RESUMEN
The comparison shows that both Shiquandabu pills and Shiquandabu liquor are efficacious in strengthening the immunological functions of mice. No significant difference has been found between the two forms of preparation. There exists a good dose-efficacy relationship for the pills in immunological functions.
Asunto(s)
Medicamentos Herbarios Chinos/farmacología , Animales , Medicamentos Herbarios Chinos/administración & dosificación , Femenino , Técnica de Placa Hemolítica , Macrófagos/efectos de los fármacos , Masculino , Ratones , Tamaño de los Órganos/efectos de los fármacos , Fagocitosis/efectos de los fármacos , Bazo/anatomía & histología , Timo/anatomía & histologíaRESUMEN
The effects of Guifu Dihuang Pills extract were observed in rabbit IgG accelerated mouse nephritis model induced by nephrotoxic serum. The results showed that this preparation could increase serum albumin, reduce urine protein, serum urea nitrogen and total cholesterol in serum, and improve the histological lesions in kidneys. The effects of Guifu Dihuang Pills extract in dosages of 0.3g/kg and 1.2g/kg were similar to those of cyclophosphamide 0.015g/kg.