Role of environmental ownership and associated parameters to assess green patents in technologies with environmental scanning system as a controlling factor.

There is a general conception that environmental firms are more adapted to green solutions, and environmental patents are just lagging. The existing literature has paid particular attention to identifying obstacles and situational factors associated with established firms going green and has concentrated on how and why established businesses are becoming more financially viable and ecologically sustainable. In changing environment, manufacturing companies are direct contributors to environmental impacts. Increased awareness of consumers about the environment puts a handful amount of pressure on manufacturing companies to care about the environment. It also asserts unseen pressure on the financial performance of the companies. Therefore, it is time to go for green patenting of such firms while satisfying the eco-innovation and environmental scanning process. Moreover, Environmental ownership and its associated parameters keenly monitor this aspect. This paper evaluates the performance of the support vector machine (SVM/SVR) approach for estimating patents in environment-related technologies (PERT) in China from 1995 to 2021. For this work, six independent variables related to environmental ownership and environment-related technologies were selected, which include medium and high-tech exports (MHTE), green patents applicants (GPA), listed domestic companies (LDC), human capital index (HCI), self-employment (SE), and manufacturing value added in GDP (MVA). Data for dependent and independent variables were gathered from the World Bank (WB) official data bank portal. To make an initial understanding of the data basic statistical summary was computed in R programming to see the mean, minimum and maximum values in the data set. A correlation matrix plot showed the association between dependent and independent variables. SVM/SVR with radial basis function (RBF) regression was applied to see the impact of contributing parameters that influence PERT. For PERT, the model generated 0.95 R2 (RMSE = 92.43). The results of the SVR showed that the association among environmental parameters is strong. With a value of 4.82, the strongest coefficient in the SVR model is PAR. This work is novel and will benefit the manufacturing sector, analysts, policymakers, environmentalists as how green patenting can boost the eco innovation and environmental ownership and scanning system with advance technologies and practices.

The relationship between anthropometric indices and type 2 diabetes mellitus among adults in north-east China.

OBJECTIVE: The present study was performed to test the predictive value of different cut-off points of anthropometric parameters for the presence of type 2 diabetes (T2DM) or glucose tolerance abnormalities in north-east Chinese adults. DESIGN: Multistage random cluster sampling method in a cross-sectional study. SETTING: Height, body weight, maximal body weight in the past, waist and hip circumferences, blood pressure, 2 h post-load glucose and other lifestyle factors were measured. SUBJECTS: We used data from 1058 adults aged 20 years or over, selected in the city of Mudanjiang, in 2005. RESULTS: BMI, maximal BMI in the past (MAXBMI), waist:hip ratio (WHR), waist:height ratio (WHtR) and waist circumference (WC) were significantly correlated with each other. Partial correlation coefficients between WHtR and WC, and between MAXBMI and BMI, were higher than those between the other indices. The association of anthropometric indices with T2DM or glucose tolerance abnormalities was significantly highest for the collaboration cut-off points of MAXBMI (≥ 23.0 kg/m(2) for T2DM, ≥ 22.0 kg/m(2) for glucose tolerance abnormalities) with WHtR (≥ 0.52). Areas under the receiver-operating characteristic curves also showed that WHtR was a better anthropometric index that discriminated between the presence and absence of T2DM and an excellent indicator with high Youden's index. CONCLUSIONS: MAXBMI combined with WHtR was a better anthropometric index associated with T2DM or glucose tolerance abnormalities. The combined use of these two measures is a good choice for T2DM prevention and screening.

Trauma Prevalence and Its Association With Health-Related Quality of Life in Pregnant Persons with Opioid Use Disorder.

OBJECTIVES: Trauma screening is recommended for pregnant persons with opioid use disorder (OUD), but there is limited literature on screening results from buprenorphine treatment. This study's objectives were to 1) describe the types, and severity, of traumatic events reported and 2) evaluate the associations between trauma and health-related quality of life (HRQoL). METHODS: Baseline data from an ongoing trial were analyzed. Participants were 155 pregnant persons with OUD receiving, or enrolling in, buprenorphine treatment at one of 13 sites. The experience, and relative severity, of 14 high magnitude stressors were assessed with the trauma history screen. The Patient-Reported Outcomes Measurement Information System-29+2 was used to assess 8 HRQoL domains. RESULTS: Traumatic stressors were reported by 91% of the sample (n = 155), with 54.8% reporting a lifetime persisting posttraumatic distress (PPD) event and 29.7% reporting a childhood PPD event. The most prevalent lifetime PPD event was sudden death of a close family/friend (25.8%); physical abuse was the most prevalent childhood PPD event (10.3%). Participants with lifetime PPD, relative to no PPD, reported significantly greater pain interference (P = 0.02). Participants with childhood PPD, relative to no PPD, had significantly worse HRQoL overall (P = 0.01), and worse pain intensity (P = 0.002), anxiety (P = 0.003), depression (P = 0.007), fatigue (P = 0.002), and pain interference (P < 0.001). CONCLUSIONS: A majority of pregnant persons enrolled/enrolling in buprenorphine treatment reported persisting posttraumatic distress with sudden death of close family/friend being the most prevalent originating event; clinicians should consider the impact that the opioid-overdose epidemic may be having in increasing trauma exposure in patients with OUD.

Surgical resection and liposomal amphotericin B to treat cavitary pulmonary zygomycosis in a patient with diabetes.

We describe a 24-year-old man with type 1 diabetes mellitus and a cavitary lesion in the right upper lobe, caused by a zygomycete. Surgical resection plus liposomal amphotericin B therapy was successful. We discuss predisposing condition, clinical findings, diagnosis, and treatment of pulmonary zygomycosis.

Osteoinductive nanohydroxyapatite bone substitute prepared via in situ hydrothermal transformation of cuttlefish bone.

The capacity to induce a rapid and controlled healing of bone defects is critical for a bone substitute. Previous studies have reported hydrothermal transformation (HT) of aragonite from cuttlebone (CB) to cuttlebone hydroxyapatite (CBHA). However, the biocompatibility and in vivo characteristic of CBHA have not been fully investigated. We fabricated CBHA via the in situ HT of aragonite from CB. This CBHA exhibited a highly porous structure and nanoscaled surface morphology with a significantly higher protein adsorption rate than CB. Marrow mesenchymal stem cells (MSCs) were seeded and cultured on the CBHA and CB to evaluate their influence on cell proliferation and differentiation. According to scanning electronic microscopy observation and MTT assay, the MSCs adhered and proliferated well on both the CBHA and CB. Compared with the cells on the CB, the MSCs on CBHA exhibited enhanced alkaline phosphatase activity and osteocalcin levels after 13 days of culture. In vivo testing revealed that CBHA could induce ectopic bone formation after implantation, while no bone formation being observed in the CB. These findings demonstrated that a nanoscaled and osteoinductive bone substitute could be produced by hydrothermally transforming an aragonite of CB into a hydroxyapatite.