RESUMEN
Magnetic resonance imaging (MRI) scores for haemophilic arthropathy are useful for evaluation of early and moderate arthropathy. The most recent additive International Prophylaxis Study Group (IPSG) MRI scale for haemophilic arthropathy includes joint effusion. However, it is unknown whether joint effusion is haemophilia specific. Correct interpretation of joint effusion is needed for outcome assessment of prophylactic therapies in haemophilia care. The aim of this study was to compare joint effusion on MRI between young adults with haemophilia and healthy controls. MRI's of both knees and ankles of 26 haemophilic patients (104 joints) and 30 healthy active men (120 joints) were assessed. Scans in both groups were performed in 2009/2010 and 2012 respectively. Joint effusion was measured and scored according to the MRI atlas referred by the IPSG MRI scale for haemophilic arthropathy. Median age of haemophilic patients and healthy controls was 21 and 24 years respectively. In haemophilic patients 23% of knees and 22% of ankles showed joint effusion. Healthy controls had significantly more positive scores for knee effusion (67%, P < 0.01) and a comparable scores for effusion in the ankle (17%). Joint effusion according to criteria of the IPSG MRI scale was observed significantly more often in knees of healthy controls, while findings in ankles were similar. These data suggest that joint effusion in knees and ankles is not haemophilia specific. Inclusion of joint effusion in the MRI scale is expected to reduce its specificity for haemophilic arthropathy.
Asunto(s)
Articulación del Tobillo , Hemofilia A/complicaciones , Hemofilia A/diagnóstico , Interpretación de Imagen Asistida por Computador , Artropatías/complicaciones , Articulación de la Rodilla , Imagen por Resonancia Magnética , Adolescente , Adulto , Estudios de Casos y Controles , Niño , Humanos , Masculino , Índice de Severidad de la Enfermedad , Adulto JovenRESUMEN
Magnetic resonance imaging (MRI) is the most sensitive imaging modality to assess joint lesions, but the clinical relevance of subtle joint changes in haemophilic patients playing sports is unknown. A haemophilia specific MRI score is available, but was never evaluated in physically active healthy controls. It is not known if unexpected MRI changes in young active haemophilic patients are due to sports participation. The aim of this study was to evaluate knees and ankles in a cohort of young active healthy men using a haemophilia specific MRI score to provide context for joint evaluation by MRI in young haemophilic patients. Three Tesla MRI of knees and ankles were performed in 30 healthy men aged 18-26 years, regularly active in sports. MR images were scored by a single independent radiologist, using the International Prophylaxis Study Group additive MRI score. One physiotherapist assessed clinical function using the Haemophilia joint health scores (HJHS). History of complaints or injuries affecting knees and/or ankles, very intensive sports and current sports activities were documented. Median age was 24.3 years (range 19.0-26.4) and median number of sports activities per week was 3 (range 1-4). Six joints (five knees, one ankle) had a history of a sports-related injury. The median HJHS per joint was 0 out of 20 (range 0-1). All joints had a MRI score of 0. These results suggest that regular sports participation or very low HJHS scores are not associated with haemophilia specific MRI changes in knees and ankles.
Asunto(s)
Tobillo/diagnóstico por imagen , Trastornos de la Coagulación Sanguínea Heredados/fisiopatología , Articulación de la Rodilla/diagnóstico por imagen , Índice de Severidad de la Enfermedad , Adulto , Tobillo/fisiopatología , Humanos , Articulación de la Rodilla/fisiopatología , Imagen por Resonancia Magnética , Masculino , Radiografía , Deportes , Adulto JovenRESUMEN
Delirium, the clinical expression of acute encephalopathy, is a common neuropsychiatric syndrome that is related to poor outcomes, such as long-term cognitive impairment. Disturbances of functional brain networks are hypothesized to predispose for delirium. The aim of this study in non-delirious elderly individuals was to investigate whether predisposing risk factors for delirium are associated with fMRI network characteristics that have been observed during delirium. As predisposing risk factors, we studied age, alcohol misuse, cognitive impairment, depression, functional impairment, history of transient ischemic attack or stroke, and physical status. In this multicenter study, we included 554 subjects and analyzed resting-state fMRI data from 222 elderly subjects (63% male, age range: 65-85 year) after rigorous motion correction. Functional network characteristics were analyzed and based on the minimum spanning tree (MST). Global functional connectivity strength, network efficiency (MST diameter) and network integration (MST leaf fraction) were analyzed, as these measures were altered during delirium in previous studies. Linear regression analyses were used to investigate the relation between predisposing delirium risk factors and delirium-related fMRI characteristics, adjusted for confounding and multiple testing. Predisposing risk factors for delirium were not associated with delirium-related fMRI network characteristics. Older age within our elderly cohort was related to global functional connectivity strength (ß = 0.182, p < 0.05), but in the opposite direction than hypothesized. Delirium-related functional network impairments can therefore not be considered as the common mechanism for predisposition for delirium.
Asunto(s)
Delirio , Imagen por Resonancia Magnética , Anciano , Anciano de 80 o más Años , Encéfalo/diagnóstico por imagen , Estudios Transversales , Delirio/epidemiología , Delirio/etiología , Femenino , Humanos , Masculino , Factores de RiesgoRESUMEN
BACKGROUND: Cerebral ischaemia is thought to be an important determinant of cognitive outcome after aneurysmal subarachnoid haemorrhage (aSAH), but the exact relationship is unclear. We studied the effect of ischaemic brain lesions during clinical course on cognitive outcome 2 months after aSAH. METHODS: We studied 74 consecutive patients admitted to the University Medical Center Utrecht who had MRI post-coiling (3-21 days post-aSAH) and neuropsychological examination at 2 months. An ischaemic lesion was defined as hyperintensity on T2-FLAIR and DWI images. We measured both cognitive complaints (subjective) and cognitive functioning (objective). The relationship between ischaemic brain lesions and cognitive outcome was analysed by logistic regression analyses. RESULTS: In 40 of 74 patients (54%), 152 ischaemic lesions were found. The median number of lesions per patient was 2 (1-37) and the median total lesion volume was 0.2 (0-17.4) mL. No difference was found between the group with and the group without ischaemic lesions with respect to the frequency of cognitive complaints. In the group with ischaemic lesions, significantly more patients (55%) showed poor cognitive functioning compared to the group without ischaemic lesions (26%) (OR 3.4, 95% CI 1.3-9.1). We found no relationship between the number and volume of the ischaemic lesions and cognitive functioning. CONCLUSIONS: Ischaemic brain lesions detected on MRI during clinical course after aSAH is a marker for poor cognitive functioning 2 months after aSAH, irrespective of the number or volume of the ischaemic lesions. Network or connectivity studies are needed to better understand the relationship between location of the ischaemic brain lesions and cognitive functioning.
Asunto(s)
Isquemia Encefálica/diagnóstico por imagen , Encéfalo/diagnóstico por imagen , Trastornos del Conocimiento/diagnóstico por imagen , Cognición , Hemorragia Subaracnoidea/diagnóstico por imagen , Anciano , Encéfalo/fisiología , Isquemia Encefálica/complicaciones , Isquemia Encefálica/psicología , Cognición/fisiología , Trastornos del Conocimiento/etiología , Trastornos del Conocimiento/psicología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pruebas Neuropsicológicas , Estudios Prospectivos , Hemorragia Subaracnoidea/complicaciones , Hemorragia Subaracnoidea/psicologíaRESUMEN
We studied whether magnetic resonance (MR) imaging of the brachial plexus is useful to distinguish multifocal motor neuropathy (MMN) from lower motor neuron disease (LMND) and whether abnormalities resemble those of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). We compared MR images of the brachial plexus of nine patients with MMN with scans from five patients with CIDP, eight patients with LMND, and 174 controls. In two patients with MMN, and in three patients with CIDP, the MR images showed an increased signal intensity on the T2-weighted images of the brachial plexus. Two other patients with MMN demonstrated a more focal, increased signal intensity on the T2-weighted images, occurring in one patient only in the axilla, and in the other patient in the axilla and in the ventral rami of the roots. MR images of the brachial plexus of eight patients with LMND were normal. The distribution of the MR imaging abnormalities corresponded with the distribution of symptoms of the patients: asymmetrical in MMN and symmetrical in CIDP. These findings demonstrate that MR imaging abnormalities of the brachial plexus in patients with MMN resemble those seen in CIDP and may be useful to distinguish MMN from LMND.
Asunto(s)
Plexo Braquial/patología , Enfermedades Desmielinizantes/diagnóstico , Imagen por Resonancia Magnética , Enfermedad de la Neurona Motora/diagnóstico , Adulto , Enfermedades Desmielinizantes/terapia , Diagnóstico Diferencial , Femenino , Gadolinio , Humanos , Aumento de la Imagen , Inmunoglobulinas Intravenosas , Masculino , Persona de Mediana Edad , Enfermedad de la Neurona Motora/terapia , Polirradiculoneuropatía/diagnóstico , Polirradiculoneuropatía/terapiaRESUMEN
BACKGROUND: Several patients have been reported with an asymmetric sensory or sensorimotor demyelinating neuropathy not fulfilling the diagnostic criteria for chronic inflammatory demyelinating polyneuropathy or multifocal motor neuropathy. OBJECTIVE: To present the clinical, electrophysiologic, radiologic, and pathologic features of six patients with an asymmetric sensory or sensorimotor demyelinating neuropathy. RESULTS: All six patients were initially affected in only one limb; in four patients the neuropathy progressed to other limbs in an asymmetric fashion during several years. On electrophysiologic examination, evidence of multifocal demyelination and conduction block in motor and sensory nerves was found in all patients. MRI of the brachial plexus revealed swollen nerves and an increased signal intensity on T2-weighted imaging in four patients. A biopsy sample taken from the brachial plexus of one patient revealed evidence of inflammation. All patients showed a beneficial response to IV immunoglobulin treatment. Thirty-four similar patients have been reported previously, many of whom were initially diagnosed as having various other (nontreatable) diseases. CONCLUSIONS: The authors propose calling this neuropathy "multifocal inflammatory demyelinating neuropathy" and considering it as a distinct clinical entity to facilitate early diagnosis of this treatable disorder.
Asunto(s)
Enfermedades Desmielinizantes/diagnóstico , Neuritis/diagnóstico , Adulto , Biopsia , Plexo Braquial/patología , Enfermedades Desmielinizantes/patología , Enfermedades Desmielinizantes/fisiopatología , Diagnóstico Diferencial , Electrofisiología/métodos , Femenino , Humanos , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Enfermedad de la Neurona Motora/diagnóstico , Conducción Nerviosa , Neuritis/patología , Polirradiculoneuropatía Crónica Inflamatoria Desmielinizante/diagnósticoRESUMEN
Using cardiac-gated fast acquisition with multiple excitation (FAME), time curves of the cerebral aqueduct signals were derived in 19 healthy volunteers and 14 patients. A mean curve of the normal subjects was determined during systole. A relatively stable point of time was found at 270 msec after the R-wave supposed to be the reversal of the flow of cerebral-spinal fluid in the aqueduct. Different curves were noticed in complete aqueductal obstruction (n = 2); in other pathologic states, such as cerebral tumor (n = 3), normal pressure hydrocephalus (n = 3), and brain atrophy (n = 1), no different signal time curves were observed. Parameters such as aqueduct diameter, cerebro-spinal fluid volume and brain compliance are probably other important factors in aqueduct liquor flow.
Asunto(s)
Acueducto del Mesencéfalo/patología , Imagen por Resonancia Magnética , Adolescente , Adulto , Anciano , Neoplasias Encefálicas/patología , Líquido Cefalorraquídeo/fisiología , Electrocardiografía , Humanos , Hidrocefalia/patología , Lactante , Imagen por Resonancia Magnética/métodos , Persona de Mediana EdadRESUMEN
RATIONALE AND OBJECTIVES: To evaluate the diagnostic relevance of ipsilateral atrophy of the collateral white matter in the parahippocampal gyrus (ACWMp) and temporal lobe gray/white matter demarcation loss (GWDL) on magnetic resonance imaging in patients with histologically confirmed hippocampal sclerosis. In the second part of this investigation, histologic specimens were analyzed to find an explanation for GWDL. METHODS: Retrospective visual assessment of hippocampal signal intensity and size and of ACWMp and GWDL was performed using 4- to 5-mm coronal T2-weighted spin-echo magnetic resonance images of 80 patients with histologically proven hippocampal sclerosis and of 30 age-matched controls without epilepsy. Frequency of occurrence and likelihood ratios of ACWMp and GWDL were calculated and their contribution to the diagnosis of hippocampal sclerosis was assessed, particularly in patients with no or restricted hippocampal abnormalities (either high signal or smaller size) on magnetic resonance imaging. The second part of the study involved the morphologic histologic assessment of neocortical temporal lobe specimens of all patients. Myelin density was evaluated in specimens of a subgroup of six patients with hippocampal sclerosis and GWDL on MRI and six patients with hippocampal sclerosis without GWDL. RESULTS: ACWMp was found in 68% and GWDL in 65% of patients with hippocampal sclerosis on magnetic resonance imaging. Both features had an infinite positive likelihood ratio. Sixty-two patients (77.5%) had concomitant hippocampal signal increase and smaller size. Eighteen patients (22.5%) had no or restricted hippocampal abnormalities on magnetic resonance imaging. When using ACWMp and GWDL as additional diagnostic parameters, 13 of these 18 patients were more unambiguously diagnosed as having hippocampal sclerosis. No significant morphologic differences were found between GWDL-positive and GWDL-negative specimens. A significantly lower average myelin stain was found in the white matter of the GWDL-positive group compared to the GWDL-negative group. CONCLUSIONS: ACWMp and GWDL can improve the visual diagnosis of hippocampal sclerosis, particularly in patients with no or restricted hippocampal abnormalities. These results suggest that loss of myelin may be the underlying cause of GWDL in association with hippocampal sclerosis.
Asunto(s)
Hipocampo/patología , Imagen por Resonancia Magnética , Lóbulo Temporal/patología , Adolescente , Adulto , Atrofia/diagnóstico , Atrofia/patología , Distribución de Chi-Cuadrado , Niño , Epilepsia del Lóbulo Temporal/diagnóstico , Epilepsia del Lóbulo Temporal/patología , Femenino , Humanos , Funciones de Verosimilitud , Imagen por Resonancia Magnética/estadística & datos numéricos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Esclerosis/diagnóstico , Esclerosis/patología , Sensibilidad y Especificidad , Estadísticas no ParamétricasRESUMEN
RATIONALE AND OBJECTIVES: Definition of optimal magnetic resonance (MR) scanning plane and conventional MR sequence for the detection of mesial temporal sclerosis (MTS). METHODS: Coronal and axial T2-weighted images and axial T2-weighted images parallel to the long axis of the hippocampus (APLAH) and coronal inversion recovery (IR) images were obtained in patients with medically intractable temporal lobe epilepsy in their phase 1 preoperative evaluation. Thirty-three consecutive MR scans were reviewed by a panel of three radiologists. Twenty-three patients had MR abnormalities consistent with MTS, and ten scans were normal. To assess the best single scanning technique, another group of three radiologists, who were masked to all patient data, individually assessed the different planes and sequences of the 33 studies presented separately in a random fashion. For each plane and sequence, the likelihood (L) ratio for the correct diagnosis was determined separately. RESULTS: For all planes considered separately, a likelihood ratio of 4.4 was optimal for the coronal T2-weighted images. The likelihood ratio of APLAH T2 was 2.2; of axial T2, 3.9; of coronal IR, indefinite because of 100% specificity. CONCLUSIONS: For the assessment of MTS, coronal T2-weighted images were considered the best single scanning technique.
Asunto(s)
Epilepsia del Lóbulo Temporal/patología , Imagen por Resonancia Magnética , Lóbulo Temporal/patología , Adolescente , Adulto , Epilepsia del Lóbulo Temporal/diagnóstico , Humanos , Funciones de Verosimilitud , Persona de Mediana Edad , Variaciones Dependientes del Observador , EsclerosisRESUMEN
PURPOSE: To determine whether the lumbosacral junction of the vertebral column can be identified with sonography in newborns and infants and thus serve as a method for counting the lumbar and sacral vertebral bodies. METHODS: In 32 newborns and infants, the number of ossified vertebral bodies distal to the lumbosacral junction was counted with sonography and radiography. RESULTS: Sonographic and radiographic findings agreed in 29 of 32 examinations (91%). CONCLUSIONS: The lordotic transition at the lumbosacral junction can be identified with sonography in the majority of newborns and infants, allowing intraspinal structures to be related to a specific vertebral level.
Asunto(s)
Vértebras Lumbares/diagnóstico por imagen , Sacro/diagnóstico por imagen , Enfermedades de la Columna Vertebral/diagnóstico por imagen , Femenino , Humanos , Lactante , Recién Nacido , Vértebras Lumbares/anatomía & histología , Masculino , Radiografía , Sacro/anatomía & histología , UltrasonografíaRESUMEN
PURPOSE: To determine the frequency of appearance of various MR signs in mesial temporal sclerosis, to determine the optimal scanning planes for their visualization, and to propose a histologic explanation for the diminished demarcation between gray and white matter in the temporal lobe, a frequent MR finding in patients with mesial temporal sclerosis. METHODS: MR scans of 14 surgically treated patients with epilepsy and histologically proven mesial temporal sclerosis were assessed for the presence of six features: feature 1, high signal intensity in the hippocampus; 2, reduced hippocampal size; 3, ipsilateral atrophy of the hippocampal collateral white matter; 4, enlarged temporal horn; 5, reduced gray-white matter demarcation in the temporal lobe; and 6, decreased temporal lobe size. RESULTS: Feature 1 was present in 14 patients and was best appreciated on the T2-weighted images in planes parallel to the long axes of the hippocampi. Feature 2, present in 12 patients, and feature 6, present in 9 patients, were optimally seen in the coronal planes and on the inversion-recovery sequences in particular. Feature 3, present in 12 patients, was optimally seen on the coronal T2-weighted images. Feature 4, seen in 11 patients, was equally well seen in all planes (transverse, coronal, and parallel to the long axes of the hippocampi). Feature 5, seen in 10 patients, was best appreciated on the T2-weighted images in the planes of the long axes of the hippocampi. Histologic investigation of the temporal lobe white matter in the 10 patients with feature 5 demonstrated on the MR scan showed abnormalities in 7 cases. Oligodendroglia cell clusters were found in 6, with concomitant corpora amylacea in 1 case and perivascular macrophages with pigment a sole finding in another case. CONCLUSION: Of the six features found in cases of mesial temporal sclerosis on MR, increased hippocampal signal intensity is the most consistent. A decreased gray-white matter demarcation in the temporal lobe parenchyma is also a frequent feature of this disease. A combination of multiple scanning planes results in an optimal demonstration of lesions.
Asunto(s)
Epilepsia del Lóbulo Temporal/patología , Imagen por Resonancia Magnética , Lóbulo Temporal/patología , Adolescente , Adulto , Amiloide , Atrofia , Femenino , Gliosis/patología , Hipocampo/patología , Humanos , Hipertrofia , Aumento de la Imagen/métodos , Macrófagos/patología , Imagen por Resonancia Magnética/métodos , Masculino , Oligodendroglía/patología , Estudios Retrospectivos , Esclerosis , Lóbulo Temporal/irrigación sanguíneaRESUMEN
OBJECT: The purpose of this study was to compare computerized tomography (CT) angiography and digital subtraction (DS) angiography studies in patients with subarachnoid hemorrhage (SAH) to assess their vascular anatomy relevant to cerebral aneurysm surgery. METHODS: From a prospective series of 100 patients with SAH, the authors selected 73 patients whose CT angiography studies were of adequate quality and in whom DS angiography of both carotid arteries had been performed. Eleven patients with no DS angiographic studies of the vertebrobasilar artery were only evaluated for the anterior half of the circle of Willis. Anterior communicating arteries (ACoAs), both precommunicating anterior cerebral arteries (A1 segments), both posterior communicating arteries (PCoAs), and both precommunicating posterior cerebral arteries (P1 segments) were assessed on CT angiography and DS angiography by two independent observers. CONCLUSIONS: Computerized tomography angiography compares well with DS angiography for visualizing normal-sized arteries, and is superior for visualizing ACoAs and hypoplastic A1 and P, segments. Important preoperative aspects such as dominant A1 segments and PCoAs are equally well seen using either modality. Neither method enabled the authors to visualize more than 50% of PCoAs. Use of CT angiography can provide the required preoperative anatomical information for aneurysm surgery in most patients with SAH.
Asunto(s)
Angiografía de Substracción Digital , Arterias Cerebrales/diagnóstico por imagen , Aneurisma Intracraneal/diagnóstico por imagen , Hemorragia Subaracnoidea/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Adulto , Anciano , Angiografía Cerebral , Arterias Cerebrales/fisiopatología , Circulación Cerebrovascular/fisiología , Círculo Arterial Cerebral/diagnóstico por imagen , Círculo Arterial Cerebral/fisiopatología , Femenino , Humanos , Aneurisma Intracraneal/complicaciones , Aneurisma Intracraneal/fisiopatología , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Sensibilidad y Especificidad , Hemorragia Subaracnoidea/etiología , Hemorragia Subaracnoidea/fisiopatologíaRESUMEN
OBJECT: The purpose of this study was to determine prospectively whether and to what extent computerized tomography (CT) angiography can serve as the sole imaging method for a preoperative workup in patients with ruptured intracranial aneurysms. METHODS: During a 1-year period, all patients who presented to the authors' hospital with subarachnoid hemorrhage demonstrated by unenhanced CT scanning or lumbar puncture underwent CT angiography. Two radiologists evaluated the CT angiography source images and maximum intensity projection slabs and arrived at a consensus. They categorized the quality of the CT angiography as adequate or inadequate and classified aneurysms that were detected as definitely or possibly present. The parent artery of anterior communicating artery aneurysms was identified by asymmetrical anterior cerebral artery size and asymmetrical aneurysm location. The parent artery was indicated by the larger A1 segment in cases of asymmetrical A1 size. Only CT angiograms of adequate quality that revealed aneurysms classified as definitely present and with an unequivocal parent artery were presented to the neurosurgeons, who decided whether preoperative digital subtraction (DS) angiography should still be performed. Forty-nine of the 100 studied patients did not undergo surgery because of poor clinical condition, nonaneurysmal cause of the hemorrhage, or endovascular treatment of the ruptured aneurysm. Of the 51 patients who underwent surgery, radiologists required DS angiography in 17 patients; the imaging technique provided greater certainty in 13 instances. The neurosurgeons required DS angiography 11 times; this provided additional information in two instances. Twenty-three (45%) of the 51 patients were surgically treated successfully on the basis of CT angiography findings alone. CONCLUSIONS: Computerized tomography angiography can replace DS angiography as the preoperative neuroimaging technique in a substantial proportion of patients with ruptured intracranial aneurysms.
Asunto(s)
Angiografía de Substracción Digital/métodos , Angiografía Cerebral/métodos , Aneurisma Intracraneal/diagnóstico por imagen , Hemorragia Subaracnoidea/diagnóstico por imagen , Tomografía Computarizada por Rayos X/métodos , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Aneurisma Roto/diagnóstico por imagen , Aneurisma Roto/cirugía , Niño , Preescolar , Toma de Decisiones Asistida por Computador , Reacciones Falso Negativas , Femenino , Humanos , Lactante , Recién Nacido , Aneurisma Intracraneal/cirugía , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Hemorragia Subaracnoidea/cirugíaRESUMEN
In this paper the effects of reducing the flip angle of the 90-degree observation pulse in inversion recovery imaging are described and analyzed. When incorporated in an IR sequence with a short inversion time (STIR), reduction to the 90-degree pulse allows a significant shortening of the repetition time without loss in contrast, although at the expense of some signal/noise. The generalized STIR sequence thus combines the previously reported advantages of a conventional STIR sequence--suppression of ghost artifacts from abdominal wall movement, suppression of chemical shift and boundary artifacts, additive effects of N(H), T1 and T2 on image contrast--with reduced power deposition and the advantages resulting from shorter repetition times, viz, single heart-beat triggering, increased number of signal averages for suppression of motion artifacts, acquisition of interleaved contiguous slices without cross-talk or considerable time savings when the number of required slices is limited. The proposed method is demonstrated and experimentally verified by imaging experiments on phantoms and human subjects. In principle the method is applicable to all cases where STIR imaging has been proven to be successful.
Asunto(s)
Imagen por Resonancia Magnética/métodos , Encéfalo/anatomía & histología , Humanos , Modelos EstructuralesRESUMEN
Two temporomandibular joints from one specimen were investigated using magnetic resonance imaging and cryosectioning. Magnetic resonance images, photography of the tissue block surface, and on-tape histologic sections were compared. The left joint was imaged and sectioned in a coronal plane, and the right joint in an angulated coronal plane parallel to the long axis of the condyle. The temporomandibular joint disc could be seen in coronal and angulated coronal scans. The posterior band was imaged in angulated coronal magnetic resonance scans throughout the temporomandibular joint both medically and laterally. In coronal scans only parts of the disc proper could be seen, depending on the level of imaging or sectioning. The densely plaited fibrous tissue of the intra-articular tissues could be seen in magnetic resonance imaging, primarily anterior to the condyle; this tissue corresponded to the low signal intensity in magnetic resonance imaging. Medical and lateral disc attachments as well as the temporomandibular joint capsule were imaged in some of the magnetic resonance scans in both the coronal and the angulated coronal scans. In diagnosing anteromedial, medial, and lateral disc displacements, angulated coronal temporomandibular joint scanning is preferred over coronal scanning.
Asunto(s)
Articulación Temporomandibular/anatomía & histología , Anciano , Anciano de 80 o más Años , Crioultramicrotomía , Femenino , Humanos , Imagen por Resonancia Magnética/métodos , Reproducibilidad de los ResultadosRESUMEN
Two temporomandibular joints originating from one specimen were investigated using magnetic resonance imaging and cryosectioning. Magnetic resonance images, photographs of the surface of the tissue block, and on-tape sections were compared. The left joint was imaged and sectioned in a sagittal plane, the right joint in a plane perpendicular to the long axis of the condyle. The densely plaited fibrous tissue of the disc proper correlated extremely well with the low signal intensity in magnetic resonance imaging. The transition between the densely plaited fibrous tissue and the looser tissue of the posterior attachment was located anterior to the thickest part of the intra-articular tissues in most sections of the specimen. The temporomandibular joint disc could be seen in angulated as well as in sagittal magnetic resonance scans. The posterior band was imaged best in angulated magnetic resonance scans throughout the temporomandibular joint.
Asunto(s)
Articulación Temporomandibular/anatomía & histología , Anciano , Anciano de 80 o más Años , Femenino , Secciones por Congelación , Humanos , Imagen por Resonancia Magnética , FotograbarRESUMEN
A 36-year-old Caucasian woman presenting with persisting painful calves after a flu-like illness was diagnosed as having polyarteritis nodosa. Magnetic resonance imaging of the lower legs showed abnormal signal intensity of the outer muscle groups with sparing of the central located muscles. The good clinical response to oral prednisone was supported by improvement of MRI.
Asunto(s)
Músculos/anomalías , Poliarteritis Nudosa/diagnóstico , Poliarteritis Nudosa/patología , Administración Oral , Adulto , Femenino , Humanos , Pierna , Imagen por Resonancia Magnética , Músculos/patología , Poliarteritis Nudosa/tratamiento farmacológico , Prednisona/administración & dosificación , Prednisona/uso terapéuticoRESUMEN
Osteochondroma of the mandibular condyle is extremely rare and may cause signs and symptoms like those seen in patients with temporomandibular joint dysfunction. Differentiation between osteochondroma and condylar hyperplasia is not possible on histologic grounds alone, but the radiographic and intraoperative findings together are usually sufficient to establish a definite diagnosis.
Asunto(s)
Cóndilo Mandibular/patología , Neoplasias Mandibulares/patología , Osteocondroma/patología , Adulto , Bursitis/diagnóstico , Diagnóstico Diferencial , Técnicas de Diagnóstico Quirúrgico , Asimetría Facial/diagnóstico , Humanos , Hiperplasia , Masculino , Cóndilo Mandibular/diagnóstico por imagen , Cóndilo Mandibular/cirugía , Neoplasias Mandibulares/diagnóstico por imagen , Neoplasias Mandibulares/cirugía , Osteocondroma/diagnóstico por imagen , Osteocondroma/cirugía , Síndrome de la Disfunción de Articulación Temporomandibular/diagnóstico , Tomografía Computarizada por Rayos XRESUMEN
Two patients with retroperitoneal cystic lymphangioma are reported with a review of the medical literature. In one, the patient was asymptomatic from the lesion but had a computed tomography (CT) and an ultrasound to evaluate the extent of disease with a known carcinoma of the colon. The second patient presented with an acute abdominal pain requiring surgical management. CT on this patient showed multiple cystlike cavities filled with fluid, in a retroperitoneal location. The preoperative diagnosis of retroperitoneal cystic lymphangioma was confirmed at surgery. Magnetic resonance (MR) performed on the second patient gave better delineation of craniocaudal extent and showed one of the cysts to have probable hemorrhage.
Asunto(s)
Linfangioma/diagnóstico , Neoplasias Retroperitoneales/diagnóstico , Adulto , Diagnóstico por Imagen , Femenino , Humanos , Persona de Mediana EdadRESUMEN
In patients with supratentorial intracerebral haemorrhage (ICH), it is important to discriminate superficial (lobar) and deep (basal ganglia) location, since this has consequences for research and prognosis. Haemorrhages at these sites have different causes and different risk factors. We studied the interobserver variation between three radiologists in classifying fifty large haematomas on CT as deep or lobar. The kappa values were almost perfect, ranging from 0.88 to 0.96. We conclude that the assessment of CT by radiologist is a reliable method to discriminate between lobar versus deep origin even for large intracerebral haematomas.