RESUMEN
The goal of this work was to study the impact of the concurrent application of mineral water from the lake of Shira (Khakassia) and phytotherapeutic preparations on the secretory and excretory stomach functions. Mineral water from the lake of Shira belongs to highly mineralized (18.4 g/l) hydrocarbonate sodium-magnesium waters with alkaline reaction (pH 8.9). Phytotherapeutic preparations included the following herbs: common St. John's wort--4 parts (6.0 g per liter), bay willow--5 parts (7.5 g), peppermint: 5 parts (7.5 g), quinquelobate motherwort--3 parts (4.5 g), and shelf fungus--3 parts (4.5 g).
Asunto(s)
Jugo Gástrico/metabolismo , Mucosa Gástrica/efectos de los fármacos , Aguas Minerales/administración & dosificación , Preparaciones de Plantas/farmacología , Animales , Jugo Gástrico/química , Mucosa Gástrica/metabolismo , Masculino , Preparaciones de Plantas/administración & dosificación , Ratas , Ratas Wistar , Tasa de Secreción/efectos de los fármacosRESUMEN
The proposed method shows the velocity of gastroduodenal epitheliocyte exchange by evaluating the total content of nucleic acids in gastric and duodenal aspirates. The concentration of nucleic acids in the cavitary secretion phase reflects the state of the gastroduodenal mucosa and physicochemical properties of the mucus. Sixty patients with gastroduodenal diseases (chronic gastritis, chronic duodenitis from surface to atrophic and during exacerbation) were examined. Changes in the distribution of nucleic acids by phases of cavitary secretion were revealed. A decrease in the total content of nucleic acids in cavitary contents was paralleled by decreased activity of chronic gastritis and duodenitis and normalization of colloid and gel-forming properties of the mucus, which manifested by an essential increase of nucleic acids concentrations in the mucus and decrease in the gastric juice.