Samadani, Ramin; Schram, Alison M; Shortsleeves, Kelley; Swaminathan, Sweta; Tajmir, Shahein; Tan, Gege; Tang, Yong; Valverde, Roberto; Wehrenberg, Bryan; Wilbur, Jeremy; Williams, Bret R; Zeng, Hongtao; Zhang, Hanmo; Walters, W Patrick; Wolf, Beni B; Shaw, David E; Bergstrom, Donald A; Watters, James; Fraser, James S.

Cancer Discov ; 14(2): 240-257, 2024 Feb 08.

Artículo en Inglés | MEDLINE | ID: mdl-37916956

3.

Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors.

Taylor, Alexander M; Williams, Bret R; Giordanetto, Fabrizio; Kelley, Elizabeth H; Lescarbeau, André; Shortsleeves, Kelley; Tang, Yong; Walters, W Patrick; Arrazate, Alfonso; Bowman, Christine; Brophy, Erin; Chan, Emily W; Deshmukh, Gauri; Greisman, Jack B; Hunsaker, Thomas L; Kipp, D Randal; Saenz Lopez-Larrocha, Pablo; Maddalo, Danilo; Martin, Iain J; Maragakis, Paul; Merchant, Mark; Murcko, Mark; Nisonoff, Hunter; Nguyen, Vi; Nguyen, Vy; Orozco, Olivia; Owen, Christopher; Pierce, Levi; Schmidt, Molly; Shaw, David E; Smith, Sherri; Therrien, Eric; Tran, John C; Watters, Jim; Waters, Nigel J; Wilbur, Jeremy; Willmore, Lindsay.

J Med Chem ; 66(19): 13384-13399, 2023 Oct 12.

Artículo en Inglés | MEDLINE | ID: mdl-37774359

4.

Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain.

Wilbur, Jeremy D; Hwang, Peter K; Brodsky, Frances M; Fletterick, Robert J.

Acta Crystallogr D Biol Crystallogr ; 66(Pt 3): 314-8, 2010 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-20179344

5.

A comparative analysis of spindle morphometrics across metazoans.

Crowder, Marina E; Strzelecka, Magdalena; Wilbur, Jeremy D; Good, Matthew C; von Dassow, George; Heald, Rebecca.

Curr Biol ; 25(11): 1542-50, 2015 Jun 01.

Artículo en Inglés | MEDLINE | ID: mdl-26004761

6.

Mitotic spindle scaling during Xenopus development by kif2a and importin α.

Wilbur, Jeremy D; Heald, Rebecca.

Elife ; 2: e00290, 2013 Feb 19.

Artículo en Inglés | MEDLINE | ID: mdl-23425906

7.

Cryptic no longer: arrays of CLASP1 TOG domains.

Wilbur, Jeremy D; Heald, Rebecca.

Structure ; 21(6): 869-70, 2013 Jun 04.

Artículo en Inglés | MEDLINE | ID: mdl-23747108

8.

N-terminal phosphorylation of p60 katanin directly regulates microtubule severing.

Whitehead, Evan; Heald, Rebecca; Wilbur, Jeremy D.

J Mol Biol ; 425(2): 214-21, 2013 Jan 23.

Artículo en Inglés | MEDLINE | ID: mdl-23178168

9.

Interplay between spindle architecture and function.

Helmke, Kara J; Heald, Rebecca; Wilbur, Jeremy D.

Int Rev Cell Mol Biol ; 306: 83-125, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-24016524

10.

Clathrin phosphorylation is required for actin recruitment at sites of bacterial adhesion and internalization.

Bonazzi, Matteo; Vasudevan, Lavanya; Mallet, Adeline; Sachse, Martin; Sartori, Anna; Prevost, Marie-Christine; Roberts, Allison; Taner, Sabrina B; Wilbur, Jeremy D; Brodsky, Frances M; Cossart, Pascale.

J Cell Biol ; 195(3): 525-36, 2011 Oct 31.

Artículo en Inglés | MEDLINE | ID: mdl-22042622

11.

Conformation switching of clathrin light chain regulates clathrin lattice assembly.

Wilbur, Jeremy D; Hwang, Peter K; Ybe, Joel A; Lane, Michael; Sellers, Benjamin D; Jacobson, Matthew P; Fletterick, Robert J; Brodsky, Frances M.

Dev Cell ; 18(5): 841-8, 2010 May 18.

Artículo en Inglés | MEDLINE | ID: mdl-20493816

12.

Mutations that alter RcdA surface residues decouple protein localization and CtrA proteolysis in Caulobacter crescentus.

Taylor, James A; Wilbur, Jeremy D; Smith, Stephen C; Ryan, Kathleen R.

J Mol Biol ; 394(1): 46-60, 2009 Nov 20.

Artículo en Inglés | MEDLINE | ID: mdl-19747489

13.

Actin binding by Hip1 (huntingtin-interacting protein 1) and Hip1R (Hip1-related protein) is regulated by clathrin light chain.

Wilbur, Jeremy D; Chen, Chih-Ying; Manalo, Venus; Hwang, Peter K; Fletterick, Robert J; Brodsky, Frances M.

J Biol Chem ; 283(47): 32870-9, 2008 Nov 21.

Artículo en Inglés | MEDLINE | ID: mdl-18790740

14.

New faces of the familiar clathrin lattice.

Wilbur, Jeremy D; Hwang, Peter K; Brodsky, Frances M.

Traffic ; 6(4): 346-50, 2005 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-15752139

15.

Clathrin heavy and light chain isoforms originated by independent mechanisms of gene duplication during chordate evolution.

Wakeham, Diane E; Abi-Rached, Laurent; Towler, Mhairi C; Wilbur, Jeremy D; Parham, Peter; Brodsky, Frances M.

Proc Natl Acad Sci U S A ; 102(20): 7209-14, 2005 May 17.

Artículo en Inglés | MEDLINE | ID: mdl-15883369

16.

The early onset dystonia protein torsinA interacts with kinesin light chain 1.

Kamm, Christoph; Boston, Heather; Hewett, Jeffrey; Wilbur, Jeremy; Corey, David P; Hanson, Phyllis I; Ramesh, Vijaya; Breakefield, Xandra O.

J Biol Chem ; 279(19): 19882-92, 2004 May 07.

Artículo en Inglés | MEDLINE | ID: mdl-14970196

17.

TorsinA in PC12 cells: localization in the endoplasmic reticulum and response to stress.

Hewett, Jeffrey; Ziefer, Philipp; Bergeron, Daniele; Naismith, Teri; Boston, Heather; Slater, Damien; Wilbur, Jeremy; Schuback, Deborah; Kamm, Christoph; Smith, Nicole; Camp, Sara; Ozelius, Laurie J; Ramesh, Vijaya; Hanson, Phyllis I; Breakefield, Xandra O.

J Neurosci Res ; 72(2): 158-68, 2003 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-12671990

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