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1.

Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders.

Hanzl, Alexander; Casement, Ryan; Imrichova, Hana; Hughes, Scott J; Barone, Eleonora; Testa, Andrea; Bauer, Sophie; Wright, Jane; Brand, Matthias; Ciulli, Alessio; Winter, Georg E.

Nat Chem Biol ; 19(3): 323-333, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36329119

2.

Developing and piloting a simulated placement experience for students.

Taylor, Natasha; Wyres, Martyn; Green, Abbie; Hennessy-Priest, Kathleen; Phillips, Carla; Daymond, Emily; Love, Rachel; Johnson, Rebecca; Wright, Jane.

Br J Nurs ; 30(13): S19-S24, 2021 Jul 08.

Artículo en Inglés | MEDLINE | ID: mdl-34251853

3.

Structure-Based Design of a Macrocyclic PROTAC.

Testa, Andrea; Hughes, Scott J; Lucas, Xavier; Wright, Jane E; Ciulli, Alessio.

Angew Chem Int Ed Engl ; 59(4): 1727-1734, 2020 01 20.

Artículo en Inglés | MEDLINE | ID: mdl-31746102

4.

3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation.

Testa, Andrea; Lucas, Xavier; Castro, Guilherme V; Chan, Kwok-Ho; Wright, Jane E; Runcie, Andrew C; Gadd, Morgan S; Harrison, William T A; Ko, Eun-Jung; Fletcher, Daniel; Ciulli, Alessio.

J Am Chem Soc ; 140(29): 9299-9313, 2018 07 25.

Artículo en Inglés | MEDLINE | ID: mdl-29949369

5.

Choline transporter mutations in severe congenital myasthenic syndrome disrupt transporter localization.

Wang, Haicui; Salter, Claire G; Refai, Osama; Hardy, Holly; Barwick, Katy E S; Akpulat, Ugur; Kvarnung, Malin; Chioza, Barry A; Harlalka, Gaurav; Taylan, Fulya; Sejersen, Thomas; Wright, Jane; Zimmerman, Holly H; Karakaya, Mert; Stüve, Burkhardt; Weis, Joachim; Schara, Ulrike; Russell, Mark A; Abdul-Rahman, Omar A; Chilton, John; Blakely, Randy D; Baple, Emma L; Cirak, Sebahattin; Crosby, Andrew H.

Brain ; 140(11): 2838-2850, 2017 Nov 01.

Artículo en Inglés | MEDLINE | ID: mdl-29088354

6.

Sequence determinants of the Caenhorhabditis elegans dopamine transporter dictating in vivo axonal export and synaptic localization.

Robinson, Sarah B; Hardaway, J Andrew; Hardie, Shannon L; Wright, Jane; Glynn, Ryan M; Bermingham, Daniel P; Han, Qiao; Sturgeon, Sarah M; Freeman, Phyllis; Blakely, Randy D.

Mol Cell Neurosci ; 78: 41-51, 2017 01.

Artículo en Inglés | MEDLINE | ID: mdl-27913309

7.

RNA-based regulation of pluripotency.

Wright, Jane E; Ciosk, Rafal.

Trends Genet ; 29(2): 99-107, 2013 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-23146412

8.

Optimization of the choline transporter (CHT) inhibitor ML352: Development of VU6001221, an improved in vivo tool compound.

Bertron, Jeanette L; Ennis, Elizabeth A; Tarr, Christopher J; Wright, Jane; Dickerson, Jonathan W; Locuson, Charles W; Blobaum, Anna L; Rook, Jerri M; Blakely, Randy D; Lindsley, Craig W.

Bioorg Med Chem Lett ; 26(19): 4637-4640, 2016 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-27575469

9.

Functional characterization of C. elegans Y-box-binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes.

Arnold, Andreas; Rahman, Md Masuder; Lee, Man Chun; Muehlhaeusser, Sandra; Katic, Iskra; Gaidatzis, Dimos; Hess, Daniel; Scheckel, Claudia; Wright, Jane E; Stetak, Attila; Boag, Peter R; Ciosk, Rafal.

Nucleic Acids Res ; 42(21): 13353-69, 2014 Dec 01.

Artículo en Inglés | MEDLINE | ID: mdl-25378320

10.

Maxillary lateral incisor agenesis and its relationship to overall tooth size.

Wright, Jane; Bosio, Jose A; Chou, Jang-Ching; Jiang, Shuying S.

J Prosthet Dent ; 115(2): 209-14, 2016 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-26460168

11.

A quantitative RNA code for mRNA target selection by the germline fate determinant GLD-1.

Wright, Jane E; Gaidatzis, Dimos; Senften, Mathias; Farley, Brian M; Westhof, Eric; Ryder, Sean P; Ciosk, Rafal.

EMBO J ; 30(3): 533-45, 2011 Feb 02.

Artículo en Inglés | MEDLINE | ID: mdl-21169991

12.

Defective presynaptic choline transport underlies hereditary motor neuropathy.

Barwick, Katy E S; Wright, Jane; Al-Turki, Saeed; McEntagart, Meriel M; Nair, Ajith; Chioza, Barry; Al-Memar, Ali; Modarres, Hamid; Reilly, Mary M; Dick, Katherine J; Ruggiero, Alicia M; Blakely, Randy D; Hurles, Matt E; Crosby, Andrew H.

Am J Hum Genet ; 91(6): 1103-7, 2012 Dec 07.

Artículo en Inglés | MEDLINE | ID: mdl-23141292

13.

Synthesis and structure-activity relationships of a series of 4-methoxy-3-(piperidin-4-yl)oxy benzamides as novel inhibitors of the presynaptic choline transporter.

Bollinger, Sean R; Engers, Darren W; Ennis, Elizabeth A; Wright, Jane; Locuson, Charles W; Lindsley, Craig W; Blakely, Randy D; Hopkins, Corey R.

Bioorg Med Chem Lett ; 25(8): 1757-1760, 2015 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-25801932

14.

Genome-wide analysis of GLD-1-mediated mRNA regulation suggests a role in mRNA storage.

Scheckel, Claudia; Gaidatzis, Dimos; Wright, Jane E; Ciosk, Rafal.

PLoS Genet ; 8(5): e1002742, 2012 May.

Artículo en Inglés | MEDLINE | ID: mdl-22693456

15.

Correction to "3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation".

Testa, Andrea; Lucas, Xavier; Castro, Guilherme V; Chan, Kwok-Ho; Wright, Jane E; Runcie, Andrew C; Gadd, Morgan S; Harrison, William T A; Ko, Eun-Jung; Fletcher, Daniel; Ciulli, Alessio.

J Am Chem Soc ; 141(18): 7644, 2019 May 08.

Artículo en Inglés | MEDLINE | ID: mdl-31017404

16.

Evaluation of an organisational-level monetary incentive to promote the health and wellbeing of workers in small and medium-sized enterprises: A mixed-methods cluster randomised controlled trial.

Al-Khudairy, Lena; Akram, Yasmin; Watson, Samuel I; Kudrna, Laura; Hofman, Joanna; Nightingale, Madeline; Alidu, Lailah; Rudge, Andrew; Rawdin, Clare; Ghosh, Iman; Mason, Frances; Perera, Chinthana; Wright, Jane; Boachie, Joseph; Hemming, Karla; Vlaev, Ivo; Russell, Sean; Lilford, Richard J.

PLOS Glob Public Health ; 3(7): e0001381, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37410723

17.

Clinical supervision: a review of the evidence base.

Wright, Jane.

Nurs Stand ; 27(3): 44-9, 2012.

Artículo en Inglés | MEDLINE | ID: mdl-23248885

18.

Optimisation of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.

Ray, Peter; Wright, Jane; Adam, Julia; Boucharens, Sylviane; Black, Darcey; Brown, Angus R; Epemolu, Ola; Fletcher, Dan; Huggett, Margaret; Jones, Phil; Laats, Steven; Lyons, Amanda; de Man, Jos; Morphy, Richard; Sherborne, Brad; Sherry, Lorcan; Straten, Nicole van; Westwood, Paul; York, Mark.

Bioorg Med Chem Lett ; 21(4): 1084-8, 2011 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-21251828

19.

Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.

Ray, Peter; Wright, Jane; Adam, Julia; Bennett, Johnathan; Boucharens, Sylviane; Black, Darcey; Cook, Andrew; Brown, Angus R; Epemolu, Ola; Fletcher, Dan; Haunso, Anders; Huggett, Margaret; Jones, Phil; Laats, Steven; Lyons, Amanda; Mestres, Jordi; de Man, Jos; Morphy, Richard; Rankovic, Zoran; Sherborne, Brad; Sherry, Lorcan; van Straten, Nicole; Westwood, Paul; Zaman, Guido Z R.

Bioorg Med Chem Lett ; 21(1): 97-101, 2011 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-21145740

20.

Tachycardia, reduced vagal capacity, and age-dependent ventricular dysfunction arising from diminished expression of the presynaptic choline transporter.

English, Brett A; Appalsamy, Martin; Diedrich, Andre; Ruggiero, Alicia M; Lund, David; Wright, Jane; Keller, Nancy R; Louderback, Katherine M; Robertson, David; Blakely, Randy D.

Am J Physiol Heart Circ Physiol ; 299(3): H799-810, 2010 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-20601463

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